Latest & greatest articles for fibromyalgia

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on fibromyalgia or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on fibromyalgia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for fibromyalgia

141. A randomized trial of tai chi for fibromyalgia. (PubMed)

A randomized trial of tai chi for fibromyalgia. Previous research has suggested that tai chi offers a therapeutic benefit in patients with fibromyalgia.We conducted a single-blind, randomized trial of classic Yang-style tai chi as compared with a control intervention consisting of wellness education and stretching for the treatment of fibromyalgia (defined by American College of Rheumatology 1990 criteria). Sessions lasted 60 minutes each and took place twice a week for 12 weeks for each (...) of the study groups. The primary end point was a change in the Fibromyalgia Impact Questionnaire (FIQ) score (ranging from 0 to 100, with higher scores indicating more severe symptoms) at the end of 12 weeks. Secondary end points included summary scores on the physical and mental components of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). All assessments were repeated at 24 weeks to test the durability of the response.Of the 66 randomly assigned patients, the 33 in the tai chi group

Full Text available with Trip Pro

2010 NEJM

142. Which kind of exercise is best in fibromyalgia therapeutic programmes? A practical review

Which kind of exercise is best in fibromyalgia therapeutic programmes? A practical review Which kind of exercise is best in fibromyalgia therapeutic programmes? A practical review Which kind of exercise is best in fibromyalgia therapeutic programmes? A practical review Cazzola M, Atzeni F, Salaffi F, Stisi S, Cassisi G, Sarzi-Puttini P CRD summary The review found physical exercise was effective for slight to moderate improvement in aerobic fitness, functional status and quality of life (...) in fibromyalgia patients with no clear differences between programmes. These conclusions must be treated with caution due to wide variation within and unknown quality of the limited evidence base, potential bias in review processes and limited reporting of results. Authors' objectives To assess the effectiveness of different forms of physical exercise on pain and physical and mental function in people with fibromyalgia. Searching MEDLINE, EMBASE and The Cochrane Library were searched from January 1985

2010 DARE.

143. Psychological treatments for fibromyalgia: a meta-analysis

Psychological treatments for fibromyalgia: a meta-analysis Psychological treatments for fibromyalgia: a meta-analysis Psychological treatments for fibromyalgia: a meta-analysis Glombiewski JA, Sawyer AT, Gutermann J, Koenig K, Rief W, Hofmann SG CRD summary The review concluded that psychological treatments for fibromyalgia had relatively small but significant positive effects for sleep problems, depression, functional status, catastrophizing and particularly for pain. Cognitive-behavioural (...) therapy had the greatest effects. The review was generally well-performed, but the quality of the evidence and so the extent to which the authors’ conclusions are reliable is unclear. Authors' objectives To evaluate the short- and long-term efficacy and treatment moderators of psychological interventions for fibromyalgia. Searching PubMed, PsycINFO and The Cochrane Library were searched from inception to 1 January 2009 for publications in English, German, Spanish, Italian and Polish; search terms were

2010 DARE.

144. Massage therapy for fibromyalgia symptoms

Massage therapy for fibromyalgia symptoms Massage therapy for fibromyalgia symptoms Massage therapy for fibromyalgia symptoms Kalichman L CRD summary This review concluded that there was modest support for the use of massage therapy for symptom relief in patients with fibromyalgia. The review suffered from several methodological limitations, including the potential for error and bias in the search and review processes, together with the unclear quality of included studies. Consequently (...) , the reliability of the author's conclusion is uncertain. Authors' objectives To assess the effectiveness of massage therapy for symptom relief in patients with fibromyalgia. Searching PubMed, CINAHL, PsycINFO, PEDro and Web of Science databases were searched from inception to December 2009 for published studies in any language. Search terms were reported. Google Scholar was also searched. Reference lists of retrieved articles were scanned and field experts were contacted to identify further studies. Study

2010 DARE.

145. Efficacy of cognitive-behavioral therapies in fibromyalgia syndrome: a systematic review and metaanalysis of randomized controlled trials

