Latest & greatest articles for chronic kidney disease

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Top results for chronic kidney disease

421. Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: a position statement

Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: a position statement Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: a position statement | The Medical Journal of Australia mja-search search Use the for more specific terms. Title contains Body contains Date range from Date range to Article type Author's surname Volume First page doi: 10.5694/mja__.______ Search Reset  close Individual Login Purchase options Connect (...) person_outline Login keyboard_arrow_down Individual Login Purchase options menu search Advertisement close Chronic kidney disease and automatic reporting of estimated glomerular filtration rate: a position statement Timothy H Mathew, The Australasian Creatinine Consensus Working Group Med J Aust 2005; 183 (3): 138-141. || doi: 10.5694/j.1326-5377.2005.tb06958.x Published online: 1 August 2005 Topics Abstract The systematic staging of chronic kidney disease (CKD) by glomerular filtration measurement

2005 MJA Clinical Guidelines

422. Apolipoprotein E and progression of chronic kidney disease. (PubMed)

Apolipoprotein E and progression of chronic kidney disease. Apolipoprotein E (APOE) genetic variation has been implicated in diabetic nephropathy with the epsilon2 allele increasing and the epsilon4 allele decreasing risk. APOE allelic associations with chronic kidney disease beyond diabetic nephropathy are unknown, with no studies reported in high-risk African American populations.To quantify the risk of chronic kidney disease progression associated with APOE in a population-based study (...) including white, African American, diabetic, and nondiabetic individuals.Prospective follow-up (through January 1, 2003) of Atherosclerosis Risk in Communities (ARIC) study participants, including 3859 African American and 10,661 white adults aged 45 to 64 years without severe renal dysfunction at baseline in 1987-1989, sampled from 4 US communities.Incident chronic kidney disease progression, defined as hospitalization or death with kidney disease or increase in serum creatinine level of 0.4 mg/dL (35

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2005 JAMA

423. Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. (PubMed)

Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. Elderly persons with chronic kidney disease have substantial risk for cardiovascular mortality, but the relative importance of traditional and novel risk factors is unknown.To compare traditional and novel risk factors as predictors of cardiovascular mortality.A total of 5808 community-dwelling persons aged 65 years or older living in 4 communities in the United States participated (...) in the Cardiovascular Health Study cohort. Participants were initially recruited from 1989 to June 1990; an additional 687 black participants were recruited in 1992-1993. The average length of follow-up in this longitudinal study was 8.6 years.Cardiovascular mortality among those with and without chronic kidney disease. Chronic kidney disease was defined as an estimated glomerular filtration rate of less than 60 mL/min per 1.73 m2.Among the participants, 1249 (22%) had chronic kidney disease at baseline

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2005 JAMA

424. Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. (PubMed)

Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. The National Kidney Foundation has advocated the use of the abbreviated Modification of Diet in Renal Disease (MDRD) equation to estimate glomerular filtration rate (GFR) from serum creatinine measurements in clinical laboratories. However, healthy persons were not included in the development of the MDRD equation.To assess the accuracy of the MDRD equation in patients (...) with chronic kidney disease compared with healthy persons and to develop a new equation that uses both patients with chronic kidney disease and healthy persons.Cross-sectional study.The Mayo Clinic, a tertiary-care medical center.Consecutive patients (n = 320) who had an iothalamate clearance test specifically for chronic kidney disease evaluation and consecutive healthy persons (n = 580) who had an iothalamate clearance test specifically for kidney donor evaluation.Serum creatinine levels, GFR

2004 Annals of Internal Medicine

425. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. (PubMed)

Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. End-stage renal disease substantially increases the risks of death, cardiovascular disease, and use of specialized health care, but the effects of less severe kidney dysfunction on these outcomes are less well defined.We estimated the longitudinal glomerular filtration rate (GFR) among 1,120,295 adults within a large, integrated system of health care delivery in whom serum creatinine had been measured (...) between 1996 and 2000 and who had not undergone dialysis or kidney transplantation. We examined the multivariable association between the estimated GFR and the risks of death, cardiovascular events, and hospitalization.The median follow-up was 2.84 years, the mean age was 52 years, and 55 percent of the group were women. After adjustment, the risk of death increased as the GFR decreased below 60 ml per minute per 1.73 m2 of body-surface area: the adjusted hazard ratio for death was 1.2

