Latest & greatest articles for acetaminophen

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Top results for acetaminophen

81. Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control?

Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control? SystematicReviewSnapshot TAKE-HOME MESSAGE Combination treatment with ibuprofen and acetaminophen is bene?cial over either agent alone for sustained fever reduction in children older than 6 months. METHODS DATA SOURCES The author searched MEDLINE (1948 to May 2011) and EMBASE (1980 to May 2011). Additional hand searches of references from the UK National Institute for Health and Clinical Excellence guidelines (...) Standards of Re- porting Trials (CONSORT) crite- ria to score the quality of the included trials and abstract the data. Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control? EBEM Commentator Rohith R. Malya, MD, MSc Department of Emergency Medicine University of Texas at Houston Houston, TX Results Seventrialswereretrievedandallmet the inclusion criteria and most of the itemsontheCONSORTchecklist.Dif- ferences in dosing interval limited di- rect comparison between any 2

2013 Annals of Emergency Medicine Systematic Review Snapshots

82. Hydrocodone-acetaminophen for pain control in first-trimester surgical abortion: a randomized controlled trial (PubMed)

Hydrocodone-acetaminophen for pain control in first-trimester surgical abortion: a randomized controlled trial Although hydrocodone-acetaminophen is commonly used for pain control in first-trimester abortion, the efficacy of oral opioids for decreasing pain has not been established. Our objective was to estimate the effect of hydrocodone-acetaminophen on patient pain perception during first-trimester surgical abortion.We conducted a randomized, double-blinded, placebo-controlled trial. Patients (...) (before 11 weeks of gestation) received standard premedication (ibuprofen and lorazepam) and a paracervical block with the addition of 10 mg hydrocodone and 650 mg acetaminophen or placebo 45-90 minutes before surgical abortion. A sample size of 120 was calculated to provide 80% power to show a 15-mm difference (α=0.05) in the primary outcome of pain with uterine aspiration (100-mm visual analog scale). Secondary outcomes were pain at additional time points, satisfaction, side effects, adverse events

2012 EvidenceUpdates

83. Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety

Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Codeine (...) and acetaminophen for pain relief: a review of the clinical efficacy and safety. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2012 Authors' conclusions Based on this review, both codeine and acetaminophen/codeine provide better chronic pain relief than placebo. Chronic use of acetaminophen at doses higher than 2000 mg per day may be associated with increased risk of gastrointestinal events, liver toxicity, and renal dysfunction or failure. This review found evidence of increased risk

2012 Health Technology Assessment (HTA) Database.

84. Use of Aspirin, Other Nonsteroidal Anti-Inflammatory Drugs, and Acetaminophen and Postmenopausal Breast Cancer Incidence (PubMed)

Use of Aspirin, Other Nonsteroidal Anti-Inflammatory Drugs, and Acetaminophen and Postmenopausal Breast Cancer Incidence The associations between use of aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen and breast cancer incidence in postmenopausal women are uncertain. We examined these associations with breast cancer, both overall and by molecular subtype.We observed 84,602 postmenopausal women, free of cancer in 1980, until June 2008 and prospectively collected (...) progesterone receptor (PR) -positive breast cancer (95% CI, 0.77 to 1.06; P(trend) = 0.17), and 0.91 for ER-negative PR-negative breast cancer (95% CI, 0.68 to 1.22; P(trend) = 0.97). Results did not vary appreciably by past or current use, days per week of use, or dosage of use. Use of other NSAIDs and acetaminophen was largely not significantly associated with breast cancer risk. Additionally, use of higher doses of each analgesic (≥ six tablets per week) for more than 10 years was generally