Efficacy of cognitive-behavioral therapies in fibromyalgia syndrome: a systematic review and metaanalysis of randomized controlled trials Efficacy of cognitive-behavioral therapies in fibromyalgia syndrome: a systematic review and metaanalysis of randomized controlled trials Efficacy of cognitive-behavioral therapies in fibromyalgia syndrome: a systematic review and metaanalysis of randomized controlled trials Bernardy K, Fuber N, Kollner V, Hauser W CRD summary The review found that cognitive (...) behavioural therapy (CBT) appeared to improve coping with pain and reduced depressed mood and healthcare-seeking behaviour in individuals with fibromyalgia. In view of limitations of the review (in particular clinical, methodological and statistical heterogeneity between the studies) these conclusions should be regarded with caution. Authors' objectives To evaluate the efficacy of cognitive behavioural therapy (CBT) to treat fibromyalgia syndrome. Searching Cochrane Central Register of Controlled Trials

2010 DARE.

146. Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome

Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome Hauser W, Petzke F, Sommer C CRD summary The authors concluded that there was evidence of the short-term (up to six months) efficacy of duloxetine, milnacipran and pregabalin in fibromyalgia syndrome (...) ; the drugs differed in their effects on fibromyalgia syndrome domains and side-effects. The conclusions about the relative efficacy of drugs were not based on direct comparisons and may not be definitive. Authors' objectives To compare the efficacy and side-effects of duloxetine, milnacipran and pregabalin for the treatment of fibromyalgia syndrome. Searching MEDLINE, SCOPUS and Cochrane Central Register of Controlled Trials (CENTRAL) were searched to May 2009. Information was provided about the search

2010 DARE.

147. Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective

Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective Choy E, Richards S, Bowrin K, Watson P, Lloyd A, Sadosky A, Zlateva G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the cost-effectiveness of pregabalin versus placebo, duloxetine, gabapentin, tramadol, or amitriptyline, for the treatment of fibromyalgia. Pregabalin 450mg was consistently more cost-effective than pregabalin 300mg and both doses were cost-effective over placebo and duloxetine, for a population with severe disease. The study

2010 NHS Economic Evaluation Database.

148. Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis

Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

149. Improvements of muscle strength predicted benefits in HRQOL and postural balance in women with fibromyalgia: an 8-month randomized controlled trial (PubMed)

Improvements of muscle strength predicted benefits in HRQOL and postural balance in women with fibromyalgia: an 8-month randomized controlled trial To evaluate whether changes in muscle strength due to 32 weeks of supervised aquatic training predicted improvements on health-related quality of life (HRQOL).Thirty women with FM aged 50.8 +/- 8.7 years were randomly assigned to an experimental group (n = 15), performing 3 weekly sessions of 60 min of warm-water exercise; or to a control group (n

Full Text available with Trip Pro

2009 EvidenceUpdates

150. Low-Frequency Transcranial Magnetic Stimulation in Patients with Fibromyalgia and Major Depression (PubMed)

Low-Frequency Transcranial Magnetic Stimulation in Patients with Fibromyalgia and Major Depression To study the efficacy of low-frequency transcranial magnetic stimulation in patients with fibromyalgia and major depression.Twenty-eight patients were randomly assigned to receive 20 sessions of real or sham transcranial magnetic stimulation of the right dorsolateral prefrontal cortex. The main stimulation parameters were 15 trains at 110% of the motor threshold for 60 seconds at a frequency of 1 (...) Hz. Blinded external evaluators administered the fibromyalgia scales (FibroFatigue, Likert pain) and the depression scales (Hamilton Depression Rating Scale, Clinical Global Impression) during the study.Both treatment groups (real and sham) improved their scores in some of the scales (FibroFatigue and Clinical Global Impression), although there were no differences between them. No improvements were observed in the Likert Pain Scale in either of the groups.With the methodology used in this study

Full Text available with Trip Pro

2009 EvidenceUpdates

151. Efficacy of multicomponent treatment in fibromyalgia syndrome: A meta-analysis of randomized controlled clinical trials (PubMed)