2004 NEJM

426. The metabolic syndrome and chronic kidney disease in U.S. adults. (PubMed)

The metabolic syndrome and chronic kidney disease in U.S. adults. The metabolic syndrome is a common risk factor for cardiovascular disease.To examine the association between the metabolic syndrome and risk for chronic kidney disease and microalbuminuria.Cross-sectional study.The Third National Health and Nutrition Examination Survey.Participants 20 years of age or older were studied in the chronic kidney disease (n = 6217) and microalbuminuria (n = 6125) analyses.The metabolic syndrome (...) was defined as the presence of 3 or more of the following risk factors: elevated blood pressure, low high-density lipoprotein cholesterol level, high triglyceride level, elevated glucose level, and abdominal obesity. Chronic kidney disease was defined as a glomerular filtration rate less than 60 mL/min per 1.73 m2, and microalbuminuria was defined as a urinary albumin-creatinine ratio of 30 to 300 mg/g.The multivariate-adjusted odds ratios of chronic kidney disease and microalbuminuria in participants

2004 Annals of Internal Medicine

427. The prevalence of nontraditional risk factors for coronary heart disease in patients with chronic kidney disease. (PubMed)

The prevalence of nontraditional risk factors for coronary heart disease in patients with chronic kidney disease. Risk for coronary heart disease is high among patients with chronic kidney disease.To compare the prevalence of low apolipoprotein A1 levels and elevated apolipoprotein B, plasma fibrinogen, lipoprotein(a), homocysteine, and C-reactive protein levels by estimated glomerular filtration rate (GFR).Cross-sectional study.Third National Health and Nutrition Examination survey.12 547 (...) homocysteine level of at least 15 micromol/L, and a C-reactive protein level of at least 10.0 mg/L for participants with chronic kidney disease compared with those with a GFR of at least 90 mL/min per 1.73 m2 or greater were 1.92 (95% CI, 1.02 to 3.63), 1.82 (CI, 1.06 to 3.13), 1.74 (CI, 1.35 to 2.24), 8.23 (CI, 5.00 to 13.6), and 1.93 (CI, 1.33 to 2.81), respectively.Levels of apolipoprotein A1 are decreased and levels of homocysteine, lipoprotein(a), fibrinogen, and C-reactive protein are increased among

2004 Annals of Internal Medicine

428. Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials

Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials Alonso A, Lau J, Jaber B L, Weintraub (...) A, Sarnak M J CRD summary This systematic review concluded that N-acetylcysteine is effective in the prevention of renal contrast nephropathy in patients with pre-existing chronic kidney disease. Although there were some limitations of the review in terms of measures taken to minimise reviewer bias and possible statistical diversity, overall, the authors' conclusions appear reliable. Authors' objectives To assess the effects of N-acetylcysteine (NAC) in the prevention of renal contrast nephropathy (RCN

2004 DARE.

429. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. (PubMed)

National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Chronic kidney disease is a worldwide public health problem with an increasing incidence and prevalence, poor outcomes, and high cost. Outcomes of chronic kidney disease include not only kidney failure but also complications of decreased kidney function and cardiovascular disease. Current evidence suggests that some of these adverse outcomes can be prevented or delayed (...) by early detection and treatment. Unfortunately, chronic kidney disease is underdiagnosed and undertreated, in part as a result of lack of agreement on a definition and classification of its stages of progression. Recent clinical practice guidelines by the National Kidney Foundation 1) define chronic kidney disease and classify its stages, regardless of underlying cause, 2) evaluate laboratory measurements for the clinical assessment of kidney disease, 3) associate the level of kidney function

2003 Annals of Internal Medicine

430. The timing of specialist evaluation in chronic kidney disease and mortality. (PubMed)

The timing of specialist evaluation in chronic kidney disease and mortality. Care for chronic renal failure involves management of complications and preparation for possible dialysis. Patients often are not evaluated by nephrologists in a timely manner.To identify factors associated with late evaluation by a nephrologist and to assess whether late evaluation is associated with worse survival once patients develop end-stage renal disease (ESRD).National prospective cohort study.81 dialysis (...) characteristics, and socioeconomic status in Cox proportional hazards regression analysis. After additional adjustment for such factors as the presence and severity of comorbid conditions, the association remained graded (hazard ratio, 1.2 [CI, 0.73 to 1.82] for patients evaluated at an intermediate point and 1.6 [CI, 1.04 to 2.39] for those evaluated late).Late evaluation of patients with chronic renal failure by a nephrologist is associated with greater burden and severity of comorbid disease, black

2002 Annals of Internal Medicine