Latest & greatest articles for corticosteroids

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Top results for corticosteroids

801. Cyclosporin as an oral corticosteroid sparing agent in stable asthma. (Abstract)

Cyclosporin as an oral corticosteroid sparing agent in stable asthma. Patients with chronic severe asthma are often dependent on the long term prescription of oral corticosteroids. The use of steroids is associated with serious side effects. Physicians treating such patients continue to search for alternative therapies that reduce the need for chronic dosing with oral steroids. Cyclosporin is an immunosuppressive agent and has benefits in the treatment of a number of inflammatory disorders (...) could be performed for measures of lung function although one study showed small, but significant improvements in lung spirometry.The changes with cyclosporin are small and of questionable clinical significance. Given the side effects of cyclosporin, the evidence available does not recommend routine use of this drug in the treatment of oral corticosteroid dependent asthma.

2001 Cochrane

802. Corticosteroids for induction of labour. (Abstract)

Corticosteroids for induction of labour. The role of corticosteroids in the process of labour is not well understood. Animal studies have shown the importance of cortisol secretion by the fetal adrenal gland in initiating labour in sheep. Infusion of glucocorticosteroids into the fetus has also shown to induce premature labour in sheep. Some assumptions have been proposed regarding the mode of action of corticosteroids, including both a paracrine and autocrine action, following (...) the identification of glucocorticoid receptors on human amnion. Given these studies it has been postulated that corticosteroids given intraamniotically will promote the induction of labour. This is one of a series of reviews of methods of cervical ripening and labour induction using standardised methodology.To determine the effects of corticosteroids for third trimester cervical ripening or induction of labour in comparison with other methods of cervical priming or induction of labour.The Cochrane Pregnancy

2001 Cochrane

803. Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. Full Text available with Trip Pro

Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy. Chronic inflammatory demyelinating polyradiculoneuropathy is an autoimmune peripheral neuropathy and would be expected to benefit from corticosteroids. Non-randomised studies suggest that corticosteroids are often beneficial.To evaluate the efficacy of corticosteroids for treating chronic inflammatory demyelinating polyradiculoneuropathy.Search of the Cochrane Neuromuscular Disease Group register for randomised (...) trials of corticosteroids treatment for chronic inflammatory demyelinating polyradiculoneuropathy and enquiry from subject experts.Types of studies: All randomised or quasi-randomised trials Types of participants: All patients with chronic inflammatory demyelinating polyradiculoneuropathy who were diagnosed by an internationally accepted definition. Types of interventions: Treatment with any form of corticosteroid or adrenocorticotropic hormone. Types of outcome measures:Change in disability 12 weeks

2001 Cochrane

804. Pharmacoeconomic impact of inhaled corticosteroids

Pharmacoeconomic impact of inhaled corticosteroids Pharmacoeconomic impact of inhaled corticosteroids Pharmacoeconomic impact of inhaled corticosteroids Stempel D A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use (...) of three inhaled corticosteroids (ICSs) for the treatment of persistent asthma. The ICSs were fluticasone, triamcinolone and zafirlukast. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population comprised patients suffering from persistent asthma, as defined by the International Classification of Diseases, 9th Revision (ICD-9) code (493.XX). Setting The setting of the study appears to have been the community. The economic study was carried

2000 NHS Economic Evaluation Database.

805. Should postmenopausal women with rheumatoid arthritis who are starting corticosteroid treatment be screened for osteoporosis? A cost-effectiveness analysis

Should postmenopausal women with rheumatoid arthritis who are starting corticosteroid treatment be screened for osteoporosis? A cost-effectiveness analysis Should postmenopausal women with rheumatoid arthritis who are starting corticosteroid treatment be screened for osteoporosis? A cost-effectiveness analysis Should postmenopausal women with rheumatoid arthritis who are starting corticosteroid treatment be screened for osteoporosis? A cost-effectiveness analysis Solomon D H, Kuntz K M Record (...) Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology This paper compared three strategies, namely waiting, screening and treating, for the prevention of corticosteroid-induced osteoporosis in postmenopausal women with rheumatoid arthritis (RA

