Latest & greatest articles for endometriosis

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Top results for endometriosis

61. Survivin and VEGF as Novel Biomarkers in Diagnosis of Endometriosis (Full text)

Survivin and VEGF as Novel Biomarkers in Diagnosis of Endometriosis The aim of this study was to investigate the role of peripheral blood markers as additional diagnostic tools to transvaginal ultrasound (TVU) findings in the diagnosis of endometriosis.This study included 40 patients undergoing laparoscopy for suspected endometriosis from January to December 2012. Preoperative levels of serum CA125, CA19-9, CEA and mRNA expression levels for survivin and VEGF were obtained. Real-time PCR (...) was used to determine relative gene expression. A new diagnostic score was obtained by deploying the peripheral blood markers to the TVU findings. Statistical methods used were Chi-square, Fisher's, Student's t-test or the Mann - Whitney test.There was a statistically significant difference in serum CA125, survivin and VEGF levels in patients with endometriosis and those without endometriosis (p<0.001, p=0.025 and p=0.009, respectively). False negative TVU findings were noted in 3/13 patients (23.1

2015 Journal of medical biochemistry PubMed

62. Urinary biomarkers for the non-invasive diagnosis of endometriosis. (Full text)

Urinary biomarkers for the non-invasive diagnosis of endometriosis. About 10% of reproductive-aged women suffer from endometriosis which is a costly chronic disease that causes pelvic pain and subfertility. Laparoscopy is the 'gold standard' diagnostic test for endometriosis, but it is expensive and carries surgical risks. Currently, there are no simple non-invasive or minimally-invasive tests available in clinical practice that accurately diagnoses endometriosis.1. To provide summary estimates (...) of the diagnostic accuracy of urinary biomarkers for the diagnosis of pelvic endometriosis compared to surgical diagnosis as a reference standard.2. To assess the diagnostic utility of biomarkers that could differentiate ovarian endometrioma from other ovarian masses.Urinary biomarkers were evaluated as replacement tests for surgical diagnosis and as triage tests to inform decisions to undertake surgery for endometriosis.The searches were not restricted to particular study design, language or publication dates

2015 Cochrane PubMed

63. A Systematic Review of the Association Between Psychiatric Disturbances and Endometriosis. (PubMed)

A Systematic Review of the Association Between Psychiatric Disturbances and Endometriosis. An association between endometriosis and psychiatric disturbances has been identified by some researchers. The purpose of this systematic review was to consolidate existing empirical findings to clarify the association between endometriosis and psychiatric conditions.We searched three electronic databases (Medline/PubMed, PsychInfo, and ClinicalTrials.gov) using the following search items: "endometriosis (...) " combined with "mood," "bipolar disorder," "major depressive disorder," "anxiety," "psychiatric," "psychosocial," "antidepressants," "antianxiety," "pharmacotherapy," or "psychotherapy."We included all relevant articles published in English. We identified 18 original research studies examining the association between endometriosis and psychiatric symptoms, with a combined total of 999 endometriosis patients being examined.Of the 18 studies examined, 14 reported that endometriosis was associated

2015 Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC

64. Initiation of GnRH agonist treatment on 3-5 days postoperatively in endometriosis patients: a randomized controlled trial (PubMed)

Initiation of GnRH agonist treatment on 3-5 days postoperatively in endometriosis patients: a randomized controlled trial Seventy patients with stage III or IV endometriosis were randomly assigned to 2 groups after conservative surgery. Group O (n = 35) received 3 cycles of a 28-day gonadotropin-releasing hormone agonist (GnRH-a) treatment (goserelin, 3.6 mg) starting 3-5 days postoperatively. Group M (n = 35) received the same treatment starting on days 1-5 of menstruation. Groups were further (...) time in group M was much longer that than that in group O (P =.001), and the bleeding rate in group M was significantly higher than that in group O (P =.024, RR = 1.185). In patients with stage III or IV endometriosis, the efficacy of GnRH-a initiated 3-5 days postoperatively was equivalent to that of GnRH-a initiated on days 1-5 of menstruation. Female patients who initiated GnRH-a treatment 3-5 days postoperatively experienced less uterine bleeding during the first cycle of treatment.© 2015

2015 EvidenceUpdates

65. Hormone Therapy for the Menopause after Endometriosis Surgery – Friend or Foe?

Hormone Therapy for the Menopause after Endometriosis Surgery – Friend or Foe? Hormone Therapy for the Menopause after Endometriosis Surgery - Friend or Foe? - Evidently Cochrane Search and hit Go By March 12, 2015 // In today’s guest blog, Dr Martin Hirsch explains about endometriosis and treatment choices for women who have the menopause induced because of it. It’s Menopause Week here at Evidently Cochrane and as a team including individual bloggers, Cochrane UK, Healthtalk and Menopause UK (...) with their NHS Change Day campaign to ‘Change the Change’, we are summarising the evidence surrounding the menopause to ensure women get the correct facts from reliable evidence. This blog aims to help women who have had the menopause induced through surgery for endometriosis make more informed health decisions at a time of significant change for their mind and body. Endometriosis – what is it and how do I know if I have it? Most women have heard of the menopause. They fear it, but for a select few women

