Latest & greatest articles for folic acid

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Top results for folic acid

41. Mental health literacy, folic acid and vitamin B12, and physical activity for the prevention of depression in older adults: randomised controlled trial (Full text)

Mental health literacy, folic acid and vitamin B12, and physical activity for the prevention of depression in older adults: randomised controlled trial Few randomised controlled trials (RCTs) have examined potential preventive agents in high-risk community populations.To determine whether a mental health literacy intervention, the promotion of physical activity, or folic acid plus vitamin B(12) reduce depression symptoms in community-dwelling older adults with elevated psychological distress.An (...) RCT with a completely crossed 2 x 2 x 2 factorial design: (400 mcg/d folic acid + 100 mcg/d vitamin B(12) v. placebo)x(physical activity v. nutrition promotion control)x(mental health literacy v. pain information control). The initial target sample size was 2000; however, only 909 adults (60-74 years) met the study criteria. Interventions were delivered by mail with telephone calls. The main outcome was depressive symptoms on the Patient Health Questionnaire (PHQ-9) at 6 weeks, 6, 12 and 24 months

2010 EvidenceUpdates PubMed

42. Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial. (Full text)

Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial. Blood homocysteine levels are positively associated with cardiovascular disease, but it is uncertain whether the association is causal.To assess the effects of reducing homocysteine levels with folic acid and vitamin B(12) on vascular and nonvascular outcomes.Double-blind randomized controlled trial of 12,064 survivors (...) of myocardial infarction in secondary care hospitals in the United Kingdom between 1998 and 2008.2 mg folic acid plus 1 mg vitamin B(12) daily vs matching placebo.First major vascular event, defined as major coronary event (coronary death, myocardial infarction, or coronary revascularization), fatal or nonfatal stroke, or noncoronary revascularization.Allocation to the study vitamins reduced homocysteine by a mean of 3.8 micromol/L (28%). During 6.7 years of follow-up, major vascular events occurred in 1537

2010 JAMA PubMed

43. Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: a meta-analysis (Full text)

Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: a meta-analysis Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: a meta-analysis Efficacy of homocysteine-lowering therapy with folic acid in stroke prevention: a meta-analysis Lee M, Hong KS, Chang SC, Saver JL CRD summary The authors concluded that folic acid supplementation was not associated with a major effect in averting stroke. This conclusion reflects the evidence presented (...) and is likely to be reliable, although incomplete reporting of review processes suggests a need for some caution. Authors' objectives To assess the efficacy of folic acid supplementation in the prevention of stroke. Searching MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL) and ClinicalTrials.gov were searched from January 1966 to May 2009. Search terms were reported. No language restrictions were applied. Abstracts of American Heart Association-sponsored meetings were searched from January

2010 DARE. PubMed

44. Meta-analysis of folic acid supplementation trials on risk of cardiovascular disease and risk interaction with baseline homocysteine levels

Meta-analysis of folic acid supplementation trials on risk of cardiovascular disease and risk interaction with baseline homocysteine levels Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

45. Meta-analysis: folic acid in the chemoprevention of colorectal adenomas and colorectal cancer

Meta-analysis: folic acid in the chemoprevention of colorectal adenomas and colorectal cancer Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

46. Folic acid to reduce neonatal mortality from neural tube disorders

Folic acid to reduce neonatal mortality from neural tube disorders Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

47. Management issues for women with epilepsy--focus on pregnancy (an evidence-based review): III. Vitamin K, folic acid, blood levels, and breast-feeding (PubMed)

Management issues for women with epilepsy--focus on pregnancy (an evidence-based review): III. Vitamin K, folic acid, blood levels, and breast-feeding A committee assembled by the American Academy of Neurology (AAN) reassessed the evidence related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid and prenatal vitamin K use and the clinical implications of placental and breast-milk transfer of antiepileptic drugs (AEDs). The committee evaluated (...) the available evidence based on a structured literature review and classification of relevant articles. Preconceptional folic acid supplementation is possibly effective in preventing major congenital malformations in the newborns of WWE taking AEDs. There is inadequate evidence to determine if the newborns of WWE taking AEDs have a substantially increased risk of hemorrhagic complications. Primidone and levetiracetam probably transfer into breast milk in clinically important amounts. Valproate

2009 EvidenceUpdates

48. Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada. (Full text)

Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada. To investigate whether the 1998 government policy for mandatory fortification of flour and pasta products with folate was followed by a reduction in the prevalence of severe congenital heart defects.Time trend analysis.Province of Quebec, Canada.Infants born in 1990-2005 identified with severe congenital heart defects (tetralogy of Fallot, endocardial cushion (...) 2083 infants born with severe congenital heart defects, corresponding to an average birth prevalence of 1.57/1000 births. Time trend analysis showed no change in the birth prevalence of severe birth defects in the nine years before fortification (rate ratio 1.01, 95% confidence interval 0.99 to 1.03), while in the seven years after fortification there was a significant 6% decrease per year (0.94, 0.90 to 0.97).Public health measures to increase folic acid intake were followed by a decrease

2009 BMJ PubMed

49. Folic acid for the prevention of neural tube defects: U.S. Preventive Services Task Force recommendation statement. (PubMed)

Folic acid for the prevention of neural tube defects: U.S. Preventive Services Task Force recommendation statement. In 1996, the U.S. Preventive Services Task Force (USPSTF) recommended that all women planning or capable of pregnancy take a multivitamin supplement containing folic acid for the prevention of neural tube defects. This recommendation is an update of the 1996 USPSTF recommendation.The USPSTF reviewed the evidence on folic acid supplementation in women of childbearing age published (...) since the 1996 USPSTF recommendation. The USPSTF did not review the evidence on folic acid food fortification, counseling to increase dietary intake, or screening for neural tube defects.The USPSTF recommends that all women planning or capable of pregnancy take a daily supplement containing 0.4 to 0.8 mg (400 to 800 microg) of folic acid. (Grade A recommendation).

2009 Annals of Internal Medicine

50. Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force. (PubMed)

Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force. Neural tube defects (NTDs) are among the most common birth defects in the United States. In 1996, the U.S. Preventive Services Task Force (USPSTF) recommended that all women planning a pregnancy or capable of conception take a supplement containing folic acid to reduce the risk for NTDs.To search for new evidence published since 1996 on the benefits (...) and harms of folic acid supplementation for women of childbearing age to prevent neural tube defects in offspring, to inform an updated USPSTF recommendation.MEDLINE and Cochrane Central Register of Controlled Trials searches from January 1995 through December 2008, recent systematic reviews, reference lists of retrieved articles, and expert suggestions.English-language randomized, controlled trials; cohort studies; case-control studies; systematic reviews; and meta-analyses were selected

2009 Annals of Internal Medicine

51. Practice Parameter update: Managment issues for women with epilepsy - Focus on pregnancy: Vitamin K, folic acid, blood levels, and breastfeeding

Practice Parameter update: Managment issues for women with epilepsy - Focus on pregnancy: Vitamin K, folic acid, blood levels, and breastfeeding DOI 10.1212/WNL.0b013e3181a6b325 2009;73;142-149 Published Online before print April 27, 2009 Neurology C. L. Harden, P. B. Pennell, B. S. Koppel, et al. of Neurology and American Epilepsy Society Technology Assessment Subcommittee of the American Academy the Quality Standards Subcommittee and Therapeutics and Vitamin K, folic acid, blood levels (...) , MD J. Hopp, MD T.Y. Ting, MD W.A. Hauser, MD D.Thurman,MD,MPH P.W.Kaplan,MB,FRCP J.N. Robinson, MD J.A. French, MD S. Wiebe, MD A.N. Wilner, MD B. Vazquez, MD L. Holmes, MD A. Krumholz, MD R. Finnell, PhD P.O. Shafer, RN, MN C. Le Guen ABSTRACT Objective:To reassess the evidence for management issues related to the care of women with epilepsy (WWE) during pregnancy, including preconceptional folic acid use, prenatal vitamin K use, risk of hemorrhagic disease of the newborn, clinical implications

2009 American Epilepsy Society

52. Management issues for women with epilepsy-focus on pregnancy: vitamin k, folic acid, blood levels, and breastfeeding

Management issues for women with epilepsy-focus on pregnancy: vitamin k, folic acid, blood levels, and breastfeeding Practice Parameter update: Management issues for women with epilepsy—Focus on pregnancy (an evidence-based review): Vitamin K, folic acid, blood levels, and breastfeeding | Neurology Advertisement Search for this keyword Main menu User menu Search Search for this keyword The most widely read and highly cited peer-reviewed neurology journal Share July 14, 2009 ; 73 (2) Special (...) Article Practice Parameter update: Management issues for women with epilepsy—Focus on pregnancy (an evidence-based review): Vitamin K, folic acid, blood levels, and breastfeeding Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society C. L. Harden , P. B. Pennell , B. S. Koppel , C. A. Hovinga , B. Gidal , K. J. Meador , J. Hopp , T. Y. Ting , W. A. Hauser , D. Thurman , P. W. Kaplan , J. N

