Latest & greatest articles for children

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Top results for children

41. Families and Schools Together (FAST) for improving outcomes for children and their families. (PubMed)

Families and Schools Together (FAST) for improving outcomes for children and their families. Parents and carers have a major influence on children's learning and development from birth, through the school years, and into adulthood. Parental contributions to education include providing a secure environment in which to learn, providing intellectual stimulation, transmitting social norms and values, shaping the child's resilience through fostering literacy and problem-solving, and encouraging (...) personal and social aspiration. Increasingly, providers of formalised education are recognising the primary role of parents, carers, and the wider family, as well as peers and the environment, in shaping children's education, health, and life experiences.To assess the effectiveness of the Families and Schools Together (FAST) programme in improving outcomes among children and their families.Between October 2018 and December 2018, we searched CENTRAL, MEDLINE, Embase, PsycINFO, 11 additional databases

2019 Cochrane

42. WITHDRAWN: Operative caries management in adults and children. (PubMed)

WITHDRAWN: Operative caries management in adults and children. The management of dental caries has traditionally involved removal of all soft demineralised dentine before a filling is placed. However, the benefits of complete caries removal have been questioned because of concerns about the possible adverse effects of removing all soft dentine from the tooth. Three groups of studies have also challenged the doctrine of complete caries removal by sealing caries into teeth using three different

2019 Cochrane

43. Development and validation of a prediction model for fat mass in children and adolescents: meta-analysis using individual participant data. (PubMed)

Development and validation of a prediction model for fat mass in children and adolescents: meta-analysis using individual participant data. To develop and validate a prediction model for fat mass in children aged 4-15 years using routinely available risk factors of height, weight, and demographic information without the need for more complex forms of assessment.Individual participant data meta-analysis.Four population based cross sectional studies and a fifth study for external validation (...) , United Kingdom.A pooled derivation dataset (four studies) of 2375 children and an external validation dataset of 176 children with complete data on anthropometric measurements and deuterium dilution assessments of fat mass.Multivariable linear regression analysis, using backwards selection for inclusion of predictor variables and allowing non-linear relations, was used to develop a prediction model for fat-free mass (and subsequently fat mass by subtracting resulting estimates from weight) based

2019 BMJ

44. Interventions for preventing obesity in children. (PubMed)

Interventions for preventing obesity in children. Prevention of childhood obesity is an international public health priority given the significant impact of obesity on acute and chronic diseases, general health, development and well-being. The international evidence base for strategies to prevent obesity is very large and is accumulating rapidly. This is an update of a previous review.To determine the effectiveness of a range of interventions that include diet or physical activity components (...) , or both, designed to prevent obesity in children.We searched CENTRAL, MEDLINE, Embase, PsychINFO and CINAHL in June 2015. We re-ran the search from June 2015 to January 2018 and included a search of trial registers.Randomised controlled trials (RCTs) of diet or physical activity interventions, or combined diet and physical activity interventions, for preventing overweight or obesity in children (0-17 years) that reported outcomes at a minimum of 12 weeks from baseline.Two authors independently

2019 Cochrane

45. Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children. (PubMed)

Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children. Fluid therapy is one of the main interventions provided for critically ill patients, although there is no general consensus regarding the type of solution. Among crystalloid solutions, 0.9% saline is the most commonly administered. Buffered solutions may offer some theoretical advantages (less metabolic acidosis, less electrolyte disturbance), but the clinical relevance of these remains unknown.To (...) examining buffered solutions versus intravenous 0.9% saline in a critical care setting (resuscitation or maintenance). We included studies on participants with critical illness (including trauma and burns) or undergoing emergency surgery during critical illness who required intravenous fluid therapy. We included studies of adults and children. We included studies with more than two arms if they fulfilled all of our inclusion criteria. We excluded studies performed in persons undergoing elective surgery

