Latest & greatest articles for cardiac arrest

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on cardiac arrest or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on cardiac arrest and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for cardiac arrest

41. Beta-blockade for the treatment of cardiac arrest due to ventricular fibrillation or pulseless ventricular tachycardia: a systematic review and meta-analysis

Beta-blockade for the treatment of cardiac arrest due to ventricular fibrillation or pulseless ventricular tachycardia: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content (...) ruler software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac

2019 PROSPERO

42. Systematic review and meta-analysis of criteria to diagnose cardiac arrest in dispatch centres

Systematic review and meta-analysis of criteria to diagnose cardiac arrest in dispatch centres Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external (...) or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac ischemia, duration of ischemia and duration

2019 PROSPERO

43. CPR quality and improvement methods among emergency medical service providers attending out-of-hospital cardiac arrest (OHCA): protocol for a systematic review

CPR quality and improvement methods among emergency medical service providers attending out-of-hospital cardiac arrest (OHCA): protocol for a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content (...) ruler software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac

2019 PROSPERO

44. Efficacy of the cooling method for targeted temperature management in post-cardiac arrest patients: a systematic review and meta-analysis

Efficacy of the cooling method for targeted temperature management in post-cardiac arrest patients: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration (...) software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac ischemia

2019 PROSPERO

45. Oxygen's effect on mortality and pulmonary hypertension with out-of-hospital cardiac arrest patients: a systematic review and meta-analysis

Oxygen's effect on mortality and pulmonary hypertension with out-of-hospital cardiac arrest patients: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration (...) software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac ischemia

2019 PROSPERO

46. Diagnostic performance of diffusion weighted imaging for predicting neurologic outcome in post-cardiac arrest patients: A systematic review and meta-analysis

Diagnostic performance of diffusion weighted imaging for predicting neurologic outcome in post-cardiac arrest patients: A systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content (...) ruler software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac

2019 PROSPERO

47. Bystander versus no bystander cardiopulmonary resuscitation for pediatric out of hospital cardiac arrest

Bystander versus no bystander cardiopulmonary resuscitation for pediatric out of hospital cardiac arrest Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files (...) or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac ischemia, duration of ischemia and duration

2019 PROSPERO

48. Coronary angiography after cardiac arrest without ST-segment elevation: a meta-analysis of randomized trials

Coronary angiography after cardiac arrest without ST-segment elevation: a meta-analysis of randomized trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files (...) or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac ischemia, duration of ischemia and duration

2019 PROSPERO

49. Early coronary angiography and percutaneous coronary intervention for out of hospital cardiac arrest survivors without ST-segment elevation: a systematic review and meta-analysis

Early coronary angiography and percutaneous coronary intervention for out of hospital cardiac arrest survivors without ST-segment elevation: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility (...) , method of induction of cardiac ischemia, duration of ischemia and duration of reperfusion (if applicable). ">Data to be extracted: animal model Example: Dose, timing of administration, frequency of administration, route of administration, vehicle. ">Data to be extracted: intervention of interest Example: Serum creatinine; continuous; umol/L (may be recalculated from mg/dL). ">Data to be extracted: primary outcome(s) Example: Blood urea nitrogen; continuous; mmol/L (may be recalculated from mg/dL

2019 PROSPERO

50. Perioperative and anesthesia-related cardiac arrest and mortality rates in a developing country: systematic review with proportion meta-analysis

Perioperative and anesthesia-related cardiac arrest and mortality rates in a developing country: systematic review with proportion meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content (...) ruler software. In case data are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac

2019 PROSPERO

51. Prediction of neurological outcome in comatose survivors of cardiac arrest: a systematic review and meta-analysis

Prediction of neurological outcome in comatose survivors of cardiac arrest: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated (...) are not reported or unclear, we will attempt to contact authors by e-mail (max. 2 attempts). In case an outcome is measured at multiple time points, data from the time point where efficacy is highest will be included. ">Methods for data extraction Example: Experimental groups, control group(s) and number of animals per group. ">Data to be extracted: study design Example: Species, sex, weight, age, co‐morbidity, anaesthetic agent used, method of induction of cardiac ischemia, duration of ischemia and duration

