Latest & greatest articles for acne

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on acne or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on acne and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Acne treatment and clinical papers

Acne is a common skin condition characterised by whiteheads (or blackheads), pimples and oily skin. It can lead to possible scarring. It is typically caused when hair follicles become inflamed and the sebaceous glands in the skin are overactive. The over production of sebum and a combination of dead skin cells and dirt can clog follicles and pores causing a break out. Acne can affect any age group but it’s more common in adolescents.

There are many ways to treat acne depending on the severity of the case. Treatments include a range of medications such as topical retinoids, antibiotics and in severe cases isotretinoin is prescribed. Research is ongoing to determine the side effects and harms caused by these drugs. Clinical trials and studies are vital to assess treatment.

The Trip Database has an extensive collection of articles on acne ranging from clinical trials, systematic reviews, clinical guidelines and case reports. These can be found via searching the site.

Top results for acne

21. Acne

Acne Evidence Maps - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading

2018 Trip Evidence Maps

22. Safety and effectiveness of amoxicillin in the treatment of inflammatory acne (PubMed)

Safety and effectiveness of amoxicillin in the treatment of inflammatory acne Acne is a common skin disease that predominantly affects teenagers and young adults. Systemic antibiotic therapy, including tetracyclines, macrolides, and trimethoprim-sulfamethoxazole, is indicated in moderate-to-severe inflammatory disease. However, in certain cases, these antibiotics and other commonly prescribed treatments including oral contraceptives, spironolactone, and isotretinoin may be prohibited (...) , especially in cases of pregnancy and drug intolerance. In this retrospective study, we assessed the safety and efficacy of systemic amoxicillin, which has a favorable tolerability profile and compatibility with pregnancy in the treatment of inflammatory acne.

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2018 International journal of women's dermatology

23. Acne vulgaris

Acne vulgaris Acne vulgaris - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Acne vulgaris Last reviewed: February 2019 Last updated: June 2018 Summary Acne may affect any age group, but it is most common in adolescents. Lesions consist of non-inflammatory comedones (whiteheads and blackheads) and inflammatory papules, pustules, nodules, and cysts. Systemic effects may be present with acne fulminans, a rare variant (...) of nodulocystic acne. Treatments include topical retinoids, keratolytics, and antibiotics; severe nodulocystic acne may require oral isotretinoin. Definition Acne vulgaris is a skin disease affecting the pilosebaceous unit. It is characterised by comedones, papules, pustules, nodules, cysts, and/or scarring, primarily on the face and trunk. Clinical manifestations range from mild comedonal acne to severe nodulocystic acne, which can be permanently disfiguring. In addition to the physical lesions, acne can

2018 BMJ Best Practice

24. Acne - Guidelines for Prescribing Topical Treatment

Acne - Guidelines for Prescribing Topical Treatment Acne - Guidelines for Prescribing Topical Treatment - medSask Home - College of Pharmacy and Nutrition - University of Saskatchewan Toggle Menu Search the U of S Search Acne - Guidelines for Prescribing Topical Treatment Acne vulgaris (acne) is the formation of comedones, papules, pustules, nodules, and/or cysts as a result of obstruction and inflammation of pilosebaceous units (hair follicles and their accompanying sebaceous gland (...) want to assess the severity of the patient’s acne: Mild: Some papules or pustules; no nodules or cysts Moderate: Many papules and pustules; few nodules, no cysts Severe: Numerous papules and pustules; many nodules or cysts Rule out the following conditions which have signs / symptoms that may resemble acne vulgaris: Comedones Pustules Papules Nodules Other Open Closed Vulgaris X X X X X Conglobata X XX XX Cysts, abscesses, sinus tracts Fulminans X XX XX Ulcerating cysts Contact pomade use XX X

2018 medSask

25. A review of diagnosis and treatment of acne in adult female patients (PubMed)

A review of diagnosis and treatment of acne in adult female patients This review focuses on the treatment options for adult female patients with acne. Acne in adult female patients may start during adolescence and persist or have an onset in adulthood. Acne has various psychosocial effects that impact patients' quality of life. Treatment of acne in adult women specifically has its challenges due to the considerations of patient preferences, pregnancy, and lactation. Treatments vary widely (...) and treatment should be tailored specifically for each individual woman. We review conventional therapies with high levels of evidence, additional treatments with support from cohort studies and case reports, complementary and/or alternative therapies, and new agents under development for the treatment of patients with acne.

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2017 International journal of women's dermatology

26. How Acne Bumps Cause the Blues: The Influence of Acne Vulgaris on Self-Esteem (PubMed)

How Acne Bumps Cause the Blues: The Influence of Acne Vulgaris on Self-Esteem Acne vulgaris is one of the most common dermatologic complaints. Although dermatologists are skilled at treating acne, invisible psychological scars can be left by the disease. We review 13 articles that examined the effect of acne vulgaris on patients' self-esteem. Overall, these studies demonstrated that acne has a negative effect on self-esteem among patients of all age groups. These effects most strongly affect (...) women and those with severe acne (both subjectively and objectively). Despite the impact on self-esteem, only a minority of patients seek medical treatment, and even fewer seek treatment from a dermatologist. As dermatologists, we are trained in managing acne. We can provide early and effective treatment that improves both the physical and psychological effects. It is up to us to bridge the gap between those suffering from acne and their access to medical treatment.

