Latest & greatest articles for caries

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on caries or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on caries and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for caries

101. Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries

Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together (...) Topics Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries Svetlana Tikhonova, DMD, MSc, PhD . Overview Systematic Review Conclusion Sealants to prevent occlusal caries in permanent molars are recommended, but the benefits in different caries risk populations and types of sealants have yet to be established. Critical Summary Assessment Resin-based sealants in permanent molars reduces risk of experiencing caries up to 48 months compared

2015 ADA Center for Evidence-Based Dentistry

102. Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries

Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together (...) Topics Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries Svetlana Tikhonova, DMD, MSc, PhD . Overview Systematic Review Conclusion Sealants to prevent occlusal caries in permanent molars are recommended, but the benefits in different caries risk populations and types of sealants have yet to be established. Critical Summary Assessment Resin-based sealants in permanent molars reduces risk of experiencing caries up to 48 months compared

2015 ADA Center for Evidence-Based Dentistry

103. Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries

Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together (...) Topics Sealing pits and fissures of permanent molars in children and adolescents is effective in controlling dental caries Svetlana Tikhonova, DMD, MSc, PhD . Overview Systematic Review Conclusion Sealants to prevent occlusal caries in permanent molars are recommended, but the benefits in different caries risk populations and types of sealants have yet to be established. Critical Summary Assessment Resin-based sealants in permanent molars reduces risk of experiencing caries up to 48 months compared

2015 ADA Center for Evidence-Based Dentistry

104. Chlorhexidine treatment for the prevention of dental caries in children and adolescents. (PubMed)

Chlorhexidine treatment for the prevention of dental caries in children and adolescents. Dental caries (tooth decay) is a common disease that is preventable by reducing the dietary intake of free sugars and using topical sodium fluoride products. An antibacterial agent known as chlorhexidine may also help prevent caries. A number of over-the-counter and professionally administered chlorhexidine-based preparations are available in a variety of formulations and in a range of strengths. Although (...) previous reviews have concluded that some formulations of chlorhexidine may be effective in inhibiting the progression of established caries in children, there is currently a lack of evidence to either claim or refute a benefit for its use in preventing dental caries.To assess the effects of chlorhexidine-containing oral products (toothpastes, mouthrinses, varnishes, gels, gums and sprays) on the prevention of dental caries in children and adolescents.We searched the Cochrane Oral Health Group Trials

Full Text available with Trip Pro

2015 Cochrane

105. [Incomplete dental caries restoration: a systematic review and meta-analysis].

[Incomplete dental caries restoration: a systematic review and meta-analysis]. 25839368 2016 01 20 2018 12 02 2212-0289 109 1 2015 Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen Z Evid Fortbild Qual Gesundhwes [Incomplete dental caries restoration: a systematic review and meta-analysis]. 56-8 10.1016/j.zefq.2015.01.009 S1865-9217(15)00011-2 Schwendicke Falk F Abteilung für Zahnerhaltung und Präventivzahnmedizin, Centrum für Zahn-, Mund- und Kieferheilkunde, Charité (...) - Universitätsmedizin Berlin, Berlin, Deutschland. Electronic address: falk.schwendicke@charite.de. ger Journal Article Meta-Analysis Review Systematic Review Unvollständige Kariesentfernung: Eine systematische Übersicht und Meta-Analyse. 2015 02 28 Netherlands Z Evid Fortbild Qual Gesundhwes 101477604 1865-9217 IM Z Evid Fortbild Qual Gesundhwes. 2015;109(1):58 25839369 Dental Care methods Dental Caries complications therapy Dental Restoration, Permanent methods Evidence-Based Dentistry Humans Recurrence Risk

2015 Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen

106. [Comment on the practical relevance of the David Sackett Award 2014 excellent work "Incomplete removal of caries: A systematic review and meta-analysis" by Falk Schwendicke].

