Latest & greatest articles for anesthesia

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on anesthesia or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on anesthesia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Anesthesia

Clinical anesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of anesthesia:

  • Local and Regional
  • General
  • Sedation

Anesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of anesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of anesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of anesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in anesthesia and the advancements in anesthesia practise by searching Trip.

Top results for anesthesia

101. Unilateral paravertebral block compared with subarachnoid anesthesia for the management of postoperative pain syndrome after inguinal herniorrhaphy: a randomized controlled clinical trial (PubMed)

Unilateral paravertebral block compared with subarachnoid anesthesia for the management of postoperative pain syndrome after inguinal herniorrhaphy: a randomized controlled clinical trial Inguinal herniorrhaphy is a common surgical procedure. The aim of this investigation was to determine whether unilateral paravertebral block could provide better control of postoperative pain syndrome compared with unilateral subarachnoid block (SAB). A randomized controlled study was conducted using 50 (...) patients with unilateral inguinal hernias. The patients were randomized to receive either paravertebral block (S group) or SAB (C group). Paravertebral block was performed by injecting a total of 20 mL of 0.5% levobupivacaine from T9 to T12 under ultrasound guidance, whereas SAB was performed by injecting 13 mg of 0.5% levobupivacaine at the L3 to L4 level. Data regarding anesthesia, hemodynamic changes, side effects, time spent in the postanesthesia care unit, the Karnofsky Performance Status, acute

2016 EvidenceUpdates

102. Risks Associated With Anesthesia Services During Colonoscopy (PubMed)

Risks Associated With Anesthesia Services During Colonoscopy We aimed to quantify the difference in complications from colonoscopy with vs without anesthesia services.We conducted a prospective cohort study and analyzed administrative claims data from Truven Health Analytics MarketScan Research Databases from 2008 through 2011. We identified 3,168,228 colonoscopy procedures in men and women, aged 40-64 years old. Colonoscopy complications were measured within 30 days, including colonic (ie (...) , perforation, hemorrhage, abdominal pain), anesthesia-associated (ie, pneumonia, infection, complications secondary to anesthesia), and cardiopulmonary outcomes (ie, hypotension, myocardial infarction, stroke), adjusted for age, sex, polypectomy status, Charlson comorbidity score, region, and calendar year.Nationwide, 34.4% of colonoscopies were conducted with anesthesia services. Rates of use varied significantly by region (53% in the Northeast vs 8% in the West; P < .0001). Use of anesthesia service

Full Text available with Trip Pro

2016 EvidenceUpdates

103. Leg Movements During General Anesthesia (PubMed)

Leg Movements During General Anesthesia 28239614 2019 02 26 2330-1619 3 5 2016 Sep-Oct Movement disorders clinical practice Mov Disord Clin Pract Leg Movements During General Anesthesia. 510-512 10.1002/mdc3.12310 Vanegas Nora N Office of the Clinical Director, National Institute of Neurologic Disorders and Stroke, Bethesda, MD, USA; Human Motor Control Section, National Institute of Neurologic Disorders and Stroke, Bethesda, MD, USA. Zaghloul Kareem K Surgical Neurology Branch, National (...) Institute of Neurologic Disorders and Stroke, Bethesda, MD, USA. Hallett Mark M Human Motor Control Section, National Institute of Neurologic Disorders and Stroke, Bethesda, MD, USA. Lungu Codrin C Office of the Clinical Director, National Institute of Neurologic Disorders and Stroke, Bethesda, MD, USA. eng Z99 NS999999 NULL Intramural NIH HHS United States Case Reports 2016 03 24 United States Mov Disord Clin Pract 101630279 2330-1619 Leg Movements Parkinson Disease general anesthesia Conflict

Full Text available with Trip Pro

2016 Movement disorders clinical practice

104. Effectiveness of dexmedetomidine use in general anesthesia to prevent postoperative shivering: a systematic review. (PubMed)

