Latest & greatest articles for fibromyalgia

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Top results for fibromyalgia

101. Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia syndrome. (PubMed)

Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia syndrome. Fibromyalgia syndrome (FMS) is a clinically well-defined chronic condition of unknown etiology characterized by chronic widespread pain that often co-exists with sleep disturbances, cognitive dysfunction and fatigue. Patients often report high disability levels and poor quality of life (QOL). Drug therapy focuses on reducing key symptoms and improving quality of life.To assess the benefits and harms of serotonin

2013 Cochrane

102. Randomised controlled trial: Telephone-based cognitive-behavioural therapy and a structured exercise programme are effective for chronic widespread pain (fibromyalgia)

Randomised controlled trial: Telephone-based cognitive-behavioural therapy and a structured exercise programme are effective for chronic widespread pain (fibromyalgia) Telephone-based cognitive-behavioural therapy and a structured exercise programme are effective for chronic widespread pain (fibromyalgia) | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn (...) are effective for chronic widespread pain (fibromyalgia) Article Text Therapeutics Randomised controlled trial Telephone-based cognitive-behavioural therapy and a structured exercise programme are effective for chronic widespread pain (fibromyalgia) Kurt Kroenke Correspondence to : Kurt Kroenke Indiana University School of Medicine, 1050 Wishard Blvd, Regenstrief Institute, 5th Floor, Indianapolis, Indiana 46202, USA; kkroenke{at}regenstrief.org Statistics from Altmetric.com Commentary on: McBeth J

2013 Evidence-Based Medicine (Requires free registration)

103. Small benefit from cognitive behavioural therapies for fibromyalgia

Small benefit from cognitive behavioural therapies for fibromyalgia Small benefit from cognitive behavioural therapies for fibromyalgia | Cochrane Primary Care Trusted evidence. Informed decisions. Better health. Enter terms Small benefit from cognitive behavioural therapies for fibromyalgia Cochrane Trusted evidence. Informed decisions. Better health. Copyright © 2019 The Cochrane Collaboration | | We use cookies to improve your experience on our site.

2013 Cochrane PEARLS

104. The cost-effectiveness of pregabalin in the treatment of fibromyalgia: US perspective

The cost-effectiveness of pregabalin in the treatment of fibromyalgia: US perspective The cost-effectiveness of pregabalin in the treatment of fibromyalgia: US perspective The cost-effectiveness of pregabalin in the treatment of fibromyalgia: US perspective Lloyd A, Boomershine CS, Choy EH, Chandran A, Zlateva G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results (...) and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study examined the cost-effectiveness of pregabalin for treatment of severe fibromyalgia compared with placebo, duloxetine, milnacipran, gabapentin, tramadol and amitriptyline. The authors concluded that pregabalin was more beneficial and less expensive than the other available treatments for severe fibromyalgia, except when compared to amitriptyline. The study used valid

2012 NHS Economic Evaluation Database.

105. Effect of pregabalin on sleep in patients with fibromyalgia and sleep maintenance disturbance: a randomized, placebo-controlled, 2-way crossover polysomnography study (PubMed)

Effect of pregabalin on sleep in patients with fibromyalgia and sleep maintenance disturbance: a randomized, placebo-controlled, 2-way crossover polysomnography study To assess the effect of pregabalin on polysomnographic (PSG) measures of sleep and patient-rated sleep, tiredness, and pain in fibromyalgia patients.We performed a randomized, double-blind, placebo-controlled, 2-period crossover PSG study. Patients ages ≥18 years with fibromyalgia satisfied subjective and objective sleep (...) score improved (decreased) with pregabalin versus placebo treatment at all 4 weeks (week 4 difference: -0.52 [95% CI -0.90, -0.14]; P = 0.0084). Modest (ρ = <0.3) but significant correlations were found between PSG sleep assessments and ratings of pain and sleep quality. Frequently reported all-causality adverse events (pregabalin versus placebo) were: dizziness (30.4% versus 9.9%), somnolence (20.5% versus 4.5%), and headache (8.9% versus 8.1%).Patients with fibromyalgia treated with pregabalin had

