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Latest & greatest articles for glimepiride
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Duetact (pioglitazone HCl + glimepiride) Drug Approval Package: Duetact (pioglitazone HCl + glimepiride) NDA #021925 Drug Approval Package U.S. Food & Drug Administration Search FDA Drug Approval Package - Duetact (pioglitazone HCl + glimepiride) Company: Takeda Global Research & Development Center, Inc. Application No.: 021925 Approval Date: 07/28/2006 (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) Date created: September 4, 2008 Note: Documents in PDF format require the . - - Links on this page
Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: a randomized trial. Carotid artery intima-media thickness (CIMT) is a marker of coronary atherosclerosis and independently predicts cardiovascular events, which are increased in type 2 diabetes mellitus (DM). While studies of relatively short duration have suggested that thiazolidinediones such as pioglitazone might reduce progression of CIMT in persons with diabetes, the results of longer (...) studies have been less clear.To evaluate the effect of pioglitazone vs glimepiride on changes in CIMT of the common carotid artery in patients with type 2 DM.Randomized, double-blind, comparator-controlled, multicenter trial in patients with type 2 DM conducted at 28 clinical sites in the multiracial/ethnic Chicago metropolitan area between October 2003 and May 2006. The treatment period was 72 weeks (1-week follow-up). CIMT images were captured by a single ultrasonographer at 1 center and read
Glimepiride: role of a new sulfonylurea in the treatment of type 2 diabetes mellitus Glimepiride: role of a new sulfonylurea in the treatment of type 2 diabetes mellitus Glimepiride: role of a new sulfonylurea in the treatment of type 2 diabetes mellitus Campbell R K Authors' objectives To assess the efficacy and safety of glimepiride with and without insulin in the treatment of type 2 diabetes mellitus. Searching A MEDLINE database search (January 1985 to April 1997) was performed for English (...) language studies, including reviews and abstracts. The author also contacted a manufacturer of glimepiride (Hoechst Marion Roussel) for unpublished study data. Study selection Study designs of evaluations included in the review Large (but actual size unspecified) double-blind, randomised controlled trials (RCTs) were included in the review. Included trials had to be published as an individual study, as part of a review, or pending publication. Relatively small, nonrandomised, noncomparative, open-label