Latest & greatest articles for menopause

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Top results for menopause

241. Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome. (PubMed)

Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome. The risks of multiple pregnancy and ovarian hyperstimulation syndrome (OHSS) are increased in women with clomiphene resistance WHO group 2 dysfunction undergoing ovulation induction as well as the risk of spontaneous abortion if conception takes place. Semi-purified preparations of FSH have been developed in an effort to reduce the impact (...) of exogenous LH, relatively high levels of which are present in human menopausal gonadotropin (hMG). Ovulation induction in women with clomiphene resistant WHO group 2 dysfunction who often have clinical features of polycystic ovarian syndrome (PCOS), is a major challenge. The risks of multiple pregnancy and ovarian hyperstimulation syndrome (OHSS) are increased in this population. There also appears to be an increased risk of spontaneous abortion in those who conceive, perhaps associated with elevated LH

2000 Cochrane

242. Estrogen and progestin, lipoprotein(a), and the risk of recurrent coronary heart disease events after menopause. (PubMed)

Estrogen and progestin, lipoprotein(a), and the risk of recurrent coronary heart disease events after menopause. Lipoprotein(a) [Lp(a)] has been identified as an independent risk factor for coronary heart disease (CHD) events. However, few data exist on the clinical importance of Lp(a) lowering for CHD prevention. Hormone therapy with estrogen has been found to lower Lp(a) levels in women.To determine the relationships among treatment with estrogen and progestin, serum Lp(a) levels

2000 JAMA

243. Follicle-stimulating hormone or human menopausal gonadotropin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis

Follicle-stimulating hormone or human menopausal gonadotropin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis Follicle-stimulating hormone or human menopausal gonadotropin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis Follicle-stimulating hormone or human menopausal gonadotropin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis Agrawal R, Holmes J, Jacobs H S Authors' objectives To re-analyse the results of using (...) follicle-stimulating hormone (FSH) and human menopausal gonadotropin (hMG) during in vitro fertilisation (IVF) treatment, taking into account the different protocols of administration of superactive gonadotropin-releasing hormone (GnRH) analogues (short, long protocol, or no GnRH analog). Searching The authors searched MEDLINE from January 1985 to 1999 using a combination of the keywords 'FSH', 'LH', 'hMG', 'gonadotropins', 'IVF' and 'comparison'. Review articles and abstracts of major scientific

2000 DARE.

244. Efficacy and acceptability of intranasal 17 beta-oestradiol for menopausal symptoms: randomised dose-response study. Aerodiol Study Group. (PubMed)

Efficacy and acceptability of intranasal 17 beta-oestradiol for menopausal symptoms: randomised dose-response study. Aerodiol Study Group. The benefit of oestrogen therapy for menopause symptoms is well recognised. However, the means of delivery currently available have disadvantages, including variable bioavailability, intestinal and hepatic first-pass effects, and dermatological reactions. An intranasal 17beta-oestradiol spray, S21400, which bypasses such drawbacks, has been developed. We (...) . There was no significant difference in ear, nose, and throat function or adverse events between the S21400 and the placebo or oral oestradiol groups, except for a greater incidence of sneezing and application site reaction (99% mild or moderate) in the S21400 groups. S21400 was thought to be effective and convenient by the patients, and compliance was high.Intranasally administered 17beta-oestradiol is significantly better than placebo; its effectiveness at reducing menopausal symptoms is similar to that of oral

1999 Lancet

245. Traitement hormonal substitutif de la menopause et risque d'accident vasculaire cerebral [Hormone replacement therapy in menopause and the risk of stroke]

