Latest & greatest articles for babies

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Top results for babies

41. Estimating neonatal length of stay for babies born very preterm (Full text)

Estimating neonatal length of stay for babies born very preterm To predict length of stay in neonatal care for all admissions of very preterm singleton babies.All neonatal units in England.Singleton babies born at 24-31 weeks gestational age from 2011 to 2014. Data were extracted from the National Neonatal Research Database.Competing risks methods were used to investigate the competing outcomes of death in neonatal care or discharge from the neonatal unit. The occurrence of one event prevents (...) the other from occurring. This approach can be used to estimate the percentage of babies alive, or who have been discharged, over time.A total of 20 571 very preterm babies were included. In the competing risks model, gestational age was adjusted for as a time-varying covariate, allowing the difference between weeks of gestational age to vary over time. The predicted percentage of death or discharge from the neonatal unit were estimated and presented graphically by week of gestational age. From

2018 EvidenceUpdates PubMed

42. Association between use of systematic reviews and national policy recommendations on screening newborn babies for rare diseases: systematic review and meta-analysis. (Full text)

Association between use of systematic reviews and national policy recommendations on screening newborn babies for rare diseases: systematic review and meta-analysis. To understand whether international differences in recommendations of whether to screen for rare diseases using the newborn blood spot test might in part be explained by use of systematic review methods.Systematic review and meta-analysis.Website searches of 26 national screening organisations.Journal articles, papers, legal

2018 BMJ PubMed

43. Mother and Baby Units matter: improved outcomes for both (Full text)

Mother and Baby Units matter: improved outcomes for both Mother and Baby Units (MBUs) are usually preferred by patients and clinicians. Current provision is limited, although expansion is in progress. To ensure successful investment in services, outcome measurement is vital.To describe maternal outcomes, mother-infant outcomes and their relationship in one MBU.Paired maternal Brief Psychiatric Rating Scale (BPRS) scores, Health of the Nation Outcome Scales (HoNOS) scores and Crittenden CARE (...) -Index (CCI) mother-infant interaction data were collected at admission and discharge.There were significant improvements in BPRS (n = 152), HoNOS (n = 141) and CCI (n = 62) scores across diagnostic groups. Maternal BPRS scores and mother-infant interaction scores were unrelated. Improvement in maternal HoNOS scores was associated with improved maternal sensitivity and reduction in maternal unresponsiveness and infant passiveness.Positive outcomes were achieved for mothers and babies across all

2018 BJPsych open PubMed

44. Placing wet gauze on babies’ tummies speeds up urine collection

Placing wet gauze on babies’ tummies speeds up urine collection Placing wet gauze on babies’ tummies speeds up urine collection Discover Portal Discover Portal Placing wet gauze on babies’ tummies speeds up urine collection Published on 17 October 2017 doi: Almost a third of infants managed to urinate within five minutes after a painless, cheap technique that stimulates the skin, compared with 12% of infants observed only, as is standard practice. The ‘Quick-Wee’ method involved rubbing (...) the babies’ abdomens gently with gauze soaked in cold saline before collecting urine. This trial was carried out with 354 babies aged one to 11 months in one Australian paediatrics emergency room. NICE guidelines recommend non-invasive ‘clean catch’ collection if possible but this can be difficult, especially in young children. They estimate that 20 minutes of staff time can be needed to obtain a sample. Hospital paediatrics settings and primary care may want to try this promising, cheap and safe

2018 NIHR Dissemination Centre

45. Assisted reproduction using donated eggs has higher risk of complications for mothers and babies

Assisted reproduction using donated eggs has higher risk of complications for mothers and babies Assisted reproduction using donated eggs has higher risk of complications for mothers and babies Discover Portal Discover Portal Assisted reproduction using donated eggs has higher risk of complications for mothers and babies Published on 13 December 2016 doi: Assisted reproduction with donated eggs carries about double the chance of some risks for mothers and babies when compared to pregnancies (...) involving donated eggs was in 1984. Since then, several studies have reported that high blood pressure during pregnancy, including pre-eclampsia, is more common in women who receive IVF using donor eggs. Pre-eclampsia is a major cause of maternal illness and mortality. Other studies have suggested that babies of egg donation pregnancies may also have poorer outcomes. This systematic review aimed to pool the results of these observational studies, to get a clearer picture of the potential risks

