Latest & greatest articles for elderly

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Top results for elderly

981. The effects of antihypertensive therapy on left ventricular mass in elderly patients. (PubMed)

The effects of antihypertensive therapy on left ventricular mass in elderly patients. Left ventricular mass sometimes decreases during treatment of hypertension, but this response is inconsistent and its effects on left ventricular function are unknown. In a six-month randomized trial, we studied the ability of verapamil and atenolol to reduce left ventricular mass in 42 elderly patients with hypertension and the effects of this reduction in mass on cardiac function. The mean blood pressure (...) ejection rate, were significantly higher than before treatment (2.42 +/- 0.2 vs. 3.31 +/- 0.4 [P less than 0.05] and 0.61 +/- 0.03 to 0.85 +/- 0.05 [P less than 0.05], respectively). Diastolic filling was unchanged in the group that had no reduction in left ventricular mass. Cardiac output and the ejection fraction at rest and during mild exercise were unchanged in both groups as compared with baseline values. We conclude that left ventricular mass can be reduced in elderly patients with hypertension

1990 NEJM

982. Locomotor disability in very elderly people: value of a programme for screening and provision of aids for daily living. (PubMed)

Locomotor disability in very elderly people: value of a programme for screening and provision of aids for daily living. To assess the prevalence of potentially reversible locomotor disabilities in elderly subjects and the cost effectiveness of providing aids for daily living.Population based randomised controlled trial of subjects aged greater than or equal to 85 living independently in an inner London borough.21 Electoral wards of the London Borough of Hackney.1255 Subjects aged greater than (...) intervention group v control group: raised toilet seat, 71 v 13 teapot tipper 100 v 33; tap turner 100 v 0; saucepan 88 v 0; shoe horn 50 v 13) and time taken to complete the tasks. A cost benefit analysis of this screening-intervention programme suggested a total cost of 32 pounds per individual benefit.Appreciable degrees of unrecognised locomotor disability are detected on screening of very elderly people living independently. Providing aids offers a feasible and cost effective means of improving

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1990 BMJ

983. Measuring blood pressure in the elderly: does atrial fibrillation increase observer variability? (PubMed)

Measuring blood pressure in the elderly: does atrial fibrillation increase observer variability? To compare the interobserver and intraobserver variability of blood pressure measurements in geriatric patients in atrial fibrillation and in sinus rhythm.Prospective assessment of blood pressure measurements carried out in random order in two groups of elderly patients by five doctors unaware of the aims of the study.Acute assessment wards for geriatric medicine, Cardiff Royal Infirmary.50 Elderly

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1990 BMJ

984. Relation between mortality and treated blood pressure in elderly patients with hypertension: report of the European Working Party on High Blood Pressure in the Elderly. (PubMed)

Relation between mortality and treated blood pressure in elderly patients with hypertension: report of the European Working Party on High Blood Pressure in the Elderly. To investigate the relation between mortality and treated systolic and diastolic blood pressures.Randomised double blind placebo controlled trial. Mortality in the two treatment groups was examined in thirds of treated systolic and diastolic blood pressures.339 And 352 patients allocated to placebo and active treatment

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1989 BMJ

985. Reduction in hospital readmission stay of elderly patients by a community based hospital discharge scheme: a randomised controlled trial. (PubMed)

Reduction in hospital readmission stay of elderly patients by a community based hospital discharge scheme: a randomised controlled trial. To compare a community support scheme using care attendants with standard aftercare for their effects on independence and morale of elderly patients discharged from hospital and on their use of health and social services.Randomised controlled study of cohort of patients over 75 discharged to their own homes.District general hospital and community.Total of 903

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1988 BMJ

986. Comparison of mastectomy with tamoxifen for treating elderly patients with operable breast cancer. (PubMed)

Comparison of mastectomy with tamoxifen for treating elderly patients with operable breast cancer. Comparison of tamoxifen and mastectomy in treatment of breast cancer in elderly patients.Randomised trial of treatment of operable breast cancer by wedge mastectomy or tamoxifen, with median follow up 24 and 25 months respectively (range 1-63).University hospital; most patients from primary catchment area.135 consecutive patients with breast cancer aged over 70 with operable tumours (less than 5 (...) and free of local recurrence at 24 months; in tamoxifen group only 47% remained alive and free of local progression. In mastectomy group locoregional recurrence occurred in 16 patients and metastatic disease in 13; in tamoxifen group locoregional progression occurred in 29 patients and metastatic disease in seven.As a high proportion of patients treated with tamoxifen eventually required surgery treatment of elderly patients with breast cancer should include mastectomy. Optimum treatment may include