Effectiveness of dexmedetomidine use in general anesthesia to prevent postoperative shivering: a systematic review. Postanesthetic shivering remains a significant source of distress following general anesthesia. Despite numerous studies investigating pharmacologic prophylaxis for postanesthetic shivering, no gold standard medication has been identified. Prophylactic dexmedetomidine administration has been examined as a possible preventative treatment modality for postanesthetic shivering (...) ; however its effectiveness has not been established.The objective of this review was to evaluate the effectiveness of intravenous prophylactic dexmedetomidine for reduction of postanesthetic shivering during the first two hours after general anesthesia. The participants included in this study were adults between 18 and 68 years of age receiving general anesthesia for any surgical procedure. Only participants with American Society of Anesthesiologist physical status I or II were included. Types

2016 JBI database of systematic reviews and implementation reports

105. SCAI/CCAS/SPA Expert Consensus Statement for Anesthesia and Sedation Practice: Recommendations for Patients Undergoing Diagnostic and Therapeutic Procedures in the Pediatric and Congenital Cardiac Catheterization Laboratory

SCAI/CCAS/SPA Expert Consensus Statement for Anesthesia and Sedation Practice: Recommendations for Patients Undergoing Diagnostic and Therapeutic Procedures in the Pediatric and Congenital Cardiac Catheterization Laboratory Core Curriculum SCAI/CCAS/SPA Expert Consensus Statement for Anesthesia and Sedation Practice: Recommendations for Patients Undergoing Diagnostic and Therapeutic Procedures in the Pediatric and Congenital Cardiac Catheterization Laboratory Kirsten C. Odegard, 1 MD (Co-Chair (...) ), Robert Vincent, 2 * MD, FSCAI, FACC (Co-Chair), Rahul Baijal, 3 MD, SuAnne Daves, 4 MD, Robert Gray, 5 MD, Alex Javois, 6 MD, Barry Love, 7 MD, Phil Moore, 8 MD, FSCAI, David Nykanen, 9 MD, FSCAI, Lori Riegger, 10 MD, Scott G. Walker, 11 MD, and Elizabeth C. Wilson 2 MD Current practice of sedation and anesthesia for patients undergoing pediatric congenital cardiac catheterization laboratory (PCCCL) procedures is known to vary among institu- tions,amulti

2016 Society for Cardiovascular Angiography and Interventions

106. Practice Guidelines for Obstetric Anesthesia

Practice Guidelines for Obstetric Anesthesia Practice Guidelines for Obstetric Anesthesia:An Updated Report by the American Society of Anesthesiologists Task Force on Obstetric Anesthesia and the Society for Obstetric Anesthesia and Perinatology* | Anesthesiology | ASA Publications 468217175 ASA Publications Log in to access full content You must be logged in to access this feature. ASA members enjoy complimentary access to ASA publications, as well as a variety of educational resources. Non (...) -ASA Members Login Free Practice Parameter | February 2016 Practice Guidelines for Obstetric Anesthesia: An Updated Report by the American Society of Anesthesiologists Task Force on Obstetric Anesthesia and the Society for Obstetric Anesthesia and Perinatology* Author Notes This article is featured in “This Month in Anesthesiology,” page 1A. This article is featured in “This Month in Anesthesiology,” page 1A. Supplemental Digital Content is available for this article. Direct URL citations appear

Full Text available with Trip Pro

2016 American Society of Anesthesiologists

107. The Second American Society of Regional Anesthesia and Pain Medicine Evidence-Based Medicine Assessment of Ultrasound-Guided Regional Anesthesia

The Second American Society of Regional Anesthesia and Pain Medicine Evidence-Based Medicine Assessment of Ultrasound-Guided Regional Anesthesia The Second American Society of Regional Anesthesia and Pain... : Regional Anesthesia and Pain Medicine You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Login No user account? Lippincott Journals Subscribers , use your username or email along with your password to log in. Remember me (...) refer to our Privacy Policy. Toggle navigation Articles & Issues Collections For Authors Journal Info > > The Second American Society of Regional Anesthesia and Pain... If you're not a subscriber, you can: You can read the full text of this article if you: Institutional members Email to a Colleague Colleague's E-mail is Invalid Your Name: (optional) Your Email: Colleague's Email: Separate multiple e-mails with a (;). Message: Thought you might appreciate this item(s) I saw at Regional Anesthesia