2019 Cochrane

46. Community first responders for out-of-hospital cardiac arrest in adults and children. (PubMed)

Community first responders for out-of-hospital cardiac arrest in adults and children. Mobilization of community first responders (CFRs) to the scene of an out-of-hospital cardiac arrest (OHCA) event has been proposed as a means of shortening the interval from occurrence of cardiac arrest to performance of cardiopulmonary resuscitation (CPR) and defibrillation, thereby increasing patient survival.To assess the effect of mobilizing community first responders (CFRs) to out-of-hospital cardiac (...) arrest events in adults and children older than four weeks of age, in terms of survival and neurological function.We searched the following databases for relevant trials in January 2019: CENTRAL, MEDLINE (Ovid SP), Embase (Ovid SP), and Web of Science. We also searched the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) and ClinicalTrials.gov, and we scanned the abstracts of conference proceedings of the American Heart Association and the European Resuscitation

2019 Cochrane

47. Singing as an adjunct therapy for children and adults with cystic fibrosis. (PubMed)

Singing as an adjunct therapy for children and adults with cystic fibrosis. Cystic fibrosis is a genetically inherited, life-threatening condition that affects major organs. The management of cystic fibrosis involves a multi-faceted daily treatment regimen that includes airway clearance techniques, pancreatic enzymes and other medications. Previous studies have found that compliance with this intensive treatment is poor, especially among adolescents. Because of both the nature and consequences (...) and pulmonary function of children and adults with cystic fibrosis.We searched the Group's Cystic Fibrosis Trials Register and the Cochrane Central Register of Controlled Trials. Date of latest search: 07 January 2019.We also searched major allied complementary data bases, and clinical trial registers. Additionally, we handsearched relevant conference proceedings and journals. Date of latest search: 28 March 2019.Randomised controlled trials in which singing (as an adjunct intervention) is compared

2019 Cochrane

48. Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study. (PubMed)

Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study. To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood.Retrospective cohort study.Population based birth registry linked with health administrative databases in the province of Ontario, Canada.All live births from November (...) 2009 through October 2010 (n=104 249) were included, and children were followed until 5 years of age to ascertain study outcomes.Rates of immune related (infectious diseases, asthma), non-immune related (neoplasms, sensory disorders), and non-specific morbidity outcomes (urgent or inpatient health services use, pediatric complex chronic conditions) were evaluated from birth to 5 years of age; under-5 childhood mortality was also assessed. Propensity score weighting was used to adjust hazard ratios

2019 BMJ

49. C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia. (PubMed)

C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia. Achondroplasia is a genetic disorder that inhibits endochondral ossification, resulting in disproportionate short stature and clinically significant medical complications. Vosoritide is a biologic analogue of C-type natriuretic peptide, a potent stimulator of endochondral ossification.In a multinational, phase 2, dose-finding study and extension study, we evaluated the safety and side-effect profile of vosoritide (...) in children (5 to 14 years of age) with achondroplasia. A total of 35 children were enrolled in four sequential cohorts to receive vosoritide at a once-daily subcutaneous dose of 2.5 μg per kilogram of body weight (8 patients in cohort 1), 7.5 μg per kilogram (8 patients in cohort 2), 15.0 μg per kilogram (10 patients in cohort 3), or 30.0 μg per kilogram (9 patients in cohort 4). After 6 months, the dose in cohort 1 was increased to 7.5 μg per kilogram and then to 15.0 μg per kilogram, and in cohort 2

2019 NEJM

50. Depression in children and young people: identification and management

Depression in children and young people: identification and management Depression in children and y Depression in children and young people: oung people: identification and management identification and management NICE guideline Published: 25 June 2019 www.nice.org.uk/guidance/ng134 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline (...) inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Depression in children and young people: identification and management (NG134) © NICE 2019. All rights reserved. Subject to Notice of rights (https

