Latest & greatest articles for corticosteroids

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on corticosteroids or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on corticosteroids and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for corticosteroids

81. Comparison of Ultrasound-Guided Local Ozone (O2-O3) Injection vs Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial

Comparison of Ultrasound-Guided Local Ozone (O2-O3) Injection vs Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial Plantar fasciitis (PF) is one of the most common causes of heel pain. The affected area is often close to the attachment of plantar fascia to calcaneus bone. The purpose of this study was to compare the effects of ozone (O2-O3) injection to corticosteroid injection under ultrasound guidance for the treatment of chronic PF.Randomized (...) thickness at insertion and 1 cm distal to its insertion into the calcaneus via ultrasound imaging.Intragroup changes showed significant improvement in pain, functional parameters, and sonographic findings in both groups (P < 0.05). Pain reduction (both daily and morning) and daily activity improvement were better in the corticosteroid group two weeks after injection; however, at 12 weeks, the ozone (O2-O3) group had significantly more improvement (P = 0.003, P = 0.001, and P = 0.017, respectively).Both

2018 EvidenceUpdates

82. Efficacy and safety of pulmonary application of corticosteroids in preterm infants with respiratory distress syndrome: a systematic review and meta-analysis (Full text)

Efficacy and safety of pulmonary application of corticosteroids in preterm infants with respiratory distress syndrome: a systematic review and meta-analysis Systemic corticosteroids as the frontline treatment of respiratory distress syndrome (RDS) in preterm infants are associated with adverse effects on growth and neurodevelopmental outcome, but the pulmonary administration of steroids may help prevent the development of bronchopulmonary dysplasia (BPD) without these side effects.To evaluate (...) the efficacy and safety of pulmonary application of corticosteroids in preterm infants with RDS.MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, the WHO's International Clinical Trials Registry and grey literature were searched with no restriction on date and language of publication from inception to May 2016. Using a random-effect model, we pooled data from randomised controlled trials (RCTs) comparing inhaled or endotracheal corticosteroids with the standard of care

2018 EvidenceUpdates PubMed

83. Usefulness of an Online Risk Estimator for Bronchopulmonary Dysplasia in Predicting Corticosteroid Treatment in Infants Born Preterm

Usefulness of an Online Risk Estimator for Bronchopulmonary Dysplasia in Predicting Corticosteroid Treatment in Infants Born Preterm To assess the usefulness of a bronchopulmonary dysplasia (BPD) outcome estimator developed by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in identifying high-risk preterm infants treated with steroids.This was a single-center retrospective study of infants born ≤30 weeks of gestational age. The NICHD BPD outcome

2018 EvidenceUpdates

84. Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part II) (Full text)

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part II) Guidelines for the Diagnosis and Management of Critical Illn... : Critical Care Medicine You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Login No user account? Lippincott Journals Subscribers , use your username or email along with your password to log in. Remember me (...) . Djillali Annane are co-chairs and co-first authors who have equally contributed to this work. A full list of the Corticosteroid Guideline Task Force of SCCM and ESICM investigators is presented in the supplementary material ( Supplemental Digital Content 3 , ). Dr. Pastores participates in the American College of Physicians: Speaker at ACP Critical Care Update Precourse, the American College of Chest Physicians (CHEST) (faculty speaker at Annual Congress), the American Thoracic Society (ATS): Moderator

2018 Society of Critical Care Medicine PubMed

85. Inhaled corticosteroids for bronchiectasis. (PubMed)

Inhaled corticosteroids for bronchiectasis. Bronchiectasis is being increasingly diagnosed and recognised as an important contributor to chronic lung disease in both adults and children in high- and low-income countries. It is characterised by irreversible dilatation of airways and is generally associated with airway inflammation and chronic bacterial infection. Medical management largely aims to reduce morbidity by controlling the symptoms, reduce exacerbation frequency, improve quality (...) of life and prevent the progression of bronchiectasis. This is an update of a review first published in 2000.To evaluate the efficacy and safety of inhaled corticosteroids (ICS) in children and adults with stable state bronchiectasis, specifically to assess whether the use of ICS: (1) reduces the severity and frequency of acute respiratory exacerbations; or (2) affects long-term pulmonary function decline.We searched the Cochrane Register of Controlled Trials (CENTRAL), the Cochrane Airways Group

2018 Cochrane

86. Education plus exercise versus corticosteroid injection use versus a wait and see approach on global outcome and pain from gluteal tendinopathy: prospective, single blinded, randomised clinical trial. (Full text)

