Latest & greatest articles for endometriosis

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on endometriosis or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on endometriosis and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for endometriosis

101. Medical Treatment of Infertility Related to Endometriosis

Medical Treatment of Infertility Related to Endometriosis Medical Treatment of Infertility Related to Endometriosis - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S21–S22 Medical Treatment of Infertility Related to Endometriosis DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article, please choose from

2010 Society of Obstetricians and Gynaecologists of Canada

102. Surgical Management of Infertility Associated With Endometriosis

Surgical Management of Infertility Associated With Endometriosis Surgical Management of Infertility Associated With Endometriosis - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 32, Issue 7, Supplement 2, Pages S19–S20 Surgical Management of Infertility Associated With Endometriosis DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. To access this article

2010 Society of Obstetricians and Gynaecologists of Canada

103. Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. (PubMed)

Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. Endometriosis is a common gynaecological condition that affects women and can lead to painful symptoms and infertility. It greatly affects women's quality of life, impacting on their careers, everyday activities, sexual and non-sexual relationships, and fertility. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used first-line treatment for endometriosis.To assess the effects of NSAIDs used (...) for the management of pain in women with endometriosis compared to placebo, other NSAIDs, other pain management drugs, or no treatment.We searched the Cochrane Menstrual Disorders and Subfertility Group Trials Register (April 2008) published in the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), MEDLINE (1966 to April 2008), EMBASE (1980 to April 2008), and the reference lists from relevant publications. Experts in the field were also contacted for information about possible

Full Text available with Trip Pro

2009 Cochrane

104. Hormone therapy for endometriosis and surgical menopause. (PubMed)

Hormone therapy for endometriosis and surgical menopause. Endometriosis is characterized by the presence of ectopic endometrial tissue that might lead to many distressing and debilitating symptoms. Despite available studies supporting standard hormone therapy for women with endometriosis and post-surgical menopause, there is still a concern that estrogens may induce a recurrence of the disease and its symptoms.This review aimed to look at pain and disease recurrence in women with endometriosis (...) who used hormone therapy for post-surgical menopause.We searched the Cochrane Menstrual Disorders and Subfertility Group Specialized Register (March 2008), Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2008, Issue 3), MEDLINE (1966 to March 2008), EMBASE (1980 to March 2008), and references lists of articles. Relevant journals and conference proceedings were handsearched.Randomized controlled trials studying hormone therapy for women with endometriosis in post

2009 Cochrane

105. Laparoscopic management of endometriosis: comprehensive review of best evidence

Laparoscopic management of endometriosis: comprehensive review of best evidence Laparoscopic management of endometriosis: comprehensive review of best evidence Laparoscopic management of endometriosis: comprehensive review of best evidence Yeung PP, Shwayder J, Pasic RP CRD summary The authors found that laparoscopic treatment of endometriosis reduced pain and improved fertility. Co-interventions that may help (in appropriate circumstances) included laparoscopic presacral neurectomy, pre (...) -operative and/or postoperative hormonal suppression, excisional cystectomy with mesna and/or initial circular excision and anti-adhesive barriers. Due to methodological problems in the review, particularly the failure to assess study quality, the conclusions should be regarded cautiously. Authors' objectives To assess the effectiveness of laparoscopic techniques for pain and/or fertility problems associated with endometriosis. Searching The Cochrane Library and MEDLINE were searched from 1966. Search

2009 DARE.

106. Medical treatment for rectovaginal endometriosis: what is the evidence?

Medical treatment for rectovaginal endometriosis: what is the evidence? Medical treatment for rectovaginal endometriosis: what is the evidence? Medical treatment for rectovaginal endometriosis: what is the evidence? Vercellini P, Crosignani PG, Somigliana E, Berlanda N, Barbara G, Fedele L CRD summary The authors concluded that medical treatments of women with rectovaginal endometriosis were effective for pain relief. Given that the studies were limited by size, quality and were heterogeneous (...) with regard to drug and dosage, this conclusion should be treated with caution. Authors' objectives To evaluate the efficacy of medical treatments for pain associated with rectovaginal endometriosis. Searching PubMed and EMBASE were searched for English-Language articles from January 1989 to March 2009. Search terms were reported. Bibliographies of retrieved articles and review articles, books and monographs published on endometriosis were handsearched for additional material. No attempt was made