[Comment on the practical relevance of the David Sackett Award 2014 excellent work "Incomplete removal of caries: A systematic review and meta-analysis" by Falk Schwendicke]. 25839369 2016 01 20 2018 12 02 2212-0289 109 1 2015 Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen Z Evid Fortbild Qual Gesundhwes [Comment on the practical relevance of the David Sackett Award 2014 excellent work "Incomplete removal of caries: A systematic review and meta-analysis" by Falk (...) Gesundhwes 101477604 1865-9217 IM Z Evid Fortbild Qual Gesundhwes. 2015;109(1):56-8 25839368 Dental Care methods Dental Caries complications therapy Dental Restoration, Permanent methods Evidence-Based Dentistry Humans 2015 4 4 6 0 2015 4 4 6 0 2016 1 21 6 0 ppublish 25839369 S1865-9217(15)00012-4 10.1016/j.zefq.2015.01.010

2015 Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen

107. Lactobacillus Salivarius Containing Probiotics May Have Benefits Similar to Xylitol in Decreasing Caries Risk

Lactobacillus Salivarius Containing Probiotics May Have Benefits Similar to Xylitol in Decreasing Caries Risk UTCAT2840, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Lactobacillus Salivarius Containing Probiotics May Have Benefits Similar to Xylitol in Decreasing Caries Risk Clinical Question How effective are Lactobacillus salivarius containing probiotic tablets as compared to xylitol in decreasing caries risk (...) ? Clinical Bottom Line Lactobacillus salivarius containing probiotic may have the added benefit of salivary buffering capacity over xylitol alone, based on one study of 64 individuals. Double blind randomized control trials should be performed before clinical recommendation of Lactobacillus salivarius to decrease caries risk. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Nishihara/2014 1 study/64

2015 UTHSCSA Dental School CAT Library

108. Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered

Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered UTCAT2881, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered Clinical Question Are lasers less likely than rotary burs to cause a patient (...) pain during caries excavation when the patient has not received anesthesia? Clinical Bottom Line For patients in need of caries excavation who will not allow or have contraindications to the use of local anesthetic, Er:YAG lasers are less likely than rotary burs to cause a patient discomfort. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Dommisch/2008 26 adults with 102 carious lesions Randomized

2015 UTHSCSA Dental School CAT Library

109. Chlorhexidine-Thymol Varnish May Provide a Benefit in the Prevention of Root Caries in High Caries Risk Individuals with Poor Oral Hygiene

Chlorhexidine-Thymol Varnish May Provide a Benefit in the Prevention of Root Caries in High Caries Risk Individuals with Poor Oral Hygiene UTCAT2890, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Chlorhexidine-Thymol Varnish May Provide a Benefit in the Prevention of Root Caries in High Caries Risk Individuals with Poor Oral Hygiene Clinical Question In adults at high caries risk, is application of Chlorhexidine (...) varnish better than Fluoride varnish in reducing root caries incidence? Clinical Bottom Line Chlorhexidine-Thymol Varnish (CHX-V), when applied to high risk patients with poor oral hygiene, limits the incidence of root carries as well as reduces the rate of growth of existing lesions. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Slot/2011 574 adult patients in 6 included studies Meta-Analysis Key

2015 UTHSCSA Dental School CAT Library

110. No Strong Evidence in Support of Either Chlorhexidine Mouthwash or Varnish in Preventing Dental Caries

No Strong Evidence in Support of Either Chlorhexidine Mouthwash or Varnish in Preventing Dental Caries UTCAT2885, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title No Strong Evidence in Support of Either Chlorhexidine Mouthwash or Varnish in Preventing Dental Caries Clinical Question Is chlorhexidine mouthwash more effective in preventing caries development than chlorhexidine varnish? Clinical Bottom Line The available (...) clinical evidence supporting the efficacy of chlorhexidine varnish on preventing dental caries is weak. There is also no evidence to support the efficacy of chlorhexidine mouthwash in preventing dental caries. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Autio-Gold/2008 All age groups Literature review Key results A review of the current literature on chlorhexidine mouthwashes did not reveal

2015 UTHSCSA Dental School CAT Library

111. Cavitation of Proximal Caries Lesions Can Be Determined More Accurately on Bitewing Radiographs When the Radiolucent Depth Is > 0.5 mm From the DEJ

Cavitation of Proximal Caries Lesions Can Be Determined More Accurately on Bitewing Radiographs When the Radiolucent Depth Is > 0.5 mm From the DEJ UTCAT2882, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Cavitation of Proximal Caries Lesions Can Be Determined More Accurately on Bitewing Radiographs When the Radiolucent Depth Is > 0.5 mm From the DEJ Clinical Question How accurately can proximal caries lesion (...) cavitation be predicted from the depth of the radiolucency in bitewing radiograph? Clinical Bottom Line Cavitation of proximal caries lesions can be determined accurately on bitewing radiographs; the probability of cavitation increases when lesions are 0.5 mm or deeper from the DEJ on the radiograph. However, CBCT has been shown to be more sensitive in detecting proximal cavitation than bitewing radiographs. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year

