Latest & greatest articles for constipation

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on constipation or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on constipation and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for constipation

181. What is the role of stimulant laxatives in the management of childhood constipation and soiling?. (PubMed)

What is the role of stimulant laxatives in the management of childhood constipation and soiling?. Constipation is extremely common in childhood and may lead to overflow soiling/encopresis. Standard treatment of the more severe case is to empty the bowels of impacted faeces by the use of oral or rectal laxatives and then maintain regular bowel movements by the continuation of osmotic and stimulant laxatives.The objective of the review was to determine the effect of stimulant laxative treatment (...) in children with chronic constipation who may also suffer from soiling / encopresis.The Cochrane database of randomised controlled trials was searched. Additional citations were sought by hand searching of paediatric journals and from contact with known professionals in the field.All identified randomised controlled trials (RCTs) which compare the administering of stimulant laxatives to children with either placebo or alternative treatment.No trials were found that met the selection criteria.No trials

2001 Cochrane

182. Dietary fiber for constipation in older adults: a systematic review

Dietary fiber for constipation in older adults: a systematic review Dietary fiber for constipation in older adults: a systematic review Dietary fiber for constipation in older adults: a systematic review Kenny K A, Skelly J M Authors' objectives To assess the effectiveness of dietary fibre for constipation in older adults. Searching MEDLINE (from 1966 to present) and CINAHL (from 1982 to present) were searched for publications in the English language, using the terms 'constipation' and 'dietary (...) of magnesia, enemas, and suppositories. Participants included in the review Older patients (aged 60 years or over) with constipation were eligible. The included participants were either in hospital or long-stay care settings. No definition of constipation was specified as an inclusion criteria for the review. Patients with irritable bowel syndrome or diverticular disease were excluded. Outcomes assessed in the review Trials that quantified outcomes for at least one measure of bowel function were eligible

2001 DARE.

183. Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial. (PubMed)

Methylnaltrexone for reversal of constipation due to chronic methadone use: a randomized controlled trial. Constipation is the most common chronic adverse effect of opioid pain medications in patients who require long-term opioid administration, such as patients with advanced cancer, but conventional measures for ameliorating constipation often are insufficient.To evaluate the efficacy of methylnaltrexone, the first peripheral opioid receptor antagonist, in treating chronic methadone-induced (...) , and no significant adverse effects were reported by the subjects during the study.Our data demonstrate that intravenous methylnaltrexone can induce laxation and reverse slowing of oral cecal-transit time in subjects taking high opioid dosages. Low-dosage methylnaltrexone may have clinical utility in managing opioid-induced constipation.

2000 JAMA

184. How useful is docusate in patients at risk for constipation: a systematic review of the evidence in the chronically ill

How useful is docusate in patients at risk for constipation: a systematic review of the evidence in the chronically ill How useful is docusate in patients at risk for constipation: a systematic review of the evidence in the chronically ill How useful is docusate in patients at risk for constipation: a systematic review of the evidence in the chronically ill Hurdon V, Viola R, Schroder C Authors' objectives To evaluate the effectiveness of docusate for constipation in chronic illness. Searching (...) Searches were conducted of the following sources for articles published after 1940: Cochrane Database of Systematic Reviews, DARE (Issue 3) and Cochrane Controlled Trials Register using the terms 'constipation', 'dioctyl', and 'docusate'; MEDLINE (1966 to April 1997) and CINAHL (1982 to April 1997) using the terms 'constipation' and 'docusate' and 'dioctyl', both as subject headings and textwords, 'doxidan' as a textword, and 'docusate' via its MEDLINE drug registry number. Floating sub-headings

2000 DARE.

185. Abdominal massage therapy for chronic constipation: a systematic review of controlled clinical trials

Abdominal massage therapy for chronic constipation: a systematic review of controlled clinical trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

1999 DARE.

186. Intolerance of cow's milk and chronic constipation in children. (PubMed)

Intolerance of cow's milk and chronic constipation in children. Chronic diarrhea is the most common gastrointestinal symptom of intolerance of cow's milk among children. On the basis of a prior open study, we hypothesized that intolerance of cow's milk can also cause severe perianal lesions with pain on defecation and consequent constipation in young children.We performed a double-blind, crossover study comparing cow's milk with soy milk in 65 children (age range, 11 to 72 months) with chronic (...) constipation (defined as having one bowel movement every 3 to 15 days). All had been referred to a pediatric gastroenterology clinic and had previously been treated with laxatives without success; 49 had anal fissures and perianal erythema or edema. After 15 days of observation, the patients received cow's milk or soy milk for two weeks. After a one-week washout period, the feedings were reversed. A response was defined as eight or more bowel movements during a treatment period.Forty-four of the 65

1998 NEJM

187. The treatment of chronic constipation in adults: a systematic review

The treatment of chronic constipation in adults: a systematic review The treatment of chronic constipation in adults: a systematic review The treatment of chronic constipation in adults: a systematic review Tramonte S M, Brand M B, Mulrow C D, Amato M G, O'Keefe M E, Ramirez G Authors' objectives To evaluate whether laxatives and fibre therapy improve symptoms and bowel movement frequency in adults with chronic constipation. Searching The following sources were searched: MEDLINE from 1966 (...) included in the review were psyllium, ispaghula, bran, prucara, lactulose, lactitol, propylethylene glycol, docusate sodium, docusate calcium, cisapride, senna, agiolax, lunelax, calcium polycarbophil, methylcellulose, magnesium hydroxide, laxamucil, sorbitol, dorbanex and sodium picosulphate. Participants included in the review Patients with a constipation for a minimum of two weeks, whose constipation was treated for a minimum of one week. Patients from special populations, such as peripartum

1997 DARE.

188. Biofeedback training in treatment of childhood constipation: a randomised controlled study. (PubMed)

Biofeedback training in treatment of childhood constipation: a randomised controlled study. Because abnormal defaecation dynamics, which can be modified by biofeedback, are considered to be the underlying problem in constipation, biofeedback training may be a useful treatment for constipation. This treatment has mainly been studied in uncontrolled trials. We evaluated defaecation dynamics and clinical outcome in chronically constipated children in a randomised study comparing conventional (...) treatment and conventional treatment with biofeedback training.Patients, 5 to 16 years old, were referred to the Academic Medical Center in Amsterdam by general practitioners, school doctors, paediatricians, and psychiatrists. They had to fulfil at least two of four criteria for paediatric constipation and were included if they had been treated medically for at least one month before randomisation. Patients had a medical history, abdominal and rectal examination, and anorectal manometry at the start

1996 Lancet

189. Chronic constipation in long stay elderly patients: a comparison of lactulose and a senna-fibre combination. (Full text)

Chronic constipation in long stay elderly patients: a comparison of lactulose and a senna-fibre combination. To compare the efficacy and cost effectiveness of a senna-fibre combination and lactulose in treating constipation in long stay elderly patients.Randomised, double blind, cross over study.Four hospitals in Northern Ireland, one hospital in England, and two nursing homes in England.77 elderly patients with a history of chronic constipation in long term hospital or nursing home care.A (...) effective and well tolerated for chronic constipation in long stay elderly patients. The senna-fibre combination was significantly more effective than lactulose at a lower cost.

1993 BMJ PubMed