2018 NIHR Dissemination Centre

46. Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success

Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success Discover Portal Discover Portal Supplementary feeding of preterm babies by cup rather than bottle helps breastfeeding success Published on 13 December 2016 doi: For women who chose to breastfeed their preterm baby, supplementary feeds with a cup, compared with a bottle, led to improved breastfeeding rates (...) at discharge and up to six months later. Preterm babies who are transitioning from being tube fed to breastfeeds have traditionally been given bottle feeds (of breast milk or formula) to supplement breastfeeding if the mother is unavailable or if additional feeds are thought necessary. This small Cochrane review found evidence that babies were more likely to be fully breastfed or to have at least some breastfeeds when cup feeds were used to supplement breastfeeding. In contrast to a 2008 review on the same

2018 NIHR Dissemination Centre

47. Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously

Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously Discover Portal Discover Portal Fewer large babies are born to pregnant woman with type 1 diabetes if their glucose was monitored continuously Published on 12 December 2017 doi: Pregnant women with type 1 diabetes who used a continuous glucose monitoring system were half (...) as likely to have a large baby compared with those using standard finger prick blood glucose measurements. Only 15% of infants needed intensive care admissions due to low blood glucose in the continuous glucose monitoring group, compared with 28% born to mothers in the standard finger prick control group. Pregnant women using continuous monitoring spent 7% more time in the target glucose range than those on standard measurements. However, their HbA1c levels, which indicate diabetic control over 12 weeks

2018 NIHR Dissemination Centre

48. Induction of labour may be considered in pregnant women with a large baby

Induction of labour may be considered in pregnant women with a large baby Induction of labour may be considered in pregnant women with a large baby Discover Portal Discover Portal Induction of labour may be considered in pregnant women with a large baby Published on 20 June 2017 doi: Induction of labour does not increase the risk of caesarean delivery in pregnant women with a larger than average baby. This is based on a review of four trials of 1190 women with a suspected large baby who were (...) allocated either to have labour induced from 38 weeks or to watchful waiting. Induction did not increase the risk of most negative outcomes for the baby, such as bleeding in the brain, or mother, such as major tearing. However, these outcomes are rare, so a larger number of women would need to be studied to be confident in these findings. When mothers were not induced babies were larger and born about a week later than if they were induced. They did suffer from more fractures, which can

2018 NIHR Dissemination Centre

49. Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk

Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk Discover Portal Discover Portal Fortified donor breast milk led to similar development for very-low-birthweight babies compared with formula milk Published on 18 April 2017 doi: Providing very-low-birthweight babies with fortified human donor breast milk made (...) no difference to their developmental neurological outcomes at 18 months compared with giving formula. This randomised controlled trial looked at 363 babies with birth weights of less than 1500g in neonatal intensive care units in Canada. When the mother’s own milk supply was limited, the babies were given either nutrient-enriched donor breast milk or formula developed for premature babies. There was no difference in their understanding, language, or ability to manipulate objects at 18 months. This finding

2018 NIHR Dissemination Centre

50. Skin-to-skin contact improves breastfeeding of healthy babies

Skin-to-skin contact improves breastfeeding of healthy babies Skin-to-skin contact improves breastfeeding of healthy babies Discover Portal Discover Portal Skin-to-skin contact improves breastfeeding of healthy babies Published on 28 March 2017 doi: Early skin-to-skin contact improves breastfeeding of healthy full-term babies. Skin-to-skin contact is the direct contact between a naked baby and the mother’s bare chest. It can occur before or after the baby is cleaned following birth. This review (...) found that about a quarter more women who have this contact with their babies are still breastfeeding at one to four months after birth compared with those who don’t. The evidence that skin-to-skin contact may also help to stabilise the baby’s heart and breathing rates and blood sugar levels after birth was based on fewer trials and less strong. These findings support UK good practice to promote immediate skin-to-skin contact after birth to improve breastfeeding rates. It remains one

