Latest & greatest articles for corticosteroids

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Top results for corticosteroids

761. Long-term inhaled corticosteroids in preschool children at high risk for asthma. (PubMed)

Long-term inhaled corticosteroids in preschool children at high risk for asthma. It is unknown whether inhaled corticosteroids can modify the subsequent development of asthma in preschool children at high risk for asthma.We randomly assigned 285 participants two or three years of age with a positive asthma predictive index to treatment with fluticasone propionate (at a dose of 88 mug twice daily) or masked placebo for two years, followed by a one-year period without study medication (...) . The primary outcome was the proportion of episode-free days during the observation year.During the observation year, no significant differences were seen between the two groups in the proportion of episode-free days, the number of exacerbations, or lung function. During the treatment period, as compared with placebo use, use of the inhaled corticosteroid was associated with a greater proportion of episode-free days (P=0.006) and a lower rate of exacerbations (P<0.001) and of supplementary use

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2006 NEJM Controlled trial quality: predicted high

762. Intermittent inhaled corticosteroids in infants with episodic wheezing. (PubMed)

Intermittent inhaled corticosteroids in infants with episodic wheezing. We hypothesized that asthma is preceded by a stage of recurrent episodes of wheezing during the first years of life and that inhaled corticosteroid therapy during symptomatic episodes in this early phase may delay progression to persistent wheezing.We assigned one-month-old infants to treatment with two-week courses of inhaled budesonide (400 mug per day) or placebo, initiated after a three-day episode of wheezing (...) and bone mineral density were not affected by treatment.Intermittent inhaled corticosteroid therapy had no effect on the progression from episodic to persistent wheezing and no short-term benefit during episodes of wheezing in the first three years of life. (ClinicalTrials.gov number, NCT00234390.).Copyright 2006 Massachusetts Medical Society.

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2006 NEJM Controlled trial quality: predicted high

763. Review: adults who require inhaled corticosteroids benefit from a moderate starting dose

Review: adults who require inhaled corticosteroids benefit from a moderate starting dose Review: adults who require inhaled corticosteroids benefit from a moderate starting dose | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: adults who require inhaled corticosteroids benefit from a moderate starting dose Article Text Therapeutics Review: adults who require inhaled corticosteroids benefit from a moderate starting dose Free Frank

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2005 Evidence-Based Medicine

764. Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control

Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Doubling the dose of inhaled corticosteroids during asthma deterioration did not improve asthma control Article Text Therapeutics Doubling the dose of inhaled corticosteroids

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2005 Evidence-Based Medicine

765. Oral corticosteroids for stable chronic obstructive pulmonary disease. (PubMed)

Oral corticosteroids for stable chronic obstructive pulmonary disease. Chronic obstructive pulmonary disease (COPD) is a common chronic lung disorder, usually related to cigarette smoking, representing a major and increasing cause of morbidity and mortality. It is defined "as a disease state characterized by airflow limitation that is not fully reversible. The airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles (...) or gases". The use of corticosteroids for their anti-inflammatory effects has been suggested.To assess the effects of oral corticosteroids on the health status of patients with stable COPD.Searches of the Cochrane Airways Group Specialised Register and MEDLINE were carried out in December 2003 and 2004. Review articles and bibliographies were searched.Randomised controlled prospective studies in adults with stable COPD ( post-bronchodilator FEV1 <80% of predicted, FEV1/FVC <70%) and a history

2005 Cochrane

766. Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids

Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Smokers and ex-smokers with chronic stable asthma did not respond to high dose oral corticosteroids Article Text Therapeutics Smokers and ex-smokers with chronic stable asthma did

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2005 Evidence-Based Medicine

767. Review: long acting B2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease

Review: long acting B2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Review: long acting β2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: long acting β2 agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Article Text Treatment Review

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2005 Evidence-Based Nursing

768. Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months. (PubMed)

Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months. MRC CRASH is a randomised controlled trial (ISRCTN74459797) of the effect of corticosteroids on death and disability after head injury. We randomly allocated 10,008 adults with head injury and a Glasgow Coma Scale score of 14 or less, within 8 h of injury, to a 48-h infusion of corticosteroid (methylprednisolone) or placebo. Data at 6 months were (...) obtained for 9673 (96.7%) patients. The risk of death was higher in the corticosteroid group than in the placebo group (1248 [25.7%] vs 1075 [22.3%] deaths; relative risk 1.15, 95% CI 1.07-1.24; p=0.0001), as was the risk of death or severe disability (1828 [38.1%] vs 1728 [36.3%] dead or severely disabled; 1.05, 0.99-1.10; p=0.079). There was no evidence that the effect of corticosteroids differed by injury severity or time since injury. These results lend support to our earlier conclusion

2005 Lancet Controlled trial quality: predicted high

769. Review: inhaled corticosteroids slow the progression of airflow limitation in COPD

Review: inhaled corticosteroids slow the progression of airflow limitation in COPD Review: inhaled corticosteroids slow the progression of airflow limitation in COPD | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional (...) accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: inhaled corticosteroids slow the progression of airflow limitation in COPD Article Text Therapeutics Review: inhaled corticosteroids slow the progression of airflow limitation in COPD Free Michael Greenstone , MD, FRCP

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2005 Evidence-Based Medicine

770. Review: long acting ß2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease

Review: long acting ß2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Review: long acting β2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: long acting β2-agonists and inhaled corticosteroids reduce exacerbations in chronic obstructive pulmonary disease Article Text