2016 American Society of Regional Anesthesia and Pain Medicine

108. Guidelines for the use of local anesthesia in office-based dermatologic surgery

Guidelines for the use of local anesthesia in office-based dermatologic surgery Guidelines for the use of local anesthesia in office-based dermatologic surgery - Journal of the American Academy of Dermatology Email/Username: Password: Remember me Search JAAD & JAAD Case Reports Search Terms Search within Search Access provided by Volume 74, Issue 6, Pages 1201–1219 Guidelines for the use of local anesthesia in office-based dermatologic surgery Work Group:, x David J. Kouba Affiliations Toledo (...) anesthesia for dermatologic office-based procedures. In addition to recommendations for dermatologists, this guideline also takes into account patient preferences while optimizing their safety and quality of care. The clinical recommendations presented here are based on the best evidence available as well as expert opinion. Key words: , , , , , , , , , , , , Disclaimer Adherence to these guidelines will not ensure successful treatment in every situation. Furthermore, these guidelines should

2016 American Academy of Dermatology

109. [Neuromuscular monitoring during anesthesia.]. (PubMed)

[Neuromuscular monitoring during anesthesia.]. Muscle relaxants are very important in anesthetic practice but must be used with great care. Studies have shown that 17-40% of patients in postanesthesia care units (PACU) have residual muscle weakness. The purpose of this study was to evaluate whether the use of neuromuscular monitors during anesthesia could reduce the incidence of muscle weakness in the postoperative period.Eighty patients operated for laparoscopic cholecystectomy or lumbal disc (...) prolapse given muscle relaxants during anesthesia were studied, randomly allocated to four groups. Fourty of these patients were monitored with neuromuscular monitor (TOF-guard") during anesthesia and the set point was a TOF-ratio of at least 70% before extubating the patients. Fourty patients were monitored by usual clinical signs (spontaneus breathing, cough and muscle movement). Twenty patients in each group were given vecuronium as muscle relaxant and 20 patients recieved pancuronium, again

2015 Laeknabladid

110. Prophylactic ondansetron for prevention of maternal hypotension following spinal anesthesia in women undergoing cesarean section: a systematic review protocol. (PubMed)

Prophylactic ondansetron for prevention of maternal hypotension following spinal anesthesia in women undergoing cesarean section: a systematic review protocol. 26470663 2018 06 25 2202-4433 13 9 2015 Sep JBI database of systematic reviews and implementation reports JBI Database System Rev Implement Rep Prophylactic ondansetron for prevention of maternal hypotension following spinal anesthesia in women undergoing cesarean section: a systematic review protocol. 84-94 10.11124/jbisrir-2015-2373

2015 JBI database of systematic reviews and implementation reports

111. Effectiveness of positive end-expiratory pressure, decreased fraction of inspired oxygen and vital capacity recruitment maneuver in the prevention of pulmonary atelectasis in patients undergoing general anesthesia: a systematic review. (PubMed)

Effectiveness of positive end-expiratory pressure, decreased fraction of inspired oxygen and vital capacity recruitment maneuver in the prevention of pulmonary atelectasis in patients undergoing general anesthesia: a systematic review. General anesthesia causes impairment of gas exchange in the lungs that results in decreased oxygenation of the blood; atelectasis is the principle cause of this impaired gas exchange. Anesthesia delivery varies between providers and there is no standard practice (...) to decrease the incidence of postoperative atelectasis.To assess the effectiveness of three identified interventions, either individually or combined, in the development of postoperative pulmonary atelectasis in patients undergoing general anesthesia.The review considered participants over 18 years for inclusion. The American Society of Anesthesiologists classification of subjects was I, II or III. Participants underwent a variety of surgical procedures during which general anesthesia was administered

2015 JBI database of systematic reviews and implementation reports

112. Effectiveness of dexmedetomidine use in general anesthesia to prevent postoperative shivering: a systematic review protocol. (PubMed)

Effectiveness of dexmedetomidine use in general anesthesia to prevent postoperative shivering: a systematic review protocol. 26447032 2016 04 14 2018 12 02 2202-4433 13 2 2015 Mar 12 JBI database of systematic reviews and implementation reports JBI Database System Rev Implement Rep Effectiveness of dexmedetomidine use in general anesthesia to prevent postoperative shivering: a systematic review protocol. 37-48 10.11124/jbisrir-2015-1902 Hoffman Jeffrey J Texas Christian University, Fort Worth (...) Dexmedetomidine IM Adrenergic alpha-2 Receptor Agonists therapeutic use Anesthesia, General Dexmedetomidine therapeutic use Humans Postoperative Period Shivering drug effects Systematic Reviews as Topic Dexmedetomidine anaesthesia anesthesia postanesthetic postoperative shivering 2014 08 24 2014 12 19 2014 11 07 2015 10 9 6 0 2015 10 9 6 0 2016 4 15 6 0 epublish 26447032 10.11124/jbisrir-2015-1902