2018 NIHR Dissemination Centre

51. Antenatal corticosteroids reduce breathing problems in late preterm babies

Antenatal corticosteroids reduce breathing problems in late preterm babies Antenatal corticosteroids reduce breathing problems in late preterm babies Discover Portal Discover Portal Antenatal corticosteroids reduce breathing problems in late preterm babies Published on 21 February 2017 doi: Giving corticosteroids to women at risk of preterm birth at 34 weeks of pregnancy or later reduced the risk of severe breathing problems in the baby after birth from 1.9% to 1.1%. Steroids also reduced (...) the risk for babies born by planned caesarean section after 37 weeks (so not premature). Steroids are known to be beneficial if given to pregnant women at risk of preterm birth before 34 weeks and are already advised for babies born by caesarean section. This meta-analysis of six large trials provides new evidence that steroids might also benefit premature babies born after the 34th week. However, the review also found steroids increased the risk of low blood sugar in the new-born, which would need

2018 NIHR Dissemination Centre

52. Breastfeeding reduces crying during baby immunisation

Breastfeeding reduces crying during baby immunisation Breastfeeding reduces crying during baby immunisation Discover Portal Discover Portal Breastfeeding reduces crying during baby immunisation Published on 21 February 2017 doi: Babies who were breastfed before and during routine childhood immunisations cried on average for 38 seconds less and had lower pain scores compared to babies not breastfed. This evidence review used data from 10 trials, with results for 1,066 babies, mostly between one (...) and six months old, following their normal immunisation schedule. Immunisation levels in England are below recommended levels and falling. Pain from injections causes distress to babies and parents, and may put parents off bringing their children for immunisation or finishing the course of treatment over a year. This is the first review to focus studies of breastfeeding for any painful procedure for older babies. The only trials found related to immunisations, and none was on other procedures

2018 NIHR Dissemination Centre

53. Preterm babies do not benefit from a new IV feeding regimen

Preterm babies do not benefit from a new IV feeding regimen Preterm babies do not benefit from a new IV feeding regimen Discover Portal Discover Portal Preterm babies do not benefit from a new IV feeding regimen Published on 14 July 2016 doi: Intravenous feeding solutions with a higher dose of amino acids or solutions containing fish oils do not provide better outcomes for preterm infants. Many preterm babies can’t feed normally for the first few weeks after birth so they are given a mixture (...) acids or emulsions containing fish oils are beneficial compared to a standard approach, where the dose of amino acids is slowly increased and soya oil is used. Share your views on the research. Why was this study needed? Each year about 8000 extremely preterm infants, born before 31 weeks of gestation, are born in the UK. Until they are able to tolerate milk feeds most of these babies receive intravenous feeding which starts at a variable time after birth and is usually increased slowly, though

2018 NIHR Dissemination Centre

54. A trial of probiotics for treating sepsis in very premature babies poses more questions than it answers

A trial of probiotics for treating sepsis in very premature babies poses more questions than it answers A trial of probiotics for treating sepsis in very premature babies poses more questions than it answers Discover Portal Discover Portal A trial of probiotics for treating sepsis in very premature babies poses more questions than it answers Published on 23 December 2015 doi: Contrary to a previous review of trials, this large, NIHR-funded trial found that probiotic treatment did not prevent (...) two common life-threatening conditions in very premature babies. The conditions were necrotising enterocolitis, which is a severe gut inflammation/infection that can result in the death of intestinal tissue, and sepsis (blood poisoning) from bacteria that have crossed from the gut into the bloodstream. This trial used a single strain of a harmless bacterium, known as a “probiotic”, prepared to high quality standards fit for medicines, and chosen because it is commonly used in dietary supplements

2018 NIHR Dissemination Centre

55. Kangaroo mother care may boost the survival of newborn, premature babies

Kangaroo mother care may boost the survival of newborn, premature babies Kangaroo mother care may boost the survival of newborn, premature babies Discover Portal Discover Portal Kangaroo mother care may boost the survival of newborn, premature babies Published on 23 February 2016 doi: Kangaroo mother care reduced the death rate of newborns by around a quarter compared with conventional care, according to a review of studies from around the world. Other positive outcomes included lower risk (...) of neonatal sepsis, hypothermia, hypoglycaemia, hospital readmission and higher exclusive breast feeding rates. Kangaroo care definitions vary by study, but typically promote mother and baby skin-to-skin contact, sometimes in combination with other elements like promoting breast feeding, and early supported discharge from hospital. Most of the studies in this review looked at premature babies born before 37 weeks and some studies were in low or middle income countries. Prolonged skin-to-skin contact

