Latest & greatest articles for acetaminophen

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Top results for acetaminophen

41. Prenatal acetaminophen and outcomes in children

Prenatal acetaminophen and outcomes in children Prenatal acetaminophen use and outcomes in children - American Journal of Obstetrics & Gynecology Email/Username: Password: Remember me Search Terms Search within Search Share this page: Access provided by Volume 216, Issue 3, Pages B14–B15 Prenatal acetaminophen use and outcomes in children Society for Maternal-Fetal Medicine (SMFM) Publications Committee ∗ Society for Maternal-Fetal Medicine, 409 12 St. SW, Washington, DC 20024, USA. pubs (...) @smfm.org DOI: | Publication History Published online: January 23, 2017 Expand all Collapse all The practice of medicine continues to evolve, and individual circumstances will vary. This publication reflects information available at the time of its submission for publication and is neither designed nor intended to establish an exclusive standard of perinatal care. This publication is not expected to reflect the opinions of all members of the Society for Maternal-Fetal Medicine. Acetaminophen is the most

2017 Society for Maternal-Fetal Medicine

42. Paracetamol (acetaminophen) with or without codeine or dihydrocodeine for neuropathic pain in adults. (PubMed)

Paracetamol (acetaminophen) with or without codeine or dihydrocodeine for neuropathic pain in adults. Paracetamol, either alone or in combination with codeine or dihydrocodeine, is commonly used to treat chronic neuropathic pain. This review sought evidence for efficacy and harm from randomised double-blind studies.To assess the analgesic efficacy and adverse events of paracetamol with or without codeine or dihydrocodeine for chronic neuropathic pain in adults.We searched the Cochrane Central

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2016 Cochrane

43. Limited Knowledge of Acetaminophen in Patients with Liver Disease (PubMed)

Limited Knowledge of Acetaminophen in Patients with Liver Disease Background and Aims: Unintentional acetaminophen overdose remains the leading cause of acute liver failure in the United States. Patients with underlying liver disease are at higher risk of poor outcomes from acetaminophen overdose. Limited knowledge of acetaminophen may be a preventable contributor to elevated rates of overdose and thus acute liver failure. The purpose of this study is to assess knowledge of acetaminophen dosing (...) and presence of acetaminophen in common combination products in patients with liver disease. Methods: We performed a cross-sectional study of patients with liver disease at the Pfleger Liver Institute at the University of California, Los Angeles between June 2015 and August 2016. Patients completed a demographic questionnaire and an acetaminophen knowledge survey. Additional information was obtained from the medical record. Results: Of 401 patients with liver disease, 30 (15.7%) were able to correctly

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2016 Journal of clinical and translational hepatology

44. Acetaminophen for Pain or Fever: Clinical Effectiveness and Safety

Acetaminophen for Pain or Fever: Clinical Effectiveness and Safety Acetaminophen for Pain or Fever: Clinical Effectiveness and Safety | CADTH.ca Find the information you need Acetaminophen for Pain or Fever: Clinical Effectiveness and Safety Acetaminophen for Pain or Fever: Clinical Effectiveness and Safety Published on: September 9, 2016 Project Number: RA0864-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the clinical effectiveness (...) and safety of different individual doses of acetaminophen for patients with pain or fever? What is the clinical effectiveness and safety of doses in excess of the recommended daily maximum dose (4 g) for patients with pain or fever? What is the safety of chronic use of acetaminophen? Key Message Thirty-three systematic reviews and meta-analyses were identified regarding the effectiveness and safety of acetaminophen. Tags acetaminophen, Tylenol, paracetamol Files Rapid Response Reference List Published

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

45. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. (PubMed)

Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. Studies have suggested an association between frequent acetaminophen use and asthma-related complications among children, leading some physicians to recommend that acetaminophen be avoided in children with asthma; however, appropriately designed trials evaluating this association in children are lacking.In a multicenter, prospective, randomized, double-blind, parallel-group trial, we enrolled 300 children (age range (...) , 12 to 59 months) with mild persistent asthma and assigned them to receive either acetaminophen or ibuprofen when needed for the alleviation of fever or pain over the course of 48 weeks. The primary outcome was the number of asthma exacerbations that led to treatment with systemic glucocorticoids. Children in both groups received standardized asthma-controller therapies that were used in a simultaneous, factorially linked trial.Participants received a median of 5.5 doses (interquartile range, 1.0

