Latest & greatest articles for magnesium

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Top results for magnesium

1. Magnesium for treating sickle cell disease. (PubMed)

Magnesium for treating sickle cell disease. Sickle cell disease is an autosomal recessive inherited haemoglobinopathy which causes painful vaso-occlusive crises due to sickle red blood cell dehydration. Vaso-occlusive crises are common painful events responsible for a variety of clinical complications; overall mortality is increased and life expectancy decreased compared to the general population. Experimental studies suggest that intravenous magnesium has proven to be well-tolerated (...) in individuals hospitalised for the immediate relief of acute (sudden onset) painful crisis and has the potential to decrease the length of hospital stay. Some in vitro studies and open studies of long-term oral magnesium showed promising effect on pain relief but failed to show its efficacy. The studies show that oral magnesium therapy may prevent sickle red blood cell dehydration and prevent recurrent painful episodes. There is a need to access evidence for the impact of oral and intravenous magnesium

2019 Cochrane

2. Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis

Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis Clinical trials regarding the antishivering effect of perioperative magnesium have produced inconsistent results. We conducted a systematic review and meta-analysis with Trial Sequential Analysis to evaluate the effect of perioperative magnesium on prevention of shivering.We searched PubMed, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials, and 2 registry sites (...) for randomized clinical trials that compared the administration of magnesium to a placebo or no treatment in patients undergoing surgeries. The primary outcome of this meta-analysis was the incidence of shivering. The incidence of shivering was combined as a risk ratio with 95% CI using a random-effect model. The effect of the route of administration was evaluated in a subgroup analysis, and Trial Sequential Analysis with a risk of type 1 error of 5% and power of 90% was performed. The quality of each

2019 EvidenceUpdates

3. Topical application of magnesium to prevent intubation-related sore throat in adult surgical patients: a systematic review and meta-analysis

Topical application of magnesium to prevent intubation-related sore throat in adult surgical patients: a systematic review and meta-analysis Postoperative sore throat negatively affects patient satisfaction and recovery. We conducted a systematic review and meta-analysis to examine the efficacy of preoperative topical administration of magnesium sulfate in preventing postoperative sore throat in adult patients.We searched Medline, EMBASE, China National Knowledge Infrastructure (...) , and the Cochrane Central Register of Controlled Trials from inception to 6 October, 2018. We included randomized-controlled trials that assessed the efficacy and safety of topical application of magnesium preoperatively in adult patients who underwent endotracheal intubation for general anesthesia. We then pooled the data using a random-effects model and conducted a trial sequential analysis on the incidence of sore throat. Our primary outcome was the incidence of sore throat at 24 hr after surgery/extubation

2019 EvidenceUpdates

4. Intravenous Magnesium Sulfate in Acute Stroke

Intravenous Magnesium Sulfate in Acute Stroke Background and Purpose- Acute stroke treatment is challenging, and stroke remains a major cause of death and disability. The purpose of this meta-analysis is to investigate the effects of postacute stroke intravenous administration of the neuroprotectant magnesium sulfate (MgSO4) on global outcome, functional outcome, and mortality 90 days poststroke (ischemic and nonischemic). Methods- We searched in Pubmed, Science Direct, CENTRAL

2019 EvidenceUpdates

5. Magnesium sulfate: risk of skeletal adverse effects in the neonate following prolonged or repeated use in pregnancy

Magnesium sulfate: risk of skeletal adverse effects in the neonate following prolonged or repeated use in pregnancy Magnesium sulfate: risk of skeletal adverse effects in the neonate following prolonged or repeated use in pregnancy - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Magnesium sulfate: risk of skeletal adverse effects in the neonate following prolonged or repeated use in pregnancy Maternal administration of magnesium sulfate for longer than 5–7 days in pregnancy has (...) been associated with skeletal adverse effects and hypocalcaemia and hypermagnesemia in neonates. If use of magnesium sulfate in pregnancy is prolonged or repeated, consider monitoring of neonates for abnormal calcium and magnesium levels and skeletal adverse effects. Published 17 May 2019 From: Therapeutic area: , , , Contents Advice for healthcare professionals: maternal administration of magnesium sulfate for longer than 5–7 days in pregnancy may be associated with adverse effects in the foetus

2019 MHRA Drug Safety Update

6. Analgesic Potentials of Preoperative Oral Pregabalin, Intravenous Magnesium Sulfate, and their Combination in Acute Postthoracotomy Pain

