Latest & greatest articles for chlorhexidine

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Top results for chlorhexidine

121. Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery (PubMed)

Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery Surgical-site infection increases morbidity, mortality and financial burden. The preferred topical antiseptic agent (chlorhexidine or povidone-iodine) for preoperative skin cleansing is unclear.A meta-analysis of clinical trials was conducted to determine whether preoperative antisepsis with chlorhexidine or povidone-iodine reduced surgical-site infection (...) in clean-contaminated surgery.The systematic review identified six eligible studies, containing 5031 patients. Chlorhexidine reduced postoperative surgical-site infection compared with povidone-iodine (pooled odds ratio 0.68, 95 per cent confidence interval 0.50 to 0.94; P = 0.019) .Chlorhexidine should be used preferentially for preoperative antisepsis in clean-contaminated surgery.Copyright © 2010 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.

2011 EvidenceUpdates

122. The effect of a chlorhexidine-based surgical lubricant during pelvic examination on the detection of group B Streptococcus (PubMed)

The effect of a chlorhexidine-based surgical lubricant during pelvic examination on the detection of group B Streptococcus The objective of the study was to estimate whether surgical lubricant used during pelvic examination alters the detection of group B Streptococcus (GBS).We conducted a prospective cohort study of patients undergoing GBS screening at the prenatal clinics of a New York City public hospital. Two specimens were collected from each patient, before and after a pelvic examination

2010 EvidenceUpdates

123. Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. (PubMed)

Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine.We randomly assigned adults undergoing clean-contaminated surgery in six hospitals to preoperative skin (...) preparation with either chlorhexidine-alcohol scrub or povidone-iodine scrub and paint. The primary outcome was any surgical-site infection within 30 days after surgery. Secondary outcomes included individual types of surgical-site infections.A total of 849 subjects (409 in the chlorhexidine-alcohol group and 440 in the povidone-iodine group) qualified for the intention-to-treat analysis. The overall rate of surgical-site infection was significantly lower in the chlorhexidine-alcohol group than

2010 NEJM

124. Herbal mouthwash more effective than OTC mouthwash and may be as effective as chlorhexidine rinse.

Herbal mouthwash more effective than OTC mouthwash and may be as effective as chlorhexidine rinse. UTCAT479, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Herbal mouthwash more effective than OTC mouthwash and may be as effective as chlorhexidine rinse Clinical Question Can herbal mouthwash be as effective as OTC mouthwash at preventing gum disease? Clinical Bottom Line In vivo, both herbal mouth and gum therapy (...) and Peridex were significantly more effective at inhibiting microbial growth than Listerine. In vitro, Chlorhexidine rinse was the most effective; herbal rinse was less effective than chlorhexidine but more effective than an essential oil rinse. (See Comments on the CAT below) Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Haffajee/2008 120 inoculated plates In vitro study Key results In vitro, Chlorhexidine

2010 UTHSCSA Dental School CAT Library

125. Chlorhexidine Applications Improve Oral Health of Patients with Down Syndrome

Chlorhexidine Applications Improve Oral Health of Patients with Down Syndrome UTCAT466, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Chlorhexidine Applications Improve Oral Health of Patients with Down Syndrome Clinical Question In a patient with Down Syndrome and poor oral hygiene, will chlorhexidine applications prove more successful at increasing the patient’s overall oral health versus no treatment? Clinical (...) Bottom Line Chlorhexidine applications in a 2% sustained-delivery dosage form along with rinses with 0.2% chlorhexidine mouthwash and brushing with 1% chlorhexidine gel improve the oral health of patients with Down Syndrome. (See Comments on the CAT below) Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Stabholz/1991 30 subjects with Down Syndrome; 10 received placebo, 10 received chlorhexidine solution

2010 UTHSCSA Dental School CAT Library

126. Randomised controlled trial: Preoperative skin cleansing with chlorhexidine-alcohol reduces surgical site infection after clean-contaminated surgery compared with povidone-iodine

Randomised controlled trial: Preoperative skin cleansing with chlorhexidine-alcohol reduces surgical site infection after clean-contaminated surgery compared with povidone-iodine Preoperative skin cleansing with chlorhexidine-alcohol reduces surgical site infection after clean-contaminated surgery compared with povidone-iodine | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser (...) at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Preoperative skin cleansing with chlorhexidine-alcohol reduces

2010 Evidence-Based Nursing

127. Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery

Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery Systematic review and meta-analysis of preoperative antisepsis with chlorhexidine versus povidone-iodine in clean-contaminated surgery Noorani A, Rabey N, Walsh SR, Davies RJ CRD summary Preoperative cleansing of the skin (...) with chlorhexidine had significant benefits compared with povidone iodine in reducing postoperative surgical site infections after clean-contaminated surgery. The poor quality of the included studies and some methodological flaws mean that the results should be interpreted with caution and that the reliability of the authors' conclusions is not clear. Authors' objectives To determine whether povidone-iodine or chlorhexidine was the preferred agent for cleansing of skin prior to clean-contaminated surgery

2010 DARE.

128. Systematic review and cost analysis comparing use of chlorhexidine with use of iodine for preoperative skin antisepsis to prevent surgical site infection

Systematic review and cost analysis comparing use of chlorhexidine with use of iodine for preoperative skin antisepsis to prevent surgical site infection Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 NHS Economic Evaluation Database.

