Latest & greatest articles for nsaids

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Top results for nsaids

41. Systematic review: No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury

Systematic review: No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury Article Text Pain management Systematic review No difference

2016 Evidence-Based Nursing

42. Randomised controlled trial: NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent?

Randomised controlled trial: NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) , please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis

2016 Evidence-Based Medicine (Requires free registration)

43. Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen

Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Prescrire IN ENGLISH - Spotlight ''Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen'', 1 January 2016 {1} {1} {1} | | > > > Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |  (...)  |   |   |   |   |   |   |  Spotlight Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen When pain medication is required, paracetamol (alias acetaminophen) is the reference drug. Among the nonsteroidal anti-inflammatories (NSAIDs), naproxen or ibuprofen (not exceeding 1200 mg a day) are the drugs that carry the least exposure to cardiac disorders. When pain medication is needed

2016 Prescrire

44. NSAIDs: Inflamed effects on inflammation?

NSAIDs: Inflamed effects on inflammation? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,000 family physicians, family medicine residents and medical students in Alberta. Established over fifty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research. www.acfp.ca March 29, 2016 NSAIDs (...) : Inflamed effects on inflammation? Clinical Question: Do non-steroidal anti-inflammatory drugs (NSAIDs) reduce swelling and inflammation in acute injury? Bottom Line: Randomized Controlled Trials (RCTs) of NSAIDs effect on musculoskeletal injury swelling show highly inconsistent results: Some slight improvements (2-11%), some slight worsening (8%) and most no effect. It is unlikely NSAIDs have any reliable effect on acute injury swelling but they do improve pain for ~1 in 4 over one week. Evidence

2016 Tools for Practice

45. Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial. (Full text)

Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial. For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoided because they may reduce pleurodesis efficacy. Smaller chest tubes may be less painful than larger tubes, but efficacy in pleurodesis has not been proven.To assess the effect of chest tube size (...) and analgesia (NSAIDs vs opiates) on pain and clinical efficacy related to pleurodesis in patients with malignant pleural effusion.A 2×2 factorial phase 3 randomized clinical trial among 320 patients requiring pleurodesis in 16 UK hospitals from 2007 to 2013.Patients undergoing thoracoscopy (n = 206; clinical decision if biopsy was required) received a 24F chest tube and were randomized to receive opiates (n = 103) vs NSAIDs (n = 103), and those not undergoing thoracoscopy (n = 114) were randomized to 1

2015 JAMA PubMed

46. For Patients Undergoing Open-Flap Debridement Surgery, There is No Significant Difference Between Dexamethasone and NSAIDs For Reducing Patient Perceived Pain

For Patients Undergoing Open-Flap Debridement Surgery, There is No Significant Difference Between Dexamethasone and NSAIDs For Reducing Patient Perceived Pain UTCAT2956, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title For Patients Undergoing Open-Flap Debridement Surgery, There is No Significant Difference Between Dexamethasone and NSAIDs For Reducing Patient Perceived Pain Clinical Question In adults undergoing (...) periodontal surgery, what is the effect of dexamethasone on patient perceived pain as compared to traditional non-steroidal anti-inflammatories? Clinical Bottom Line Dexamethasone and NSAIDs are equally effective in reducing patient perceived pain following periodontal open flap debridement surgeries. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Steffens/2010 15 adult patients receiving periodontal surgery

2015 UTHSCSA Dental School CAT Library

47. Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis). (PubMed)

Non-steroidal anti-inflammatory drugs (NSAIDs) for axial spondyloarthritis (ankylosing spondylitis and non-radiographic axial spondyloarthritis). Axial spondyloarthritis (axSpA) comprises ankylosing spondylitis (radiographic axSpA) and non-radiographic (nr-)axSpA and is associated with psoriasis, uveitis and inflammatory bowel disease. Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as first-line drug treatment.To determine the benefits and harms of NSAIDs in axSpA.We searched (...) CENTRAL, MEDLINE and EMBASE to 18 June 2014.Randomised controlled trials (RCTs) or quasi-RCTs of NSAIDs versus placebo or any comparator in adults with axSpA and observational cohort studies studying the long term effect (≥ six months) of NSAIDs on radiographic progression or adverse events (AEs). The main comparions were traditional or COX-2 NSAIDs versus placebo. The major outcomes were pain, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index