Analgesic Potentials of Preoperative Oral Pregabalin, Intravenous Magnesium Sulfate, and their Combination in Acute Postthoracotomy Pain The objective of this study was to investigate the effects of the preoperative combination of oral Pregabalin and intravenous (IV) magnesium sulfate as analgesic adjuvants in postthoracotomy pain.One hundred twenty patients with American Society of Anesthesiologists physical status II were allocated randomly into 1 of 4 groups. Group MP received 300 mg (...) pregabalin orally and an IV infusion of magnesium sulfate 50 mg/kg mixed with 200 mL normal saline (NS); group P received 300 mg pregabalin orally and 200 mL NS infusion; group M received an IV infusion of magnesium sulfate 50 mg/kg mixed with 200 mL NS and a placebo capsule; and group C received placebo capsule and an IV infusion of 200 mL NS. All medications were given 1 hour before surgery in all groups. In the first 24 hours postoperatively, total morphine consumption, the Visual Analog Scale (0

2019 EvidenceUpdates

7. Magnesium Sulphate for Fetal Neuroprotection

Magnesium Sulphate for Fetal Neuroprotection No. 376-Magnesium Sulphate for Fetal Neuroprotection - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 41, Issue 4, Pages 505–522 No. 376-Magnesium Sulphate for Fetal Neuroprotection x Laura A. Magee , MD Vancouver, BC x Dane A. De Silva , MPH Vancouver, BC x Diane Sawchuck , RN, PhD Victoria, BC x Anne Synnes , MDCM, MHSc Vancouver, BC x Peter von Dadelszen , MBChB Vancouver (...) , BC No. 376, Month Year (Replaces No. 258, May 2011) DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Figures Figure Magnesium sulphate for fetal neuroprotection in imminent preterm birth (≤33+6 weeks). Abstract Objective The objective is to provide guidelines for the use of antenatal magnesium sulphate for fetal neuroprotection of the preterm infant. Options Antenatal magnesium sulphate administration should be considered for fetal

2019 Society of Obstetricians and Gynaecologists of Canada

8. Serum magnesium as a biomarker predicting the risk of development of preeclampsia

Serum magnesium as a biomarker predicting the risk of development of preeclampsia Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing

2019 PROSPERO

9. The effect and analgesic efficacy of magnesium sulfate as an adjuvant of local anesthetics for perineural nerve blocks: a meta-analysis update

The effect and analgesic efficacy of magnesium sulfate as an adjuvant of local anesthetics for perineural nerve blocks: a meta-analysis update Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne

2019 PROSPERO

10. Effects of oral magnesium supplementation on vascular function: a systematic review and meta-analysis

Effects of oral magnesium supplementation on vascular function: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web

2019 PROSPERO

11. Efficacy of Oral magnesium-based laxatives in reducing the duration of postoperative ileus (POI) and return of gastrointestinal (GI) function after major abdominal surgery - a systematic review

Efficacy of Oral magnesium-based laxatives in reducing the duration of postoperative ileus (POI) and return of gastrointestinal (GI) function after major abdominal surgery - a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears

2019 PROSPERO

12. Systematic review and meta-analysis of correlation of body magnesium levels and migraine

Systematic review and meta-analysis of correlation of body magnesium levels and migraine Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites

2019 PROSPERO

13. The association between serum magnesium and dialysis mortality: a systematic review and meta-analysis

The association between serum magnesium and dialysis mortality: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2019 PROSPERO

14. A systematic review and meta-analysis of antenatal magnesium sulfate in prevention of intraventricular hemorrhage in premature infants

A systematic review and meta-analysis of antenatal magnesium sulfate in prevention of intraventricular hemorrhage in premature infants Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

15. The effect of sodium picosulfate with magnesium citrate versus polyethylene glycol as bowel preparation regimen for colonoscopy: a meta-analysis and systematic review

The effect of sodium picosulfate with magnesium citrate versus polyethylene glycol as bowel preparation regimen for colonoscopy: a meta-analysis and systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

16. Intravenous vs. intramuscular magnesium sulfate for hypertensive disorder in pregnancy: a systematic review and meta-analysis

Intravenous vs. intramuscular magnesium sulfate for hypertensive disorder in pregnancy: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

17. The best magnesium sulfate regimen in preeclampsia prevention

The best magnesium sulfate regimen in preeclampsia prevention Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr

2019 PROSPERO

18. The role of magnesium for postoperative pain control in patients undergoing abdominal hysterectomy

The role of magnesium for postoperative pain control in patients undergoing abdominal hysterectomy Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external

2019 PROSPERO

19. Intravenous magnesium sulfate therapy in adult patients with an aneurysmal subarachnoid haemorrhage: a systematic review and meta-analysis

Intravenous magnesium sulfate therapy in adult patients with an aneurysmal subarachnoid haemorrhage: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

20. A rapid systematic review on implementation approaches that address barriers and facilitators on the use of magnesium sulfate (MgSO4) treatment for management of hypertensive disorder in pregnancy

A rapid systematic review on implementation approaches that address barriers and facilitators on the use of magnesium sulfate (MgSO4) treatment for management of hypertensive disorder in pregnancy Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears

2019 PROSPERO