Latest & greatest articles for chronic pain

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on chronic pain or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on chronic pain and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

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Top results for chronic pain

101. Cannabis for management of chronic cancer-related pain: a systematic review and meta-analysis

Cannabis for management of chronic cancer-related pain: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external

2019 PROSPERO

102. The comparative effectiveness of physical exercise interventions in individuals with chronic neck pain: protocol for a network meta-analysis

The comparative effectiveness of physical exercise interventions in individuals with chronic neck pain: protocol for a network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

103. The clinical efficacy of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain: a protocol for a meta-analysis of randomized controlled trials (RCTs)

The clinical efficacy of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain: a protocol for a meta-analysis of randomized controlled trials (RCTs) Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

104. The efficacy, safety and tolerability of antidepressants, for patients with chronic low back pain and without depression - a systematic review and network meta-analysis

The efficacy, safety and tolerability of antidepressants, for patients with chronic low back pain and without depression - a systematic review and network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

105. The efficacy of osteopathic manual treatment (OMT) in the reduction of pain severity, functional improvement and return to work in chronic non-cancer pain patients - meta-analysis and systematic review

The efficacy of osteopathic manual treatment (OMT) in the reduction of pain severity, functional improvement and return to work in chronic non-cancer pain patients - meta-analysis and systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears

2019 PROSPERO

106. The association between spousal reactions to chronic pain and pain-related patient outcomes: a systematic review

The association between spousal reactions to chronic pain and pain-related patient outcomes: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated

2019 PROSPERO

107. Associations of psycho-social resources with changes in chronic pain: a systematic review

Associations of psycho-social resources with changes in chronic pain: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites

2019 PROSPERO

108. Exploring the relationship between chronic pain and cortisol levels in subjects with osteoarthritis: results from a systematic review of the literature

Exploring the relationship between chronic pain and cortisol levels in subjects with osteoarthritis: results from a systematic review of the literature Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2019 PROSPERO

109. Exercise-based interventions in multidisciplinary rehabilitation for reducing fear avoidance in non-specific chronic low back pain: a systematic review and meta-analysis

Exercise-based interventions in multidisciplinary rehabilitation for reducing fear avoidance in non-specific chronic low back pain: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

110. Enablers and barriers of people with chronic musculoskeletal pain for engaging in remotely-delivered interventions: a qualitative systematic review and meta-synthesis

Enablers and barriers of people with chronic musculoskeletal pain for engaging in remotely-delivered interventions: a qualitative systematic review and meta-synthesis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

111. A systematic review of the prevalence of prescription opioid dependence in patients with chronic non-cancer pain (CNCP) receiving treatment with opioid painkillers

A systematic review of the prevalence of prescription opioid dependence in patients with chronic non-cancer pain (CNCP) receiving treatment with opioid painkillers Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

112. Nonopioid pharmacologic treatments for chronic pain

Nonopioid pharmacologic treatments for chronic pain Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith

2019 PROSPERO

113. Health-related quality of life in patients with chronic low back pain compared to controls: a systematic review and meta-analysis protocol of case-control studies

Health-related quality of life in patients with chronic low back pain compared to controls: a systematic review and meta-analysis protocol of case-control studies Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

114. Multimodal intervention including rehabilitation exercise for older patients with chronic musculoskeletal pain: a systematic review with meta-analyses of randomized controlled trials

Multimodal intervention including rehabilitation exercise for older patients with chronic musculoskeletal pain: a systematic review with meta-analyses of randomized controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility

2019 PROSPERO

115. The lived experiences of informal caregivers/significant others of people with chronic musculoskeletal pain: a systematic review and meta-ethnography

The lived experiences of informal caregivers/significant others of people with chronic musculoskeletal pain: a systematic review and meta-ethnography Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2019 PROSPERO

116. Self-compassion in chronic pain: a systematic review

Self-compassion in chronic pain: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith

2019 PROSPERO

117. Relative efficacy and acceptability of pharmacological and non-pharmacological interventions for chronic low back pain: a protocol for a systematic review and network meta-analysis

Relative efficacy and acceptability of pharmacological and non-pharmacological interventions for chronic low back pain: a protocol for a systematic review and network meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility

2019 PROSPERO

118. Quality of spinal movement in people with chronic neck pain

Quality of spinal movement in people with chronic neck pain Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr

2019 PROSPERO

119. The effectiveness of a caregiver intervention to improve patient clinical outcomes and reduce caregiver burden and distress for people with chronic musculoskeletal pain: a systematic review

The effectiveness of a caregiver intervention to improve patient clinical outcomes and reduce caregiver burden and distress for people with chronic musculoskeletal pain: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility

2019 PROSPERO

120. Efficacy and safety of long-term use of muscle relaxants used for chronic pain: a systematic review

Efficacy and safety of long-term use of muscle relaxants used for chronic pain: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external

2019 PROSPERO