Full Text available with Trip Pro

2009 DARE.

107. The effect of second-line surgery on reproductive performance of women with recurrent endometriosis: a systematic review

The effect of second-line surgery on reproductive performance of women with recurrent endometriosis: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

108. Systematic review of the effects of aromatase inhibitors on pain associated with endometriosis (PubMed)

Systematic review of the effects of aromatase inhibitors on pain associated with endometriosis To assess the effects of aromatase inhibitors in women symptomatic of pain with endometriosis.A systematic review of published literature.We conducted a comprehensive literature search to identify all the published observational and randomised studies evaluating the efficacy of aromatase inhibitors on pain associated with endometriosis. A combination of keywords was used to identify the maximum number (...) inhibitors in combination with GnRH analogues significantly improved pain (P < 0.0001) compared with GnRH analogues alone together with significant improvement in multidimensional patient scores (P < 0.0001). There was no significant reduction in spine or hip-bone densities.Aromatase inhibitors appear to have a promising effect on pain associated with endometriosis, but the strength of this inference is limited due to a dearth of the evidence available.

Full Text available with Trip Pro

2008 EvidenceUpdates

109. Systematic review of the effects of aromatase inhibitors on pain associated with endometriosis

Systematic review of the effects of aromatase inhibitors on pain associated with endometriosis Systematic review of the effects of aromatase inhibitors on pain associated with endometriosis Systematic review of the effects of aromatase inhibitors on pain associated with endometriosis Patwardhan S, Nawathe A, Yates D, Harrison GR, Khan KS CRD summary This review found that although aromatase inhibitors appeared to have a promising effect on pain associated with endometriosis, but due (...) to the paucity of good quality evidence, the strength of the inference was limited. The review was well conducted and the authors' conclusions are likely to be reliable. Authors' objectives To evaluate the effects of aromatase inhibitors in women with symptoms of pain with endometriosis. Searching MEDLINE, EMBASE, CINAHL and the Cochrane Library were searched from inception to 2007 for relevant published studies, using a combination of keywords (not reported). Reference lists from the review and primary

Full Text available with Trip Pro

2008 DARE.

110. [Evaluation of pain and depression in women with endometriosis after a multi- professional group intervention]. (PubMed)

[Evaluation of pain and depression in women with endometriosis after a multi- professional group intervention]. Evaluate pain and depression scores before and after multi-professional group intervention in women with endometriosis as compared to those who did not participate in this activity.A total of 128 women attended at the Endometriosis Outpatient Facility CAISM/UNICAMP, was assessed and distributed equally into two groups: women who received group intervention and those who did not. All (...) pain and depression in women with endometriosis and may be included in the conventional treatment for patients affected by this disease.

2007 Revista da Associacao Medica Brasileira (1992)

111. Danazol for pelvic pain associated with endometriosis. (PubMed)

Danazol for pelvic pain associated with endometriosis. Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of ectopic endometrium. The observation that hyper androgenic states (an excess of male hormone) induce atrophy of the endometrium has led to the use of androgens in the treatment of endometriosis. Danazol is one (...) of these treatments. The efficacy of danazol is based on its ability to produce a high androgen and low oestrogen environment (a pseudo menopause) which results in atrophy of the endometriotic implants and thus an improvement in painful symptoms.To determine the effectiveness of danazol compared to placebo or no treatment in the treatment of the symptoms and signs, other than infertility, of endometriosis in women of reproductive age.We searched the Cochrane Menstrual Disorders and Subfertility Group Specialised