2000 NHS Economic Evaluation Database.

806. The economic impact of intermittent high-dose intravenous versus oral corticosteroid treatment of juvenile dermatomyositis

The economic impact of intermittent high-dose intravenous versus oral corticosteroid treatment of juvenile dermatomyositis The economic impact of intermittent high-dose intravenous versus oral corticosteroid treatment of juvenile dermatomyositis The economic impact of intermittent high-dose intravenous versus oral corticosteroid treatment of juvenile dermatomyositis Klein-Gitelman M S, Waters T, Pachman L M Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology High-dose, intermittent intravenous corticosteroids (IVCS) in conjunction with low-dose daily oral corticosteroids (OCS) were compared with high-dose daily OCS alone in the treatment of juvenile dermatomyositis (JDM). The high-dose IVCS was 30 mg/kg per day (maximum

2000 NHS Economic Evaluation Database.

807. Practice parameter: the role of corticosteroids in the management of acute monosymptomatic optic neuritis. Report of the Quality Standards Subcommittee of the American Academy of Neurology

Practice parameter: the role of corticosteroids in the management of acute monosymptomatic optic neuritis. Report of the Quality Standards Subcommittee of the American Academy of Neurology Practice parameter: the role of corticosteroids in the management of acute monosymptomatic optic neuritis. Report of the Quality Standards Subcommittee of the American Academy of Neurology Practice parameter: the role of corticosteroids in the management of acute monosymptomatic optic neuritis. Report (...) of the Quality Standards Subcommittee of the American Academy of Neurology Kaufman D I, Trobe J D, Eggenberger E R, Whitaker J N Authors' objectives To evaluate the role of corticosteroids in the management of acute monosymptomatic optic neuritis (ON). Searching MEDLINE and HealthSTAR were searched from 1966 to July 1, 1999 for ON cross-referenced with treatment and therapy. Citations earlier than 1966 were searched by cross-referencing techniques and by handsearching Index Medicus. Only literature published

2000 DARE.

808. Postnatal corticosteroids in preterm infants: systematic review of effects on mortality and motor function

Postnatal corticosteroids in preterm infants: systematic review of effects on mortality and motor function Postnatal corticosteroids in preterm infants: systematic review of effects on mortality and motor function Postnatal corticosteroids in preterm infants: systematic review of effects on mortality and motor function Doyle L W, Davis P G Authors' objectives To review the evidence on the effects of postnatal corticosteroids in preterm infants on long-term mortality and motor dysfunction (...) (RCTs) or quasi-randomised trials were eligible. Duration of follow-up ranged from 28 days to 3 years of age. Specific interventions included in the review Parenteral or oral corticosteroids were eligible. Studies with only inhaled steroids were excluded. Dose of dexamethasone or equivalent dexamethasone dose ranged from 0.4 mg/kg to 8 mg/kg. Co-interventions included antenatal corticosteroid therapy and surfactant. The rate of antenatal corticosteroid therapy was low (< 50%) in most studies (range

2000 DARE.

809. Enteral nutrition and corticosteroids in the treatment of acute Crohn's disease in children

Enteral nutrition and corticosteroids in the treatment of acute Crohn's disease in children Enteral nutrition and corticosteroids in the treatment of acute Crohn's disease in children Enteral nutrition and corticosteroids in the treatment of acute Crohn's disease in children Heuschkel R B, Menache C C, Megerian J T, Baird A E Authors' objectives To compare the effectiveness of enteral nutrition and corticosteroids in the treatment of acute Crohn's Disease in children. Searching MEDLINE (from (...) more than once, and preliminary reports later published in full, were excluded. Specific interventions included in the review In terms of selection criteria, studies comparing enteral nutrition with corticosteroids in the treatment of Crohn's disease were included. In the included studies, the steroid doses used ranged between 0.2 and 2.4 mg/kg per day. In relation to the daily calorie intake, the following were used in the included studies: 75 kcal/kg; 50 to 80 kcal/kg; 100 to 140