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2005 Evidence-Based Medicine

771. Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis

Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: adjuvant corticosteroid therapy reduces death, hearing loss, and neurological sequelae in bacterial meningitis Article Text Therapeutics Review

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2005 Evidence-Based Medicine

772. Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control study. (PubMed)

Use of inhaled corticosteroids during pregnancy and risk of pregnancy induced hypertension: nested case-control study. To determine whether the use of inhaled corticosteroids during pregnancy increases the risk of pregnancy induced hypertension and pre-eclampsia among asthmatic women.Nested case-control study.Three administrative health databases from Quebec: RAMQ, MED-ECHO, and Fichier des evenements demographiques.3505 women with asthma, totalling 4593 pregnancies, between 1990 and 2000 (...) .Pregnancy induced hypertension and pre-eclampsia.302 cases of pregnancy induced hypertension and 165 cases of pre-eclampsia were identified. Use of inhaled corticosteroids from conception until date of outcome was not associated with an increased risk of pregnancy induced hypertension (adjusted odds ratio 1.02, 95% confidence interval 0.77 to 1.34) or pre-eclampsia (1.06, 0.74 to 1.53). No significant dose-response relation was observed between inhaled corticosteroids and pregnancy induced hypertension

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2005 BMJ

773. Corticosteroids for acute traumatic brain injury. (PubMed)

Corticosteroids for acute traumatic brain injury. Traumatic brain injury is a leading cause of death and disability. Corticosteroids have been widely used in treating people with traumatic brain injury.To quantify the effectiveness and safety of corticosteroids in the treatment of acute traumatic brain injury.Electronic sources: MEDLINE, EMBASE, Cochrane Library and specialised database searches. Additional hand searching and contact with trialists. Date of the most recent search October 2004 (...) .All randomised controlled trials of corticosteroid use in acute traumatic brain injury with adequate or unclear allocation concealment.Quality of allocation concealment was scored. Data on numbers of participants randomised, numbers lost to follow up, length of follow up, case fatality rates, disablement, infections and gastrointestinal bleeds were extracted independently and checked.We identified 20 trials with 12303 randomised participants. The effect of corticosteroids on the risk of death

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2005 Cochrane

774. Hay fever and a single intramuscular injection of corticosteroid: a systematic review

Hay fever and a single intramuscular injection of corticosteroid: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 DARE.

775. Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence

Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence Effects of inhaled corticosteroids on mortality and hospitalisation in elderly asthma and chronic obstructive pulmonary disease patients: appraising the evidence Schmier J K (...) , Halpern M T, Jones M L CRD summary This review examined the mortality and hospitalisation rates associated with the use of inhaled corticosteroids (ICS) in elderly patients with chronic obstructive pulmonary disease. The authors concluded that lower rates of hospitalisation and mortality were found to be associated with ICS use. However, concerns about potential biases in the review data mean that the findings are unlikely to be robust. Authors' objectives To review mortality and hospitalisation rates

2005 DARE.

776. Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma

Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma Mayers I, Damant R Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation Mayers I, Damant R. Role of combination inhaled corticosteroids and long acting beta agonists in the treatment of adult asthma. Ottawa: Canadian Coordinating Office for Health Technology Assessment (CCOHTA) 2005: 4 Authors' objectives The aim of this report is review the available information on the use of inhaled corticosteroids, combined in an inhaler with a long acting beta agonist, for treatment of persistent asthma (fixed dose combinations

2005 Health Technology Assessment (HTA) Database.

777. Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society

Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society Practice parameter: corticosteroid treatment of Duchenne dystrophy. Report (...) of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society Moxley R T, Ashwal S, Pandya S, Connolly A, Florence J, Mathews K, Baumbach L, McDonald C, Sussman M, Wade C CRD summary This review assessed the effects of corticosteroids in boys with Duchenne dystrophy. It concluded that prednisone can improve muscle strength and function and pulmonary function, and that deflazacort also provides similar benefits. This conclusion

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2005 DARE.

778. Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance organization

Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance organization Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance organization Economic evaluation of treating chronic obstructive pulmonary disease with inhaled corticosteroids and long-acting beta 2-agonists in a health maintenance (...) (COPD). The options were: long-acting beta2-antagonists (LABA) alone (e.g. salmeterol); inhaled corticosteroids (ICS; e.g. fluticasone propionate); a combination of ICS and LABA (ICS+LABA); and a "comparison" treatment that excluded the administration of ICS and LABA but included other COPD drugs, namely short-acting beta-antagonists, xanthine, anticholinergic or combined bronchodilators. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study

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2005 NHS Economic Evaluation Database.

779. Inhaled corticosteroids were safely stepped down in chronic, stable asthma

Inhaled corticosteroids were safely stepped down in chronic, stable asthma Inhaled corticosteroids were safely stepped down in chronic, stable asthma | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Inhaled corticosteroids were safely stepped down in chronic, stable asthma Article Text Therapeutics Inhaled corticosteroids were safely stepped down in chronic, stable asthma Free Jay I Peters , MD Statistics from Altmetric.com Hawkins G, McMahon

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2005 Evidence-Based Medicine

780. Effect of initial corticosteroid therapy on coronary artery aneurysm formation in Kawasaki disease: a meta-analysis of 862 children

Effect of initial corticosteroid therapy on coronary artery aneurysm formation in Kawasaki disease: a meta-analysis of 862 children Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 DARE.