Latest & greatest articles for irritable bowel syndrome

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Top results for irritable bowel syndrome

44. Herbal Medicines for the Management of Irritable Bowel Syndrome: A Systematic Review. (PubMed)

Herbal Medicines for the Management of Irritable Bowel Syndrome: A Systematic Review. Irritable Bowel Syndrome (IBS) is a chronic digestive disorder, which is characterized by abdominal pain, bloating, diarrhea and constipation periods. The etiology is unknown. Based on the different mechanisms in the etiology, treatment focuses on controlling symptoms. Due to the longtime of syndrome, inadequacy of current treatments, financial burden for patients and pharmacologic effects, several patients

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2016 Electronic physician

45. Truberzi (eluxadoline) - for the treatment of adults who have irritable bowel syndrome with diarrhoea

Truberzi (eluxadoline) - for the treatment of adults who have irritable bowel syndrome with diarrhoea 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5555 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2016. Reproduction is authorised provided the source is acknowledged. 21 July 2016 EMA/549473/2016 Committee for Medicinal Products for Human Use (...) index BSS Bristol Stool Scale CHMP Committee for Medicinal Products for Human Use Cmax maximum observed plasma concentration CNS central nervous system CSR clinical study report EMA European Medicines Agency EU European Union FDA US Food and Drug Administration GERD gastroesophageal reflux disease GI gastrointestinal IBS irritable bowel syndrome IBS-d diarrhea-predominant irritable bowel syndrome IBS-m irritable bowel syndrome, where a mixture of constipation and diarrhea is predominant IBS-QoL

2016 European Medicines Agency - EPARs

46. Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women (PubMed)

Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women Previous studies have indicated that serotonin-3-receptor antagonists might have a sex-specific effect in patients with irritable bowel syndrome with diarrhea (IBS-D). Alosetron has been approved for the treatment of only women, and ramosetron has been approved for the treatment for only men. We performed a randomized, placebo-controlled, phase 3 study to determine whether ramosetron

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2016 EvidenceUpdates

47. Underlying molecular and cellular mechanisms in childhood irritable bowel syndrome (PubMed)

Underlying molecular and cellular mechanisms in childhood irritable bowel syndrome Irritable bowel syndrome (IBS) affects a large number of children throughout the world. The symptom expression of IBS is heterogeneous, and several factors which may be interrelated within the IBS biopsychosocial model play a role. These factors include visceral hyperalgesia, intestinal permeability, gut microbiota, psychosocial distress, gut inflammation, bile acids, food intolerance, colonic bacterial

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2016 Molecular and cellular pediatrics

48. Genetics of irritable bowel syndrome (PubMed)

Genetics of irritable bowel syndrome Irritable bowel syndrome (IBS) is a common condition with a complex and largely unknown etiology. There is no cure, and treatment options are mainly directed to the amelioration of symptoms. IBS causes reduced quality of life and poses considerable repercussions on health and socioeconomic systems. There is a heritable component in IBS, and genetic research is a valuable tool for the identification of causative pathways, which will provide important insight

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2016 Molecular and cellular pediatrics

49. Eluxadoline for Irritable Bowel Syndrome with Diarrhea. (PubMed)

Eluxadoline for Irritable Bowel Syndrome with Diarrhea. Background Effective and safe treatments are needed for patients who have irritable bowel syndrome (IBS) with diarrhea. We conducted two phase 3 trials to assess the efficacy and safety of eluxadoline, a new oral agent with mixed opioid effects (μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist), in patients with IBS with diarrhea. Methods We randomly assigned 2427 adults who had IBS with diarrhea to eluxadoline (at a dose

2016 NEJM

50. Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome as Well as Traditional Dietary Advice: A Randomized Controlled Trial (PubMed)

Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome as Well as Traditional Dietary Advice: A Randomized Controlled Trial A diet with reduced content of fermentable short-chain carbohydrates (fermentable oligo-, di-, monosaccharides, and polyols [FODMAPs]) has been reported to be effective in the treatment of patients with irritable bowel syndrome (IBS). However, there is no evidence of its superiority to traditional dietary advice for these patients. We compared the effects