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2012 EvidenceUpdates

106. Phenytoin for neuropathic pain and fibromyalgia in adults. (PubMed)

Phenytoin for neuropathic pain and fibromyalgia in adults. Antiepileptic drugs have been used in pain management since the 1960s; some have shown efficacy in treating different neuropathic pain conditions. Phenytoin is an established antiepileptic drug that has been used occasionally to treat intractable trigeminal neuralgia.To assess the analgesic efficacy and adverse effects of the antiepileptic drug phenytoin in neuropathic pain and fibromyalgia.We searched the Cochrane Central Register (...) quality.We did not identify any studies that satisfied the inclusion criteria.This review uncovered no evidence of sufficient quality to support the use of phenytoin in chronic neuropathic pain or fibromyalgia.

2012 Cochrane

107. Clonazepam for neuropathic pain and fibromyalgia in adults. (PubMed)

Clonazepam for neuropathic pain and fibromyalgia in adults. Antiepileptic drugs have been used in pain management since the 1960s; some have shown efficacy in treating different neuropathic pain conditions. Clonazepam, a benzodiazepine, is an established antiepileptic drug, but its place in the treatment of neuropathic pain is unclear.To assess the analgesic efficacy and adverse effects of the antiepileptic drug clonazepam in neuropathic pain and fibromyalgia.We searched the Cochrane Central (...) of study quality.We did not identify any studies that satisfied the inclusion criteria.This review uncovered no evidence of sufficient quality to support the use of clonazepam in chronic neuropathic pain or fibromyalgia.

2012 Cochrane

108. Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome. (PubMed)

Monoamine oxidase inhibitors (MAOIs) for fibromyalgia syndrome. Fibromyalgia (FM) syndrome is a chronic condition of unknown aetiology characterised by musculoskeletal pain that often co-exists with sleep disturbance, cognitive dysfunction and fatigue. Patients often report high disability levels and poor quality of life. Since there is no specific treatment that alters the pathogenesis of FM, drug therapy focuses on pain reduction and improvement of other bothersome symptoms.The objective

2012 Cochrane

109. Multicomponent cognitive-behavioral group therapy with hypnosis for the treatment of fibromyalgia: long-term outcome (PubMed)

Multicomponent cognitive-behavioral group therapy with hypnosis for the treatment of fibromyalgia: long-term outcome This study compared the efficacy of 2 psychological treatments for fibromyalgia with each other and with standard care. Ninety-three patients with fibromyalgia (FM) were randomly assigned to 1 of the 3 experimental conditions: 1) multicomponent cognitive-behavioral therapy (CBT); 2) multicomponent CBT with hypnosis; and 3) pharmacological treatment (standard care control group (...) in a multicomponent cognitive-behavioral group treatment of fibromyalgia patients. Also, this research showed that by adding hypnosis the length of treatment did not increase.Copyright © 2012 American Pain Society. Published by Elsevier Inc. All rights reserved.

2012 EvidenceUpdates

110. Cognitive behavioral therapy for the treatment of juvenile fibromyalgia: a multisite, single-blind, randomized, controlled clinical trial (PubMed)

Cognitive behavioral therapy for the treatment of juvenile fibromyalgia: a multisite, single-blind, randomized, controlled clinical trial Juvenile fibromyalgia syndrome (FMS) is a chronic musculoskeletal pain disorder in children and adolescents for which there are no evidence-based treatments. The objective of this multisite, single-blind, randomized clinical trial was to test whether cognitive-behavioral therapy (CBT) was superior to fibromyalgia (FM) education in reducing functional