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

51. Physical activity helps children to deal with life’s challenges

Physical activity helps children to deal with life’s challenges Physical activity helps children to deal with life’s challenges - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Press release Physical activity helps children to deal with life’s challenges Public Health England, Disney UK and Sport England launch new Change4Life campaign to inspire children to get more active. Published 4 July 2019 From: A new (...) survey from Change4Life and Disney UK has found that less than half of parents are aware that physical activity can build children’s self-confidence (49%), reduce anxiety (47%) and improve their self-esteem (46%). Just 16% (1 in 6) think that physical activity can help children develop attributes which make it easier to cope with life’s little set-backs. Evidence shows that children and young people who are more active have more confidence, higher self-esteem, less anxiety and stress and better

2019 Public Health England

52. Lead toxicity with a new focus: Addressing low-level lead exposure in Canadian children

Lead toxicity with a new focus: Addressing low-level lead exposure in Canadian children Although acute and subacute lead toxicity requiring active treatment is rare in Canada, paediatricians need to be aware of new evidence linking lower lead levels to neurodevelopmental deficits. Health Canada has identified potential exposures occurring prenatally, in infancy and during early childhood from food and water, household dust, soil and mouthing products that contain lead. Children

2019 Canadian Paediatric Society

53. Transversus Abdominal Plane Block in Children: Efficacy and Safety: A Randomized Clinical Study and Pharmacokinetic Profile

Transversus Abdominal Plane Block in Children: Efficacy and Safety: A Randomized Clinical Study and Pharmacokinetic Profile The transversus abdominis plane (TAP) block has become a common regional anesthesia technique for pain management in a wide variety of abdominal procedures. Evidence to support any particular local anesthetic regimen as well as pharmacokinetic and systemic toxicity risks of TAP block remain insufficiently studied in children. The aim of this study was to compare (...) the analgesic effects and investigate pharmacokinetic profile of levobupivacaine after ultrasound-guided TAP block using a low volume/high concentration (LVHC) or a high volume/low concentration (HVLC) solution in children.This prospective randomized study included children scheduled for day-case inguinal surgery. Children were randomized to receive TAP block using 0.4 mg·kg levobupivacaine as either HVLC (0.2 mL·kg of 0.2% levobupivacaine) or LVHC (0.1 mL·kg of 0.4% levobupivacaine). The primary outcome

2019 EvidenceUpdates

54. No Effect of Glucomannan on Body Weight Reduction in Children and Adolescents with Overweight and Obesity: A Randomized Controlled Trial

No Effect of Glucomannan on Body Weight Reduction in Children and Adolescents with Overweight and Obesity: A Randomized Controlled Trial To assess the efficacy of water-soluble dietary fiber, glucomannan supplementation, on the body mass index (BMI) in children with overweight or obesity.In this randomized, double-blind, placebo-controlled trial, we enrolled 96 children aged 6-17 years with overweight or obesity based on the World Health Organization growth criteria (>+1 SD or >+2 SD (...) group had lower total and low-density lipoprotein cholesterol concentrations at 12 weeks. In addition, the blood pressure was greater at 12 weeks (systolic) and at 24 weeks (diastolic) in the glucomannan group. No differences between the groups in adverse events and other secondary outcomes were observed.Glucomannan supplementation compared with placebo had no effect on weight reduction in children with overweight and obesity.ClinicalTrials.govNCT02280772.Copyright © 2019 Elsevier Inc. All rights

2019 EvidenceUpdates

55. Ultrasonographic Guidance to Improve First-Attempt Success in Children With Predicted Difficult Intravenous Access in the Emergency Department: A Randomized Controlled Trial

Ultrasonographic Guidance to Improve First-Attempt Success in Children With Predicted Difficult Intravenous Access in the Emergency Department: A Randomized Controlled Trial We determine whether ultrasonographically guided intravenous line placement improves the rate of first-attempt success by 20% for children with predicted difficult intravenous access. Secondary objectives included determining whether ultrasonographically guided intravenous line placement reduces the attempt number, improves (...) time to access or parental satisfaction, or affects intravenous line survival and complications.This was a prospective, randomized controlled trial conducted in an urban tertiary care pediatric emergency department that enrolled a convenience sample of children requiring an intravenous line and who were predicted to have difficult intravenous access according to a previously validated score. Participants were randomized to traditional or ultrasonographically guided intravenous line placement