2016 EvidenceUpdates

51. Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines

Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines | CADTH.ca Find the information you need Trimebutine Maleate and Pinaverium Bromide for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines Trimebutine Maleate and Pinaverium Bromide (...) for Irritable Bowel Syndrome: A Review of the Clinical Effectiveness, Safety and Guidelines Published on: November 30, 2015 Project Number: RC0721-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness and safety of trimebutine maleate for the treatment of patients with irritable bowel syndrome? What is the clinical effectiveness and safety of pinaverium bromide for the treatment of patients with irritable bowel

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

52. Epidemiology of irritable bowel syndrome in the former communist countries from Eastern Europe: a systematic review. (PubMed)

Epidemiology of irritable bowel syndrome in the former communist countries from Eastern Europe: a systematic review. The irritable bowel syndrome (IBS) is a functional gastrointestinal disorder frequently encountered in clinical practice in Eastern Europe. Epidemiological data are diverging on this condition. Our objective was to assess the prevalence of IBS in the former communist countries from Eastern Europe (EE).We performed a systematic review study using data from PubMed. Many languages (...) , some having only local spreading, are spoken in EE, so we decided to look only for papers indexed in PubMed, which have at least an English summary or title. We searched PubMed using the following keywords: irritable bowel syndrome, functional digestive disorders, prevalence, EE. Only relevant studies were selected for analysis.From more than 4000 papers retrieved by this search, we identified a few papers appropriate to this survey. The spectrum of prevalence values is wide in IBS. Prevalence

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2015 Clujul medical (1957)

53. Probiotic for irritable bowel syndrome in pediatric patients: a randomized controlled clinical trial. (PubMed)

Probiotic for irritable bowel syndrome in pediatric patients: a randomized controlled clinical trial. Irritable bowel syndrome (IBS) is a common gastrointestinal disorder in children. Recently, probiotics have been suggested as a treatment option for gastrointestinal disorders. The most effective species and the most appropriate doses are still unknown.The aim of this study was to assess the effects of Lactobacillus GG (LGG) for treating IBS in pediatric patients.In a controlled, double blind (...) one, two, three, and four weeks of treatment, as indicated by P-values of 0.01, 0.00, 0.00, and 0.00, respectively. Also, there was significant improvement in the functional scale after two weeks of treatment (P-value ≤ 0.00).Lactobacillus GG at a concentration of 1×10(10) cfu/ml for a period of four weeks can lessen the severity of the patients' pain and improve the functional scale in patients with irritable bowel syndrome. Probiotics can have therapeutic effects for IBS patients.

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2015 Electronic physician

54. Linaclotide (Constella) in the symptomatic management of irritable bowel syndrome with constipation, The indication was granted...so what?

Linaclotide (Constella) in the symptomatic management of irritable bowel syndrome with constipation, The indication was granted...so what? 2015. DAR No 4: Linaclotide. Constella® in the symptomatic management of irritable bowel syndrome with constipation - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : DAR No 4: Linaclotide. Constella® in the symptomatic management of irritable bowel syndrome with constipation DAR No 4: Linaclotide. Constella (...) ® in the symptomatic management of irritable bowel syndrome with constipation Content tools Share it The indication was granted...so what? Although authorized for irritable bowel syndrome with constipation it offers only symptomatic relief. In the best of cases, one in five patients can benefit from treatment. On the other hand, one in five patients can suffer from diarrhea as a secondary effect which can last for more than 28 days in half the cases. There are no available studies evaluating