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2017 International journal of women's dermatology

27. Adalimumab (Humira) - hidradenitis suppurativa (acne inversa)

Adalimumab (Humira) - hidradenitis suppurativa (acne inversa) Final Appraisal Recommendation Advice No: 1217 – July 2017 Adalimumab (Humira ® ) 40 mg solution for injection (pre-filled pen, pre-filled syringe and vial) Limited submission by AbbVie Ltd In reaching the above recommendation AWMSG has taken account of the appraisal documentation prepared by the AWMSG Secretariat (reference number 3371), which includes the AWMSG Secretariat Assessment Report (ASAR), the Preliminary Appraisal (...) – 1217: Adalimumab (Humira ® ) 40 mg solution for injection (pre-filled pen, pre-filled syringe and vial). July 2017 Recommendation of AWMSG Adalimumab (Humira ® ) is recommended as an option for use within NHS Wales for the treatment of active moderate to severe hidradenitis suppurativa (acne inversa) in adolescents from 12 years of age with an inadequate response to conventional systemic hidradenitis suppurativa (HS) therapy. This recommendation applies only in circumstances where the approved

2017 All Wales Medicines Strategy Group

28. Management of severe acne during pregnancy: A case report and review of the literature (PubMed)

Management of severe acne during pregnancy: A case report and review of the literature The treatment of acne during pregnancy is often limited by the potential toxicities that are posed to the fetus by the most common and effective acne therapies. As with all dermatoses during pregnancy, the treatment of acne vulgaris in this population requires a thorough understanding of the risks and benefits that are inherent to each treatment. We report on a case of a 30-year-old pregnant patient (...) with severe acne conglobata who showed significant improvement with a combination treatment of topical modalities, oral metronidazole, and low dose prednisone during pregnancy. We also review the literature and present an approach for the care of these patients.

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2017 International journal of women's dermatology

29. Dienogest/ethinylestradiol can be used for acne after certain other treatments have failed

Dienogest/ethinylestradiol can be used for acne after certain other treatments have failed Dienogest/ethinylestradiol can be used for acne after certain other treatments have failed | European Medicines Agency Search Search Menu Dienogest/ethinylestradiol can be used for acne after certain other treatments have failed Press release 27/01/2017 Use should be limited to women who choose oral contraception The European Medicines Agency (EMA) has recommended that medicines containing a combination (...) of dienogest 2 mg and ethinylestradiol 0.03 mg can continue to be used to treat moderate acne when suitable treatments applied to the skin or antibiotics taken by mouth have not worked. However, these medicines, which are also approved as hormonal contraceptives, should only be used in women who choose oral contraception. Having evaluated the existing data on the effectiveness of the combination in the treatment of acne, EMA's ( ) concluded that there is sufficient evidence to support its use in moderate

2017 European Medicines Agency - EPARs

30. A Review of hormone-based therapies to treat adult acne vulgaris in women (PubMed)

A Review of hormone-based therapies to treat adult acne vulgaris in women Hormone-based therapies including combined oral contraceptive medications and spironolactone are considered effective therapies to treat adult acne in women. Our objective is to provide a concise and comprehensive overview of the types of hormonal therapy that are available to treat acne and comment on their efficacy and safety profiles for clinical practice. A systematic search using the PubMed Database was conducted (...) and spironolactone as adjuvant and monotherapies are safe and effective to treat women with adult acne. However, appropriate clinical examinations, screening, and individual risk assessments particularly for venous thromboembolism risk must be conducted prior to initiating therapy.

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2017 International journal of women's dermatology

31. Spironolactone for the treatment of acne in women, a retrospective study of 110 patients (PubMed)

Spironolactone for the treatment of acne in women, a retrospective study of 110 patients There is limited evidence on the safety and efficacy of spironolactone in the treatment of women with acne. Thus, for many dermatologists spironolactone remains an alternative rather than a mainstay treatment for female patients with acne.An electronic medical records search tool was used to select data from a group of women who received spironolactone to treat acne and were evaluated with the comprehensive (...) acne severity scale (CASS) before treatment and at all follow-up visits. Data points were collected for CASS scores at each follow-up visit, concurrent and previous treatments, and side effects. These data points were used to draw conclusions about the safety and efficacy of spironolactone in this patient population.There were 110 patients that met all eligibility requirements. Of these, 94 patients saw an improvement in their CASS score and 61 patients completely cleared their score to 0

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2017 International journal of women's dermatology