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2012 EvidenceUpdates

85. Codeine and Acetaminophen for Pain Relief: A Review of the Clinical Efficacy and Safety

Codeine and Acetaminophen for Pain Relief: A Review of the Clinical Efficacy and Safety Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources and a summary of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed (...) to CADTH. Links: This report may contain links to other information available on the websites of third parties on the Internet. CADTH does not have control over the content of such sites. Use of third party sites is governed by the owners’ own terms and conditions. TITLE: Codeine and Acetaminophen for Pain Relief: A Review of the Clinical Efficacy and Safety DATE: 12 April 2012 CONTEXT AND POLICY ISSUES Pain has been defined as “an unpleasant sensory and emotional experience arising from actual

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

86. Liver Toxicity in Patients using Acetaminophen

Liver Toxicity in Patients using Acetaminophen UTCAT842, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Liver Toxicity In Patients Using Acetaminophen Clinical Question In patients with Post-operative pain, does the use of acetaminophen cause hepatotoxicity versus other analgesics? Clinical Bottom Line Use of acetaminophen has caused increased rates of hepatotoxicity. (See Comments on the CAT below) Best Evidence (you (...) may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Guggenheimer/2011 N/A Systematic Review Key results Increased use of acetaminophen has increased the number of cases of hepatotoxicity. Since acetaminophen is found in many analgesics, unintentional overdose can occur. Evidence Search Liver toxicity and acetaminophen Comments on The Evidence The study is a systematic review of articles. The authors reviewed the literature

2011 UTHSCSA Dental School CAT Library

87. NSAIDs vs acetaminophen in knee and hip osteoarthritis: a systematic review regarding heterogeneity influencing the outcomes

NSAIDs vs acetaminophen in knee and hip osteoarthritis: a systematic review regarding heterogeneity influencing the outcomes Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

88. Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain (PubMed)

Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain There has been a trend over recent years for combining a nonsteroidal antiinflammatory drug (NSAID) with paracetamol (acetaminophen) for pain management. However, therapeutic superiority of the combination of paracetamol and an NSAID over either drug alone remains controversial. We evaluated the efficacy of the combination

2010 EvidenceUpdates

89. Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain

Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed (...) acetaminophen as an effective and safe reliever of acutepostoperative pain James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion A single standard dose of acetaminophen relieves moderate to severe postoperative pain in about one-half of adults for four hours with minimal adverse effects similar to those of placebo. Critical Summary Assessment An updated, high-quality of mostly high-quality evidence indicates that a standard dose of acetaminophen relieves postoperative pain safely for four

2010 ADA Center for Evidence-Based Dentistry

90. Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain

Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed (...) acetaminophen as an effective and safe reliever of acutepostoperative pain James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion A single standard dose of acetaminophen relieves moderate to severe postoperative pain in about one-half of adults for four hours with minimal adverse effects similar to those of placebo. Critical Summary Assessment An updated, high-quality of mostly high-quality evidence indicates that a standard dose of acetaminophen relieves postoperative pain safely for four

2010 ADA Center for Evidence-Based Dentistry

91. Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain

Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain Good evidence supports acetaminophen as an effective and safe reliever of acutepostoperative pain ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed (...) acetaminophen as an effective and safe reliever of acutepostoperative pain James Zahrowski DMD, MS, PharmD . Overview Systematic Review Conclusion A single standard dose of acetaminophen relieves moderate to severe postoperative pain in about one-half of adults for four hours with minimal adverse effects similar to those of placebo. Critical Summary Assessment An updated, high-quality of mostly high-quality evidence indicates that a standard dose of acetaminophen relieves postoperative pain safely for four

2010 ADA Center for Evidence-Based Dentistry

92. Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction.

Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take (...) Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. Carlos Flores-Mir DDS, DSc, FRCD(C); Analia Veitz-Keenan DDS . Overview Systematic Review Conclusion A single dose of acetaminophen plus codeine provides clinical useful levels of pain relief in patients with moderate to severe post –operative pain. Critical Summary Assessment This represents an update of a previously published Cochrane Review and it follows general accepted rules about how

2010 ADA Center for Evidence-Based Dentistry

93. Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction.

Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take (...) Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. Carlos Flores-Mir DDS, DSc, FRCD(C); Analia Veitz-Keenan DDS . Overview Systematic Review Conclusion A single dose of acetaminophen plus codeine provides clinical useful levels of pain relief in patients with moderate to severe post –operative pain. Critical Summary Assessment This represents an update of a previously published Cochrane Review and it follows general accepted rules about how

2010 ADA Center for Evidence-Based Dentistry

94. Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction.

Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take (...) Evidence supports the use of a single dose of acetaminophen with codeine for moderate to severe pain reduction. Carlos Flores-Mir DDS, DSc, FRCD(C); Analia Veitz-Keenan DDS . Overview Systematic Review Conclusion A single dose of acetaminophen plus codeine provides clinical useful levels of pain relief in patients with moderate to severe post –operative pain. Critical Summary Assessment This represents an update of a previously published Cochrane Review and it follows general accepted rules about how

2010 ADA Center for Evidence-Based Dentistry

95. Ofirmev (acetaminophen) Injection

Ofirmev (acetaminophen) Injection Drug Approval Package: Ofirmev (acetaminophen) NDA #022450 Drug Approval Package U.S. Food & Drug Administration Search FDA Drug Approval Package - Ofirmev (acetaminophen) Injection, 10 mg/mL Company: Cadence Pharmaceuticals Application No.: 022450 Approval Date: 11/02/2010 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF

2010 FDA - Drug Approval Package

96. Systematic review: NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects

Systematic review: NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects Article Text Therapeutics Systematic

2010 Evidence-Based Nursing

97. Randomised controlled trial: Ibuprofen provides similar pain relief but reduces adverse effects and improves function compared with acetaminophen plus codeine in children with uncomplicated fractures

Randomised controlled trial: Ibuprofen provides similar pain relief but reduces adverse effects and improves function compared with acetaminophen plus codeine in children with uncomplicated fractures Ibuprofen provides similar pain relief but reduces adverse effects and improves function compared with acetaminophen plus codeine in children with uncomplicated fractures | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage (...) similar pain relief but reduces adverse effects and improves function compared with acetaminophen plus codeine in children with uncomplicated fractures Article Text Therapeutics Randomised controlled trial Ibuprofen provides similar pain relief but reduces adverse effects and improves function compared with acetaminophen plus codeine in children with uncomplicated fractures Carie A Braun Carie A Braun College of Saint Benedict/Saint John’s University, 37 College Avenue South, Saint Joseph, MN 56374

2010 Evidence-Based Nursing

98. Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain

Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain Ong CK (...) comparisons assessed was not the most informative approach. Given the poor reporting of the review methodology and concerns about the synthesis the reliability of the authors' conclusions is unclear. Implications of the review for practice and research The authors did not state any implications for practice and further research. Funding AFT Pharmaceuticals. Bibliographic details Ong CK, Seymour RA, Lirk P, Merry AF. Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs

2010 DARE.

99. Acetaminophen use and the risk of asthma in children and adults: a systematic review and metaanalysis (PubMed)

Acetaminophen use and the risk of asthma in children and adults: a systematic review and metaanalysis Epidemiologic studies have identified an increased risk of asthma with acetaminophen use, but the results have been conflicting. We sought to quantify the association between acetaminophen use and the risk of asthma in children and adults.We searched all the major medical databases, including MEDLINE (from 1966 to 2008) and EMBASE (from 1980 to 2008) to identify pertinent articles. All clinical (...) trials and observational studies were considered. For observational studies, we selected those that clearly defined acetaminophen use and asthma diagnosis. Study quality was assessed by two reviewers, and data were extracted into a spreadsheet. A random-effects model was used to combine studies with asthma and wheezing among both children and adults.Thirteen cross-sectional studies, four cohort studies, and two case-control studies comprising 425,140 subjects were included in the review. The pooled

2010 EvidenceUpdates

100. Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review

Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.