2015 JBI database of systematic reviews and implementation reports

113. Effectiveness of ondansetron as an adjunct to lidocaine intravenous regional anesthesia on tourniquet pain and postoperative pain in patients undergoing elective hand surgery: a systematic review protocol. (PubMed)

Effectiveness of ondansetron as an adjunct to lidocaine intravenous regional anesthesia on tourniquet pain and postoperative pain in patients undergoing elective hand surgery: a systematic review protocol. The objective of this quantitative systematic review is to determine the effects of ondansetron as an adjunct to lidocaine on the tourniquet pain and postoperative pain of American Society of Anesthesiologists (ASA) class 1 or 2 adult patients undergoing elective hand surgery with intravenous (...) regional anesthesia.Both injury and deformity of the upper extremity can result in dysfunction to nerves, tendons and bones which can lead to disability and pain. Hand injuries and deformities encompass an area of upper extremity surgery, wherein isolation and accessibility to peripheral nerves allows for a wide range of anesthesia techniques. Common hand surgeries include carpal tunnel or trigger finger release, Dupuytren's contracture fasciectomy, tendon repair, and ganglion cyst removal. According

2015 JBI database of systematic reviews and implementation reports

114. Multimodal Analgesia in Total Knee Arthroplasty: A Randomized, Double-Blind, Controlled Trial on Additional Efficacy of Periarticular Anesthesia (PubMed)

Multimodal Analgesia in Total Knee Arthroplasty: A Randomized, Double-Blind, Controlled Trial on Additional Efficacy of Periarticular Anesthesia Pain management is a main determinant of functional recovery after total knee arthroplasty (TKA). We performed a randomized, controlled, double blind study to evaluate additive efficacy of periarticular anesthesia in patients undergoing TKA in reducing post-operative pain, operated limb edema and improving post-operative mobility. Patients were (...) randomly assigned to study or control group; all subjects received the same analgesic protocol; before wound closure, the study group received also a periarticular anesthesia (ropivacaine 1% 20 mL). The results show no statistical differences in any of the variable evaluated. Our data suggest that additive periarticular anesthetic protocol with ropivacaine 1% 20 mL is not superior to oral and intravenous analgesia alone in patients undergoing TKA, regarding post-operative pain control, operated limb

2015 EvidenceUpdates

115. Less Pain 1 Year After TEP Compared with Lichtenstein Using Local Anesthesia: Data from a Randomized Controlled Clinical Trial (PubMed)

Less Pain 1 Year After TEP Compared with Lichtenstein Using Local Anesthesia: Data from a Randomized Controlled Clinical Trial The aim was to compare long-term postoperative pain after inguinal hernia surgery using 2 techniques that have shown favorable long-term outcome in previous randomized studies: Lichtenstein using local anesthesia (LLA) and endoscopic total extra-peritoneal repair (TEP) under general anesthesia.Patients often experience pain after inguinal hernia surgery. These 2 methods (...) in their optimal state have not yet been sufficiently compared.A randomized controlled trial was conducted to detect any difference in long-term postoperative inguinal pain. Altogether 384 patients were randomized and operated using either TEP under general anesthesia (n = 193) or LLA (n = 191). One year postoperatively, patients were examined by an independent surgeon and requested to complete the Inguinal Pain Questionnaire (IPQ), a validated questionnaire for the assessment of postoperative inguinal

2015 EvidenceUpdates

116. Comparison Between Ultrasonography-Guided Popliteal Sciatic Nerve Block and Spinal Anesthesia for Hallux Valgus Repair (PubMed)

