Latest & greatest articles for nsaids

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Top results for nsaids

81. ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused Update of the ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID

ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused Update of the ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID nature publishing group the red section 2533 Writing Committee Members Neena S. Abraham, MD, FACG, Chair*; Mark A. Hlatky, MD, FACC, FAHA, Vice Chair† Elliott M. Antman, MD, FACC, FAHA‡; Deepak L. Bhatt, MD, MPH, FACC, FAHA† David J. Bjorkman (...) KW , Quigley EM, Scheiman J, Sper - ling LS, Tomaselli GF (. ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. Am J Gastroenterol 2010;105:2533–2549; doi:10.1038/ajg.2010.445. This article has been copublished in the Journal of the American College of Cardiology and Circulation. Copies

2010 American College of Gastroenterology

82. Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side (...) -effects after major surgery: a systematic review McDaid C, Maund E, Rice S, Wright K, Jenkins B, Woolacott N Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation McDaid C, Maund E, Rice S, Wright K, Jenkins B, Woolacott N. Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related

2010 Health Technology Assessment (HTA) Database.

83. Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis

Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis Jansen JP, Gaugris S, Choy EH, Ostor A, Nash JT, Stam W Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study evaluated the cost-effectiveness of etoricoxib compared with celecoxib, diclofenac, and naproxen for patients with ankylosing spondylitis, who required routine non-steroidal anti-inflammatory drug (NSAID) treatment. The authors concluded that their economic

2010 NHS Economic Evaluation Database.

84. Systematic review: NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects

Systematic review: NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects Article Text Therapeutics Systematic

2010 Evidence-Based Nursing

85. Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis. (PubMed)

Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis. To investigate the cost effectiveness of cyclo-oxygenase-2 (COX 2) selective inhibitors and traditional non-steroidal anti-inflammatory drugs (NSAIDs), and the addition of proton pump inhibitors to these treatments, for people with osteoarthritis.An economic evaluation using a Markov model and data from a systematic review was conducted (...) . Subgroup analyses were conducted for people at high risk of gastrointestinal or cardiovascular adverse events. Comparators Licensed COX 2 selective inhibitors (celecoxib and etoricoxib) and traditional NSAIDs (diclofenac, ibuprofen, and naproxen) for which suitable data were available were compared. Paracetamol was also included, as was the possibility of adding a proton pump inhibitor (omeprazole) to each treatment.The main outcome measure was cost effectiveness, which was based on quality adjusted

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2009 BMJ

86. NSAIDs and the risk of accidental falls in the elderly: a systematic review

NSAIDs and the risk of accidental falls in the elderly: a systematic review NSAIDs and the risk of accidental falls in the elderly: a systematic review NSAIDs and the risk of accidental falls in the elderly: a systematic review Hegeman J, van den Bemt BJ, Duysens J, van Limbeek J CRD summary This review concluded that an increased risk of falls was probable when elderly individuals were exposed to NSAIDs. The lack of controlled trials and the likelihood of recall bias were important limitations (...) of the review and made it difficult to verify results, but the authors' conclusions appeared to reflect the evidence presented. Authors' objectives To investigate the risk of accidental falls due to NSAID use in elderly people. Searching Published trials were identified through a search of PubMed, EMBASE, Cochrane Database of Systematic Reviews, Excerpta Medica, Current Contents and Science Citation Index from 1966 to March 2008. Articles were required to be in English, German or Dutch. Reference lists

2009 DARE.

87. Effectiveness and tolerability of NSAIDs in the prophylaxis of pancreatitis after endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis

Effectiveness and tolerability of NSAIDs in the prophylaxis of pancreatitis after endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

88. Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated meta-analysis

Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

89. Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis

Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

90. NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies

NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

91. Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis

Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 NHS Economic Evaluation Database.

92. Use of NSAIDs and infection with Helicobacter pylori--what does the rheumatologist need to know? (PubMed)

Use of NSAIDs and infection with Helicobacter pylori--what does the rheumatologist need to know? NSAID-induced gastroduodenal lesions are a frequent and potentially serious health problem in patients with rheumatic diseases. Helicobacter pylori (H. pylori) has also been recognized as a major risk factor for the development of ulcer disease. However, the role of H. pylori in the pathogenesis of NSAID-induced gastroduodenal lesions has remained controversial, and there is currently no clear (...) consensus on the management of NSAID users who are infected with H. pylori.To clarify this situation we have performed a systematic literature search to find randomized controlled trials comparing the efficacy of eradication in patients receiving NSAIDs to prevent ulcer development.Seven randomized controlled trials and one meta-analysis were identified. There were three papers on NSAID-naive patients. According to this data, NSAID-naive users benefit from testing for H. pylori infection and subsequent

Full Text available with Trip Pro

2008 EvidenceUpdates

93. A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis (PubMed)

A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis Several pharmacological agents for the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) have been studied. Clinical trials evaluating the protective effect of non-steroidal anti-inflammatory drugs (NSAIDs) have yielded inconclusive results.To perform a meta-analysis of studies evaluating the effect of prophylactic rectal NSAIDs on PEP.By searching Medline, Embase, meeting (...) abstracts and bibliographies, two independent reviewers systematically identified prospective randomised controlled trials (RCTs) examining the effect of rectally administered prophylactic NSAIDs on the incidence of PEP pancreatitis. A meta-analysis of these clinical trials was performed.Four RCTs, enrolling a total of 912 patients, have been published. Meta-analysis of these studies demonstrates a pooled relative risk for PEP after prophylactic administration of NSAIDs of 0.36 (95% CI 0.22 to 0.60