2015 Drug and Therapeutics Bulletin of Navarre (Spain)

55. Irritable bowel syndrome: new and emerging treatments. (PubMed)

Irritable bowel syndrome: new and emerging treatments. Irritable bowel syndrome is one of the most common gastrointestinal disorders in developed nations. It is characterized by abdominal pain, altered bowel habits, and bloating. Several non-pharmacological and pharmacological agents, which target the peripheral gastrointestinal system and central nervous system, are used to treat the syndrome. The individual and societal impact of investigating and managing the syndrome is substantial (...) , and despite newer treatments, many patients have unmet needs. Intense research at many international sites has improved the understanding of pathophysiology of the syndrome, but developing treatments that are effective, safe, and that have tolerable side effects remains a challenge. This review briefly summarizes the currently available treatments for irritable bowel syndrome then focuses on newer non-pharmacological and pharmacological therapies and recent evidence for older treatments. Recent guidelines

2015 BMJ

56. Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): a multicentre, parallel-group, randomised placebo-controlled trial

Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): a multicentre, parallel-group, randomised placebo-controlled trial Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): a multicentre, parallel-group, randomised placebo-controlled trial Journals Library An error has occurred in processing the XML document An error occurred retrieving content to display, please try

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2015 NIHR HTA programme

57. An antiemetic for irritable bowel syndrome?

An antiemetic for irritable bowel syndrome? An antiemetic for irritable bowel syndrome? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics An antiemetic for irritable bowel syndrome? View/ Open Date 2014-10 Format Metadata Abstract An antiemetic for irritable bowel syndrome? A drug used for cancer patients may provide (...) some relief to patients with IBS. Practice changer: Consider prescribing ondansetron up to 24 mg/d for patients who have irritable bowel syndrome with diarrhea (IBS-D). URI Part of Citation Journal of Family Practice, 63(10) 2014: 600-602. Rights OpenAccess. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License. Collections hosted by hosted by

2015 PURLS

58. Qualitative study?other: Uncovering male and female experiences of irritable bowel syndrome

Qualitative study?other: Uncovering male and female experiences of irritable bowel syndrome Uncovering male and female experiences of irritable bowel syndrome | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Uncovering male and female experiences of irritable bowel syndrome Article Text Adult nursing Qualitative study—other Uncovering male and female experiences of irritable bowel syndrome Graeme D Smith Statistics from Altmetric.com

2015 Evidence-Based Nursing

59. Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS) World Gastroenterology Organisation Global Guidelines Irritable Bowel Syndrome: a Global Perspective Update September 2015 Review team Eamonn M.M. Quigley USA (Chair) Michael Fried Switzerland Kok-Ann Gwee Singapore Igor Khalif Russia Pali Hungin United Kingdom Greger Lindberg Sweden Zaigham Abbas Pakistan Luis Bustos Fernandez Argentina Shobna J. Bhatia India Max Schmulson Mexico Carolina Olano Uruguay Anton Le Mair The Netherlands WGO Global Guidelines IBS 2 (...) Diagnostic criteria (Rome III) 12 4.2 Additional tests or investigatations 13 4.3 Differential diagnosis 13 4.4 Comorbidity with other diseases 17 5 Management of IBS 17 5.1 Introduction 17 5.2 Diet 19 5.3 Drug therapy 20 5.4 Psychological and other treatments 23 5.5 Prognosis 24 5.6 Follow-up 25 6 Appendix: useful resources 25 References 26 Figures Fig. 1 Algorithm for diagnosing irritable bowel syndrome (IBS) 11 Fig. 2 Management of patients with symptoms of irritable bowel syndrome 18 Tables Table 1

2015 World Gastroenterology Organisation

60. Viberzi (eluxadoline) - To treat irritable bowel syndrome with diarrhea (IBS-D) in adult men and women

Viberzi (eluxadoline) - To treat irritable bowel syndrome with diarrhea (IBS-D) in adult men and women Viberzi (eluxadoline) Tablets U.S. Department of Health and Human Services Search FDA Submit search Viberzi (eluxadoline) Tablets Viberzi (eluxadoline) Tablet Company: Furiex Pharmaceuticals, Inc. Application No.: 206940 Approval Date: 05/27/2015 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. (PDF) (PDF) (PDF) (PDF) (PDF) (PDF

2015 FDA - Drug Approval Package