Latest & greatest articles for low back pain

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Top results for low back pain

61. Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial

Efficacy of Low-Dose Amitriptyline for Chronic Low Back Pain: A Randomized Clinical Trial Antidepressants at low dose are commonly prescribed for the management of chronic low back pain and their use is recommended in international clinical guidelines. However, there is no evidence for their efficacy.To examine the efficacy of a low-dose antidepressant compared with an active comparator in reducing pain, disability, and work absence and hindrance in individuals with chronic low back pain.A (...) double-blind, randomized clinical trial with a 6-month follow-up of adults with chronic, nonspecific, low back pain who were recruited through hospital/medical clinics and advertising was carried out.Low-dose amitriptyline (25 mg/d) or an active comparator (benztropine mesylate, 1 mg/d) for 6 months.The primary outcome was pain intensity measured at 3 and 6 months using the visual analog scale and Descriptor Differential Scale. Secondary outcomes included disability assessed using the Roland Morris

2018 EvidenceUpdates

62. The Effect of Combination Pharmacotherapy on Low Back Pain: A Meta-analysis

The Effect of Combination Pharmacotherapy on Low Back Pain: A Meta-analysis To evaluate the difference between combination pharmacotherapy and monotherapy on low back pain (LBP).We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials databases up to March 14, 2017. Two authors independently extracted the data and assessed the validity of included trials.Twelve randomized controlled trials comparing the effect of LBP combination pharmacotherapy to monotherapy or placebo (...) were included. In chronic LBP, combination pharmacotherapy was more effective than placebo in pain relief (P<0.001; standardized mean difference [SMD], -0.50; 95% confidence interval [CI], -0.70 to -0.29; I²=0%) and function improvement (P<0.001; SMD, -0.27; 95% CI, -0.41 to -0.13; I²=0%) and showed improved pain relief compared with monotherapy (P<0.001; SMD, -0.84; 95% CI, -1.12 to -0.56; I²=0%). Combination pharmacotherapy did not outperform monotherapy pain relief and function improvement

2018 EvidenceUpdates

63. The association of high-intensity zones on MRI and low back pain: a systematic review (Full text)

The association of high-intensity zones on MRI and low back pain: a systematic review Magnetic resonance imaging (MRI) of the lumbar spine is commonly used to identify the source of low back pain (LBP); however, its use has been questionable. Throughout the years, numerous lumbar phenotypes (e.g., endplate abnormalities, Modic changes, black disc) have been studied as possible pain generators. High-intensity zones (HIZs) are of particular interest as they may represent annular tears. However (...) , for over three decades, there has been heated debate as to whether these imaging biomarkers are synonymous with LBP. Therefore, the following study addressed a systematic review of the reported literature addressing the relationship of HIZs and LBP.A systematic review was conducted via MEDLINE, SCOPUS, Cochrane, PubMed, PubMed Central, EMBASE via Ovid, and Web of Science with the following search terms: "HIZ," "high intensity zone," or "high intensity zones" and "low back pain," "pain," "lumbago

2018 Scoliosis and spinal disorders PubMed

64. Effectiveness and Downstream Healthcare Utilization for Patients That Received Early Physical Therapy Versus Usual Care for Low Back Pain: A Randomized Clinical Trial

Effectiveness and Downstream Healthcare Utilization for Patients That Received Early Physical Therapy Versus Usual Care for Low Back Pain: A Randomized Clinical Trial Randomized controlled trial.The aim of this study was to compare early physical therapy versus usual care in patients with low back pain.Early physical therapy (PT) has been associated with reduced downstream healthcare utilization in retrospective studies, but not investigated prospectively in the military health system.Military (...) significantly between groups (UC $5037; 95 CI $4171-$6082 and PT $5299; 95 CI $4367-$6431). The portion of total mean healthcare costs related to low back pain was lower for UC ($1096; 95% CI $855-$1405) compared to PT ($2016, 95% CI $1570-$2590).There was no difference between usual care and early PT after 1 year. PT provided greater improvement in disability after 4 weeks. As both groups improved, the impact of the education may have been underestimated. Patients in the PT group utilized greater back-pain

2018 EvidenceUpdates

65. Osteopathic Manipulative Treatment Including Specific Diaphragm Techniques Improves Pain and Disability in Chronic Nonspecific Low Back Pain: A Randomized Trial