2008 EvidenceUpdates

94. Review: diacerein is more effective than placebo and is as effective as NSAIDs for knee and hip osteoarthritis

Review: diacerein is more effective than placebo and is as effective as NSAIDs for knee and hip osteoarthritis Review: diacerein is more effective than placebo and is as effective as NSAIDs for knee and hip osteoarthritis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: diacerein is more effective than placebo and is as effective as NSAIDs for knee and hip osteoarthritis Article Text Therapeutics Review: diacerein is more

2008 Evidence-Based Medicine (Requires free registration)

95. Influences on older people's decision making regarding choice of topical or oral NSAIDs for knee pain: qualitative study. (PubMed)

Influences on older people's decision making regarding choice of topical or oral NSAIDs for knee pain: qualitative study. To explore the factors that influence older people's decision making regarding use of topical or oral ibuprofen for their knee pain.Qualitative interview study nested within a randomised controlled trial and a patient preference study that compared advice to use oral or topical non-steroidal anti-inflammatory drugs (NSAIDs) for knee pain in older people.11 general practices (...) .30 people aged > or =50 with knee pain.Participants' decision making was influenced by their perceptions of the associated risk of adverse effects, presence of other illness, nature of their pain, advice received, and practicality. Although participants' understanding of how the medications worked was sometimes poor their decision making about the use of NSAIDs seemed logical and appropriate. Participants' model for treatment was to use topical NSAIDs for mild, local, and transient pain and oral

Full Text available with Trip Pro

2008 BMJ

96. A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis

A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis Elmunzer BJ, Waljee AK, Elta GH, Taylor JR, Fehmi SM, Higgins PD CRD summary The authors concluded that, in this meta-analysis, prophylactic rectal non-steroidal anti-inflammatory drugs were effective in preventing post-endoscopic retrograde cholangiopancreatography (...) pancreatitis, but further studies are needed to confirm these findings before their use becomes widespread. Overall, this was a well-conducted review and the authors’ conclusions are likely to be reliable. Authors' objectives To evaluate the effect of prophylactic rectal non-steroidal anti-inflammatory drugs (NSAIDs) for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). Searching MEDLINE and EMBASE were searched from 1966 to December 2007. Search terms were reported

2008 DARE.

97. Major malformations after first-trimester exposure to aspirin and NSAIDs

Major malformations after first-trimester exposure to aspirin and NSAIDs Major malformations after first-trimester exposure to aspirin and NSAIDs Major malformations after first-trimester exposure to aspirin and NSAIDs Nakhai-Pour HR, Berard A CRD summary The authors concluded that exposure to aspirin or NSAIDs during the first trimester of pregnancy was associated with the risk of gastroschisis (aspirin), cardiac malformations (NSAIDs) and orofacial malformations (naproxen). The authors (...) ' conclusion reflected the evidence presented. However, due to a lack of validity assessment and reliance upon observational studies, the reliability of the authors conclusions is unclear. Authors' objectives To determine if there is an association between aspirin and non-steroidal anti-inflammatory drug (NSAID) use and the risk of congenital malformations Searching MEDLINE (1966-2008), EMBASE (1980-2008), EBM reviews, DARE and Cochrane Database of Systematic Reviews were searched for studies in any

2008 DARE.

98. Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: a systematic review and meta-analysis

Sinomenine versus NSAIDs for the treatment of rheumatoid arthritis: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

99. Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy - a randomized study comparing ranitidine with esomeprazole (PubMed)

Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy - a randomized study comparing ranitidine with esomeprazole BACKGROUND: The use of non-steroidal anti-inflammatory drugs (NSAID) is associated with an increased risk of gastric ulcer (GU) development. METHODS: This multicentre, randomized, double-blind, parallel-group trial compared endoscopic healing rates at 4 and 8 weeks after treatment with oral esomeprazole 40 or 20 mg once daily, or ranitidine (...) 150 mg twice daily, in patients with 1 baseline GU > or = 5 mm but no GUs or duodenal ulcers >25 mm in diameter who received continued cyclooxygenase-2-selective or non-selective NSAID therapies. The primary outcome was the percentage of patients in each treatment group who had no GUs at week 8. RESULTS: Four hundred and forty patients were randomized to treatment. At week 8, GU healing rates (95% CI) with esomeprazole 40 mg, esomeprazole 20 mg and ranitidine were 85.7 (79.8-91.7)%, 84.8

Full Text available with Trip Pro

2007 EvidenceUpdates

100. Using non-steroidal anti-inflammatory drugs (NSAIDs) following pleurodesis

Using non-steroidal anti-inflammatory drugs (NSAIDs) following pleurodesis BestBets: Using non-steroidal anti-inflammatory drugs (NSAIDs) following pleurodesis Using non-steroidal anti-inflammatory drugs (NSAIDs) following pleurodesis Report By: Ian Hunt, Elaine Teh, Rachel Southon - Specialist Registrars in Cardiothoracic Surgery Search checked by Tom Treasure - Library Services Manager, Royal Surrey County Hospital, Guildford Institution: Department of Thoracic Surgery, Guy's Hospital (...) and Department of Cardiothoracic Surgery, Brompton, London Date Submitted: 6th February 2007 Date Completed: 9th May 2007 Last Modified: 9th May 2007 Status: Green (complete) Three Part Question In [patients undergoing pleurodesis] is the use of [NSAIDs] detrimental in terms of [successful pleurodesis]. Clinical Scenario A 25 year old man with his second spontaneous right-sided pneumothorax has undergone VATS bullectomy and talc pleurodesis this morning. Patient controlled analgesia (PCA) was set up

2007 BestBETS