Latest & greatest articles for delirium

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Top results for delirium

121. Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial. (Full text)

Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial. Effective therapy has not been established for patients with agitated delirium receiving mechanical ventilation.To determine the effectiveness of dexmedetomidine when added to standard care in patients with agitated delirium receiving mechanical ventilation.The Dexmedetomidine to Lessen ICU Agitation (DahLIA) study was a double-blind, placebo-controlled (...) , parallel-group randomized clinical trial involving 74 adult patients in whom extubation was considered inappropriate because of the severity of agitation and delirium. The study was conducted at 15 intensive care units in Australia and New Zealand from May 2011 until December 2013. Patients with advanced dementia or traumatic brain injury were excluded.Bedside nursing staff administered dexmedetomidine (or placebo) initially at a rate of 0.5 µg/kg/h and then titrated to rates between 0 and 1.5 µg/kg/h

2016 JAMA PubMed

122. Interventions for preventing delirium in hospitalised non-ICU patients. (Full text)

Interventions for preventing delirium in hospitalised non-ICU patients. Delirium is a common mental disorder, which is distressing and has serious adverse outcomes in hospitalised patients. Prevention of delirium is desirable from the perspective of patients and carers, and healthcare providers. It is currently unclear, however, whether interventions for preventing delirium are effective.To assess the effectiveness of interventions for preventing delirium in hospitalised non-Intensive Care Unit (...) (ICU) patients.We searched ALOIS - the Cochrane Dementia and Cognitive Improvement Group's Specialized Register on 4 December 2015 for all randomised studies on preventing delirium. We also searched MEDLINE (Ovid SP), EMBASE (Ovid SP), PsycINFO (Ovid SP), Central (The Cochrane Library), CINAHL (EBSCOhost), LILACS (BIREME), Web of Science core collection (ISI Web of Science), ClinicalTrials.gov and the WHO meta register of trials, ICTRP.We included randomised controlled trials (RCTs) of single

2016 Cochrane PubMed

123. Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines

Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines (...) : Clinical Effectiveness and Guidelines Published on: January 14, 2016 Project Number: RC0744-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other sedative hypnotic agents? What are the evidence-based guidelines for the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

124. Systematic review and meta-analysis: Earplugs might reduce intensive care unit delirium but quality of evidence is low

Systematic review and meta-analysis: Earplugs might reduce intensive care unit delirium but quality of evidence is low Earplugs might reduce intensive care unit delirium but quality of evidence is low | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Earplugs might reduce intensive care unit delirium but quality of evidence is low Article Text Therapeutics/Prevention Systematic review and meta-analysis Earplugs might reduce intensive

2016 Evidence-Based Medicine (Requires free registration)

125. Routine use of antipsychotics to prevent or treat delirium is not recommended

Routine use of antipsychotics to prevent or treat delirium is not recommended Routine use of antipsychotics to prevent or treat delirium is not recommended | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Routine use of antipsychotics to prevent or treat delirium is not recommended Article Text Commentaries Pharmacological interventions Routine use of antipsychotics to prevent or treat delirium is not recommended Taro Kishi Statistics

2016 Evidence-Based Mental Health

126. Pediatric delirium and associated risk factors: a single-center prospective observational study

Pediatric delirium and associated risk factors: a single-center prospective observational study PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2015 PedsCCM Evidence-Based Journal Club

127. Effectiveness of haloperidol prophylaxis in critically ill patients with a high risk for delirium: a systematic review of quantitative evidence protocol. (PubMed)

Effectiveness of haloperidol prophylaxis in critically ill patients with a high risk for delirium: a systematic review of quantitative evidence protocol. 26455848 2016 05 25 2018 12 02 2202-4433 13 7 2015 Aug 14 JBI database of systematic reviews and implementation reports JBI Database System Rev Implement Rep Effectiveness of haloperidol prophylaxis in critically ill patients with a high risk for delirium: a systematic review of quantitative evidence protocol. 83-92 10.11124/jbisrir-2015-2301 (...) . Rodrigues Manuel M Health Sciences Research Unit: Nursing, Nursing School of Coimbra, The Portugal Centre for Evidence Based Practice: a Collaborating center of The Joanna Briggs Institute. eng Journal Article 2015 08 14 Australia JBI Database System Rev Implement Rep 101648258 2202-4433 0 Antipsychotic Agents J6292F8L3D Haloperidol IM Adolescent Adult Aged Antipsychotic Agents therapeutic use Critical Illness Delirium prevention & control Haloperidol therapeutic use Humans Intensive Care Units Middle

2015 JBI database of systematic reviews and implementation reports

128. The use of dexmedetomidine as an adjuvant to benzodiazepine-based therapy to decrease the severity of delirium in alcohol withdrawal in adult intensive care unit patients: a systematic review. (PubMed)