Osteopathic Manipulative Treatment Including Specific Diaphragm Techniques Improves Pain and Disability in Chronic Nonspecific Low Back Pain: A Randomized Trial To investigate the effects of an osteopathic manipulative treatment (OMT), which includes a diaphragm intervention compared to the same OMT with a sham diaphragm intervention in chronic nonspecific low back pain (NS-CLBP).Parallel group randomized controlled trial.Private and institutional health centers.Participants (N=66) (18-60y (...) ) with a diagnosis of NS-CLBP lasting at least 3 months.Participants were randomized to receive either an OMT protocol including specific diaphragm techniques (n=33) or the same OMT protocol with a sham diaphragm intervention (n=33), conducted in 5 sessions provided during 4 weeks.The primary outcomes were pain (evaluated with the Short-Form McGill Pain Questionnaire [SF-MPQ] and the visual analog scale [VAS]) and disability (assessed with the Roland-Morris Questionnaire [RMQ] and the Oswestry Disability Index

2018 EvidenceUpdates

66. Cognitive behavioural therapy may help people with persistent low back pain

Cognitive behavioural therapy may help people with persistent low back pain Cognitive behavioural therapy may help people with persistent low back pain Discover Portal Discover Portal Cognitive behavioural therapy may help people with persistent low back pain Published on 14 October 2015 doi: This NIHR-funded systematic review aimed to assess the effectiveness of talking therapies in improving outcomes for people with non-specific low back pain. It found that cognitive behavioural therapies (...) people experiencing lower back pain and the risk of ongoing problems for those with recent symptoms. However, the review included many different interventions, many of which were not properly described, which limit the uptake and implementation of findings in practice. It is likely that a substantial increase in NHS capacity would be needed to deliver cognitive behavioural therapies for the many people with persistent low back pain. This may be important though, as the provision of programmes

2018 NIHR Dissemination Centre

67. Low back pain: no corticosteroids

Low back pain: no corticosteroids Prescrire IN ENGLISH - Spotlight ''Low back pain: no corticosteroids '', 1 September 2018 {1} {1} {1} | | > > > Low back pain: no corticosteroids Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Low back pain: no corticosteroids There is no evidence that systemic corticosteroids have any efficacy on low back pain (...) , beyond a placebo effect. Furthermore, they expose patients to numerous adverse effects. Low back pain is common in adults. It is sometimes accompanied by pain spreading into the lower limbs (radiculalgia). In most cases, it improves spontaneously, within a few days or weeks. When low back pain persists for more than three months, it is termed chronic. In most cases, there is no identifiable cause. Several trials have compared systemic corticosteroid therapy with a placebo. Their results converge

2018 Prescrire

68. Is oral orphenadrine beneficial for acute low back pain?

Is oral orphenadrine beneficial for acute low back pain? Is oral orphenadrine beneficial for acute low back pain? – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2018\/08\/mo_2018-08_p46-7_cover.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Aug 21 2018 Is oral orphenadrine beneficial for acute (...) low back pain? By in , Journal reference: Friedman BW, Cisewski D, Irizarry E, et al. A Randomized, Double-Blind, Placebo-Controlled Trial of Naproxen With or Without Orphenadrine or Methocarbamol for Acute Low Back Pain. Ann Emerg Med 2018 Mar;71(3):348-56 e5 Link: Published: March 2018 Evidence cookie says… Orphenadrine provides no benefit when used in addition to naproxen for acute low back pain the point estimate is close to zero, with the imprecision of the estimate well within the minimal

2018 Morsels of Evidence

69. Is oral orphenadrine beneficial for acute low back pain?

Is oral orphenadrine beneficial for acute low back pain? Is oral orphenadrine beneficial for acute low back pain? – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Share this: Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2018\/08\/mo_2018-08_p46-7_cover.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Aug 21 2018 Is oral orphenadrine (...) beneficial for acute low back pain? By in , 21 August 2018 Journal reference: Friedman BW, Cisewski D, Irizarry E, et al. A Randomized, Double-Blind, Placebo-Controlled Trial of Naproxen With or Without Orphenadrine or Methocarbamol for Acute Low Back Pain. Ann Emerg Med 2018 Mar;71(3):348-56 e5 Link: Published: March 2018 Evidence cookie says… Orphenadrine provides no benefit when used in addition to naproxen for acute low back pain the point estimate is close to zero, with the imprecision