2018 NIHR Dissemination Centre

56. Inhaling a saline mist did not reduce the time in hospital for babies with bronchiolitis

Inhaling a saline mist did not reduce the time in hospital for babies with bronchiolitis Inhaling a saline mist did not reduce the time in hospital for babies with bronchiolitis Discover Portal Discover Portal Inhaling a saline mist did not reduce the time in hospital for babies with bronchiolitis Published on 28 October 2015 doi: In this NIHR-funded trial babies with a viral chest infection (acute bronchiolitis) were treated either with a strong saline mist (nebulised 3% hypertonic sodium (...) chloride) with standard care or standard care alone. The stronger than usual, hypertonic saline mist had no effect on the time it took for babies to be ready for discharge, nor did the trial demonstrate any other benefit from its use. The treatment itself caused some minor side effects in a few babies, such as excessive coughing and a fall in blood oxygen levels. It was also not cost-effective at usual NHS thresholds. The results of the trial should be directly relevant to the UK context. The authors

2018 NIHR Dissemination Centre

57. Heated, humidified high-flow oxygen therapy may be a useful alternative to other forms of respiratory support for preterm babies

Heated, humidified high-flow oxygen therapy may be a useful alternative to other forms of respiratory support for preterm babies Heated, humidified high-flow oxygen therapy may be a useful alternative to other forms of respiratory support for preterm babies Discover Portal Discover Portal Heated, humidified high-flow oxygen therapy may be a useful alternative to other forms of respiratory support for preterm babies Published on 7 December 2015 doi: This review found that heated, humidified high (...) -flow oxygen therapy by nose was a safe and effective alternative to other non-invasive methods for supporting breathing for preterm babies. It was less likely to cause nasal injury compared with other methods that used nose tubes. Oxygen therapy is commonly used as a form of breathing support for preterm babies with respiratory distress syndrome, a common complication of premature delivery that makes it hard for a baby to breathe. High-flow therapy may therefore be used instead of mechanical

2018 NIHR Dissemination Centre

58. Inducing labour in older women having their first baby does not increase the chance of caesarean delivery

Inducing labour in older women having their first baby does not increase the chance of caesarean delivery Inducing labour in older women having their first baby does not increase the chance of caesarean delivery Discover Portal Discover Portal Inducing labour in older women having their first baby does not increase the chance of caesarean delivery Published on 26 April 2016 doi: Planning to artificially start labour for older women, pregnant with their first child, in the 39th week of pregnancy (...) does not affect the chance of having a caesarean delivery, according to a new trial funded by NIHR. Older women having a first baby have a higher risk of stillbirth and other complications than younger mothers and inducing labour at or before the due date is thought to reduce this risk. However, there have been fears that inducing labour may raise the risk of a caesarean delivery. This study found that women aged 35 or over having their first child and who were induced at 39 weeks had no higher

2018 NIHR Dissemination Centre

59. High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies

High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies Discover Portal Discover Portal High-flow oxygen therapy may be a useful alternative to other forms of breathing support for preterm babies Published on 17 May 2016 doi: This systematic review found high-flow oxygen delivered by nose was as effective and safe as other non-invasive (...) methods of breathing support for preterm babies. The numbers of treatment failures, deaths and rates of chronic lung disease were similar. Most studies were of high-flow oxygen for babies after tubes used for ventilation had been removed. For these babies use of high-flow techniques were less likely to cause nasal damage or a collapsed lung than other non-invasive methods. High-flow oxygen therapy delivers gas through thin tubes that sit just inside each nostril, whereas the most common non-invasive

2018 NIHR Dissemination Centre

60. A new method for monitoring baby’s heart beat during labour probably not justified

A new method for monitoring baby’s heart beat during labour probably not justified A new method for monitoring baby’s heart beat during labour probably not justified Discover Portal Discover Portal A new method for monitoring baby’s heart beat during labour probably not justified Published on 1 March 2016 doi: A new way of monitoring a baby’s distress during labour, called ST waveform analysis, did not improve outcomes for the baby or reduce the likelihood of a caesarean section compared (...) to current practice. Although monitoring of babies’ heartbeats during labour is common practice in the UK, additional ST analysis is not commonly used and on the basis of this evidence probably should not be promoted for routine use yet. The outcomes measured in this review included death of the baby before or after birth, fits and brain damage from low oxygen levels. Finding babies at risk of these rare events is important as urgent delivery may save the baby. However if there is a role for ST analysis

2018 NIHR Dissemination Centre