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2012 EvidenceUpdates

111. Cost effectiveness of duloxetine in the treatment of fibromyalgia in the United States

Cost effectiveness of duloxetine in the treatment of fibromyalgia in the United States Cost effectiveness of duloxetine in the treatment of fibromyalgia in the United States Cost effectiveness of duloxetine in the treatment of fibromyalgia in the United States Beard SM, Roskell N, Le TK, Zhao Y, Coleman A, Ang D, Lawson K Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study assessed the cost-effectiveness of duloxetine for the treatment of moderate-to-severe pain from fibromyalgia. It focused on the best position for duloxetine in the treatment sequence. The authors concluded that adding duloxetine to the treatment sequence for fibromyalgia was cost-effective, particularly when it was the second-line treatment after

2012 NHS Economic Evaluation Database.

112. The use of Yoga for the Treatment of Fibromyalgia in Adult Women

The use of Yoga for the Treatment of Fibromyalgia in Adult Women "The use of Yoga for the Treatment of Fibromyalgia in Adult Women" by Jason L. Johnston < > > > > > Title Author Date of Graduation Summer 8-11-2012 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Saje Davis-Risen, PA-C, MS Second Advisor Annjanette Sommers PA-C, MS Rights . Abstract Background: Fibromyalgia (FM) is a somewhat poorly understood and controversial pain syndrome (...) effecting approximately 5 million persons in the United States. The pathophysiology of fibromyalgia is not completely understood and traditional therapy includes pharmacologic agents of mixed effectiveness. Method: An exhaustive literature search was conducted using Medline, CINAHL, PsychINFO, EBMR multifile, and Web of Science using the search terms fibromyalgia, yoga, treatment, and adult. Reference lists from identified articles were also reviewed for additional studies. Two studies met the criteria

2012 Pacific University EBM Capstone Project

113. [Physiotherapy and physical therapies for fibromyalgia syndrome: systematic review, meta-analysis and guideline]

[Physiotherapy and physical therapies for fibromyalgia syndrome: systematic review, meta-analysis and guideline] Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

114. Ten sessions of adjunctive left prefrontal rTMS significantly reduces fibromyalgia pain: a randomized, controlled pilot study (PubMed)

Ten sessions of adjunctive left prefrontal rTMS significantly reduces fibromyalgia pain: a randomized, controlled pilot study Transcranial magnetic stimulation (TMS) of the prefrontal cortex can cause changes in acute pain perception. Several weeks of daily left prefrontal TMS has been shown to treat depression. We recruited 20 patients with fibromyalgia, defined by American College of Rheumatology criteria, and randomized them to receive 4000 pulses at 10 Hz TMS (n=10), or sham TMS (n=10 (...) ) treatment for 10 sessions over 2 weeks along with their standard medications, which were fixed and stable for at least 4 weeks before starting sessions. Subjects recorded daily pain, mood, and activity. Blinded raters assessed pain, mood, functional status, and tender points weekly with the Brief Pain Inventory, Hamilton Depression Rating Scale, and Fibromyalgia Impact Questionnaire. No statistically significant differences between groups were observed. Patients who received active TMS had a mean 29

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2011 EvidenceUpdates

115. Systematic review: Placebo response in drug trials of fibromyalgia syndrome and painful peripheral diabetic neuropathy-magnitude and patient-related predictors (PubMed)

Systematic review: Placebo response in drug trials of fibromyalgia syndrome and painful peripheral diabetic neuropathy-magnitude and patient-related predictors The magnitude of placebo response and its predictors in fibromyalgia syndrome (FMS) and painful peripheral diabetic neuropathy (DPN) had not been studied. We performed a systematic review by searching MEDLINE, CENTRAL, SCOPUS, and the databases of the U.S. National Institutes of Health and the Pharmaceutical Research and Manufacturers

2011 EvidenceUpdates

116. Effect of intravenous lidocaine associated with amitriptyline on pain relief and plasma serotonin, norepinephrine, and dopamine concentrations in fibromyalgia. (PubMed)

Effect of intravenous lidocaine associated with amitriptyline on pain relief and plasma serotonin, norepinephrine, and dopamine concentrations in fibromyalgia. The objective of this study was to evaluate the effect of intravenous lidocaine combined with amitriptyline on pain relief and plasma serotonin, norepinephrine, and dopamine levels.A prospective, randomized, double-blind comparative study was conducted in 30 patients. All patients received 25 mg amitriptyline; monotherapy group (n=15 (...) or plasma serotonin, norepinephrine, or dopamine concentrations in fibromyalgia patients.

