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Latest & greatest articles for fatigue
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Pharmacological treatments for fatigue associated with palliative care. This review updates the original review, 'Pharmacological treatments for fatigue associated with palliative care' and also incorporates the review 'Drug therapy for the management of cancer-related fatigue'.In healthy individuals, fatigue is a protective response to physical or mental stress, often relieved by rest. By contrast, in palliative care patients' fatigue can be severely debilitating and is often not counteracted (...) with rest, thereby impacting daily activity and quality of life. Fatigue frequently occurs in patients with advanced disease (e.g. cancer-related fatigue) and modalities used to treat cancer can often contribute. Further complicating issues are the multidimensionality, subjective nature and lack of a consensus definition of fatigue. The pathophysiology is not fully understood and evidence-based treatment approaches are needed.To evaluate the efficacy of pharmacological treatments for fatigue
Weakness / Fatigue Scottish Palliative Care Guidelines - Weakness / Fatigue Scottish Palliative Care Guidelines search / / / Weakness / Fatigue Weakness / Fatigue Introduction Fatigue is a persistent, subjective feeling of tiredness, weakness or lack of energy related to advanced chronic illness. It has many contributory causes though the exact aetiology is poorly understood. Patients may use many terms to describe their experience of fatigue. Fatigue is a common symptom in progressive chronic (...) disease. The severity and impact of fatigue may change in the course of the disease trajectory. It is frequently regarded as more distressing than pain by patients. It is often under-recognised by professionals. Fatigue may be unrelated to level of activity and not fully alleviated by rest or sleep. It is multidimensional affecting physical function, cognitive ability, social, emotional and spiritual wellbeing. Reduced physical function limits participation in preferred activities and activities
Tiredness/fatigue in adults Tiredness/fatigue in adults - NICE CKS Clinical Knowledge Summaries Share Tiredness/fatigue in adults: Summary Tiredness (or fatigue) is often described as a lack of, or decreased, energy, and physical or mental exhaustion. Tiredness may be due to psychological, psychosocial, physical, or physiological causes or a combination of these. Between 10–18% of people in the UK report having tiredness lasting 1 month or longer, and 1.5% of people consult their GP with a new (...) Institute for Health and Clinical Excellence (NICE) uses the term chronic fatigue syndrome (CFS)/myalgic encephalomyelitis or encephalopathy (ME) however, for the purposes of this CKS topic, this will be referred to as chronic fatigue syndrome (CFS) . In adults, CFS should be considered if both of the following criteria are met: Fatigue that is persistent (for 4 months or longer) or recurrent; new or had a specific onset (not lifelong); unexplained by other conditions; has resulted in a substantial
A lifestyle intervention improves fatigue, mental health and social support among adolescents and young adults with cerebral palsy: Focus on mediating effects To evaluate the effect of a lifestyle intervention on fatigue, participation, quality of life, gross motor functioning, motivation, self-efficacy and social support, and to explore mediating effects of physical behavior and physical fitness.A randomized controlled trial with intention to treat analysis.Rehabilitation centers in university (...) hospitals in the Netherlands.Adolescents and young adults with spastic cerebral palsy.A six-month lifestyle intervention that consisted of physical fitness training combined with counseling sessions focused on physical behavior and sports participation.Fatigue, social participation, quality of life and gross motor functioning.The lifestyle intervention was effective in decreasing fatigue severity during the intervention (difference = -6.72, p = 0.02) and in increasing health-related quality of life
Diagnosis and treatment of myalgic encephalomyelitis/chronic fatigue syndrome Diagnosis and treatment of myalgic encephalomyelitis/chronic fatigue syndrome Diagnosis and treatment of myalgic encephalomyelitis/chronic fatigue syndrome This systematic review summarizes research on methods of diagnosing myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and benefits and harms of multiple medical and nonmedical treatments. It identifies evidence gaps and limitations to inform future (...) research. Citation This systematic review summarizes research on methods of diagnosing myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and benefits and harms of multiple medical and nonmedical treatments. It identifies evidence gaps and limitations to inform future research.. Diagnosis and treatment of myalgic encephalomyelitis/chronic fatigue syndrome. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 219. 2014 Authors' conclusions None