The use of dexmedetomidine as an adjuvant to benzodiazepine-based therapy to decrease the severity of delirium in alcohol withdrawal in adult intensive care unit patients: a systematic review. Chronic alcohol consumption is a prevalent issue. Healthcare professionals often discover their patient has an alcohol consumption issue when they are admitted to the hospital and no longer have access to alcohol. The global standard for treating alcohol withdrawal syndrome (AWS) symptoms (...) are benzodiazepines; however this therapy is often inadequate to control symptoms of delirium in adult intensive care unit (ICU) patients due to an imbalance of inhibitory and excitatory neurotransmitters.The objective of the systematic review is to examine the clinical effectiveness of dexmedetomidine as an adjuvant to benzodiazepine-based therapy versus benzodiazepine-based therapy alone in decreasing the severity of delirium associated with AWS in adult ICU patients.This review considered studies that included

2015 JBI database of systematic reviews and implementation reports

129. Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness

Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness | CADTH.ca Find the information you need Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness Published (...) on: September 10, 2015 Project Number: RA0806-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the clinical effectiveness of using constant observation monitors for geriatric patients with dementia or delirium? What is the cost-effectiveness of using constant observation monitors for geriatric patients with dementia or delirium? Key Message No relevant literature was identified regarding the clinical or cost-effectiveness of using constant

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

130. Delirium and cognitive decline after surgery: a randomised controlled trial of anaesthetic management to improve postoperative mental health outcome. (PubMed)

Delirium and cognitive decline after surgery: a randomised controlled trial of anaesthetic management to improve postoperative mental health outcome. 25647822 2015 09 28 2016 10 20 1024-2708 20 Suppl 7 2014 Dec Hong Kong medical journal = Xianggang yi xue za zhi Hong Kong Med J Delirium and cognitive decline after surgery: a randomised controlled trial of anaesthetic management to improve postoperative mental health outcome. 28-9 Chan M T V MT Department of Anaesthesia and Intensive Care (...) , The Chinese University of Hong Kong. Gin T T Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong. eng Comparative Study Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't China Hong Kong Med J 9512509 1024-2708 0 Anesthetics IM Aged Anesthetics administration & dosage Cognition Disorders epidemiology etiology prevention & control Colon surgery Consciousness Monitors Delirium epidemiology etiology prevention & control Humans Postoperative

2015 Hong Kong medical journal = Xianggang yi xue za zhi

131. The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients (Full text)

The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients Delirium is frequently missed in older emergency department (ED) patients. Brief (<2 minutes) delirium assessments have been validated for the ED, but some ED health care providers may consider them to be cumbersome. The Richmond Agitation Sedation Scale (RASS) is an observational scale that quantifies level of consciousness and takes less than 10 seconds to perform (...) . The authors sought to explore the diagnostic accuracy of the RASS for delirium in older ED patients.This was a preplanned analysis of a prospective observational study designed to validate brief delirium assessments for the ED. The study was conducted at an academic ED and enrolled patients who were 65 years or older. Patients who were non-English-speaking, deaf, blind, comatose or had end-stage dementia were excluded. A research assistant (RA) and a physician performed the RASS at the time of enrollment

2015 EvidenceUpdates PubMed

132. [Delirium after open cardiac surgery:systematic review of prevalence, risk factors and consequences]. (PubMed)

[Delirium after open cardiac surgery:systematic review of prevalence, risk factors and consequences]. Delirium is a sudden and usually transient disturbance in consciousness, attention, cognition, perception and emotions. The pathophysiology is unknown but possible causes include neurotransmitter disturbances and inflammation reaction. Delirium is common in patients after open cardiac surgeries and can lead to serious consequences. Research shows that delirium is an underdiagnosed (...) and undertreated problem. The purpose of this systematic review is to illuminate the prevalence, risk factors and outcome of postoperative delirium following open cardiac surgery. A systematic literature review from 2005-2013 was performed aiming to determine the prevalence, predisposing and precipitating factors and outcome after postoperative delirium following cardiac surgery. Web of Science, PubMed and Cinahl were searched. Findings of the systematic review shows that about one third of patients become

2015 Laeknabladid

133. Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery (Full text)

Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery Postoperative delirium is common in patients recovering from cardiac surgery. Tight glucose control has been shown to reduce mortality and morbidity. Therefore, the authors sought to determine the effect of tight intraoperative glucose control using a hyperinsulinemic-normoglycemic clamp approach on postoperative delirium in patients undergoing cardiac surgery.The authors enrolled (...) 198 adult patients having cardiac surgery in this randomized, double-blind, single-center trial. Patients were randomly assigned to either tight intraoperative glucose control with a hyperinsulinemic-normoglycemic clamp (target blood glucose, 80 to 110 mg/dl) or standard therapy (conventional insulin administration with blood glucose target, <150 mg/dl). Delirium was assessed using a comprehensive delirium battery. The authors considered patients to have experienced postoperative delirium when