2011 EvidenceUpdates

117. Systematic review of the comparative effectiveness of antiepileptic drugs for fibromyalgia (PubMed)

Systematic review of the comparative effectiveness of antiepileptic drugs for fibromyalgia Fibromyalgia is a difficult-to-treat chronic pain syndrome that affects 2% of the US population. Pregabalin is an antiepileptic recently FDA approved for fibromyalgia treatment. Other antiepileptics have been suggested for treatment. This systematic review examines the relative benefits and harms of antiepileptic drugs in the treatment of fibromyalgia. A literature search was conducted and 8 studies (...) or harmful than the other, although limited evidence suggests potential differences. Future studies must directly compare the drugs, include a more broadly defined population, examine long term benefits and harms, and include cointerventions. We conclude that pregabalin and gabapentin are modestly effective for the treatment of fibromyalgia but that their long-term safety and efficacy remain unknown.This systematic review evaluates the benefits and harms of using the antiepileptic drugs gabapentin

2011 EvidenceUpdates

118. Comparative efficacy and acceptability of amitriptyline, duloxetine and milnacipran in fibromyalgia syndrome: a systematic review with meta-analysis (PubMed)

Comparative efficacy and acceptability of amitriptyline, duloxetine and milnacipran in fibromyalgia syndrome: a systematic review with meta-analysis To evaluate and compare the efficacy and acceptability of the antidepressants amitriptyline (AMT), duloxetine (DLX) and milnacipran (MLN) for FM syndrome (FMS).Cochrane Library, MEDLINE, SCOPUS, www.clinicalstudyresults.org and www.clinicalTrials.gov were searched for randomized pharmacological placebo-controlled trials until 30 May 2010. Outcomes

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2011 EvidenceUpdates

119. Hormonal replacement therapy does not affect self-estimated pain or experimental pain responses in post-menopausal women suffering from fibromyalgia: a double-blind, randomized, placebo-controlled trial (PubMed)

Hormonal replacement therapy does not affect self-estimated pain or experimental pain responses in post-menopausal women suffering from fibromyalgia: a double-blind, randomized, placebo-controlled trial FM is a condition that preferentially affects women. Sex hormones, and in particular oestrogens, have been shown to affect pain processing and pain sensitivity, and oestrogen deficit has been considered a potentially promoting factor for FM. However, the effects of oestrogen treatment

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2011 EvidenceUpdates

120. Treating fibromyalgia with mindfulness-based stress reduction: results from a 3-armed randomized controlled trial (PubMed)

Treating fibromyalgia with mindfulness-based stress reduction: results from a 3-armed randomized controlled trial Mindfulness-based stress reduction (MBSR) is a structured 8-week group program teaching mindfulness meditation and mindful yoga exercises. MBSR aims to help participants develop nonjudgmental awareness of moment-to-moment experience. Fibromyalgia is a clinical syndrome with chronic pain, fatigue, and insomnia as major symptoms. Efficacy of MBSR for enhanced well-being (...) of fibromyalgia patients was investigated in a 3-armed trial, which was a follow-up to an earlier quasi-randomized investigation. A total of 177 female patients were randomized to one of the following: (1) MBSR, (2) an active control procedure controlling for nonspecific effects of MBSR, or (3) a wait list. The major outcome was health-related quality of life (HRQoL) 2 months post-treatment. Secondary outcomes were disorder-specific quality of life, depression, pain, anxiety, somatic complaints

2011 EvidenceUpdates