35. Epiduo (adapalene/benzoyl peroxide) 0.3%/2.5% - acne vulgaris

Epiduo (adapalene/benzoyl peroxide) 0.3%/2.5% - acne vulgaris Epiduo® (adapalene/benzoyl peroxide) 0.3%/2.5% × Insert searchphrase to search the website Insert searchphrase to search the website > > > Epiduo® (adapalene/benzoyl peroxide) 0.3%/2.5% Conclusion Epiduo gel is approved for the treatment of acne vulgaris when comedones, several papules and pustules are present. Epiduo contains a combination of the active substances adapalene 3 mg/g (0.3%) and benzoyl peroxide 25 mg/g (2.5 (...) %) – in the following referred to as 0.3% A/BPO. Epiduo is also available in a lower strength containing adapalene 1 mg/g (0.1%) and benzoyl peroxide 25 mg/g (2.5%) – in the following referred to as 0.1% A/BPO. A statistically significant increase in efficacy has been observed in treatment with 0.3% A/BPO of patients with moderate to severe acne compared to inactive vehicle measured by improvement of acne and change in the number of inflammatory and non-inflammatory lesions. After 12 weeks’ treatment with 0.3

2017 Danish Pharmacotherapy Reviews

36. The age-old problem of acne (PubMed)

The age-old problem of acne Acne vulgaris is one of the top three most commonly encountered dermatological problems worldwide in both primary and secondary care. Acne diagnosis and treatment date back to ancient Greek and Egyptian times. This article explores acne through the ages and discusses past theories on etiology and treatment with particular focus on the discovery of retinoids and their impact on women's health.

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2016 International journal of women's dermatology

37. Light therapies for acne. (PubMed)

Light therapies for acne. Acne vulgaris is a very common skin problem that presents with blackheads, whiteheads, and inflamed spots. It frequently results in physical scarring and may cause psychological distress. The use of oral and topical treatments can be limited in some people due to ineffectiveness, inconvenience, poor tolerability or side-effects. Some studies have suggested promising results for light therapies.To explore the effects of light treatment of different wavelengths (...) these searches in July 2016 but these results have not yet been incorporated into the review.We included RCTs of light for treatment of acne vulgaris, regardless of language or publication status.We used standard methodological procedures expected by Cochrane.We included 71 studies, randomising a total of 4211 participants.Most studies were small (median 31 participants) and included participants with mild to moderate acne of both sexes and with a mean age of 20 to 30 years. Light interventions differed

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2016 Cochrane

38. Interventions for acne scars. (PubMed)

Interventions for acne scars. Acne scarring is a frequent complication of acne and resulting scars may negatively impact on an affected person's psychosocial and physical well-being. Although a wide range of interventions have been proposed, there is a lack of high-quality evidence on treatments for acne scars to better inform patients and their healthcare providers about the most effective and safe methods of managing this condition. This review aimed to examine treatments for atrophic (...) and hypertrophic acne scars, but we have concentrated on facial atrophic scarring.To assess the effects of interventions for treating acne scars.We searched the following databases up to November 2015: the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library (2015, Issue 10), MEDLINE (from 1946), EMBASE (from 1974), and LILACS (from 1982). We also searched five trials registers, and checked the reference lists of included studies

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2016 Cochrane

39. Certain Dairy Products Can Negatively Affect Acne Severity in Young Adult Korean and Malaysian Populations

Certain Dairy Products Can Negatively Affect Acne Severity in Young Adult Korean and Malaysian Populations "Certain Dairy Products Can Negatively Affect Acne Severity in Young Ad" by Velika Lotwala < > > > > > Title Author Date of Graduation Summer 8-13-2016 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Saje Davis-Risen, PA-C, MS Second Advisor Annjanette Sommers, PA-C, MS Rights . Abstract Background: Acne vulgaris is a widespread (...) and complex skin condition affecting mainly young adults in developed nations. The correlation between diet and acne has long been debated. Some medical providers routinely advised acne prone patients to refrain from eating excessive sugar and certain foods such as French fries or chocolate however other medical providers dismissed this idea as myth. Recent studies have demonstrated a relationship between certain dairy products and acne severity, particularly in young adult populations. Furthermore

2016 Pacific University EBM Capstone Project

40. Rosacea - acne

Rosacea - acne Rosacea - acne - NICE CKS Clinical Knowledge Summaries Share Rosacea - acne: Summary Acne rosacea is a chronic relapsing skin condition affecting the face, characterized by recurrent episodes of facial flushing, erythema, telangiectasia, papules and pustules. There may be eye symptoms (ocular rosacea), which are usually bilateral. Acne rosacea can be classified into four types (erythematotelangiectatic, papulopustular, phymatous, and ocular) and one variant (granulomatous (...) depression in severe cases), ocular conditions (such as blepharitis, conjunctivitis, meibomian cyst, or keratitis), or rosacea fulminans (a severe form of acne rosacea). Diagnosis is usually made on the basis of one or more clinical features, typically affecting the convexities of the central face, and include: Flushing or transient erythema (pre-rosacea). Persistent erythema (erythematotelangiectatic rosacea). Telangiectasia (erythematotelangiectatic rosacea). Papules and pustules (papulopustular

2016 NICE Clinical Knowledge Summaries