Traitement hormonal substitutif de la menopause et risque d'accident vasculaire cerebral [Hormone replacement therapy in menopause and the risk of stroke] Traitement hormonal substitutif de la menopause et risque d'accident vasculaire cerebral [Hormone replacement therapy in menopause and the risk of stroke] Traitement hormonal substitutif de la menopause et risque d'accident vasculaire cerebral [Hormone replacement therapy in menopause and the risk of stroke] Oger E, Scarabin P Y Authors (...) : The authors state that only a randomised controlled trial will prove causation, rather than association, between HRT and the risk of ischaemic stroke. There is also a need to investigate the transdermal administration of HRT. Bibliographic details Oger E, Scarabin P Y. Traitement hormonal substitutif de la menopause et risque d'accident vasculaire cerebral [Hormone replacement therapy in menopause and the risk of stroke] Annales d'Endocrinologie 1999; 60(3): 232-241 PubMedID Indexing Status Subject

1999 DARE.

246. Education intervention designed to reduce risk factors for the development of osteoporosis and subsequent fragility fractures in post menopausal women

Education intervention designed to reduce risk factors for the development of osteoporosis and subsequent fragility fractures in post menopausal women Education intervention designed to reduce risk factors for the development of osteoporosis and subsequent fragility fractures in post menopausal women Education intervention designed to reduce risk factors for the development of osteoporosis and subsequent fragility fractures in post menopausal women Morley D C, Wheatley T Authors' objectives (...) . Studies that focused on an exercise, pharmaceutical or nutritional component without reference to an educational component were excluded. Participants included in the review Healthy post-menopausal women with untreated osteoporosis or significant osteopenia requiring health care intervention. Most of the women included in the review were aged 50-75 years. Outcomes assessed in the review All outcome measures were included, with emphasis on the following: knowledge about osteoporosis and related issues

1999 DARE.

247. Meta-analysis about efficacy of anti-resorptive drugs in post-menopausal osteoporosis

Meta-analysis about efficacy of anti-resorptive drugs in post-menopausal osteoporosis Meta-analysis about efficacy of anti-resorptive drugs in post-menopausal osteoporosis Meta-analysis about efficacy of anti-resorptive drugs in post-menopausal osteoporosis Macedo J M, Macedo C R, Elkis H, De Oliveira I R Authors' objectives To compare the effect of three groups of anti-resorptive drugs in post-menopausal osteoporosis. Searching MEDLINE was searched from 1983 to 1995 (keywords given). Source (...) references of retrieved articles were analysed. Study selection Study designs of evaluations included in the review Randomised controlled trials including a placebo arm, in which treatment and follow-up lasted at least a year. Specific interventions included in the review The inclusion criteria stated oestrogens, calcitonins, biphosphonates and placebo. Estradiol valerate and 17-beta-estradiol were specifically mentioned in the review. Participants included in the review Patients with post-menopausal

1998 DARE.

248. WITHDRAWN: Follicle-stimulating hormone and human menopausal gonadotropin for ovarian stimulation in assisted reproduction cycles. (PubMed)

WITHDRAWN: Follicle-stimulating hormone and human menopausal gonadotropin for ovarian stimulation in assisted reproduction cycles. Both human menopausal gonadotropin (hMG) and human follicle stimulating hormone (hFSH) have been used successfully for ovarian stimulation, but the relative importance of FSH and luteinizing hormone (LH) in follicular growth and maturation has been the subject of much debate.To conduct a systematic overview of available data comparing FSH and hMG in IVF treatment

1996 Cochrane

249. WITHDRAWN: Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome. (PubMed)

WITHDRAWN: Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome. The risks of multiple pregnancy and ovarian hyperstimulation syndrome (OHSS) are increased in women with clomiphene resistance WHO group 2 dysfunction undergoing ovulation induction as well as the risk of spontaneous abortion if conception takes place. Semi-purified preparations of FSH have been developed in an effort to reduce (...) the impact of exogenous LH, relatively high levels of which are present in human menopausal gonadotropin (hMG). Ovulation induction in women with clomiphene resistant WHO group 2 dysfunction who often have clinical features of polycystic ovarian syndrome (PCOS), is a major challenge. The risks of multiple pregnancy and ovarian hyperstimulation syndrome (OHSS) are increased in this population. There also appears to be an increased risk of spontaneous abortion in those who conceive, perhaps associated