Education plus exercise versus corticosteroid injection use versus a wait and see approach on global outcome and pain from gluteal tendinopathy: prospective, single blinded, randomised clinical trial. To compare the effects of a programme of load management education plus exercise, corticosteroid injection use, and no treatment on pain and global improvement in individuals with gluteal tendinopathy.Prospective, three arm, single blinded, randomised clinical trial.Brisbane and Melbourne (...) , Australia.Individuals aged 35-70 years, with lateral hip pain for more than three months, at least 4/10 on the pain numerical rating scale, and gluteal tendinopathy confirmed by clinical diagnosis and magnetic resonance imaging; and with no corticosteroid injection use in previous 12 months, current physiotherapy, total hip replacement, or neurological conditions.A physiotherapy led education and exercise programme of 14 sessions over eight weeks (EDX; n=69), one corticosteroid injection (CSI; n=66), and a wait

2018 BMJ PubMed

87. A Randomized, Multicenter, Double-Blind, Parallel Pilot Study Assessing the Effect of Mechanical Adhesiolysis vs Adhesiolysis with Corticosteroid and Hyaluronidase Administration into the Epidural Space During Epiduroscopy (Full text)

A Randomized, Multicenter, Double-Blind, Parallel Pilot Study Assessing the Effect of Mechanical Adhesiolysis vs Adhesiolysis with Corticosteroid and Hyaluronidase Administration into the Epidural Space During Epiduroscopy Epiduroscopy is a proven method of diagnosis and treatment for chronic radicular pain after spinal surgery, which is known as failed back surgery syndrome (FBSS). The aim of the study was to compare the efficacy of drugs (the enzyme hyaluronidase and corticosteroid DEPO (...) -Medrol) administrated into the epidural space during epiduroscopy, performed within the ventral and ventro-lateral epidural space with a focus on releasing foraminal adhesions. Forty-eight patients with diagnosed FBBS were randomized into two groups before epiduroscopy. Group A received the standard treatment-mechanical lysis of fibrotic tissue in the epidural space. Group B received hyaluronidase and corticosteroid methylprednisolone acetate during the procedure. Subjects were followed for six

2018 EvidenceUpdates PubMed

88. Corticosteroids for the prevention of bronchopulmonary dysplasia in preterm infants: a network meta-analysis (Full text)

Corticosteroids for the prevention of bronchopulmonary dysplasia in preterm infants: a network meta-analysis To determine the comparative efficacy and safety of corticosteroids in the prevention of bronchopulmonary dysplasia (BPD) in preterm infants.We systematically searched PubMed, EMBASE and the Cochrane Library. Two reviewers independently selected randomised controlled trials (RCTs) of postnatal corticosteroids in preterm infants. A Bayesian network meta-analysis and subgroup analyses were (...) ). There were no statistically significant differences in the risk of cerebral palsy (CP) between different corticosteroids. However, high-dose and long-term dexamethasone ranked lower than placebo and other regimens in terms of CP. Subgroup analyses indicated budesonide was associated with a decreased risk of BPD in extremely preterm and extremely low birthweight infants (OR 0.60, 95% CrI 0.36 to 0.93).Dexamethasone can reduce the risk of BPD in preterm infants. Of the different dexamethasone regimens

2018 EvidenceUpdates PubMed

89. Ultrasound-Guided Versus Landmark-Guided Local Corticosteroid Injection for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Ultrasound-Guided Versus Landmark-Guided Local Corticosteroid Injection for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials To review the literature and assess the comparative effectiveness of ultrasound-guided versus landmark-guided local corticosteroid injections in patients with carpal tunnel syndrome (CTS).Cochrane Central Register of Controlled Trials, MEDLINE (PubMed), Embase (Ovid), and Web of Science (from inception to February 1, 2017

2018 EvidenceUpdates

90. Can we reliably predict response to corticosteroid treatment in severe alcoholic hepatitis? (Full text)

Can we reliably predict response to corticosteroid treatment in severe alcoholic hepatitis? 29881814 2018 11 14 2471-254X 2 6 2018 Jun Hepatology communications Hepatol Commun Can we reliably predict response to corticosteroid treatment in severe alcoholic hepatitis? 625-627 10.1002/hep4.1191 Chokshi Shilpa S Chief Scientific Officer Institute of Hepatology Foundation for Liver Research London United Kingdom. eng Editorial 2018 04 27 United States Hepatol Commun 101695860 2471-254X 2018 03 29