Efficacy of multicomponent treatment in fibromyalgia syndrome: A meta-analysis of randomized controlled clinical trials To systematically review the efficacy of multicomponent treatment of fibromyalgia syndrome (FMS).We screened Medline, PsychINFO, Scopus, and the Cochrane Library (through December 2007), as well as reference sections of original studies, reviews, and evidence-based guidelines. Randomized controlled trials (RCTs) on the multicomponent treatment (at least 1 educational or other

Full Text available with Trip Pro

2009 EvidenceUpdates

152. Comparison of manual lymph drainage therapy and connective tissue massage in women with fibromyalgia: a randomized controlled trial (PubMed)

Comparison of manual lymph drainage therapy and connective tissue massage in women with fibromyalgia: a randomized controlled trial This study analyzed and compared the effects of manual lymph drainage therapy (MLDT) and connective tissue massage (CTM) in women with primary fibromyalgia (PFM).The study design was a randomized controlled trial. Fifty women with PFM completed the study. The patients were divided randomly into 2 groups. Whereas 25 of them received MLDT, the other 25 underwent CTM (...) . The treatment program was carried out 5 times a week for 3 weeks in each group. Pain was evaluated by a visual analogue scale and algometry. The Fibromyalgia Impact Questionnaire (FIQ) and Nottingham Health Profile were used to describe health status and health-related quality of life (HRQoL). Wilcoxon signed rank test and Mann-Whitney U test were used to analyze the data.In both groups, significant improvements were found regarding pain intensity, pain pressure threshold, and HRQoL (P < .05). However

2009 EvidenceUpdates

153. Treatment of fibromyalgia syndrome with antidepressants: a meta-analysis. (PubMed)

Treatment of fibromyalgia syndrome with antidepressants: a meta-analysis. Fibromyalgia syndrome (FMS) is a chronic pain disorder associated with multiple debilitating symptoms and high disease-related costs. Effective treatment options are needed.To determine the efficacy of antidepressants in the treatment of FMS by performing a meta-analysis of randomized controlled clinical trials.MEDLINE, PsycINFO, Scopus, and the Cochrane Library databases were searched through August 2008. Reference

Full Text available with Trip Pro

2009 JAMA

154. Acupuncture for the treatment of arthritis and fibromyalgia

Acupuncture for the treatment of arthritis and fibromyalgia Acupuncture for the treatment of arthritis and fibromyalgia Acupuncture for the treatment of arthritis and fibromyalgia Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Report may be purchased from . Citation Acupuncture for the treatment of arthritis and fibromyalgia . Lansdale: HAYES, Inc.. 2009 Authors (...) ' objectives Acupuncture is used as a complementary and alternative medicine (CAM) treatment for various acute or chronic pain conditions, including arthritis and fibromyalgia. The goal of acupuncture in patients with arthritis or fibromyalgia is to reduce pain and/or improve function. Project page URL Indexing Status Subject indexing assigned by CRD MeSH Acupuncture Therapy; Arthritis; Fibromyalgias Language Published English Country of organisation United States Address for correspondence 157 S. Broad

2009 Health Technology Assessment (HTA) Database.

155. Qualitative systemic review of randomized controlled trials on complementary and alternative medicine treatments in fibromyalgia

Qualitative systemic review of randomized controlled trials on complementary and alternative medicine treatments in fibromyalgia Qualitative systematic review of randomized controlled trials on complementary and alternative medicine treatments in fibromyalgia Qualitative systematic review of randomized controlled trials on complementary and alternative medicine treatments in fibromyalgia Baranowsky J, Klose P, Musial F, Haeuser W, Dobos G, Langhorst J CRD summary This review of complementary (...) and alternative medicine treatments for fibromyalgia found some positive evidence for balneotherapy and hydrotherapy. There was little or no evidence of positive effects for other interventions. The authors' conclusions appeared to appropriately consider the limitations of the studies and lack of data, but there was a risk that relevant data were missed. Authors' objectives To review the evidence from trials of different complementary and alternative medicine treatments for fibromyalgia. Searching EMBASE