2015 Evidently Cochrane

66. Interventions effective for endometriosis

Interventions effective for endometriosis Interventions effective for endometriosis | Cochrane Primary Care Trusted evidence. Informed decisions. Better health. Enter terms Interventions effective for endometriosis Cochrane Trusted evidence. Informed decisions. Better health. Copyright © 2019 The Cochrane Collaboration | | We use cookies to improve your experience on our site.

2014 Cochrane PEARLS

67. Laparoscopic surgery for endometriosis. (PubMed)

Laparoscopic surgery for endometriosis. Endometriosis is the presence of endometrial glands or stroma in sites other than the uterine cavity and is associated with pain and subfertility. Surgical interventions aim to remove visible areas of endometriosis and restore the anatomy.To assess the effectiveness and safety of laparoscopic surgery in the treatment of painful symptoms and subfertility associated with endometriosis.This review has drawn on the search strategy developed by the Cochrane (...) Menstrual Disorders and Subfertility Group including searching CENTRAL, MEDLINE, EMBASE, PsycINFO, and trial registries from inception to July 2013.Randomised controlled trials (RCTs) were selected in which the effectiveness and safety of laparoscopic surgery used to treat pain or subfertility associated with endometriosis was compared with any other laparoscopic or robotic intervention, holistic or medical treatment or diagnostic laparoscopy only.Selection of studies, assessment of trial quality

2014 Cochrane

68. Endometriosis: tackling pain and subfertility

Endometriosis: tackling pain and subfertility Endometriosis: tackling pain and subfertility | Evidently Cochrane sharing the latest Cochrane Reviews Search Main menu Post navigation by If you’re a woman living with endometriosis, the chances are you’ll be coping with chronic pain, and you may be facing fertility problems too. Here we look at a new overview of Cochrane systematic reviews, which brings together the best available evidence on treatments for these two devastating aspects (...) of endometriosis. Credit: Asuncion Bassas- Mujtaba, Wellcome Images It’s , which aims to raise awareness of ‘the invisible disease’, which affects around 176 million girls and women worldwide. It can have a huge impact on the lives of these women. Along with other symptoms, it can cause severe pain and fertility problems. With no available cure, treatment is directed at managing symptoms and trying to limit the effects of the disease. Treatments for pain include medical approaches, such as hormone treatments

2014 Evidently Cochrane

69. Endometriosis: tackling pain and subfertility

Endometriosis: tackling pain and subfertility Endometriosis: tackling pain and subfertility | Evidently Cochrane sharing the latest Cochrane Reviews Search Main menu Post navigation by If you’re a woman living with endometriosis, the chances are you’ll be coping with chronic pain, and you may be facing fertility problems too. Here we look at a new overview of Cochrane systematic reviews, which brings together the best available evidence on treatments for these two devastating aspects (...) of endometriosis. Credit: Asuncion Bassas- Mujtaba, Wellcome Images It’s , which aims to raise awareness of ‘the invisible disease’, which affects around 176 million girls and women worldwide. It can have a huge impact on the lives of these women. Along with other symptoms, it can cause severe pain and fertility problems. With no available cure, treatment is directed at managing symptoms and trying to limit the effects of the disease. Treatments for pain include medical approaches, such as hormone treatments

2014 Evidently Cochrane

70. Endometriosis: tackling pain and subfertility

Endometriosis: tackling pain and subfertility Endometriosis: tackling pain and subfertility - Evidently Cochrane Search and hit Go By March 20, 2014 // Credit: Asuncion Bassas- Mujtaba, Wellcome Images It’s , which aims to raise awareness of ‘the invisible disease’, which affects around 176 million girls and women worldwide. It can have a huge impact on the lives of these women. Along with other symptoms, it can cause severe pain and fertility problems. With no available cure, treatment (...) is directed at managing symptoms and trying to limit the effects of the disease. Treatments for pain include medical approaches, such as hormone treatments, with or without surgery. For women with fertility problems associated with endometriosis, drug treatments, surgery and assisted reproductive technologies (ART) may all be considered. Overviews can really help if you are making decisions about treatments, as they bring together in one place the best evidence we have, summarising systematic reviews