2015 UTHSCSA Dental School CAT Library

112. Glass Ionomer Restorations May Be More Effective Than Resin Composites at Preventing Recurrent Caries in Class V Lesions Over a 5-Year Period

Glass Ionomer Restorations May Be More Effective Than Resin Composites at Preventing Recurrent Caries in Class V Lesions Over a 5-Year Period UTCAT2889, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Glass Ionomer Restorations May Be More Effective Than Resin Composites at Preventing Recurrent Caries in Class V Lesions Over a 5-Year Period Clinical Question In adults with carious Class 5 lesions, are glass ionomers (...) more effective than traditional resin composites at preventing recurrent caries over a 5-year period? Clinical Bottom Line Although there is no statistical difference between glass ionomer and resin composite in preventing recurrent caries in most patients, there may be some added benefit with the fluoride-releasing effect of glass ionomer in more compromised patients, such as the xerostomatic patient with poor oral hygiene. Best Evidence (you may view more info by clicking on the PubMed ID link

2015 UTHSCSA Dental School CAT Library

113. Silver Nanoparticle (AgNP)-Containing Resin Bonding Systems Significantly Reduced the Viability of Caries-Related Bacteria and Plaque Biofilms

Silver Nanoparticle (AgNP)-Containing Resin Bonding Systems Significantly Reduced the Viability of Caries-Related Bacteria and Plaque Biofilms UTCAT2841, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Silver Nanoparticle (AgNP)-Containing Resin Bonding Systems Significantly Reduced the Viability of Caries-Related Bacteria and Plaque Biofilms Clinical Question In patients with class 1, class 2, or class 5 composite (...) restorations, is the incidence of secondary caries lower when using silver nanoparticle-incorporated resin bonding systems compared to conventional resin bonding systems? Clinical Bottom Line Studies performed in vitro demonstrated the inhibition of caries-related Streptococcus mutans and plaque-forming oral bacteria when AgNPs were incorporated into resin bonding systems. This is based on studies showing a reduction in metabolic activity, number of colony forming units (CFUs), and lactic acid production

2015 UTHSCSA Dental School CAT Library

114. In Pediatric Patients, Use of Removable Orthodontic Appliances May Lead to an Increased Risk of Dental Caries

In Pediatric Patients, Use of Removable Orthodontic Appliances May Lead to an Increased Risk of Dental Caries UTCAT2816, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title In Pediatric Patients, Use of Removable Orthodontic Appliances May Lead to an Increased Risk of Dental Caries Clinical Question In pediatric patients, does use of a removable orthodontic appliance increase the risk of dental caries? Clinical Bottom Line (...) The use of removable appliances is another variable to consider when determining the caries risk status of patients, as these patients have been found to harbor a higher frequency of the caries-promoting bacteria Streptococcus mutans. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Batoni/2001 147 patients aged 8-10 years Cross Sectional Study Key results S. mutans, which is associated with the onset

2015 UTHSCSA Dental School CAT Library

115. Xylitol-containing products for preventing dental caries in children and adults. (PubMed)

Xylitol-containing products for preventing dental caries in children and adults. Dental caries is a highly prevalent chronic disease which affects the majority of people. It has been postulated that the consumption of xylitol could help to prevent caries. The evidence on the effects of xylitol products is not clear and therefore it is important to summarise the available evidence to determine its effectiveness and safety.To assess the effects of different xylitol-containing products (...) for the prevention of dental caries in children and adults.We searched the following electronic databases: the Cochrane Oral Health Group Trials Register (to 14 August 2014), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2014, Issue 7), MEDLINE via OVID (1946 to 14 August 2014), EMBASE via OVID (1980 to 14 August 2014), CINAHL via EBSCO (1980 to 14 August 2014), Web of Science Conference Proceedings (1990 to 14 August 2014), Proquest Dissertations and Theses (1861 to 14