2009 American Academy of Neurology

53. Cancer incidence and mortality after treatment with folic acid and vitamin B12. (Full text)

Cancer incidence and mortality after treatment with folic acid and vitamin B12. Recently, concern has been raised about the safety of folic acid, particularly in relation to cancer risk.To evaluate effects of treatment with B vitamins on cancer outcomes and all-cause mortality in 2 randomized controlled trials.Combined analysis and extended follow-up of participants from 2 randomized, double-blind, placebo-controlled clinical trials (Norwegian Vitamin Trial and Western Norway B Vitamin (...) Intervention Trial). A total of 6837 patients with ischemic heart disease were treated with B vitamins or placebo between 1998 and 2005, and were followed up through December 31, 2007.Oral treatment with folic acid (0.8 mg/d) plus vitamin B(12) (0.4 mg/d) and vitamin B(6) (40 mg/d) (n = 1708); folic acid (0.8 mg/d) plus vitamin B(12) (0.4 mg/d) (n = 1703); vitamin B(6) alone (40 mg/d) (n = 1705); or placebo (n = 1721).Cancer incidence, cancer mortality, and all-cause mortality.During study treatment

2009 JAMA PubMed

54. Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics and Technology Asse (Full text)

Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics and Technology Asse Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics (...) and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society Harden CL, Pennell PB, Koppel BS, Hovinga CA, Gidal B, Meador KJ

2009 DARE. PubMed

55. Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force

Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force Wolff T, Witkop CT, Miller T, Syed SB Record Status This is a bibliographic (...) record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Wolff T, Witkop CT, Miller T, Syed SB. Folic acid supplementation for the prevention of neural tube defects: an update of the evidence for the U.S. Preventive Services Task Force. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Synthesis No 70. 2009 Authors' objectives To update the evidence on folic acid

2009 Health Technology Assessment (HTA) Database.

56. Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review

Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review Prey S, Paul C CRD summary This review assessed the efficacy of folic acid (...) supplementation in patients receiving methotrexate for inflammatory diseases, concluding that was an effective measure to reduce hepatic side-effects associated with methotrexate treatment. However, given the small number of included studies of uncertain quality, the authors' conclusions should be interpreted with caution. Authors' objectives To assess the efficacy of folic acid supplementation in patients receiving methotrexate treatment for inflammatory diseases. Searching MEDLINE, EMBASE, Cochrane Skin

2009 DARE.

57. High-dose folic acid supplementation effects on endothelial function and blood pressure in hypertensive patients: a meta-analysis of randomized controlled clinical trials

High-dose folic acid supplementation effects on endothelial function and blood pressure in hypertensive patients: a meta-analysis of randomized controlled clinical trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

58. Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. (PubMed)

Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. Folate deficiency can result in congenital neural tube defects and megaloblastic anaemia. Low folate levels may be due to insufficient dietary intake or inefficient absorption, but impaired metabolic utilization also occurs.Because B12 deficiency can produce a similar anaemia to folate deficiency, there is a risk that folate supplementation can delay the diagnosis of B12 deficiency (...) , which can cause irreversible neurological damage. Folic acid supplements may sometimes therefore include vitamin B12 supplements with simultaneous administration of vitamin B12.Lesser degrees of folate inadequacy are associated with high blood levels of the amino acid homocysteine which has been linked with the risk of arterial disease, dementia and Alzheimer's disease. There is therefore interest in whether dietary supplementation can improve cognitive function in the elderly.However, any apparent

2008 Cochrane

59. Daily folic acid supplementation for 3 years reduced age related hearing loss

Daily folic acid supplementation for 3 years reduced age related hearing loss Daily folic acid supplementation for 3 years reduced age related hearing loss | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Daily folic acid supplementation for 3 years reduced age related hearing loss Article Text Treatment Daily folic acid supplementation for 3 years reduced age related hearing loss Statistics from Altmetric.com Request Permissions If you

2008 Evidence-Based Nursing

60. Daily folic acid supplementation for 3 years improved cognitive function in older persons

Daily folic acid supplementation for 3 years improved cognitive function in older persons Daily folic acid supplementation for 3 years improved cognitive function in older persons | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Daily folic acid supplementation for 3 years improved cognitive function in older persons Article Text Therapeutics Daily folic acid supplementation for 3 years improved cognitive function in older persons Statistics

2008 Evidence-Based Medicine (Requires free registration)