2018 Hepatology communications PubMed

91. Moisturisers improve eczema symptoms and lessen the need for corticosteroids

Moisturisers improve eczema symptoms and lessen the need for corticosteroids Moisturisers improve eczema symptoms and lessen the need for corticosteroids Discover Portal Discover Portal Moisturisers improve eczema symptoms and lessen the need for corticosteroids Published on 27 June 2017 doi: Moisturisers help reduce eczema symptoms compared to no treatment, but to a minor extent. They do lengthen the time between each flare, and reduce the number of flares. Importantly they reduce the amount (...) of corticosteroid creams required. Moisturisers seem well tolerated, though there is little data on patient satisfaction. This Cochrane review of 77 trials does not provide information on which moisturiser might be preferred for different parts of the body or different disease severity. Nevertheless, since moisturisers reduce flares and form part of combined treatment with other active treatments, it makes sense to encourage their continued use. Given the lack of a one size fits all approach, people should have

2018 NIHR Dissemination Centre

92. A dose of corticosteroids benefit most women anticipating a preterm delivery

A dose of corticosteroids benefit most women anticipating a preterm delivery A dose of corticosteroids benefits most women anticipating a preterm delivery Discover Portal Discover Portal A dose of corticosteroids benefits most women anticipating a preterm delivery Published on 16 May 2017 doi: Giving corticosteroids to most women who are anticipating labour before completing 37 weeks of pregnancy helps reduce immediate health problems in the baby compared with placebo or no intervention. Deaths (...) around the time of birth were reduced by 28% and babies were a third (34%) less likely to develop respiratory distress syndrome. A corticosteroid dose is already used for women who go into labour or if waters break before 37 weeks or where delivery is planned for other reasons. The drug accelerates the development of the baby’s lungs and reduces breathing difficulties at birth. This recommendation followed decades of research. This review supports current practice of using a dose of corticosteroids

2018 NIHR Dissemination Centre

93. Corticosteroids given early reduce risk of heart problems in children with Kawasaki disease

Corticosteroids given early reduce risk of heart problems in children with Kawasaki disease Corticosteroids given early reduce risk of heart problems in children with Kawasaki disease Discover Portal Discover Portal Corticosteroids given early reduce risk of heart problems in children with Kawasaki disease Published on 14 February 2017 doi: Early treatment with corticosteroids on top of standard therapy reduces the risk of serious heart problems in children under five with the rare vascular (...) corticosteroids early to standard treatment within five days of onset of symptoms reduced the risk of serious abnormalities in the heart arteries by more than two thirds. Corticosteroids were not effective when used as rescue treatment after standard treatment had failed. Increasing awareness of the presenting symptoms of children with Kawasaki disease should ensure children are referred early for treatment. Specialist clinicians may want to consider adding corticosteroids to standard treatment

2018 NIHR Dissemination Centre

94. Antenatal corticosteroids reduce breathing problems in late preterm babies

Antenatal corticosteroids reduce breathing problems in late preterm babies Antenatal corticosteroids reduce breathing problems in late preterm babies Discover Portal Discover Portal Antenatal corticosteroids reduce breathing problems in late preterm babies Published on 21 February 2017 doi: Giving corticosteroids to women at risk of preterm birth at 34 weeks of pregnancy or later reduced the risk of severe breathing problems in the baby after birth from 1.9% to 1.1%. Steroids also reduced (...) monitoring. The risks and benefits need to be considered before further recommendations can be made extending the use of antenatal corticosteroids to this late preterm age. This includes exploring the long-term effects and consequences for specific groups of women such as those with diabetes or pregnant with more than one baby. Share your views on the research. Why was this study needed? In the UK, about one baby in every 13 is born prematurely, before 37 weeks of pregnancy. Preterm new-borns

2018 NIHR Dissemination Centre

95. Corticosteroid injections provide only short term relief for rotator cuff disorders

Corticosteroid injections provide only short term relief for rotator cuff disorders Corticosteroid injections provide only short term relief for rotator cuff disorders Discover Portal Discover Portal Corticosteroid injections provide only short term relief for rotator cuff disorders Published on 5 October 2016 doi: A corticosteroid steroid injection into the shoulder provides some short-term pain relief for adults with rotator cuff disorders. This review compared injection of corticosteroids (...) for recovery in these painful conditions. Share your views on the research. Why was this study needed? Shoulder disorders are common and affect about three in ten adults at any one time. Rotator cuff disorders are the most common cause of shoulder pain. The tendons in the shoulder can be vulnerable to injury or tear, getting trapped (impingement), or just gradual degeneration of the tendon as a normal part of aging. Giving a corticosteroid injection into the joint is one option to treat pain. Despite