2018 Morsels of Evidence

70. Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis (Full text)

Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis The use of anticonvulsants (e.g., gabapentin, pregabalin) to treat low back pain has increased substantially in recent years despite limited supporting evidence. We aimed to determine the efficacy and tolerability of anticonvulsants in the treatment of low back pain and lumbar radicular pain compared with placebo.A search was conducted in 5 databases for studies comparing (...) an anticonvulsant to placebo in patients with nonspecific low back pain, sciatica or neurogenic claudication of any duration. The outcomes were self-reported pain, disability and adverse events. Risk of bias was assessed using the Physiotherapy Evidence Database (PEDro) scale, and quality of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE). Data were pooled and treatment effects were quantified using mean differences for continuous and risk ratios

2018 EvidenceUpdates PubMed

71. The effects of transcranial direct current stimulation (tDCS) combined with group exercise treatment in subjects with chronic low back pain: a pilot randomized control trial

The effects of transcranial direct current stimulation (tDCS) combined with group exercise treatment in subjects with chronic low back pain: a pilot randomized control trial To test the efficacy of transcranial direct current stimulation (tDCS) in addition to group exercise on non-specific chronic low back pain.Double-blinded randomized control trial.Patients with non-specific chronic low back pain.A total of 35 subjects were recruited and allocated to real- or sham-tDCS followed by a group (...) exercise protocol. Each patient underwent five sessions of brain stimulation followed by 10 sessions of group exercise. Subjects were evaluated before and after tDCS, after group exercise and one month after the combined treatment. Outcome measures were Visual Analog Scale for pain intensity, Roland Morris Disability Questionnaire, EuroQuol-5 Dimension and Patient Health Questionnaire-9.Significant between-group difference in pain intensity (-27.7 ± 30.4 mm in real-tDCS group compared to -2.2 ± 30.1 mm

2018 EvidenceUpdates

72. Neurophysiological Pain Education for Patients With Chronic Low Back Pain: A Systematic Review and Meta-Analysis (Full text)

Neurophysiological Pain Education for Patients With Chronic Low Back Pain: A Systematic Review and Meta-Analysis To evaluate the effect of neurophysiological pain education (NPE) for patients with chronic low back pain (CLBP).A systematic search was performed in 6 electronic databases. Eligible randomized-controlled trials were those with at least 50 % of patients with CLBP and in which NPE was compared with no intervention or usual care. Methodological quality was assessed independently by 2 (...) of the authors using the Cochrane Collaboration Risk of Bias Tool. The effect of NPE was summarized in a random effect meta-analysis for pain, disability, and behavioral attitudes. Effect was estimated as weighted mean difference (WMD) if outcomes were on the same scale or as standardized mean difference (SMD). The overall quality of evidence was evaluated according to GRADE guidelines.Seven randomized-controlled trial studies (6 low and 1 high quality) were included. Statistically significant differences

2018 EvidenceUpdates PubMed

73. Low back pain

Low back pain Top results for low back pain - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2 (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for low back pain The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

74. Transaxial interbody lumbosacral fusion for severe chronic low back pain

Transaxial interbody lumbosacral fusion for severe chronic low back pain T T r ransaxial interbody lumbosacr ansaxial interbody lumbosacral fusion for al fusion for se sev vere chronic low back pain ere chronic low back pain Interventional procedures guidance Published: 25 July 2018 nice.org.uk/guidance/ipg620 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement (...) (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 1 of 41 1 Recommendations Recommendations 1.1 Evidence on the safety of transaxial interbody lumbosacral fusion for severe chronic low back pain shows that there are serious but well-recognised complications. Evidence on efficacy is adequate in quality and quantity. Therefore, this procedure may be used provided that standard arrangements are in place for clinical governance, consent and audit. 1.2 This procedure should only