129. Chlorhexidine gel reduces incidence of alveolar osteitis after extraction of the mandibular third molars. (PubMed)

Chlorhexidine gel reduces incidence of alveolar osteitis after extraction of the mandibular third molars. A randomised, prospective clinical trial with parallel groups was carried out in a single centre.The experimental (gel) group (n=41) applied a bioadhesive 0.2% chlorhexidine gel to the wound during the first postoperative week and a control (rinse) group (n=32) used a 0.12% (v/v) chlorhexidine mouthrinse during the first week following third molar extraction. Patients were evaluated (...) on the third and seventh postoperative day.Alveolar osteitis was evaluated according to Blum's criteria..A 70% decrease in postoperative alveolar osteitis in the gel group (P 0.04) was observed. The rinse group had 25% incidence of postoperative alveolar osteitis, whereas the gel group had 7.5%. T equates to a number needed to treat of six (95% confidence interval, 3-144).It was concluded that the topical application of bioadhesive chlorhexidine gel to the surgical wound during the postoperative week may

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2009 Evidence-based dentistry

130. Oropharyngeal cleansing with 0.2% chlorhexidine for prevention of nosocomial pneumonia in critically ill patients: an open-label randomized trial with 0.01% potassium permanganate as control (PubMed)

Oropharyngeal cleansing with 0.2% chlorhexidine for prevention of nosocomial pneumonia in critically ill patients: an open-label randomized trial with 0.01% potassium permanganate as control Oral cleansing with chlorhexidine decreases the incidence of nosocomial pneumonia in patients after cardiac surgery. However, evidence of its benefit in ICU patients is conflicting.Patients admitted to the ICU of an Indian tertiary care teaching hospital were randomized to twice-daily oropharyngeal (...) cleansing with 0.2% chlorhexidine or 0.01% potassium permanganate (control) solution. Effects on the incidence of nosocomial pneumonia during ICU stay (primary outcome) and length of ICU stay and in-hospital mortality (secondary outcomes) were studied.Five hundred twelve patients were randomized to either the chlorhexidine group (n = 250) or the control group (n = 262). Of the 471 subjects who completed the protocol, nosocomial pneumonia developed in 16 of 224 subjects (7.1%) in the chlorhexidine group

2009 EvidenceUpdates

131. Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. (PubMed)

Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial. Use of a chlorhexidine gluconate-impregnated sponge (CHGIS) in intravascular catheter dressings may reduce catheter-related infections (CRIs). Changing catheter dressings every 3 days may be more frequent than necessary.To assess superiority of CHGIS dressings regarding the rate of major CRIs (clinical sepsis with or without

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2009 JAMA

132. Chlorhexidine maternal-vaginal and neonate body wipes in sepsis and vertical transmission of pathogenic bacteria in South Africa: a randomised, controlled trial. (PubMed)

Chlorhexidine maternal-vaginal and neonate body wipes in sepsis and vertical transmission of pathogenic bacteria in South Africa: a randomised, controlled trial. About 500,000 sepsis-related deaths per year arise in the first 3 days of life. On the basis of results from non-randomised studies, use of vaginal chlorhexidine wipes during labour has been proposed as an intervention for the prevention of early-onset neonatal sepsis in developing countries. We therefore assessed the efficacy (...) of chlorhexidine in early-onset neonatal sepsis and vertical transmission of group B streptococcus.In a trial in Soweto, South Africa, 8011 women (aged 12-51 years) were randomly assigned in a 1:1 ratio to chlorhexidine vaginal wipes or external genitalia water wipes during active labour, and their 8129 newborn babies were assigned to full-body (intervention group) or foot (control group) washes with chlorhexidine at birth, respectively. In a subset of mothers (n=5144), we gathered maternal lower vaginal swabs

2009 Lancet

133. Chlorhexidine and Caries Incidence In School-Based Programs

Chlorhexidine and Caries Incidence In School-Based Programs UTCAT452, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Chlorhexidine Does not Reduce Caries Incidence In School-Based Programs Compared with Regular Fluoride Use and Oral Hygiene Clinical Question In school-based programs with children and adolescents, is it more beneficial to use Chlorhexidine to prevent dental caries compared to fluoride treatment (...) ? Clinical Bottom Line In school-based programs, repeated application of chlorhexidine does not lower the caries incidence in young individuals any more than regular fluoride use and oral hygiene practices. (See Comments on the CAT below) Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Ersin/2008 149 eleven to thirteen year olds with high caries risk and low caries incidence Randomized Clinical Trial Key

