Latest & greatest articles for depression

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on depression or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on depression and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for depression

2321. Counselling in a general practice setting: controlled study of health visitor intervention in treatment of postnatal depression. (Full text)

Counselling in a general practice setting: controlled study of health visitor intervention in treatment of postnatal depression. To determine whether counselling by health visitors is helpful in managing postnatal depression.Controlled, random order trial.Health centres in Edinburgh and Livingston.Sixty women identified as depressed by screening at six weeks post partum and by psychiatric interview at about 13 weeks post partum. Five women did not wish to participate, and a further five did (...) not complete the trial. Age, social and obstetric factors, and diagnosis were similar in women who completed the trial and those who withdrew.Eight weekly counselling visits by health visitors who had been given a short training in counselling for postnatal depression.Reduction of depression. MEASUREMENTS and main results--Standardised psychiatric interviews and a 10 point self report scale were used to identify depression before and after intervention. The psychiatrist was not told to which group women

1989 BMJ PubMed

2322. Nortriptyline treatment of post-stroke depression: a double-blind study. (PubMed)

Nortriptyline treatment of post-stroke depression: a double-blind study. The efficacy of nortriptyline in the treatment of post-stroke depression was assessed by a double-blind study in thirty-four patients. Half of the patients had major depression. There was a significantly greater improvement in depression in patients treated with nortriptyline than in a similar group of placebo-treated patients. Depression was measured by the Hamilton depression scale, Zung depression scale, present state (...) examination, and an overall depression scale. Successfully treated patients had serum nortriptyline levels in the therapeutic range. Post-stroke depressions are common, severe, and longstanding, and the demonstrated efficacy of nortriptyline provides an important addition to the treatments available for stroke patients.

1984 Lancet

2323. Comparison of alprazolam, imipramine, and placebo in the treatment of depression. (PubMed)

Comparison of alprazolam, imipramine, and placebo in the treatment of depression. Alprazolam is the first of the triazolobenzodiazepines to be studied in a large population of depressed patients. In a six-week, double-blind multicenter comparison of alprazolam, imipramine hydrochloride, and placebo in the treatment of 723 patients with depression, the two active drugs were statistically more effective than placebo. Alprazolam was at least as effective as imipramine in relieving depressive

1983 JAMA

2324. Double-blind controlled trail of electroconvulsive therapy (E.C.T.) and simulated E.C.T. in depressive illness. (PubMed)

Double-blind controlled trail of electroconvulsive therapy (E.C.T.) and simulated E.C.T. in depressive illness. 40 patients prescribed electroconvulsive therapy (E.C.T.) for treatment of a depressive illness were randomly allocated to two groups. One group had the first two E.C.T. treatments replaced by simulated E.C.T. on a double-blind basis. The results show that E.C.T. is significantly superior to simulated E.C.T. in the treatment of depressive illness.

1978 Lancet

2325. Drug treatment in depression. Antidepressant or tranquilizer? (PubMed)

Drug treatment in depression. Antidepressant or tranquilizer? 5340332 1967 10 02 2016 10 17 0098-7484 201 9 1967 Aug 28 JAMA JAMA Drug treatment in depression. Antidepressant or tranquilizer? 675-81 Rickels K K Raab E E DeSilverio R R Etemad B B eng Clinical Trial Comparative Study Journal Article Randomized Controlled Trial United States JAMA 7501160 0098-7484 0 Antidepressive Agents 0 Placebos 9I7LNY769Q Meprobamate AIM IM Adult Antidepressive Agents therapeutic use Anxiety Disorders drug (...) therapy Clinical Trials as Topic Depression drug therapy Female Humans Male Meprobamate therapeutic use Placebos 1967 8 28 1967 8 28 0 1 1967 8 28 0 0 ppublish 5340332

1967 JAMA