Latest & greatest articles for anastrozole

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Top results for anastrozole

21. Meta-analysis of trials comparing anastrozole and tamoxifen for adjuvant treatment of postmenopausal women with early breast cancer

Meta-analysis of trials comparing anastrozole and tamoxifen for adjuvant treatment of postmenopausal women with early breast cancer Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

22. Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen Al

Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen Al Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex (...) ', Tamoxifen Alone or in Combination) trial Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective - the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen Alone or in Combination) trial Locker GY, Mansel R, Cella D, Dobrez D, Sorensen S, Gandhi SK Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each

2007 NHS Economic Evaluation Database.

23. Cost-effectiveness analysis of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen alone or in combination) trial

Cost-effectiveness analysis of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen alone or in combination) trial Cost-effectiveness analysis of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen alone or in combination) trial Cost-effectiveness analysis (...) of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen alone or in combination) trial Mansel R, Locker G, Fallowfield L, Benedict A, Jones D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment

Full Text available with Trip Pro

2007 NHS Economic Evaluation Database.

24. Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women with breast cancer: upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole

Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women with breast cancer: upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women with breast cancer: upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women (...) with breast cancer: upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole Skedgel C, Rayson D, Dewar R, Younis T Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study examined three adjuvant hormonal

2007 NHS Economic Evaluation Database.

25. Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer

Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer Augustovski F, Pichon Riviere A, Alcaraz A, Bardach A, Garcia Marti S, Lopez A, Glujovsky D, Regueiro A Record Status This is a bibliographic record of a published health technology (...) assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Augustovski F, Pichon Riviere A, Alcaraz A, Bardach A, Garcia Marti S, Lopez A, Glujovsky D, Regueiro A. Aromatase inhibitors (anastrozole, letrozole and examestane) for adjuvant therapy in early breast cancer. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No.63. 2006 Authors' objectives This report is intended

2006 Health Technology Assessment (HTA) Database.

26. Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis

Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis Rocchi A, Verma S Record (...) Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study examined the use of anastrozole (Arimidex) in the adjuvant treatment of hormone receptor-positive (HR+), postmenopausal early breast cancer (BC) patients. Anastrozole was compared

2006 NHS Economic Evaluation Database.

27. Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective

Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective Piskur P, Sonc M, Cufer T, Borstnar S, Mrhar A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains (...) a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study assessed the clinical and economic impact of anastrozole (AN) and tamoxifen for the treatment of postmenopausal women with hormone receptor-positive breast cancer. The authors concluded that AN could be considered a cost-effective strategy from the perspective of the Slovenian health care system. There were a few

2006 NHS Economic Evaluation Database.

28. Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial

Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer: analysis based on the ATAC trial Moeremans K, Annemans L Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The authors compared anastrozole and tamoxifen, both alone and in combination. Dosages and further details were not provided. Type of intervention Treatment. Economic study type Cost-utility analysis. Study population The study population

2006 NHS Economic Evaluation Database.

29. Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer

Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women (...) therapy with aromatase inhibitors or with tamoxifen in postmenopausal women with operable breast cancer. The authors concluded that exemestane after tamoxifen was more cost-effective than anastrozole or letrozole. The quality of the methodology used was satisfactory. Both the results and methods were adequately reported. As there was no head-to-head comparison of the three aromatase inhibitors, caution should be exercised when evaluating which one was the most cost-effective. Type of economic

2006 NHS Economic Evaluation Database.

30. Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis

Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.

31. Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial. (PubMed)

Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial. Tamoxifen has been the standard adjuvant treatment for postmenopausal women with hormone-responsive early breast cancer for more than 20 years. However, the third-generation aromatase inhibitor anastrozole has proven efficacy and tolerability benefits compared with tamoxifen when used as initial adjuvant therapy (...) . We investigate whether women who have received a period of adjuvant tamoxifen would benefit from being switched to anastrozole.We present a combined analysis of data from two prospective, multicentre, randomised, open-label trials with nearly identical inclusion criteria. Postmenopausal women with hormone-sensitive early breast cancer who had completed 2 years' adjuvant oral tamoxifen (20 or 30 mg daily) were randomised to receive 1 mg oral anastrozole (n=1618) or 20 or 30 mg tamoxifen (n=1606

2005 Lancet

32. Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer

Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor (...) -positive breast cancer Hillner B E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of anastrozole (1 mg) as initial adjuvant therapy for women with early-stage estrogen receptor-positive breast cancer. Type of intervention

Full Text available with Trip Pro

2004 NHS Economic Evaluation Database.

33. Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer

Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer Simons W R, Jones D, Buzdar A Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Postmenopausal women with predominantly hormone receptor-positive advanced breast cancer were given anastrozole (1 mg/day) as first-line therapy. The comparator was tamoxifen (20 mg/day). Type of intervention Treatment and secondary prevention. Economic study type Cost-utility

2003 NHS Economic Evaluation Database.

34. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. (PubMed)

Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. In the adjuvant setting, tamoxifen is the established treatment for postmenopausal women with hormone-sensitive breast cancer. However, it is associated with several side-effects including endometrial cancer and thromboembolic disorders. We aimed to compare the safety and efficacy outcomes of tamoxifen (...) with those of anastrozole alone and the combination of anastrozole plus tamoxifen for 5 years.Participants were postmenopausal patients with invasive operable breast cancer who had completed primary therapy and were eligible to receive adjuvant hormonal therapy. The primary endpoints were disease-free survival and occurrence of adverse events. Analysis for efficacy was by intention to treat.9366 patients were recruited, of whom 3125 were randomly assigned anastrozole, 3116 tamoxifen, and 3125 combination

2002 Lancet

35. Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer

Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer Anastrozole: a review of its use in the management of postmenopausal women with advanced breast cancer Wiseman L R, Adkins J C Authors' objectives To examine the use of anastrozole in the management of postmenopausal women with advanced breast cancer. Searching Medical literature published (...) since 1966 on anastrozole was identified using AdisBase, MEDLINE and EMBASE. References also identified from reference lists of published articles. Bibliographic information, including contributory data was also requested from the company developing the drug. Search terms: anastrozole, armidex, ic-d-1033, zd-1033 (all databases), breast cancer, aromatase inhibitor (AdisBase only), 120511-73-1 (MEDLINE and EMBASE only). Searches last updated 1 September 1988. Study selection Study designs

1998 DARE.