2009 UTHSCSA Dental School CAT Library

134. Preoperative whole-body bathing with chlorhexidine gluconate for prevention of surgical site infection

Preoperative whole-body bathing with chlorhexidine gluconate for prevention of surgical site infection Preoperative whole-body bathing with chlorhexidine gluconate for prevention of surgical site infection Preoperative whole-body bathing with chlorhexidine gluconate for prevention of surgical site infection Citation Preoperative whole-body bathing with chlorhexidine gluconate for prevention of surgical site infection. Lansdale: HAYES, Inc.. 2009 Authors' objectives

Surgical site infections (...) (SSIs) occur in approximately 2.0% to 3.5% of surgeries and have potentially serious consequences including death. These infections prolong hospitalization and increase costs. Whole-body bathing with an antiseptic such as chlorhexidine gluconate is widely employed before surgery to decrease the number of bacteria on the skin, in an attempt to decrease the incidence of SSIs. Despite their widespread use, it has not been conclusively shown that bathing or showering with these antiseptics actually

2009 Health Technology Assessment (HTA) Database.

135. Intravascular catheter dressings with chlorhexidine-impregnated sponges reduced infections in the ICU

Intravascular catheter dressings with chlorhexidine-impregnated sponges reduced infections in the ICU Intravascular catheter dressings with chlorhexidine-impregnated sponges reduced infections in the ICUCommentary | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Intravascular catheter dressings with chlorhexidine-impregnated sponges reduced infections in the ICUCommentary Article Text Treatment Intravascular catheter dressings

2009 Evidence-Based Nursing

136. Decontamination of the nasopharynx and oropharynx with chlorhexidine reduced nosocomial infections in cardiac surgery

Decontamination of the nasopharynx and oropharynx with chlorhexidine reduced nosocomial infections in cardiac surgery Decontamination of the nasopharynx and oropharynx with chlorhexidine reduced nosocomial infections in cardiac surgery | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Decontamination of the nasopharynx and oropharynx with chlorhexidine reduced nosocomial infections in cardiac surgery Article Text Treatment Decontamination

2008 Evidence-Based Nursing

137. Use of chlorhexidine varnishes in preventing and treating periodontal disease: a review of the literature

Use of chlorhexidine varnishes in preventing and treating periodontal disease: a review of the literature Use of chlorhexidine varnishes in preventing and treating periodontal disease: a review of the literature Use of chlorhexidine varnishes in preventing and treating periodontal disease: a review of the literature Puig Silla M, Montiel Company J M, Almerich Silla, J M CRD summary The authors concluded that chlorhexidine varnish may be of benefit for chronic gingivitis and that high (...) -concentration varnish may help reduce pocket depth following scaling and root planing for chronic periodontitis. Poor reporting of review methods and failure to assess study validity or quantify effect sizes meant that the conclusions may need to be regarded with caution. Authors' objectives To evaluate the effectiveness of chlorhexidine varnishes for preventing and treating periodontal disease. Searching PubMed, EMBASE and The Cochrane Library were searched in June 2007. Search terms were reported. Study

2008 DARE.

138. Efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalis: a systematic review

Efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalis: a systematic review Efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalis: a systematic review Efficacy of sodium hypochlorite and chlorhexidine against Enterococcus faecalis: a systematic review Estrela C, Silva JA, de Alencar AH, Leles CR, Decurcio DA CRD summary This review concluded that sodium hypochlorite had low ability to eliminate Enterococcus faecalis when evaluated by polymerase (...) chain reaction or by culture. It included small studies with uncertain validity and the authors' conclusions should be treated with caution. Authors' objectives To review the findings on the antibacterial efficacy of sodium hypochlorite or chlorhexidine against Enterococcus faecalis in endodontic infection. Searching English-language studies were identified through a search of MEDLINE, EMBASE, Cochrane Oral Health Group's Trials Register, and the Cochrane Central Register of Controlled Trials

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2008 DARE.

139. Oral decontamination with chlorhexidine reduced ventilator associated pneumonia in patients needing mechanical ventilation for 48 hours

Oral decontamination with chlorhexidine reduced ventilator associated pneumonia in patients needing mechanical ventilation for 48 hours Oral decontamination with chlorhexidine reduced ventilator associated pneumonia in patients needing mechanical ventilation for ⩾48 hours | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please (...) see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Oral decontamination with chlorhexidine reduced ventilator associated pneumonia in patients needing mechanical

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2008 Evidence-Based Nursing

140. Oral Decontamination with Chlorhexidine Reduces the Incidence of Ventilator-associated Pneumonia.

Oral Decontamination with Chlorhexidine Reduces the Incidence of Ventilator-associated Pneumonia. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2007 PedsCCM Evidence-Based Journal Club