2014 Evidently Cochrane

71. Endometriosis: tackling pain and subfertility

Endometriosis: tackling pain and subfertility Endometriosis: tackling pain and subfertility | Evidently Cochrane sharing the latest Cochrane Reviews Search Main menu Post navigation by If you’re a woman living with endometriosis, the chances are you’ll be coping with chronic pain, and you may be facing fertility problems too. Here we look at a new overview of Cochrane systematic reviews, which brings together the best available evidence on treatments for these two devastating aspects (...) of endometriosis. Credit: Asuncion Bassas- Mujtaba, Wellcome Images It’s , which aims to raise awareness of ‘the invisible disease’, which affects around 176 million girls and women worldwide. It can have a huge impact on the lives of these women. Along with other symptoms, it can cause severe pain and fertility problems. With no available cure, treatment is directed at managing symptoms and trying to limit the effects of the disease. Treatments for pain include medical approaches, such as hormone treatments

2014 Evidently Cochrane

72. Endometriosis: an overview of Cochrane Reviews. (Full text)

Endometriosis: an overview of Cochrane Reviews. This overview reports on interventions for pain relief and for subfertility in pre-menopausal women with clinically diagnosed endometriosis.The objective of this overview was to summarise the evidence from Cochrane systematic reviews on treatment options for women with pain or subfertility associated with endometriosis.Published Cochrane systematic reviews reporting pain or fertility outcomes in women with clinically diagnosed endometriosis were (...) cases the evidence was of low or very low quality. Anti-TNF-α drugs One review found no evidence of a difference in effectiveness between anti-TNF-α drugs and placebo. However, the evidence was of low quality. Reviews reporting fertility outcomes (8 reviews) Medical interventions Four reviews reported on medical interventions for improving fertility in women with endometriosis. One compared three months of GnRH agonists with a control in women undergoing assisted reproduction and found very low

2014 Cochrane PubMed

73. Treatment of pelvic pain associated with endometriosis: a committee opinion

Treatment of pelvic pain associated with endometriosis: a committee opinion Treatment of pelvic pain associated with endometriosis: a committee opinion The Practice Committee of the American Society for Reproductive Medicine American Society for Reproductive Medicine, Birmingham, Alabama Pain associated with endometriosis may involve many mechanisms and requires careful evaluation to con?rm the diagnosis and exclude other potential causes. Both medical and surgical treatments for pain related (...) to endo- metriosisareeffective,andchoiceoftreatmentmustbeindividualized.Thisdocumentreplaces the document by the same name last published in 2008 (Fertil Steril 2008;90:S260–9). (Fertil Steril 2014;101:927–35.2014 by American Society for Reproductive Medicine.) Discuss: You candiscuss thisarticlewithits authorsandwithotherASRM membersat http:// fertstertforum.com/asrmpraccom-pelvic-pain-endometriosis/ Use your smartphone to scan this QR code and connect to the discussion forum for this article now

2014 Society for Assisted Reproductive Technology

74. Endometriosis

Endometriosis Endometriosis - NICE CKS Clinical Knowledge Summaries Share Endometriosis: Summary Endometriosis is the presence of tissue resembling endometrial glands and stroma outside the uterine cavity, which induces a chronic inflammatory reaction. It is often associated with dysmenorrhoea, pelvic pain, and subfertility. Most deposits occur in the pelvis, and this ectopic tissue is oestrogen-dependent and responds to the hormonal changes of the menstrual cycle. If the ovaries are affected (...) , ovarian cysts (endometriomas) may develop. Subfertility may be due to distortion of pelvic anatomy due to adhesions or endometriomas, or disturbance of reproductive processes. Endometriosis is most commonly diagnosed in women between 30 and 40 years of age, and is uncommon in those younger than 20 years of age. The following signs and symptoms may indicate the presence of endometriosis. Symptoms typically start after several years of painless periods. Cyclical or chronic pelvic pain, usually before

2014 NICE Clinical Knowledge Summaries

75. Caesarean section and risk for endometriosis: a prospective cohort study of Swedish registries (Full text)

Caesarean section and risk for endometriosis: a prospective cohort study of Swedish registries To investigate the association between caesarean section and later endometriosis.A prospective cohort study.The Swedish Patient Register (PAR) and the Swedish Medical Birth Registry (MBR).Women who were delivered in Sweden between 1986 and 2004.Women with the diagnosis of endometriosis, defined as codes 617 (International Classification of Diseases, ninth revision, ICD-9) or N80 (ICD-10), were (...) retrieved from the PAR. Obstetric outcome was assessed through linkage with the MBR. Out of 709,090 women, 3110 were treated as inpatients with a first diagnosis of endometriosis after their first delivery. Women with a diagnosis of endometriosis before their first delivery were excluded. Cox analyses were performed to obtain hazard ratios for endometriosis and adjusted for maternal age at first delivery, body mass index, maternal smoking, and years of involuntary childlessness at study entry. Kaplan