2019 PROSPERO

52. Therapeutic hypothermia after paediatric cardiac arrest: Pooled randomized controlled trials

Therapeutic hypothermia after paediatric cardiac arrest: Pooled randomized controlled trials Separate trials to evaluate therapeutic hypothermia after paediatric cardiac arrest for out-of-hospital and in-hospital settings reported no statistically significant differences in survival with favourable neurobehavioral outcome or safety compared to therapeutic normothermia. However, larger sample sizes might detect smaller clinical effects. Our aim was to pool data from identically conducted trials (...) of blood-product use, infection, and serious cardiac arrhythmia adverse events, and 28-day mortality, did not differ between groups.Analysis of combined data from two paediatric cardiac arrest targeted temperature management trials including both in-hospital and out-of-hospital cases revealed that hypothermia, as compared with normothermia, did not confer a significant benefit in survival with favourable functional outcome at one year.Copyright © 2018 Elsevier B.V. All rights reserved.

2018 EvidenceUpdates

53. Incidence, outcomes and guideline compliance of out-of-hospital maternal cardiac arrest resuscitations: A population-based cohort study

Incidence, outcomes and guideline compliance of out-of-hospital maternal cardiac arrest resuscitations: A population-based cohort study Incidence and survival rates after cardiac arrest among pregnant women are reported for in-hospital cardiac arrests; the incidence and outcomes of maternal out-of-hospital cardiac arrest (OHCA) are unknown. Current cardiopulmonary resuscitation guidelines contain recommendations specific to this population; compliance with these has not been investigated.To

2018 EvidenceUpdates

54. Which Compression-to-Ventilation Ratio Yields Better Cardiac Arrest Outcomes? (SRS therapy)

Which Compression-to-Ventilation Ratio Yields Better Cardiac Arrest Outcomes? (SRS therapy) TAKE-HOME MESSAGE Continuous compressions with asynchronous ventilations and a compression-to- ventilation ratio of 30:2 resulted in improved outcomes in adults in cardiopulmonary arrest, whereas either 30:2 or 15:2 improved outcomes in children. Which Compression-to-Ventilation Ratio Yields Better Cardiac Arrest Outcomes? EBEM Commentators Dhimitri A. Nikolla, DO Jestin N. Carlson, MD, MS Department (...) evidence has suggested harm from long pauses in chest compressions, 1,2 greater emphasis has been placed on bystander compression-only CPR and continuous-compression CPR by out-of-hospital providers. 3 In addition, hyperventilation may negatively affect outcomes. 4,5 As such, there is equipoise in regard to the ideal compression-to- ventilation ratio in cardiac arrest, and limited high-quality data exist. The study by Nichol et al 6 comparing continuous- compression CPR to 30:2 CPR represents

2018 Annals of Emergency Medicine Systematic Review Snapshots

55. Does Spontaneous Cardiac Motion, Identified With Point-of-Care Echocardiography During Cardiac Arrest, Predict Survival? (SRS prognosis)

Does Spontaneous Cardiac Motion, Identified With Point-of-Care Echocardiography During Cardiac Arrest, Predict Survival? (SRS prognosis) TAKE-HOME MESSAGE Point-of-care echocardiography demonstrating no spontaneous cardiac motion is associated with lower likelihood of return of spontaneous circulation and survival to hospital admission. This may be used to assist with decisionmaking about resuscitation termination. Does Spontaneous Cardiac Motion, Identi?ed With Point-of-Care Echocardiography (...) During Cardiac Arrest, Predict Survival? EBEM Commentators Michael D. April, MD, DPhil Brit Long, MD Department of Emergency Medicine SAUSHEC Fort Sam Houston, TX Results Summary of meta-analysis outcomes for 1,695 patients and 15 studies. Outcome No. Studies No. Patients* Sensitivity (95% CI) Speci?city (95% CI) LRD (95% CI) LR– (95% CI) AUROC (95% CI) I 2 (95% CI) ROSC 8 543 95 (72–99) 80 (63–91) 4.8 (2.5–9.4) 0.06 (0.01–0.39) 0.93 (0.91–0.95) 98 (97–99) Survival to hospital admission 10 1,018 90