2007 Cochrane

112. Ovulation suppression for endometriosis. (PubMed)

Ovulation suppression for endometriosis. Endometriosis is the finding of endometrial glands or stroma in sites other than the uterine cavity. Endometriosis appears to be an oestrogen dependent condition. This hormonal dependency has prompted the therapeutic use of ovulation suppression agents, in an effort to improve subsequent fertility.To assess the effectiveness of ovulation suppression agents, including danazol, progestins and oral contraceptives, in the treatment of endometriosis (...) or a GnRH with oral contraception in women with endometriosis. A total of twenty three RCTs comparing an ovulation suppression agent with placebo or no treatment, or a suppressive agent with danazol or a GnRH with oral contraception were identified.Two review authors independently extracted data and assessed quality. We contacted study authors for additional information. Quality was assessed by of method of randomization,allocation concealment, blinding, completeness of follow-up, presence or absence

2007 Cochrane

113. WITHDRAWN: Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. (PubMed)

WITHDRAWN: Gonadotrophin-releasing hormone analogues for pain associated with endometriosis. Endometriosis is a common gynaecological condition that frequently presents with the symptom of pain. The precise pathogenesis (mode of development) of endometriosis is unclear but it is evident that endometriosis arises by the dissemination of endometrium to ectopic sites and the subsequent establishment of deposits of ectopic endometrium. The observation that endometriosis is rarely seen in the hypo (...) to non stimulation of the ovary).To determine the effectiveness of Gonadotrophin Releasing Hormone analogues (GnRHas) in the treatment of the painful symptoms of endometriosis by comparing them with no treatment, placebo, other recognised medical treatments, and surgical interventions.The search strategy of the Menstrual Disorders and Subfertility review group (please see Review Group details) was used to identify all randomised trials of the use of GnRHas for the treatment of the painful symptoms

2007 Cochrane

114. Oral contraceptives for pain associated with endometriosis. (PubMed)

Oral contraceptives for pain associated with endometriosis. Endometriosis is a common gynaecological condition which affects many women of reproductive age worldwide and is a major cause of pain and infertility. The modern oral contraceptive pill is widely used to treat pain occurring as a result of endometriosis, although the evidence for its efficacy is limited.To assess the effects of the oral contraceptive pill (OCP) in comparison to other treatments for painful symptoms of endometriosis (...) to the diagnosis of endometriosis and made visually at surgical procedure were included.Study quality assessment and data extraction were carried out independently by two review authors. One of the assessors was an expert in the content matter. We contacted study authors for additional information.Only one study met the inclusion criteria, in which a total of 57 women were allocated to two groups to compare an OCP to a GnRH analogue. Methods of randomisation and allocation concealment were unclear

2007 Cochrane

115. Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery. (PubMed)

Levonorgestrel-releasing intrauterine device (LNG-IUD) for symptomatic endometriosis following surgery. Various options exist for treating endometriosis, including ovarian suppression therapy, surgical treatment or a combination of these strategies. Surgical treatment of endometriosis sets out to remove visible areas of endometriosis and restore anatomy by division of adhesions. The aim of medical therapy is to inhibit growth of endometriotic implants by suppression of ovarian steroids (...) and induction of a hypo-estrogenic state. Postoperative treatment with a hormone-releasing intrauterine system, using levonorgestrel (LNG-IUS), has been suggested.To determine if postoperative use of an LNG-IUS in women with endometriosis improves pain symptoms associated with menstruation and reduces recurrence compared with treatment with surgery only, placebo or systemic hormones.The following databases were searched: (1) Cochrane Menstrual Disorders and Subfertility Group Specialised Register

2006 Cochrane

116. Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. (PubMed)

Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis. Women with endometriosis who are treated with in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) have a lower pregnancy rate compared to women with tubal factor infertility. It has been suggested that the administration of gonadotrophin releasing hormone (GnRH) agonists for a few months prior to IVF or ICSI increases the pregnancy rate.To determine the effectiveness (...) in original research and review articles. We contacted experts in various countries to identify unpublished trials.We included randomised controlled trials using any GnRH agonist prior to IVF or ICSI to treat women with any degree of endometriosis diagnosed by laparoscopy or laparotomyTwo independent review authors abstracted data (HNS and JGV). We sent e-mails to investigators to seek additional information. We assessed the validity of each study using the methods suggested in the Cochrane Handbook