Graded exercise therapy for chronic fatigue syndrome RACGP - Graded exercise therapy: chronic fatigue syndrome Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP (...) Releases 2016 Media Releases 2015 Media Releases 2014 Media Releases 2013 Media Releases 2012 Media Releases Search Graded exercise therapy: chronic fatigue syndrome Graded exercise therapy: chronic fatigue syndrome Introduction CFS is primarily a disorder of young to middle-aged adults and is about twice as common in women than in men with the worldwide prevalence between 0.2% and 2.6%. Intervention Graded exercise therapy (GET). GET aims to increase the patient’s ability to undertake physical
Interventions for fatigue in peripheral neuropathy. Persistent feelings of fatigue (or subjective fatigue), which may be experienced in the absence of physiological factors, affect many people with peripheral neuropathy. A variety of interventions for subjective fatigue are available, but little is known about their efficacy or the likelihood of any adverse effects for people with peripheral neuropathy.To assess the effects of drugs and physical, psychological or behavioural interventions (...) for fatigue in adults or children with peripheral neuropathy.On 5 November 2013, we searched the Cochrane Neuromuscular Disease Group Specialized Register, CENTRAL, MEDLINE, EMBASE, CINAHL Plus, LILACS and AMED. We also searched reference lists of all studies identified for inclusion and relevant reviews, and contacted the authors of included studies and known experts in the field to identify additional published or unpublished data. We also searched trials registries for ongoing studies.We considered
The effect of relaxation therapy on autonomic functioning, symptoms and daily functioning, in patients with chronic fatigue syndrome or fibromyalgia: a systematic review To establish the effects of relaxation therapy on autonomic function, pain, fatigue and daily functioning in patients with chronic fatigue syndrome or fibromyalgia.A systematic literature study was performed. Using specific keywords related to fibromyalgia or chronic fatigue syndrome and relaxation therapy, the electronic (...) databases PubMed and Web of Science were searched. Included articles were assessed for their risk of bias and relevant information regarding relaxation was extracted. The review was conducted and reported according to the PRISMA-statement.Thirteen randomized clinical trials of sufficient quality were included, resulting in a total of 650 fibromyalgia patients (11 studies) and 88 chronic fatigue syndrome patients (3 studies). None of the studies reported effects on autonomic function. Six studies
Testing Vitamin B12 Levels in Neuropathy, Alopecia, Dizziness, and Fatigue: A Rapid Review Testing vitamin B12 levels in neuropathy, alopecia, dizziness, and fatigue: a rapid review Testing vitamin B12 levels in neuropathy, alopecia, dizziness, and fatigue: a rapid review Health Quality Ontario Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database (...) . Citation Health Quality Ontario. Testing vitamin B12 levels in neuropathy, alopecia, dizziness, and fatigue: a rapid review. Toronto: Health Quality Ontario (HQO). Rapid Review. 2014 Authors' objectives The objective of this analysis is to identify the clinical utility of testing vitamin B12 levels in cases of neuropathy, alopecia, dizziness, and fatigue. Authors' conclusions There is very low quality evidence that there is no association between vitamin B12 levels and neuropathy. There is very low
Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial Fatigue is a distressing symptom occurring in more than 60% of patients with cancer. The CNS stimulants modafinil and methylphenidate are recommended for the treatment of cancer-related fatigue, despite a limited evidence base. We aimed to evaluate the efficacy and tolerability of modafinil in the management of fatigue in patients with non-small-cell lung cancer (NSCLC).Adults (...) with advanced NSCLC and performance status of 0 to 2, who were not treated with chemotherapy or radiotherapy within the last 4 weeks, were randomly assigned to daily modafinil (100 mg on days 1 to 14; 200 mg on days 15 to 28) or matched placebo. The primary outcome was change in Functional Assessment of Chronic Illness Therapy (FACIT) -Fatigue score from baseline to 28 days, adjusted for baseline fatigue and performance status. Secondary outcomes included safety and patient-reported measures of depression
Effectiveness of Music Intervention in Ameliorating Cancer Patients` Anxiety, Depression, Pain, and Fatigue: A Meta-analysis This is the first study to use meta-analysis as a scientific technique to provide an integrated analysis of the effectiveness of music intervention in cancer patients.The purpose of this study was, using the meta-analysis method, to present a summary of existing research and explore the effectiveness of music intervention in ameliorating anxiety, depression, pain (...) , and fatigue in cancer patients.The present study collected quantitative study designs sought of music intervention for cancer patients published from 2002 to 2012. These studies were then cross-referenced using Medical Subject Headings for topics on music intervention and cancer patients. Outcome indicators were anxiety, depression, pain, and fatigue. The quality of the studies was evaluated using Cochrane Collaboration Guidelines. The effect size on outcome indicators used the formula devised by Hedges