2000 DARE.

810. Eficacia de los glucocorticoides en las reagudizaciones de la enfermedad pulmonar obstructiva cronica: metaanalisis de los estudios publicados [The efficacy of corticosteroids in exacerbations of chronic obstructive pulmonary disease: meta-analysis of pub

Eficacia de los glucocorticoides en las reagudizaciones de la enfermedad pulmonar obstructiva cronica: metaanalisis de los estudios publicados [The efficacy of corticosteroids in exacerbations of chronic obstructive pulmonary disease: meta-analysis of pub Eficacia de los glucocorticoides en las reagudizaciones de la enfermedad pulmonar obstructiva cronica: metaanalisis de los estudios publicados [The efficacy of corticosteroids in exacerbations of chronic obstructive pulmonary disease: meta (...) -analysis of published studies] Eficacia de los glucocorticoides en las reagudizaciones de la enfermedad pulmonar obstructiva cronica: metaanalisis de los estudios publicados [The efficacy of corticosteroids in exacerbations of chronic obstructive pulmonary disease: meta-analysis of published studies] Riancho J A, Portero I, Cubian I Authors' objectives To evaluate the efficacy of corticosteroids for exacerbations of chronic obstructive pulmonary disease (COPD). Searching MEDLINE (from 1966 to 1999

2000 DARE.

811. Systemic corticosteroids in infant bronchiolitis: a meta-analysis

Systemic corticosteroids in infant bronchiolitis: a meta-analysis Systemic corticosteroids in infant bronchiolitis: a meta-analysis Systemic corticosteroids in infant bronchiolitis: a meta-analysis Garrison M M, Christakis D A, Harvey E, Cummings P, Davis R L Authors' objectives To determine whether corticosteroids are efficacious in treating bronchiolitis in hospitalised infants. Searching The following sources were searched: MEDLINE from 1966 to January 1999, the Cochrane Controlled Trials (...) Register (as of January 1999), and EMBASE from January 1990 to January 1999. The search terms included 'bronchiolitis', 'respiratory syncytial viruses', 'adrenal cortex hormones', 'corticosteroid', 'glucocorticoid', 'antiinflammatory agents' and 'steroidal'. The bibliographies of review articles and all selected articles were examined. No language restrictions were reported. Study selection Study designs of evaluations included in the review Randomised placebo-controlled studies. The studies had

2000 DARE.

812. Corticosteroid treatment for idiopathic facial nerve paralysis: a meta-analysis

Corticosteroid treatment for idiopathic facial nerve paralysis: a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2000 DARE.

813. Inhaled corticosteroids for asthma

Inhaled corticosteroids for asthma Inhaled corticosteroids for asthma Inhaled corticosteroids for asthma Weber J Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Weber J. Inhaled corticosteroids for asthma. University HealthSystem Consortium (UHC). Drug Monograph. 2000 Authors' objectives The UHC Drug Monographs are a continuing series of authoritative, concise

2000 Health Technology Assessment (HTA) Database.

814. What is the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD?

What is the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD? What is the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD? What is the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD? Hender K Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation Hender K. What is the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD? Centre for Clinical Effectiveness (CCE). Evidence Centre Evidence Report. 2000 Authors' objectives This aim of this report was to assess the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD. Authors' conclusions - One systematic review was identified that met

2000 Health Technology Assessment (HTA) Database.

815. Antenatal Corticosteroids Revisited: Repeat Courses

Antenatal Corticosteroids Revisited: Repeat Courses NIH Consensus Statement Volume 17, Number 2 August 17–18, 2000 Antenatal Corticosteroids Revisited: Repeat Courses NATIONAL INSTITUTES OF HEALTH Office of the Director About the NIH Consensus Development Program NIH Consensus Development Conferences are convened to evaluate available scientific information and resolve safety and efficacy issues related to a biomedical technology. The resultant NIH Consensus Statements are intended to advance (...) of the second day and morning of the third. This statement is an independent report of the consensus panel and is not a policy statement of the NIH or the Federal Government. Reference Information For making bibliographic reference to this consensus statement, it is recommended that the following format be used, with or without source abbreviations, but without authorship attribution: Antenatal Corticosteroids Revisited: Repeat Courses. NIH Consensus Statement 2000 August 17–18; 17(2): 1–18. Publications