Full Text available with Trip Pro

2009 DARE.

156. Assessment of the effects of aquatic therapy on global symptomatology in patients with fibromyalgia syndrome: a randomized controlled trial (PubMed)

Assessment of the effects of aquatic therapy on global symptomatology in patients with fibromyalgia syndrome: a randomized controlled trial To evaluate the effects of a 16-week exercise therapy in a chest-high pool of warm water through applicable tests in the clinical practice on the global symptomatology of women with fibromyalgia (FM) and to determine exercise adherence levels.A randomized controlled trial.Testing and training were completed at the university.Middle-aged women with FM (n=60 (...) ) and healthy women (n=25).A 16-week aquatic training program, including strength training, aerobic training, and relaxation exercises.Tender point count (syringe calibrated), health status (Fibromyalgia Impact Questionnaire); sleep quality (Pittsburgh Sleep Quality Index); physical (endurance strength to low loads tests), psychologic (State Anxiety Inventory), and cognitive function (Paced Auditory Serial Addition Task); and adherence 12 months after the completion of the study.For all the measurements

2009 EvidenceUpdates

157. Amitriptyline in the treatment of fibromyalgia: a systematic review of its efficacy (PubMed)

Amitriptyline in the treatment of fibromyalgia: a systematic review of its efficacy The objective of this study was to assess the efficacy and safety of amitriptyline as a treatment of FM. A comprehensive computerized search in Medline (Pubmed), EMBASE and The Cochrane Library was performed. Randomized controlled trials (RCTs) comparing amitriptyline vs placebo in adult patients suffering from FM were identified, the methodological quality was assessed and the results of the main outcomes were

Full Text available with Trip Pro

2009 EvidenceUpdates

158. Efficacy of multicomponent treatment in fibromyalgia syndrome: a meta-analysis of randomized controlled clinical trials

Efficacy of multicomponent treatment in fibromyalgia syndrome: a meta-analysis of randomized controlled clinical trials Efficacy of multicomponent treatment in fibromyalgia syndrome: a meta-analysis of randomized controlled clinical trials Efficacy of multicomponent treatment in fibromyalgia syndrome: a meta-analysis of randomized controlled clinical trials Hauser W, Bernardy K, Arnold B, Offenbacher M, Schiltenwolf M CRD summary The review concluded there was strong evidence (...) that multicomponent treatment had beneficial short-term effects on the key symptoms of fibromyalgia syndrome including pain, fatigue and depressive mood, and of improved self-efficacy and physical fitness post-treatment. The authors' conclusions appeared reasonable, but it should be borne in mind that results of some outcomes were based on a small number of trials. Authors' objectives To evaluate the efficacy of multicomponent treatment of fibromyalgia syndrome. Searching MEDLINE, PsycINFO, Scopus

Full Text available with Trip Pro

2009 DARE.

159. Components of effective randomized controlled trials of hydrotherapy programs for fibromyalgia syndrome: a systematic review

Components of effective randomized controlled trials of hydrotherapy programs for fibromyalgia syndrome: a systematic review Components of effective randomized controlled trials of hydrotherapy programs for fibromyalgia syndrome: a systematic review Components of effective randomized controlled trials of hydrotherapy programs for fibromyalgia syndrome: a systematic review Perraton L, Machotka Z, Kumar S CRD summary This review concluded that exercise appeared to be the most important component (...) of an effective hydrotherapy programme for fibromyalgia syndrome, particularly when considering mental health components. Only trials that reported positive results were included, patient details were not reported and many results were not based on between-group comparisons, so the authors' conclusions should be treated with caution Authors' objectives To summarise the components of hydrotherapy programmes for fibromyalgia syndrome. Searching AMED, MEDLINE, CINAHL, EMBASE, PubMed, SPORTDiscus, Scopus, PEDro

2009 DARE.

160. Efficacy of acupuncture for the treatment of fibromyalgia: systematic review and meta-analysis of randomized trials

Efficacy of acupuncture for the treatment of fibromyalgia: systematic review and meta-analysis of randomized trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.