2018 NIHR Dissemination Centre

96. Saline irrigation and corticosteroid spray are effective first choice treatments for chronic sinusitis

Saline irrigation and corticosteroid spray are effective first choice treatments for chronic sinusitis Saline irrigation and corticosteroid spray are effective first choice treatments for chronic sinusitis Discover Portal Discover Portal Saline irrigation and corticosteroid spray are effective first choice treatments for chronic sinusitis Published on 22 December 2015 doi: The authors of this systematic review found that high-volume saline irrigation and corticosteroid nasal sprays were (...) effective at reducing symptoms of sinusitis. They recommend a combination of these two therapies as the first line treatment of choice, in accordance with guidelines from the Royal College of Surgeons and ENT UK. In addition they found that, in those with nasal polyps, corticosteroids sprays reduced the polyp size, and during acute exacerbations a two to three week course of oral corticosteroids, doxycycline or a leukotriene antagonist was the most effective strategy. For those without polyps a three

2018 NIHR Dissemination Centre

97. New evidence available on corticosteroids added to antibiotics in severe pneumonia

New evidence available on corticosteroids added to antibiotics in severe pneumonia New evidence available on corticosteroids added to antibiotics in severe pneumonia Discover Portal Discover Portal New evidence available on corticosteroids added to antibiotics in severe pneumonia Published on 9 November 2015 doi: For adults admitted to hospital with severe pneumonia, this review found that adding corticosteroids to the usual antibiotic treatment may be beneficial. The evidence was less (...) supportive of using corticosteroids in people with less severe pneumonia. Results showed modest benefits in allowing patients to reach a clinically stable recovery and leave hospital an average of one day earlier. Reduced need for artificial breathing support was the main benefit for people with non-severe pneumonia. The review showed that using corticosteroids increased levels of blood sugar. This and other potential adverse events were not well investigated, as people at risk of them were excluded from

2018 NIHR Dissemination Centre

98. Corticosteroids could help reduce deaths due to blood poisoning

Corticosteroids could help reduce deaths due to blood poisoning Corticosteroids could help reduce deaths due to blood poisoning Discover Portal Discover Portal Corticosteroids could help reduce deaths due to blood poisoning Published on 23 March 2016 doi: Treatment with low dose corticosteroids given over three or more days reduces the death rate from blood poisoning by 13%, saving about 43 lives per 1000 treated at one month. Blood sugar and sodium levels rose slightly (...) but there was no increased risk of gastrointestinal bleeding or additional infection. Current international guidance from 2012 only recommends using corticosteroids as an add-on therapy for people with blood poisoning whose circulation has not been restored by adequate fluid replacement and vasopressors. This review lends some weight to the case for using corticosteroids more widely for sepsis, but is not definitive. This uncertainty is due to inconsistency in results, with some trials finding no difference in mortality

2018 NIHR Dissemination Centre

99. Corticosteroids improve recovery rates after Bell’s palsy

Corticosteroids improve recovery rates after Bell’s palsy Corticosteroids improve recovery rates after Bell’s palsy Discover Portal Discover Portal Corticosteroids improve recovery rates after Bell’s palsy Published on 29 November 2016 doi: Taking a corticosteroid within 72 hours of Bell’s palsy first appearing reduces the number of people with incomplete facial recovery after six months. Bell’s palsy is a sudden onset of weakness or paralysis of the muscles on one side of the face. Most people (...) recover completely within nine months, often with no treatment, but about three in 10 people are left with some weakness or unwanted facial movements. This Cochrane review found that ten people needed to be treated with corticosteroid, compared to placebo tablets, to avoid one incomplete recovery. It also showed that side effects were uncommon and mild. Corticosteroids are often already prescribed to treat Bell’s palsy in practice. This review confirms that they help. Any further trials should compare

2018 NIHR Dissemination Centre

100. Muscle loss following a single high-dose intramuscular injection of corticosteroids to treat disease flare in patients with rheumatoid arthritis (Full text)

Muscle loss following a single high-dose intramuscular injection of corticosteroids to treat disease flare in patients with rheumatoid arthritis Adverse changes in body composition, specifically decreased muscle mass (MM) and increased fat mass, characterize rheumatoid arthritis (RA). These changes, termed rheumatoid cachexia (RC), are important contributors to the disability and elevated co-morbidity risk of RA. Recently, we observed substantial muscle loss (~2 kg) in a patient with RA (...) following a single intramuscular (IM) corticosteroid (CS) injection to treat a disease flare. The aim of the current study is to determine whether this apparent iatrogenic effect of IM CS is typical, i.e., does this routine, recommended treatment contribute to RC?Body composition was assessed by dual-energy X-ray absorptiometry (DXA) in eight patients with established RA who received a 120 mg IM methylprednisolone injection to treat a disease flare. DXA scans estimated appendicular lean mass (ALM

2018 European journal of rheumatology PubMed