2018 National Institute for Health and Clinical Excellence - Interventional Procedures

75. Effectiveness of mobilization with movement (Mulligan concept techniques) on low back pain: a systematic review

Effectiveness of mobilization with movement (Mulligan concept techniques) on low back pain: a systematic review To evaluate evidence on the effectiveness of Mulligan techniques on low back pain.PubMed/Medline, Scopus, Ovid, CINAHL, Embase, PEDro, Google Scholar, and Cochrane Library were searched from inception to 31 March 2018 for randomized clinical trials reporting outcomes of pain or disability in adult patients (⩾18 years) with low back pain.Two authors screened the results and extracted (...) can decrease pain and disability and increase range of motion in patients with low back pain; however, the strength of conclusion for pain and disability was moderate. Furthermore, inconclusive results were observed for the effectiveness of Mulligan techniques on movement speed. In this review, eight studies were categorized as low risk of bias, while 12 studies had high risk of bias. Level of evidence analysis revealed that 17 studies were classified as level of evidence B, while three studies

2018 EvidenceUpdates

76. Hypnosis Enhances the Effects of Pain Education in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial

Hypnosis Enhances the Effects of Pain Education in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial The potential benefits of combining pain education (PE) with clinical hypnosis (CH) has not yet been investigated in individuals with chronic pain. A total of 100 patients with chronic nonspecific low back pain were randomized to receive either: 1) PE alone, or 2) PE with CH. Outcomes were collected by a blinded assessor at 2 weeks and 3 months after randomization (...) showing that additional use of hypnosis with PE results in improved outcomes over PE alone in patients with chronic nonspecific low back pain.This study provides evidence supporting the efficacy of another treatment option for teaching patients to self-manage chronic low back pain that has a relatively low cost and that can be offered in groups.Copyright © 2018 The American Pain Society. Published by Elsevier Inc. All rights reserved.

2018 EvidenceUpdates

77. Effect of Low Back Pain Risk-Stratification Strategy on Patient Outcomes and Care Processes: the MATCH Randomized Trial in Primary Care

Effect of Low Back Pain Risk-Stratification Strategy on Patient Outcomes and Care Processes: the MATCH Randomized Trial in Primary Care The STarT Back strategy for categorizing and treating patients with low back pain (LBP) improved patients' function while reducing costs in England.This trial evaluated the effect of implementing an adaptation of this approach in a US setting.The Matching Appropriate Treatments to Consumer Healthcare needs (MATCH) trial was a pragmatic cluster randomized trial (...) Tool) to categorize patients' risk of persistent disabling pain. Primary care clinicians in the intervention clinics attended six didactic sessions to improve their understanding LBP management and received in-person training in the use of the tool that had been incorporated into the electronic health record (EHR). Physical therapists received 5 days of intensive training. Control clinics received no training.Primary outcomes were back-related physical function and pain severity. Intervention

2018 EvidenceUpdates

78. Spinal manipulation and exercise for low back pain in adolescents: a randomized trial

Spinal manipulation and exercise for low back pain in adolescents: a randomized trial Low back pain (LBP) is common in adolescence, but there is a paucity of high-quality research to inform care. We conducted a multicenter randomized trial comparing 12 weeks of spinal manipulative therapy (SMT) combined with exercise therapy (ET) to ET alone. Participants were 185 adolescents aged 12 to 18 years with chronic LBP. The primary outcome was LBP severity at 12, 26, and 52 weeks. Secondary outcomes

2018 EvidenceUpdates

79. The effectiveness of 12 weeks of Pilates intervention on disability, pain and kinesiophobia in patients with chronic low back pain: a randomized controlled trial

The effectiveness of 12 weeks of Pilates intervention on disability, pain and kinesiophobia in patients with chronic low back pain: a randomized controlled trial To assess the effectiveness of 12 weeks of Pilates practice on disability, pain and kinesiophobia in patients with chronic non-specific low back pain.This is a randomized controlled trial.This study was conducted in the university laboratory.A total of 64 participants with chronic non-specific low back pain were included.Participants (...) with Visual Analogue Scale scores of 2.40 (0.26) ( P < 0.001).Pilates intervention in patients with chronic non-specific low back pain is effective in the management of disability, pain and kinesiophobia.

2018 EvidenceUpdates

80. Low back pain

Low back pain Evidence Maps - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4 (...) . Also read , explaining issues with the system. NOTE : Chrome is the best browser to use! To get started, type a condition/disease into the search box above. Here are some examples to get you started: Building Evidence Map X Axis Alphabetically Risk of bias No. Articles Sample Size Risk of bias any low Minimum sample size Apply Follow us: © 2019 Trip Database Ltd. company number 04316414. Trip is proud to be made in the UK.

2018 Trip Evidence Maps