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1988 BMJ

987. Prospective randomised trial of tamoxifen versus surgery in elderly patients with breast cancer. (PubMed)

Prospective randomised trial of tamoxifen versus surgery in elderly patients with breast cancer. 116 patients aged 70 or over who were judged to have surgically resectable cancer of the breast were prospectively randomised to tamoxifen 20 mg daily or surgical resection. At a median follow-up of three years, local relapse or progression was seen in 15 (25%) of 60 patients in the tamoxifen group and 21 (37.5%) of 56 in the surgical arm. Distant metastases occurred in 8 (13%) in the tamoxifen

1988 Lancet

988. Effectiveness of geriatric rehabilitative care after fractures of the proximal femur in elderly women: a randomised clinical trial. (PubMed)

Effectiveness of geriatric rehabilitative care after fractures of the proximal femur in elderly women: a randomised clinical trial. To compare postoperative collaborative care between orthopaedic surgeons and physicians in geriatric medicine with routine orthopaedic care in elderly women with proximal femoral fracture.Exclusion of patients dying before fit enough to enter trial, those with pathological fractures, those likely to be discharged within seven days of entering the trial, and those (...) remaining unfit for transfer to a peripheral hospital. Remainder allocated to two groups: treatment group and control group.District hospital acute admission ward and rehabilitation ward.144 sequentially admitted elderly women with proximal fracture of the femur; 36 excluded on above criteria and remainder entered into trial.Both treatment and control groups (n = 54 in each) received physiotherapy and other services. The treatment group also received thrice weekly supervision by a geriatrician.Physical

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1988 BMJ

989. Cost-effectiveness of primary tetanus vaccination among elderly Canadians

Cost-effectiveness of primary tetanus vaccination among elderly Canadians Cost-effectiveness of primary tetanus vaccination among elderly Canadians Cost-effectiveness of primary tetanus vaccination among elderly Canadians Hutchison B G, Stoddart G L Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment (...) among elderly Canadians. CMAJ: Canadian Medical Association Journal 1988; 139(12): 1143-1151 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Aged; Canada; Cost-Benefit Analysis; Female; Humans; Male; Postal Service; Tetanus /economics /prevention & Tetanus Toxoid; Vaccination /economics; control AccessionNumber 21995005282 Date bibliographic record published 06/08/1996 Date abstract record published 06/08/1996 NHS Economic Evaluation Database (NHS EED) Produced by the Centre

1988 NHS Economic Evaluation Database.

990. Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. (PubMed)

Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women. This prospective randomized study was undertaken to determine the efficacy of antimicrobial therapy compared with no therapy for bacteriuria in elderly ambulatory nonhospitalized women. Sixty-one women (mean age, 85.8 years) with bacteriuria were in the no therapy control group and 63 women (mean age, 85.8 years) with bacteriuria were in the therapy group; none had symptoms of urinary tract infection. One short (...) in elderly ambulatory nonhospitalized women, short-course antimicrobial therapy is effective at two-week follow-up and that antimicrobial therapy can eliminate bacteriuria in most of these women for at least a six-month period.

1987 JAMA

991. Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial. (PubMed)

Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial. A double-blind randomised placebo-controlled trial of antihypertensive treatment was conducted in patients over the age of 60. Entry criteria included both a sitting diastolic blood pressure on placebo treatment in the range 90-119 mm Hg and a systolic pressure in the range 160-239 mm Hg. 840 patients were randomised either to active treatment (hydrochlorothiazide + triamterene

1985 Lancet

992. Continuity of outpatient medical care in elderly men. A randomized trial. (PubMed)

Continuity of outpatient medical care in elderly men. A randomized trial. P6 an outpatient repeatedly sees the same practitioner, is his care influenced? This double-blind randomized trial examines the effects of outpatient health care provider continuity on the process and outcome of the medical care for 776 men aged 55 years and older. Participants were randomized to two different groups of provider care: provider discontinuity and provider continuity. The outcome of the continuity group

1984 JAMA

993. Screening for subclinical osteomalacia in the elderly: normal ranges or pragmatism? (PubMed)

Screening for subclinical osteomalacia in the elderly: normal ranges or pragmatism? Although osteomalacia is known to be common in some sections of the elderly population, the disease is often subclinical and there is uncertainty about the point at which treatment is necessary. Identification and treatment of osteomalacia are inseparably bound; the response of varying degrees of subclinical disease to treatment with vitamin D or alfacalcidol is described here. The response is assessed (...) in relation to a simply derived reference range based on standard biochemical measurements together with a Jamshidi needle biopsy of the iliac crest. Although this technique does not define a truly normal range it identifies a treatable abnormality which could form the basis of further study of the problem of subclinical osteomalacia in the elderly.