2015 Cochrane

48. Nonsteroidal anti-inflammatory drugs (NSAIDs) and non-opioids for acute renal colic. (PubMed)

Nonsteroidal anti-inflammatory drugs (NSAIDs) and non-opioids for acute renal colic. Renal colic is acute pain caused by urinary stones. The prevalence of urinary stones is between 10% and 15% in the United States, making renal colic one of the common reasons for urgent urological care. The pain is usually severe and the first step in the management is adequate analgesia. Many different classes of medications have been used in this regard including non-steroidal anti-inflammatory drugs (...) and narcotics.The aim of this review was to assess benefits and harms of different NSAIDs and non-opioids in the treatment of adult patients with acute renal colic and if possible to determine which medication (or class of medications) are more appropriate for this purpose. Clinically relevant outcomes such as efficacy of pain relief, time to pain relief, recurrence of pain, need for rescue medication and side effects were explored.We searched the Cochrane Renal Group's Specialised Register (to 27 November 2014

2015 Cochrane

49. Topical NSAIDs: good relief for acute musculoskeletal pain

Topical NSAIDs: good relief for acute musculoskeletal pain Topical NSAIDs: good relief for acute musculoskeletal pain - Evidently Cochrane Search and hit Go By June 25, 2015 // Non-steroidal anti-inflammatory drugs (NSAIDs) are routinely prescribed for mild to moderate pain and are the most commonly prescribed painkilling drugs worldwide. Taken by mouth or injected into a vein, the high concentrations of the drug throughout the body, necessary in order to work at the site of pain (...) and inflammation, can cause unpleasant or even serious side effects. Applied to the skin, so in a topical preparation such as a gel, cream or plaster, they can act where needed to relieve pain without affecting the rest of the body. For superficial painful conditions like sprains, strains and muscle soreness (and where the skin is unbroken) topical NSAIDs offer this clear advantage over taking tablets, as long as they work. How good are topical NSAIDs? A has been updated with new research confirming

2015 Evidently Cochrane

50. Topical NSAIDs for acute musculoskeletal pain in adults. (PubMed)

Topical NSAIDs for acute musculoskeletal pain in adults. Use of topical NSAIDs to treat acute musculoskeletal conditions has become widely accepted because they can provide pain relief without associated systemic adverse events. This review is an update of 'Topical NSAIDs for acute pain in adults' originally published in Issue 6, 2010.To determine the efficacy and safety of topically applied NSAIDs in acute musculoskeletal pain in adults.We searched the Cochrane Register of Studies Online (...) particularly interested to compare different formulations (gel, cream, plaster) of individual NSAIDs.For this update we added 14 new included studies (3489 participants), and excluded four studies. We also identified 20 additional reports of completed or ongoing studies that have not been published in full. The earlier review included 47 studies.This update included 61 studies. Most compared topical NSAIDs in the form of a gel, spray, or cream with a similar topical placebo; 5311 participants were treated

2015 Cochrane

51. Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants. (Full text)

Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants. Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with lower risk of colorectal cancer.To identify common genetic markers that may confer differential benefit from aspirin or NSAID chemoprevention, we tested gene × environment interactions between regular use of aspirin and/or NSAIDs and single-nucleotide polymorphisms (SNPs) in relation to risk of colorectal (...) cancer.Case-control study using data from 5 case-control and 5 cohort studies initiated between 1976 and 2003 across the United States, Canada, Australia, and Germany and including colorectal cancer cases (n=8634) and matched controls (n=8553) ascertained between 1976 and 2011. Participants were all of European descent.Genome-wide SNP data and information on regular use of aspirin and/or NSAIDs and other risk factors.Colorectal cancer.Regular use of aspirin and/or NSAIDs was associated with lower risk

2015 JAMA PubMed

52. Cohort study: NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy

Cohort study: NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy Article Text Aetiology/Harm Cohort study NSAIDs increase bleeding risk in patients with atrial

2015 Evidence-Based Medicine (Requires free registration)

53. Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery

Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Swedish Agency for Health Technology Assessment and Assessment of Social Services Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery Share (...) : Reading time approx. 4 minutes This document was published more than 2 years ago. The nature of the evidence may have changed. NSAIDs are a class of drugs that are anti-inflammatory, analgesic and antipyretic but which also leads to an increased risk of bleeding. SBU Enquiry Service consists of systematic literature searches to highlight studies that can address questions received by the SBU Enquiry Service from Swedish healthcare or social service providers. Relevant references are compiled by an SBU