2015 EvidenceUpdates PubMed

134. Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines

Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses (...) with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines DATE: 17 April 2015 RESEARCH QUESTIONS 1. What is the clinical effectiveness of the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other sedative hypnotic agents? 2. What are the evidence-based guidelines for the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other sedative hypnotic agents? KEY FINDINGS Three systematic reviews

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

135. Delirium

Delirium Scottish Palliative Care Guidelines - Delirium Scottish Palliative Care Guidelines search / / / Delirium Delirium Introduction In this guideline, delirium is defined as disturbed consciousness and inattention with cognitive impairment; acute onset and fluctuating course as a physiological consequence of disease or treatment. Delirium is often reversible. Other terms used to describe delirium include acute confusional state, agitation, and terminal restlessness, but the terms (...) and deafness are risk factors. Differential diagnosis: , dementia (increased risk of developing delirium). Investigations Check full blood count and biochemistry, including calcium Check for infection (urine infection in the elderly) Review all medication and stop any non-essential drugs Assess for sensory impairment Check for opioid toxicity (drowsiness, agitation, myoclonus, hypersensitivity to touch) reduce opioid dose by 1/3rd. Consider switching to another opioid if delirium persists Check

2015 Scottish Palliative Care Guidelines

136. The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia

The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time (...) . To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The 3D-CAM provides a brief, easy to use, sensitive and specific delirium

2015 Evidence-Based Mental Health

137. Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of externally derived risk scores (Full text)

Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of externally derived risk scores reliable delirium risk stratification will aid recognition, anticipation and prevention and will facilitate targeting of resources in clinical practice as well as identification of at-risk patients for research. Delirium risk scores have been derived for acute medicine, but none has been prospectively validated in external cohorts. We therefore aimed to determine (...) the reliability of externally derived risk scores in a consecutive cohort of older acute medicine patients.consecutive patients aged ≥65 over two 8-week periods (2010, 2012) were screened prospectively for delirium using the Confusion Assessment Method (CAM), and delirium was diagnosed using the DSM IV criteria. The reliability of existing delirium risk scores derived in acute medicine cohorts and simplified for use in routine clinical practice (USA, n = 2; Spain, n = 1; Indonesia, n = 1) was determined

2015 EvidenceUpdates PubMed

138. 3D-CAM: Derivation and Validation of a 3-Minute Diagnostic Interview for CAM-Defined Delirium: A Cross-sectional Diagnostic Test Study. (Full text)

3D-CAM: Derivation and Validation of a 3-Minute Diagnostic Interview for CAM-Defined Delirium: A Cross-sectional Diagnostic Test Study. Delirium is common, leads to other adverse outcomes, and is costly. However, it often remains unrecognized in most clinical settings. The Confusion Assessment Method (CAM) is the most widely used diagnostic algorithm, and operationalizing its features would be a substantial advance for clinical care.To derive the 3D-CAM, a new 3-minute diagnostic assessment (...) for CAM-defined delirium, and validate it against a clinical reference standard.Derivation and validation study.4 general medicine units in an academic medical center.201 inpatients aged 75 years or older.20 items that best operationalized the 4 CAM diagnostic features were identified to create the 3D-CAM. For prospective validation, 3D-CAM assessments were administered by trained research assistants. Clinicians independently did an extensive assessment, including patient and family interviews

2014 Annals of Internal Medicine PubMed

139. Cornell Assessment of Pediatric Delirium: A Valid, Rapid, Observational Tool for Screening Delirium in the PICU

Cornell Assessment of Pediatric Delirium: A Valid, Rapid, Observational Tool for Screening Delirium in the PICU PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

140. Tryptophan Supplementation and Postoperative Delirium-A Randomized Controlled Trial (Full text)

Tryptophan Supplementation and Postoperative Delirium-A Randomized Controlled Trial To determine whether the postoperative administration of tryptophan would be beneficial for elderly adults undergoing surgery who are at risk of developing postoperative delirium.Randomized, double-blind, placebo-controlled trial.Denver Veterans Affairs Medical Center.Individuals aged 60 and older undergoing major elective operations requiring a postoperative intensive care unit (ICU) admission (n = 325).L (...) -tryptophan, 1 g orally three times a day or placebo was started after surgery and continued for up to 3 days postoperatively.Delirium and its motor subtypes were measured using the Confusion Assessment Method-Intensive Care Unit (CAM-ICU) and the Richmond Agitation and Sedation Scale. The primary outcome for between-group comparison was the incidence of excitatory (mixed and hyperactive) postoperative delirium. The secondary outcomes for comparison were the incidence and duration of overall postoperative

2014 EvidenceUpdates PubMed