2018 Annals of Emergency Medicine Systematic Review Snapshots

56. Effectiveness of antiarrhythmic drugs for shockable cardiac arrest: A systematic review

Effectiveness of antiarrhythmic drugs for shockable cardiac arrest: A systematic review The purpose of this systematic review is to provide up-to-date evidence on effectiveness of antiarrhythmic drugs for shockable cardiac arrest to help inform the 2018 International Liaison Committee on Resuscitation Consensus on Science with Treatment Recommendations.A search was conducted in electronic databases Medline, Embase, and Cochrane Library from inception to August 15, 2017.Of the 9371 citations (...) , the results showed a significant increase for lidocaine compared with placebo (RR = 1.16; 95% CI, 1.03-1.29, p = 0.01).The high level evidence supporting the use of antiarrhythmic drugs during CPR for shockable cardiac arrest is limited and showed no benefit for critical outcomes of survival at hospital discharge, survival with favorable neurological function and long-term survival. Future high quality research is needed to confirm these findings and also to evaluate the role of administering

2018 EvidenceUpdates

57. The CPR Coach – A Paradigm Shift in Resuscitation Teams for Cardiac Arrest Management

The CPR Coach – A Paradigm Shift in Resuscitation Teams for Cardiac Arrest Management The CPR Coach – A Paradigm Shift in Resuscitation Teams for Cardiac Arrest Management - CanadiEM The CPR Coach – A Paradigm Shift in Resuscitation Teams for Cardiac Arrest Management In , by Adam Cheng September 10, 2018 Survival outcomes from cardiac arrest remain poor despite recent advancements in resuscitation science and education. The delivery of high quality cardiopulmonary resuscitation (CPR) during (...) cardiac arrest is a key component of clinical care. The delivery of high quality CPR is associated with improved survival outcomes. Unfortunately, many studies have demonstrated that providers consistent struggle to provide guideline compliant CPR during cardiac arrest care 1 , 2 . The formula for survival in cardiac arrest outlines three key components that contribute to survival outcomes: medical science, educational efficiency, and local implementation 3 . Various research groups have explored

2018 CandiEM

58. Efficacy and Safety of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation After In-Hospital Cardiac Arrest

Efficacy and Safety of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation After In-Hospital Cardiac Arrest PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2018 PedsCCM Evidence-Based Journal Club

59. Survival and Long-Term Functional Outcomes for Children With Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation

Survival and Long-Term Functional Outcomes for Children With Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2018 PedsCCM Evidence-Based Journal Club

60. Efficacy and safety of mechanical versus manual compression in cardiac arrest - A Bayesian network meta-analysis

Efficacy and safety of mechanical versus manual compression in cardiac arrest - A Bayesian network meta-analysis To compare relative efficacy and safety of mechanical compression devices (AutoPulse and LUCAS) with manual compression in patients with cardiac arrest undergoing cardiopulmonary resuscitation (CPR).For this Bayesian network meta-analysis, seven randomized controlled trials (RCTs) were selected using PubMed/Medline, EMBASE, and CENTRAL (Inception- 31 October 2017). For all (...) the outcomes, median estimate of odds ratio (OR) from the posterior distribution with corresponding 95% credible interval (Cr I) was calculated. Markov chain Monte Carlo (MCMC) modeling was used to estimate the relative ranking probability of each intervention based on surface under the cumulative ranking curve (SUCRA).In analysis of 12, 908 patients with cardiac arrest [AutoPulse (2, 608 patients); LUCAS (3, 308 patients) and manual compression (6, 992 patients)], manual compression improved survival

2018 EvidenceUpdates