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2016 NEJM

46. Acetaminophen and Asthma - A Small Sigh of Relief? (PubMed)

Acetaminophen and Asthma - A Small Sigh of Relief? 27532835 2016 08 24 2018 12 02 1533-4406 375 7 2016 Aug 18 The New England journal of medicine N. Engl. J. Med. Acetaminophen and Asthma--A Small Sigh of Relief? 684-5 10.1056/NEJMe1607629 Litonjua Augusto A AA From the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School - both in Boston. eng Editorial Comment United States N Engl J Med 0255562 0028-4793 362O9ITL9D (...) Acetaminophen AIM IM N Engl J Med. 2016 Aug 18;375(7):619-30 27532828 Acetaminophen Asthma drug therapy Humans 2016 8 18 6 0 2016 8 18 6 0 2016 8 25 6 0 ppublish 27532835 10.1056/NEJMe1607629

2016 NEJM

47. 1000 mg versus 650 mg Acetaminophen for Pain or Fever: A Review of the Clinical Efficacy

1000 mg versus 650 mg Acetaminophen for Pain or Fever: A Review of the Clinical Efficacy 1000 mg versus 650 mg Acetaminophen for Pain or Fever: A Review of the Clinical Efficacy | CADTH.ca Find the information you need 1000 mg versus 650 mg Acetaminophen for Pain or Fever: A Review of the Clinical Efficacy 1000 mg versus 650 mg Acetaminophen for Pain or Fever: A Review of the Clinical Efficacy Published on: June 17, 2016 Project Number: RC0786-000 Product Line: Research Type: Drug Report Type (...) : Summary with Critical Appraisal Result type: Report Question What is the comparative clinical efficacy of 1000 mg acetaminophen compared with 600/650 mg acetaminophen for the treatment of pain? What is the comparative clinical efficacy of 1000 mg acetaminophen compared with 600/650 mg acetaminophen for managing fever? Key Message Acetaminophen 1000 mg single dose led to a higher percentage of people with at least 50% of pain relief over six hours, and a larger decrease in pain intensity, as compared

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

48. Paracetamol (acetaminophen) for acute treatment of episodic tension-type headache in adults. (PubMed)

Paracetamol (acetaminophen) for acute treatment of episodic tension-type headache in adults. Tension-type headache (TTH) affects about 1 person in 5 worldwide. It is divided into infrequent episodic TTH (fewer than one headache per month), frequent episodic TTH (two to 14 headaches per month), and chronic TTH (15 headache days a month or more). Paracetamol (acetaminophen) is one of a number of analgesics suggested for acute treatment of headaches in frequent episodic TTH.To assess the efficacy

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2016 Cochrane

49. Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update (PubMed)

Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional overdose of acetaminophen (APAP) has affected patients for decades, and involves the cornerstone metabolic pathways which take place in the microsomes within hepatocytes. APAP hepatotoxicity remains a global issue; in the United States, in particular, it accounts for more than 50% of overdose-related acute liver failure and approximately 20

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2016 Journal of clinical and translational hepatology

50. 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction

400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction UTCAT2994, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction Clinical Question In patients (...) receiving acetaminophen (paracetamol) and ibuprofen combination therapy, what is the effective dosage to relieve postoperative pain? Clinical Bottom Line For patients with postoperative pain, 400 mg ibuprofen/1000 mg acetaminophen (paracetamol) is the suggested effective dosage for short-term pain management. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Mehlisch/2010 234 patients post extraction

2016 UTHSCSA Dental School CAT Library

51. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. (PubMed)

Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 27028922 2016 03 31 2018 12 02 1533-4406 374 13 2016 03 31 The New England journal of medicine N. Engl. J. Med. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 1291 10.1056/NEJMc1601361 Patel Jayshil J Medical College of Wisconsin, Milwaukee, WI jpatel2@mcw.edu. eng Letter Comment United States N Engl J Med 0255562 0028-4793 362O9ITL9D Acetaminophen AIM IM N Engl J Med. 2015 Dec 3;373(23 (...) ):2215-24 26436473 N Engl J Med. 2016 Mar 31;374(13):1292-3 27028921 Acetaminophen therapeutic use Female Fever drug therapy Humans Infection drug therapy Male 2016 3 31 6 0 2016 3 31 6 0 2016 4 1 6 0 ppublish 27028922 10.1056/NEJMc1601361 10.1056/NEJMc1601361#SA1

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2016 NEJM

52. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. (PubMed)

Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 27028921 2016 03 31 2018 12 02 1533-4406 374 13 2016 03 31 The New England journal of medicine N. Engl. J. Med. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 1292-3 10.1056/NEJMc1601361 Young Paul P Saxena Manoj M Beasley Richard R eng Letter Comment United States N Engl J Med 0255562 0028-4793 362O9ITL9D Acetaminophen AIM IM N Engl J Med. 2015 Dec 3;373(23):2215-24 26436473 N Engl J Med (...) . 2016 Mar 31;374(13):1291 27028922 N Engl J Med. 2016 Mar 31;374(13):1291-2 27028923 N Engl J Med. 2016 Mar 31;374(13):1292 27028924 Acetaminophen therapeutic use Female Fever drug therapy Humans Infection drug therapy Male 2016 3 31 6 0 2016 3 31 6 0 2016 4 1 6 0 ppublish 27028921 10.1056/NEJMc1601361 10.1056/NEJMc1601361#SA4

2016 NEJM

53. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. (PubMed)

Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 27028923 2016 03 31 2018 12 02 1533-4406 374 13 2016 03 31 The New England journal of medicine N. Engl. J. Med. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 1291-2 10.1056/NEJMc1601361 Leiner Steven S Mission Neighborhood Health Center, San Francisco, CA steven.leiner@gmail.com. eng Letter Comment United States N Engl J Med 0255562 0028-4793 362O9ITL9D Acetaminophen AIM IM N Engl J Med (...) . 2015 Dec 3;373(23):2215-24 26436473 N Engl J Med. 2016 Mar 31;374(13):1292-3 27028921 Acetaminophen therapeutic use Female Fever drug therapy Humans Infection drug therapy Male 2016 3 31 6 0 2016 3 31 6 0 2016 4 1 6 0 ppublish 27028923 10.1056/NEJMc1601361 10.1056/NEJMc1601361#SA2

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2016 NEJM

54. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. (PubMed)

Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 27028924 2016 03 31 2018 12 02 1533-4406 374 13 2016 03 31 The New England journal of medicine N. Engl. J. Med. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. 1292 10.1056/NEJMc1601361 Arik Gunes G Gazi University, Ankara, Turkey guneseken@yahoo.com. Şengül Ayçiçek Gözde G Gazi University, Ankara, Turkey guneseken@yahoo.com. Ulger Zekeriya Z Gazi University, Ankara, Turkey guneseken (...) @yahoo.com. eng Letter Comment United States N Engl J Med 0255562 0028-4793 362O9ITL9D Acetaminophen AIM IM N Engl J Med. 2015 Dec 3;373(23):2215-24 26436473 N Engl J Med. 2016 Mar 31;374(13):1292-3 27028921 Acetaminophen therapeutic use Female Fever drug therapy Humans Infection drug therapy Male 2016 3 31 6 0 2016 3 31 6 0 2016 4 1 6 0 ppublish 27028924 10.1056/NEJMc1601361 10.1056/NEJMc1601361#SA3

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2016 NEJM

55. Preoperative Acetaminophen Use in Hysterectomy to Reduce Postoperative Opioid Consumption

Preoperative Acetaminophen Use in Hysterectomy to Reduce Postoperative Opioid Consumption "Preoperative Acetaminophen Use in Hysterectomy to Reduce Postoperative" by Anna Lee < > > > > > Title Author Date of Graduation Summer 8-13-2016 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Annjanette Sommers Second Advisor Brent Norris Rights . Abstract Background: Hysterectomy is a common surgery amongst females and is occasionally considered (...) a same-day outpatient surgery. There is a lack of adequate postoperative pain control thus leading to extended use of postoperative opioid use. As a result, in addition to other postoperative side effects, patients suffer from adverse side effects of opioid use, including sedation, respiratory depression, constipation, nausea, and pruritus. This indirectly prolongs patients’ hospital stay and recovery. There have been recent studies suggesting non-opioids, such as acetaminophen, could decrease opioid

2016 Pacific University EBM Capstone Project

56. AcetaMINophen for Back Osteoarthritis Pain: Is the effect in the name?

AcetaMINophen for Back Osteoarthritis Pain: Is the effect in the name? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,400 family physicians, family medicine residents, and medical students in Alberta. Established over sixty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research (...) . www.acfp.ca September 26, 2016 AcetaMINophen for Back and Osteoarthritis Pain: Is the effect in the name? Clinical Question: Is acetaminophen effective for the management of back pain or osteoarthritis? Bottom Line: Acetaminophen is not efficacious for back pain, and provides no clinically meaningful impact on osteoarthritis. There are many other better interventions for these conditions like: short-term oral NSAIDs for back pain; topical NSAIDs or intra-articular steroids for osteoarthritis; and exercise