1983 Lancet

994. Bacteriuria in elderly institutionalized men. (PubMed)

Bacteriuria in elderly institutionalized men. Over a two-year period we obtained monthly urine samples from all noncatheterized male residents on two geriatric wards to determine the occurrence and optimal management of bacteriuria in this population. Among 88 men the prevalence of bacteriuria was 33 per cent, and the incidence was 45 infections per 100 patients per year. Outcomes after single-dose therapy for asymptomatic bacteriuria with 43 courses of trimethoprim/sulfamethoxazole and 23 (...) randomization were similar in the two groups. These data suggest that asymptomatic bacteriuria is common in elderly institutionalized men and that therapy is neither necessary nor effective.

1983 NEJM

995. A double-blind trial to assess long-term oral anticoagulant therapy in elderly patients after myocardial infarction. Report of the Sixty Plus Reinfarction Study Research Group. (PubMed)

A double-blind trial to assess long-term oral anticoagulant therapy in elderly patients after myocardial infarction. Report of the Sixty Plus Reinfarction Study Research Group. In a randomised double-blind multicentre clinical trial the effect of continued oral anticoagulant therapy after a myocardial infarction was assessed in a group of patients over 60 years of age. Half of the 878 patients who had been on anticoagulants ever since their primary myocardial infarction received placebos (...) treated group (p = 0.0001). The incidence of intracranial events was 5.6% in the placebo group and 3.1% in the group on anticoagulants (p = 0.18). Major haemorrhagic episodes were reported by 3 placebo patients and by 27 patients treated with anticoagulants. No fatal extracranial haemorrhages were seen. In this selected group of elderly patients, continuation of intensive and stable oral anticoagulant therapy substantially reduced the risk of recurrent myocardial infarction and thereby of cardiac

1980 Lancet

996. Clinical effects of vitamin C in elderly inpatients with low blood-vitamin-C levels. (PubMed)

Clinical effects of vitamin C in elderly inpatients with low blood-vitamin-C levels. The effect of oral vitamin C has been examined in elderly long-stay inpatients known to have low levels of vitamin C in their plasma and leucocytes. 1 g of vitamin C given daily for 28 days was shown to be associated with slight, but significant, clinical improvement and weight-gain when compared with placebo therapy.

1979 Lancet

997. Glucose intolerance during diuretic therapy. Results of trial by the European Working Party on Hypertension in the Elderly. (PubMed)

Glucose intolerance during diuretic therapy. Results of trial by the European Working Party on Hypertension in the Elderly. 119 elderly, hypertensive patients were followed-up for 1 year and 48 for 2 years in a double-blind, randomised, controlled trial in which they received either placebo or 25-50 mg hydrochlorothiazide and 50-100 mg of triamterene daily. Half of the active treatment group also received 250 mg to 2 g methyldopa daily. After 2 years the active treatment group had an average

1978 Lancet

998. Elective inguinal herniorrhaphy versus truss in the elderly

Elective inguinal herniorrhaphy versus truss in the elderly Elective inguinal herniorrhaphy versus truss in the elderly Elective inguinal herniorrhaphy versus truss in the elderly Neuhauser D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn (...) ) For mild/no symptomology it is unknown whether any intervention is appropriate. Bibliographic details Neuhauser D. Elective inguinal herniorrhaphy versus truss in the elderly. In: Bunker J P, Barnes B A, Mosteller F (eds). Costs, risks and benefits of surgery. New York, NY, USA: Oxford University Press. 1977 Indexing Status Subject indexing assigned by CRD MeSH Adult; Aged; Costs and Cost Analysis; Hernia, Inguinal /economics /surgery; Trusses /economics /therapeutic use AccessionNumber 21995005220

1977 NHS Economic Evaluation Database.