Full Text available with Trip Pro

2015 Cochrane

116. Sugar Substitutes May Reduce Tooth Demineralization in High Caries Patients 03/17/2015 Huy Le

Sugar Substitutes May Reduce Tooth Demineralization in High Caries Patients 03/17/2015 Huy Le UTCAT2817, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Sugar Substitutes May Reduce Tooth Demineralization in High Caries Patients Clinical Question In a patient with high risk caries how do dietary sugar substitutes compared to sucrose affect demineralization on teeth surfaces? Clinical Bottom Line Sugar substitutes have (...) shown to decrease the chances of tooth demineralization when assessing for enamel pH, caries incidence and tooth surface hardness compared to conventional sucrose diets. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Giacaman/2013 Patient Group bovine enamel slabs Laboratory study Key results Giacaman showed that there was a noticeable difference between artificial aspartame substitute diet and sucrose

2015 UTHSCSA Dental School CAT Library

117. Dental caries: can be drug related

Dental caries: can be drug related Prescrire IN ENGLISH - Spotlight ''Dental caries: can be drug related'', 1 February 2015 {1} {1} {1} | | > > > Dental caries: can be drug related Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Dental caries: can be drug related Some drugs expose patients to dental caries due to their composition or their action (...) . The quasi constant presence of sugars or food in the mouth, insufficient brushing and a decrease in the quantity or the quality of saliva are all factors that contribute to the development of dental caries. Sometimes, drugs expose patients to the risk of dental caries, through various mechanisms: via a high sugar content, by causing dry mouth, by increasing acids in the mouth, or by damaging the tooth enamel. Medicinal products high in sugar include syrups, pastilles, tablets to be sucked and homeopathy

2015 Prescrire

118. Micro-Computed Tomography is As Good As Histologic Sectioning as a Gold Standard for in vitro Determination of Proximal Caries Depth

Micro-Computed Tomography is As Good As Histologic Sectioning as a Gold Standard for in vitro Determination of Proximal Caries Depth UTCAT2796, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Micro-Computed Tomography is As Good As Histologic Sectioning as a Gold Standard for in vitro Determination of Proximal Caries Depth Clinical Question For the in vitro determination of proximal caries depth, is micro-computed (...) a sensitivity of 1 (0.79-1), specificity of 0.97 (0.84-0.99), PPV of 0.94 (0.0.71-0.99), NPV of 1 (0.89-1) and accuracy of 0.98. Forty-eight primary molar proximal surfaces were evaluated; 9 sound, 9 caries in outer enamel, 14 caries in inner enamel, 4 caries beyond CEJ but not spread in dentin, 4 caries that spread in the outer dentin and 8 caries in the inner dentin. Histology samples were 300 µm thick. #2) Mitropoulos/2010 Laboratory study Key results Kappa statistic agreement for micro-CT and histology

2014 UTHSCSA Dental School CAT Library

119. Global Research Trends on Early-Life Feeding Practices and Early Childhood Caries: a Systematic Review. (PubMed)

Global Research Trends on Early-Life Feeding Practices and Early Childhood Caries: a Systematic Review. Describe the epidemiologic literature related to early-life feeding practices and early childhood caries (ECC) with regard to publication attributes and trends in these attributes over time.Systematic literature review including electronic and manual searches (in BIOSIS, CINAHL, Cochrane Library, LILACS, MEDLINE, Web of Science, and WHOLIS), covering the years 1990-2013. Attributes (...) of publications meeting a priori inclusion criteria were abstracted and organized by global region and trends over time. Attributes included country of origin and study design of included publications and age and caries prevalence of the populations studied.244 publications drawn from 196 independent study populations were included. The number of publications and the countries represented increased over time, although some world regions remained underrepresented. Most publications were cross sectional (75

Full Text available with Trip Pro

2014 Journal of oral diseases

120. Inconclusive caries-preventive results with chlorhexidine varnish in children and adolescents

Inconclusive caries-preventive results with chlorhexidine varnish in children and adolescents Inconclusive caries-preventive results with chlorhexidine varnish in children and adolescents ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all. Together. Take advantage of endorsed, discounted (...) business products Purchase ADA products Access oral-health information for the public and ADA Find-A-Dentist Partnerships and Commissions Learn about ADA CERP recognition, look up CERP recognized CE providers and find CE courses. Explore CODA's role and find accredited schools and programs Learn about the examinations used in licensing dentists and dental hygienists Learn about recognized dental specialties and certifying boards Evidence Education * Associated Topics Inconclusive caries-preventive

2014 ADA Center for Evidence-Based Dentistry