Comparison Between Ultrasonography-Guided Popliteal Sciatic Nerve Block and Spinal Anesthesia for Hallux Valgus Repair We aimed to compare the efficacy, postoperative pain scores, adverse effects, additional analgesic requirements, and patient satisfaction scores of ultrasonography-guided sciatic nerve block by popliteal approach with spinal anesthesia for hallux valgus correction surgery.Sixty patients scheduled for hallux valgus correction surgery were enrolled in this prospective randomized (...) study. Unilateral spinal block was performed on patients in the spinal anesthesia group. Popliteal block group patients received popliteal sciatic nerve block with guidance by both nerve stimulator and ultrasonography. Durations of anesthetic and operative interventions and time until the initiation of surgery were recorded for both groups. Pain magnitude of the patients at the 2nd, 4th, 6th, 12th, and 24th hours following anesthetic interventions were assessed with a visual analog scale (VAS

Full Text available with Trip Pro

2015 EvidenceUpdates

117. Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial (PubMed)

Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial Patients undergoing emergency procedures under general anesthesia have impaired gastric emptying and are at high risk for aspiration of gastric contents. Erythromycin has strong gastric prokinetic properties.To evaluate the efficacy of erythromycin lactobionate in gastric emptying in patients undergoing emergency surgery.The Erythro-Emerge trial was a single-center (...) , randomized, double-blinded, placebo-controlled clinical trial in patients undergoing emergency surgery under general anesthesia at Geneva University Hospitals. We included 132 patients from March 25, 2009, through April 10, 2013, and all patients completed the study. Randomization was stratified for trauma and nontrauma procedures. The randomization code was opened on April 23, 2013, and analyses were performed through July 26, 2013. We performed an intention-to-treat analysis.Patients were randomized

Full Text available with Trip Pro

2015 EvidenceUpdates

118. Perioperative local infiltration anesthesia with ropivacaine has no effect on postoperative pain after total hip arthroplasty (PubMed)

Perioperative local infiltration anesthesia with ropivacaine has no effect on postoperative pain after total hip arthroplasty The local infiltration analgesia (LIA) technique has been widely used to reduce opioid requirements and to improve postoperative mobilization following total hip arthroplasty (THA). However, the evidence for the efficacy of LIA in THA is not yet clear. We determined whether single-shot LIA in addition to a multimodal analgesic regimen would reduce acute postoperative (...) pain and opioid requirements after THA.116 patients undergoing primary THA under spinal anesthesia were included in this randomized, double-blind, placebo-controlled trial. All patients received oral opioid-sparing multimodal analgesia: etoricoxib, acetaminophen, and glucocorticoid. The patients were randomized to receive either 150 mL ropivacaine (2 mg/mL) and 0.5 mL epinephrine (1 mg/mL) or 150 mL 0.9% saline. Rescue analgesic consisted of morphine and oxycodone as needed. The primary endpoint

Full Text available with Trip Pro

2015 EvidenceUpdates

119. Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered

Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered UTCAT2881, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered Clinical Question Are lasers less likely than rotary burs to cause a patient (...) pain during caries excavation when the patient has not received anesthesia? Clinical Bottom Line For patients in need of caries excavation who will not allow or have contraindications to the use of local anesthetic, Er:YAG lasers are less likely than rotary burs to cause a patient discomfort. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Dommisch/2008 26 adults with 102 carious lesions Randomized

2015 UTHSCSA Dental School CAT Library

120. Effect of Sedative Premedication on Patient Experience After General Anesthesia: A Randomized Clinical Trial. (PubMed)

Effect of Sedative Premedication on Patient Experience After General Anesthesia: A Randomized Clinical Trial. Sedative premedication is widely administered before surgery, but little clinical evidence supports its use.To assess the efficacy of sedative premedication on perioperative patient experience.A randomized clinical trial, the PremedX study, enrolled 1062 adult patients who were younger than 70 years and had been scheduled for various elective surgeries under general anesthesia at 5 (...) minutes) for the placebo group (P < .001) and the rate of early cognitive recovery was 51% (95% CI, 45%-56%), 71% (95% CI, 66%-76%), and 64% (95% CI, 59%-69%), respectively (P < .001).Among patients undergoing elective surgery under general anesthesia, sedative premedication with lorazepam compared with placebo or no premedication did not improve the self-reported patient experience the day after surgery, but was associated with modestly prolonged time to extubation and a lower rate of early cognitive

Full Text available with Trip Pro

2015 JAMA