1996 Cochrane

250. Pathological complications of menopause. IPE-95/03 (Public report)

Pathological complications of menopause. IPE-95/03 (Public report) Pathological complications of menopause. IPE-95/03 (Public report) Pathological complications of menopause. IPE-95/03 (Public report) Sez A, Conde J, Ruiz F, Cuadrado C, Saiz J, Sancho J Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Sez A, Conde J, Ruiz F, Cuadrado C (...) , Saiz J, Sancho J. Pathological complications of menopause. IPE-95/03 (Public report) Agencia de Evaluacion de Tecnologias Sanitarias (AETS). 1995 Authors' objectives According to the recent Royal Decree (Real Decreto) which establishes the basic public coverage of health care, pathological complications of menopause must be specifically covered. The issue raised by the Ministry of Health is to establish the content of this definition and the necessity to find a specific build-up, procedures

1995 Health Technology Assessment (HTA) Database.

251. Follicle-stimulating hormone versus human menopausal gonadotropin for in vitro fertilization cycles: a meta-analysis

Follicle-stimulating hormone versus human menopausal gonadotropin for in vitro fertilization cycles: a meta-analysis Follicle-stimulating hormone versus human menopausal gonadotropin for in vitro fertilization cycles: a meta-analysis Follicle-stimulating hormone versus human menopausal gonadotropin for in vitro fertilization cycles: a meta-analysis Daya S, Gunby J, Hughes E G, Collins J A, Sagle M A Authors' objectives To conduct a systematic overview of available data comparing follicle (...) -stimulating hormone (FSH) with human menopausal gonadotropin (hMG) in in vitro fertilisation (IVF) cycles and gamete intra-fallopian transfer (GIFT) cycles. Searching MEDLINE was searched from 1975 to 1993 using MeSH terms (terms given). Bibliographies of relevant publications and review articles were scanned and abstracts of major scientific meetings from 1983 to 1993 were handsearched. Authors of relevant abstracts were contacted as were peer reviewers. Study selection Study designs of evaluations

1995 DARE.

252. Effect of oral gamolenic acid from evening primrose oil on menopausal flushing. (PubMed)

Effect of oral gamolenic acid from evening primrose oil on menopausal flushing. To evaluate the efficacy of gamolenic acid provided by evening primrose oil in treating hot flushes and sweating associated with the menopause.Randomised, double blind, placebo controlled study.District general hospital and teaching hospital.56 menopausal women suffering hot flushes at least three times a day.Four capsules twice a day of 500 mg evening primrose oil with 10 mg natural vitamin E or 500 mg liquid (...) ; the corresponding values for women taking gamolenic acid were 0.5 (0.4) and 0.5 (0.3). In women taking gamolenic acid the only significant improvement was a reduction in the maximum number of night time flushes (1.4 (0.6); P < 0.05).Gamolenic acid offers no benefit over placebo in treating menopausal flushing.

Full Text available with Trip Pro

1994 BMJ

253. The efficacy and cost-effectiveness of adjuvant therapy of early breast cancer in pre-menopausal women

The efficacy and cost-effectiveness of adjuvant therapy of early breast cancer in pre-menopausal women The efficacy and cost-effectiveness of adjuvant therapy of early breast cancer in pre-menopausal women The efficacy and cost-effectiveness of adjuvant therapy of early breast cancer in pre-menopausal women Smith T J, Hillner B E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Adjuvant tamoxifen with or without chemotherapy for early breast cancer in pre-menopausal women. Type of intervention Secondary prevention. Economic study type Cost-effectiveness and cost-utility analysis. Study population Women aged 45 years with early breast cancer, eligible for trials of alternative cancer treatments included in the review

1993 NHS Economic Evaluation Database.

254. Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause. (PubMed)

Cigarette smoking, serum estrogens, and bone loss during hormone-replacement therapy early after menopause. To elucidate the effect of smoking on estrogen metabolism, we examined 136 postmenopausal women treated for one year with one of three different doses of combined estrogen-progestogen or placebo. The women were grouped according to smoking status, and serum levels of estrone and estradiol were measured before and after treatment. The results showed reduced levels of both estrogens

1985 NEJM