Effectiveness of energy conservation treatment in reducing fatigue in multiple sclerosis: a systematic review and meta-analysis Effectiveness of energy conservation treatment in reducing fatigue in multiple sclerosis: a systematic review and meta-analysis Effectiveness of energy conservation treatment in reducing fatigue in multiple sclerosis: a systematic review and meta-analysis Blikman LJ, Huisstede BM, Kooijmans H, Stam HJ, Bussmann JB, van Meeteren J CRD summary This review concluded (...) that energy conservation management for fatigued patients with multiple sclerosis could have greater short-term efficacy in reducing the impact of fatigue and improving quality of life (with better scores on three out of eight questionnaire subscales) than no treatment. The authors' conclusions may not be sufficiently cautious, although their recommendation for further trials appear appropriate. Authors' objectives To assess the effects of energy conservation management treatment for fatigue in multiple
Screening, Assessment, and Management of Fatigue in Adult Survivors of Cancer Guideline Adaptation Screening, Assessment, and Management of Fatigue in Adult Survivors of Cancer: An American Society of Clinical Oncology Clinical Practice Guideline Adaptation | Journal of Clinical Oncology Search in: Menu Article Tools ASCO SPECIAL ARTICLES Article Tools OPTIONS & TOOLS COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.2013.53.4495 Journal of Clinical Oncology - published (...) online before print April 14, 2014 PMID: Screening, Assessment, and Management of Fatigue in Adult Survivors of Cancer: An American Society of Clinical Oncology Clinical Practice Guideline Adaptation x Julienne E. Bower , x Kate Bak , x Ann Berger , x William Breitbart , x Carmelita P. Escalante , x Patricia A. Ganz , x Hester Hill Schnipper , x Christina Lacchetti , x Jennifer A. Ligibel , x Gary H. Lyman , x Mohammed S. Ogaily , x William F. Pirl , x Paul B. Jacobsen Julienne E. Bower and Patricia
Effects of exercise training on fitness, mobility, fatigue, and health-related quality of life among adults with multiple sclerosis: a systematic review to inform guideline development To conduct a systematic review of evidence surrounding the effects of exercise training on physical fitness, mobility, fatigue, and health-related quality of life in adults with multiple sclerosis (MS).The databases included EMBASE, 1980 to 2011 (wk 12); Ovid MEDLINE and Ovid OLDMEDLINE, 1947 to March (wk 3) 2011 (...) ; PsycINFO, 1967 to March (wk 4) 2011; CINAHL all-inclusive; SPORTDiscus all-inclusive; Cochrane Library all-inclusive; and Physiotherapy Evidence Database all-inclusive.The review was limited to English-language studies (published before December 2011) of people with MS that evaluated the effects of exercise training on outcomes of physical fitness, mobility, fatigue, and/or health-related quality of life.One research assistant extracted data and rated study quality. A second research assistant verified
Transcutaneous electrical nerve stimulation reduces pain, fatigue and hyperalgesia while restoring central inhibition in primary fibromyalgia Because transcutaneous electrical nerve stimulation (TENS) works by reducing central excitability and activating central inhibition pathways, we tested the hypothesis that TENS would reduce pain and fatigue and improve function and hyperalgesia in people with fibromyalgia who have enhanced central excitability and reduced inhibition. The current study (...) used a double-blinded randomized, placebo-controlled cross-over design to test the effects of a single treatment of TENS with people with fibromyalgia. Three treatments were assessed in random order: active TENS, placebo TENS and no TENS. The following measures were assessed before and after each TENS treatment: pain and fatigue at rest and in movement; pressure pain thresholds, 6-m walk test, range of motion; 5-time sit-to-stand test, and single-leg stance. Conditioned pain modulation
A pragmatic parallel arm multi-centre randomised controlled trial to assess the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis A pragmatic parallel arm multi-centre randomised controlled trial to assess the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis A pragmatic parallel arm multi-centre randomised controlled trial to assess (...) the effectiveness and cost-effectiveness of a group-based fatigue management programme (FACETS) for people with multiple sclerosis Thomas S, Thomas PW, Kersten P, Jones R, Green C, Nock A, Slingsby V, Smith AD, Baker R, Galvin KT, Hillier C Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study
What’s the evidence on tackling fatigue in rheumatoid arthritis? What’s the evidence on tackling fatigue in rheumatoid arthritis? | Evidently Cochrane sharing the latest Cochrane Reviews Search Main menu Post navigation by Key message: There is some evidence that physical activity and talking treatments can help people with rheumatoid arthritis manage fatigue. We don’t have enough evidence to say which elements of these types of interventions are most effective, nor whether other non-drug (...) approaches are also helpful. Rheumatoid arthritis (RA) is an autoimmune disease that causes inflammation of the joints. It’s the second most common type of arthritis in the UK population. Key symptoms are painful, swollen joints, but fatigue (extreme mental and/or physical tiredness) is also a problem for many people who have RA. There’s currently no cure for RA and no accepted evidence-based guidelines on how best to manage this condition. Non-pharmacological interventions, that’s alternatives