2000 NIH Consensus Statements

816. Systemic Corticosteroids in Infant Bronchiolitis: A Meta-analysis

Systemic Corticosteroids in Infant Bronchiolitis: A Meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2000 PedsCCM Evidence-Based Journal Club

817. Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer. Full Text available with Trip Pro

Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer. Gastrointestinal and ovarian cancers are common cancers. The incidence of associated malignant bowel obstruction in patients with advanced cancers of these types is not known, and the best management of these patients is controversial. Inappropriate management may result in uncontrolled (faeculant) vomiting, pain and distress. Management of the symptoms can include (...) palliative surgery, nasogastric tube suction together with intravenous fluids, or pharmacological means, such as corticosteroids. There is uncertainty regarding both the efficacy and possible harmful effects of corticosteroids, and also the most effective type, dose/dosing regime, route and period of administration.To locate, appraise and summarise evidence from scientific studies on intestinal obstruction due to advanced gynaecological and gastrointestinal cancer, in order to assess the efficacy

2000 Cochrane

818. Corticosteroids for treating Guillain-Barré syndrome. (Abstract)

Corticosteroids for treating Guillain-Barré syndrome. The cause of Guillain-Barré syndrome (GBS) is inflammation of the peripheral nerves which corticosteroids would be expected to benefit.To examine the efficacy of corticosteroids in hastening recovery and reducing the long term morbidity from Guillain-Barré syndrome (GBS).Search of the Cochrane Neuromuscular Disease Group register for randomised trials and enquiry from authors of trials and other experts in the field.Types of studies: quasi (...) -randomised or randomised controlled trialspatients with GBS of all ages and all degrees of severity Types of interventions: any form of corticosteroid or adrenocorticotrophic hormone Types of outcome measures: Primary: improvement in disability grade on a commonly used seven point scale four weeks after randomisation Secondary: time from randomisation until recovery of unaided walking, time from randomisation until discontinuation of ventilation (for those ventilated), mortality, proportion of patients

2000 Cochrane

819. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. (Abstract)

Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Post-extubation stridor may prolong length of stay in the intensive care unit, particularly if airway obstruction is severe and re-intubation proves necessary. Corticosteroids, however, may be associated with adverse effects ranging from hypertension to hyperglycemia, and a more systematic assessment of the efficacy of this therapy is indicated prior to widespread adoption (...) of this practiceTo determine whether corticosteroids are effective in preventing or treating post-extubation stridor in critically ill infants, children, or adults.Controlled trials were identified through MEDLINE, EMBASE and CINAHL. Bibliographies of all identified trials were examined, and authors of included trials were contacted to confirm the methodology and identify other potentially relevant trials.Any randomized controlled trial that compared administration of corticosteroids by any route with placebo

2000 Cochrane

820. Corticosteroids for pulmonary sarcoidosis. (Abstract)

Corticosteroids for pulmonary sarcoidosis. Pulmonary sarcoidosis is a common condition with an unpredictable course. Oral or inhaled steroids are widely used in its treatment, but there is no consensus about when and in whom therapy should be initiated, what dose should be given and for how long. Corticosteroids given for several months have deleterious side-effects so it is important to know whether they have any maintained benefit in pulmonary sarcoidosis.To determine the randomised (...) controlled trial (RCT) evidence for the benefit of corticosteroids (oral or inhaled) in the treatment of pulmonary sarcoidosis.The Cochrane Airways Group interstitial lung disease RCT register was searched using the terms: sarcoidosis and (steroid* OR corticosteroid* OR prednisolone OR prednisone OR beclomethasone OR budesonide OR fluticasone). Bibliographies of retrieved RCTs and reviews were searched for additional RCTs. Pharmaceutical companies and authors of identified RCTs were contacted for other

2000 Cochrane