2016 Tools for Practice

57. Comparative Analgesic Efficacy of Oxycodone/Acetaminophen Versus Hydrocodone/Acetaminophen for Short-term Pain Management in Adults Following ED Discharge (PubMed)

Comparative Analgesic Efficacy of Oxycodone/Acetaminophen Versus Hydrocodone/Acetaminophen for Short-term Pain Management in Adults Following ED Discharge The objective was to test the hypothesis that oxycodone/acetaminophen provides superior analgesia to hydrocodone/acetaminophen for the treatment of acute extremity pain following emergency department (ED) discharge.This was a prospective, randomized, double-blind clinical trial of nonelderly adult ED patients with acute musculoskeletal (...) extremity pain, randomly allocated at discharge to receive oxycodone/acetaminophen (5 mg/325 mg) or hydrocodone/acetaminophen (5 mg/325 mg). The primary outcome was the between-group difference in improvement in numerical rating scale (NRS) pain scores over a 2-hour period following the most recent ingestion of study drug, obtained during telephone contact 24 hours after ED discharge. Secondary outcomes included proportionate decrease in pain, comparative side-effect profiles, and patient satisfaction.A

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2015 EvidenceUpdates

58. Tramadol Plus Acetaminophen for the Management of Pain in Adult Patients: Clinical Effectiveness

Tramadol Plus Acetaminophen for the Management of Pain in Adult Patients: Clinical Effectiveness Tramadol Plus Acetaminophen for the Management of Pain in Adult Patients: Clinical Effectiveness | CADTH.ca Find the information you need Tramadol Plus Acetaminophen for the Management of Pain in Adult Patients: Clinical Effectiveness Tramadol Plus Acetaminophen for the Management of Pain in Adult Patients: Clinical Effectiveness Published on: November 3, 2015 Project Number: RB0927-000 Product Line (...) : Research Type: Drug Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of tramadol plus acetaminophen for the management of pain in adult patients? Key Message Two randomized controlled trials and four non-randomized studies were identified regarding the clinical effectiveness of tramadol plus acetaminophen for the management of pain in adult patients. Tags acetaminophen, anesthesia, paracetamol, tramadol, Tramacet Files Rapid Response Summary of Abstracts

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

59. Comparing the Therapeutic Effectiveness of N-acetylcysteine with the Combination of N-acetyl Cysteine and Cimetidine in Acute Acetaminophen Toxicity: A Double-Blinded Clinical Trial. (PubMed)

Comparing the Therapeutic Effectiveness of N-acetylcysteine with the Combination of N-acetyl Cysteine and Cimetidine in Acute Acetaminophen Toxicity: A Double-Blinded Clinical Trial. N-acetylcysteine (NAC) has been used as a classic treatment for hepatotoxicity induced by N-acetyl-p-benzoquinone imine (NAPQI) as a metabolite of acetaminophen. However, cimetidine theoretically can reduce the production of toxic metabolites through the inhibition of cytochrome p450, and it recently was proposed (...) as a complementary treatment for acetaminophen toxicity.The aim of this study was to compare the effects of treating acute acetaminophen toxicity with NAC alone and with a combination of NAC and cimetidine.From October 2013 to March 2014, 105 patients suspected of acetaminophen toxicity who had paraclinical confirmation of toxicity requiring medical treatment (based on the risk assessment nomogram of acetaminophen serum level) were enrolled in this double-blind, randomized, controlled trial at Imam Reza Hospital

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2015 Electronic physician

60. Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial. (PubMed)

Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain: A Randomized Clinical Trial. Low back pain (LBP) is responsible for more than 2.5 million visits to US emergency departments (EDs) annually. These patients are usually treated with nonsteroidal anti-inflammatory drugs, acetaminophen, opioids, or skeletal muscle relaxants, often in combination.To compare functional outcomes and pain at 1 week and 3 months after an ED visit for acute LBP among (...) commonly used to measure LBP and related functional impairment on which 0 indicates no functional impairment and 24 indicates maximum impairment. Beginning in April 2012, a total of 2588 patients were approached for enrollment. Of the 323 deemed eligible for participation, 107 were randomized to receive placebo and 108 each to cyclobenzaprine and to oxycodone/acetaminophen. Follow-up was completed in December 2014.All participants were given 20 tablets of naproxen, 500 mg, to be taken twice a day

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2015 JAMA