2013 EvidenceUpdates PubMed

76. Laparoscopic CO2 laser ablation for endometriosis

Laparoscopic CO2 laser ablation for endometriosis Laparoscopic CO2 laser ablation for endometriosis Laparoscopic CO2 laser ablation for endometriosis Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Laparoscopic CO2 laser ablation for endometriosis. Lansdale: HAYES, Inc.. Directory Publication. 2013 Authors' conclusions Laparoscopic carbon dioxide (CO2) laser (...) ablation (LCLA) is a nearly bloodless surgical procedure designed to vaporize abnormal tissues, including endometriotic lesions, with minimal damage to surrounding normal tissue. The most common purpose of LCLA in endometriosis is to restore fertility and/or relieve associated pelvic pain. The LCLA technique can be part of a diagnostic and therapeutic procedure. If employed to restore fertility, LCLA enables attempts at conception right after surgery without the typical several months of delay required

2013 Health Technology Assessment (HTA) Database.

77. Anti-TNF-α treatment for pelvic pain associated with endometriosis. (Full text)

Anti-TNF-α treatment for pelvic pain associated with endometriosis. Endometriosis is a chronic, recurring condition that can develop during the reproductive years. It is characterised by the development of endometrial tissue outside the uterine cavity. It is the most common cause of pelvic pain in women. This endometrial tissue development is dependent on oestrogen produced primarily by the ovaries and, therefore, traditional management has focused on suppression of ovarian function. Mounting (...) evidence shows that altered immune function plays a crucial role in the genesis and development of endometriosis. In this review we considered modulation of the inflammation as an alternative approach.To determine the effectiveness and safety of anti-tumour necrosis factor-α (anti-TNF-α) treatment in the management of endometriosis in premenopausal women.For the first publication of this review, we searched for trials in the following databases (from their inception to August 2009): Cochrane Menstrual

2013 Cochrane PubMed

78. Guideline on the management of women with endometriosis

Guideline on the management of women with endometriosis 1 ESHRE Endometriosis Guideline Development Group September 2013 Management of women with endometriosis Guideline of the European Society of Human Reproduction and Embryology 2 Disclaimer The European Society of Human Reproduction and Embryology (hereinafter referred to as 'ESHRE') developed the current clinical practice guideline, to provide clinical recommendations to improve the quality of healthcare delivery within the European field (...) , Nap A, Prentice A, Saridogan E, Soriano D, Nelen W. ESHRE guideline: management of women with endometriosis. Hum Reprod. 2014 Mar;29(3):400-12. doi: 10.1093/humrep/det457. ESHRE guideline 3 CONTENTS Introduction 5 Guideline scope 8 Interpretation on the grades of recommendations 10 1. Diagnosis of endometriosis 11 1.1 Symptoms and signs of endometriosis 11 1.2 Clinical examination in the diagnosis of endometriosis 14 1.3 Medical technologies in the diagnosis of endometriosis 17 1.3.1 Laparoscopy

2013 European Society of Human Reproduction and Embryology

79. Postoperative levonorgestrel-releasing intrauterine system for pelvic endometriosis-related pain: a randomized controlled trial (Full text)

Postoperative levonorgestrel-releasing intrauterine system for pelvic endometriosis-related pain: a randomized controlled trial To estimate the effectiveness of a postoperative levonorgestrel-releasing intrauterine system for relieving pelvic pain in patients with endometriosis.A double-blind randomized controlled trial was conducted in 55 patients with endometriosis and moderate-to-severe dysmenorrhea (visual analog scale, greater than 50 mm) undergoing laparoscopic conservative surgery. After (...) accepted for long-term therapy after conservative surgery for patients with moderate to severe pain related to endometriosis. It can improve the patient's quality of life, including physical and mental health.

2012 EvidenceUpdates PubMed

80. Dienogest - Pain (pelvic) associated with endometriosis

Dienogest - Pain (pelvic) associated with endometriosis Common Drug Review CDEC Meeting – March 21, 2012 Notice of CDEC Final Recommendation – April 19, 2012 Page 1 of 4 © 2012 CADTH CDEC FINAL RECOMMENDATION DIENOGEST (Visanne – Bayer Inc.) Indication: Management of Pelvic Pain Associated With Endometriosis Recommendation: The Canadian Drug Expert Committee (CDEC) recommends that dienogest be listed for the management of pelvic pain associated with endometriosis in patients for whom one (...) or more less costly hormonal options are either ineffective or cannot be used. Reasons for the Recommendation: 1. In two randomized controlled trials (RCTs) included in the systematic review, dienogest was superior to placebo (study A32473), and non-inferior to leuprolide (study AU19), in reducing pelvic pain in patients with endometriosis. 2. At the submitted price, the daily drug cost of dienogest ($1.96) is less than all alternatives with a Health Canada indication for the treatment or hormonal

2012 Canadian Agency for Drugs and Technologies in Health - Common Drug Review