How to adjust antibiotics dose in acute kidney injury (AKI) patient?
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Thanks for your response,
Thanks for your question,
- Responded 21 Oct 2019 · The general advice is that you would need to look at the SPC for each drug and individualise it for condition, patient, characteristics (age weight etc) and the antibiotic of choice. There are generic guidelines/articles out there that may help e.g. “KHA-CARI guideline: KHA-CARI adaptation of the KDIGO Clinical Practice Guideline for Acute Kidney Injury”  and “Ceftriaxone: Dose adjustment for renal impairment” . I dare say there are other resources out there that a quick search can unearth. References 1) http://www.cari.org.au/CKD/CKD%20aki/AKI%20Summary.pdf 2) https://www.gloshospitals.nhs.uk/gps/antimicrobial-resources/a-z-bugs-and-drugs/ceftriaxone-dose-adjustment-renal-impairment/ Conflict of interest declaration: None
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