2019 EvidenceUpdates

56. British Association of Dermatologists guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in children and young people

British Association of Dermatologists guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in children and young people British Association of Dermatologists' guidelines for the management of Stevens–Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018 - McPherson - 2019 - British Journal of Dermatology - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search (...) term Search term The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Navigation Bar Menu Guidelines Free Access British Association of Dermatologists' guidelines for the management of Stevens–Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018 Corresponding Author E-mail address: E-mail address: Oxford University Hospitals NHS Foundation Trust, Old Road, Headington, Oxford, OX3 7LE U.K Correspondence Tess McPherson. E‐mails

2019 British Association of Dermatologists

57. Cultural adaptation of an existing children's weight management programme: the CHANGE intervention and feasibility RCT

Cultural adaptation of an existing children's weight management programme: the CHANGE intervention and feasibility RCT Cultural adaptation of an existing children's weight management programme: the CHANGE intervention and feasibility RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find (...) the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} The culturally adapted children's weight management programme was highly acceptable to children and families of all ethnicities and, although logistical problems were identified, a future trial is feasible. {{author}} {{($index , , , , , , , , , , , , , & . Miranda Pallan 1, * , Tania Griffin 1 , Kiya L Hurley 1 , Emma Lancashire 1 , Jacqueline Blissett 2, 3 , Emma Frew 1 , Laura

2019 NIHR HTA programme

58. Do Exercise Interventions Improve Balance for Children and Adolescents With Down Syndrome? A Systematic Review

Do Exercise Interventions Improve Balance for Children and Adolescents With Down Syndrome? A Systematic Review Youths with Down syndrome are characterized by deficits in balance/postural stability. One way to palliate balance deficits among this population is through exercise interventions. However, to the authors' knowledge, the effects of exercise interventions designed to improve the balance of youths with Down syndrome have never been systematically reviewed.The purpose of this review (...) of exercise interventions designed to improve balance in youths with Down syndrome were included.Two authors selected the studies and extracted their characteristics and results. Three authors assessed the risk of bias in the studies using the Cochrane Collaboration tool.Eleven studies, published between 2010 and 2017, met the inclusion criteria. The findings showed that exercise interventions were more effective than control conditions for improving the static balance of children with Down syndrome

2019 EvidenceUpdates

59. Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study. (PubMed)

Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study. Pneumonia is the leading cause of death among children younger than 5 years. In this study, we estimated causes of pneumonia in young African and Asian children, using novel analytical methods applied to clinical and microbiological findings.We did a multi-site, international case-control study in nine study sites in seven countries (...) : Bangladesh, The Gambia, Kenya, Mali, South Africa, Thailand, and Zambia. All sites enrolled in the study for 24 months. Cases were children aged 1-59 months admitted to hospital with severe pneumonia. Controls were age-group-matched children randomly selected from communities surrounding study sites. Nasopharyngeal and oropharyngeal (NP-OP), urine, blood, induced sputum, lung aspirate, pleural fluid, and gastric aspirates were tested with cultures, multiplex PCR, or both. Primary analyses were restricted

2019 Lancet

60. Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years. (PubMed)

Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years. Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills. We (...) examined the benefits and harms of social skills training on social skills, emotional competencies, general behaviour, ADHD symptoms, performance in school of children with ADHD, and adverse events.To assess the beneficial and harmful effects of social skills training in children and adolescents with ADHD.In July 2018, we searched CENTRAL, MEDLINE, Embase, PsycINFO, 4 other databases and two trials registers.We also searched online conference abstracts, and contacted experts in the field

2019 Cochrane