2006 Cochrane

117. Laparoscopic helium plasma coagulation for the treatment of endometriosis

Laparoscopic helium plasma coagulation for the treatment of endometriosis Laparoscopic helium plasma coagulation for the treatment of endometriosis Laparoscopic helium plasma coagulation for the treatment of endometriosis National Institute for Health and Clinical Excellence Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation National Institute for Health (...) and Clinical Excellence. Laparoscopic helium plasma coagulation for the treatment of endometriosis. London: National Institute for Health and Clinical Excellence (NICE). Interventional Procedure Guidance 171. 2006 Authors' objectives This study aims to assess the current evidence on laparoscopic helium plasma coagulation for the treatment of endometriosis. This document replaces previous guidance on laparoscopic helium plasma coagulation of endometriosis (NICE interventional procedure guidance no. 54

2006 Health Technology Assessment (HTA) Database.

118. Laparoscopic helium plasma coagulation for the treatment of endometriosis (IPG171)

Laparoscopic helium plasma coagulation for the treatment of endometriosis (IPG171) Overview | Laparoscopic helium plasma coagulation for the treatment of endometriosis | Guidance | NICE Laparoscopic helium plasma coagulation for the treatment of endometriosis Interventional procedures guidance [IPG171] Published date: May 2006 Share Save Guidance The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland (...) on laparoscopic helium plasma coagulation for the treatment of endometriosis. It replaces the previous guidance on laparoscopic helium plasma coagulation for the treatment of endometriosis (Interventional Procedures Guidance no. 54, March 2004). As part of the NICE's work programme, the current guidance was considered for review in June 2009 but did not meet the review criteria as set out in the IP process guide. The guidance below therefore remains current. Description Laparoscopic helium plasma coagulation

2006 National Institute for Health and Clinical Excellence - Interventional Procedures

119. Non-steroidal anti-inflammatory drugs for pain in women with endometriosis. (PubMed)

Non-steroidal anti-inflammatory drugs for pain in women with endometriosis. Endometriosis is a common gynaecological condition that affects women and can lead to painful symptoms and infertility. It affects women's quality of life greatly, impacting on their careers, everyday activities, sexual and non-sexual relationships, and fertility. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used first-line treatment for endometriosis.To assess the effects of NSAIDs (...) for the management of pain in women with endometriosis compared to placebo, other NSAIDs, other pain management drugs, or no treatment.We searched the Cochrane Menstrual Disorders and Subfertility Group Specialised Trials Register (May 2005) published in the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (1966 to May 2005), EMBASE (1980 to May 2005) and the reference lists from relevant publications. Experts in the field were also contacted for information about possible studies.We included

Full Text available with Trip Pro

2005 Cochrane

120. Is helium thermal coagulator therapy for the treatment of women with minimal to moderate endometriosis cost-effective: a prospective randomised controlled trial

Is helium thermal coagulator therapy for the treatment of women with minimal to moderate endometriosis cost-effective: a prospective randomised controlled trial Is helium thermal coagulator therapy for the treatment of women with minimal to moderate endometriosis cost-effective: a prospective randomised controlled trial Is helium thermal coagulator therapy for the treatment of women with minimal to moderate endometriosis cost-effective: a prospective randomised controlled trial Lalchandani S (...) an ionised plasma beam or corona-type flame, the energy from which is delivered to the patient's target tissue via a probe. Type of intervention Treatment for endometriosis. Economic study type Cost-effectiveness analysis. Study population The study population comprised women presenting to a gynaecology outpatient clinic with a history of pelvic pain, dysmenorrhoea, dyspareunia, and dyschesia suggestive of endometriosis, or who had previously been diagnosed with the disease. Patients were excluded

2005 NHS Economic Evaluation Database.