2015 Swedish Council on Technology Assessement

54. Corticosteroid Injections Accelerate Pain Relief and Recovery of Function Compared With Oral NSAIDs in Patients With Adhesive Capsulitis: A Randomized Controlled Trial (PubMed)

Corticosteroid Injections Accelerate Pain Relief and Recovery of Function Compared With Oral NSAIDs in Patients With Adhesive Capsulitis: A Randomized Controlled Trial Intra-articular corticosteroid injection is a common therapy for adhesive capsulitis, but there is a lack of prospective randomized controlled studies analyzing the efficacy of single injections applied blindly to accelerate improvement in pain and function.In patients with adhesive capsulitis, a single intra-articular (...) corticosteroid injection without image control applied before the beginning of a physical therapy program will accelerate pain relief and recovery of function compared with oral nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy.Randomized controlled trial; Level of evidence, 1.A total of 74 patients with primary adhesive capsulitis in the freezing stage were randomized to receive either intra-articular injections with betamethasone or oral NSAIDs. Clinical outcome was documented at baseline

2015 EvidenceUpdates

55. NSAIDs

NSAIDs USE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) IN PREGNANCY 0344 892 0909 USE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) IN PREGNANCY (Date of issue: August 2014 , Version: 2 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . Summary Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat (...) pain and inflammation in various disease states. NSAID use in pregnancy has been associated with increased risks of various different congenital malformations, including cardiovascular defects and oral clefts, as well as an increased risk of spontaneous abortion. However, the available data are conflicting and limited, and firm associations are yet to be concluded. The available data on NSAID use in pregnancy does not suggest an association with stillbirth, low infant birth weight or preterm

2014 UK Teratology Information Service

56. Cohort study: In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated with increased risk of quadriparetic cerebral palsy

Cohort study: In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated with increased risk of quadriparetic cerebral palsy In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated with increased risk of quadriparetic cerebral palsy | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we (...) use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated

2014 Evidence-Based Nursing

57. Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern

Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Article Text Aetiology Cohort study

2014 Evidence-Based Medicine (Requires free registration)

58. Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing

Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing Tsertsvadze A, Leas B, Umscheid CA Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Tsertsvadze A, Leas B, Umscheid (...) CA. Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing. Philadelphia: Center for Evidence-based Practice (CEP). 2013 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Anti-Inflammatory Agents, Non-Steroidal; Fracture Healing; Fractures, Bones Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University

2013 Health Technology Assessment (HTA) Database.

59. Use of NSAIDs to provide symptomatic relief in uncomplicated UTI.

Use of NSAIDs to provide symptomatic relief in uncomplicated UTI. BestBets: Use of NSAIDs to provide symptomatic relief in uncomplicated UTI. Use of NSAIDs to provide symptomatic relief in uncomplicated UTI. Report By: Henry Lewith - FY2 Search checked by Jonathan Costello - Consultant - Royal Free Hospital A+E Institution: University College Hospital Date Submitted: 5th June 2012 Date Completed: 17th April 2013 Last Modified: 17th April 2013 Status: Green (complete) Three Part Question (...) In [an female patient with an uncomplicated Urinary Tract Infection] are [NSAIDs better than Antibiotics] in [providing symptomatic relief]? Clinical Scenario A 44 year old female attends the Emergency Department with a two day history of worsening dysuria and urinary frequency. She is systemically well, but urinary dipstick testing confirms the presence of a urinary tract infection. The patient states that she does not want to take antibiotics and you wonder whether NSAIDs will provide adequate relief

2013 BestBETS

60. NSAIDs were associated with increased risk for mortality, regardless of time since first MI. (PubMed)

NSAIDs were associated with increased risk for mortality, regardless of time since first MI. 23318332 2013 03 11 2013 01 15 1539-3704 158 2 2013 Jan 15 Annals of internal medicine Ann. Intern. Med. ACP Journal Club. NSAIDs were associated with increased risk for mortality, regardless of time since first MI. JC10 10.7326/0003-4819-158-2-201301150-02010 Belknap Steven M SM Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. eng Comment Journal Article United States Ann

2013 Annals of Internal Medicine