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Osteoporosis - prevention of fragility fractures Osteoporosis - prevention of fragility fractures - NICE CKS Clinical Knowledge Summaries Share Osteoporosis - prevention of fragility fractures: Summary Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture. Osteoporosis itself is asymptomatic and often remains undiagnosed until a fragility fracture occurs. An osteoporotic (...) fracture is a fragility fracture occurring as a consequence of increased bone fragility caused by osteoporosis. Characteristically fractures occur in the wrist, spine, and hip. A fragility fracture is defined as a fracture following a fall from standing height or less, although vertebral fractures may occur spontaneously, or as a result of routine activities. In England and Wales, it is estimated that annually around 180,000 fractures occur as a result of osteoporosis. Risk factors for osteoporosis
American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis ENDOCRINE PRACTICE Vol 22 (Suppl 4) September 2016 1 AACE/ACE Guidelines AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY CLINICAL PRACTICE GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF POSTMENOPAUSAL OSTEOPOROSIS — 2016 Pauline M. Camacho, MD, FACE; Steven M. Petak, MD, MACE (...) University Osteoporosis and Metabolic Bone Disease Center, Chicago, IL; 2 Associate Clinical Professor Weill-Cornell Medical College, Division Head Endocrinology and Chief of Endocrinology, Houston Methodist Hospital, Houston, TX; 3 School of Medicine and Public Health, University of Wisconsin, Madison, WI; 4 Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, MN; 5 Clinical Professor of Medicine, University of California, San Francisco; 6 Division of Endocrinology
Osteoporosis and Bone Mineral Density Date of origin: 1998 Last review date: 2016 ACR Appropriateness Criteria ® 1 Osteoporosis and Bone Mineral Density American College of Radiology ACR Appropriateness Criteria ® Clinical Condition: Osteoporosis and Bone Mineral Density Variant 1: Asymptomatic BMD screening or individuals with established or clinically suspected low BMD. 1. All women age 65 years and older and men age 70 years and older (asymptomatic screening) 2. Women younger than age 65 (...) years who have additional risk for osteoporosis, based on medical history and other findings. Additional risk factors for osteoporosis include: a. Estrogen deficiency b. A history of maternal hip fracture that occurred after the age of 50 years c. Low body mass ( 1 year before age 42 years) 3. Women younger than age 65 years or men younger than age 70 years who have additional risk factors, including: a. Current use of cigarettes b. Loss of height, thoracic kyphosis 4. Individuals of any age
Informing evidence-based clinical practice guidelines for children with cerebral palsy at risk of osteoporosis: an update Informing evidence‐based clinical practice guidelines for children with cerebral palsy at risk of osteoporosis: an update - Ozel - 2016 - Developmental Medicine & Child Neurology - Wiley Online Library The full text of this article hosted at iucr.org is unavailable due to technical difficulties.
Osteoporosis Decision Aid Osteoporosis Decision Aid | Mayo Clinic Shared Decision Making National Resource Center Toggle navigation Osteoporosis Decision Aid The Osteoporosis Choice decision aid conveys the pros and cons of treatment It uses estimates of the patient's based on the FRAX calculator. Decision aids to be used during the encounter: interactive tool Printed version Decision aids in practice: Additional resources DISCLAIMER : No decision aid replaces the conversation patients should
Management of osteoporosis and the prevention of fragility fractures SIGN 142 • Management of osteoporosis and the prevention of fragility fractures A national clinical guideline March 2015 EvidenceKEY TO EVIDENCE STATEMENTS AND RECOMMENDATIONS LEVELS OF EVIDENCE 1 ++ High-quality meta-analyses, systematic reviews of RCTs, or RCTs with a very low risk of bias 1 + Well-conducted meta-analyses, systematic reviews, or RCTs with a low risk of bias 1 - Meta-analyses, systematic reviews, or RCTs (...) is the definitive version at all times. This version can be found on our web site www.sign.ac.uk. This document is produced from elemental chlorine-free material and is sourced from sustainable forests.Scottish Intercollegiate Guidelines Network Management of osteoporosis and the prevention of fragility fractures A national clinical guideline March 2015Scottish Intercollegiate Guidelines Network Gyle Square, 1 South Gyle Crescent Edinburgh EH12 9EB www.sign.ac.uk First published March 2015 ISBN 978 1 909103 35
High-Protein Diet Without Increased Calcium Intake Can Lead to Ridge Resorption and Osteoporosis in Women UTCAT2893, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title High-Protein Diet Without Increased Calcium Intake Can Lead to Ridge Resorption and Osteoporosis in Women Clinical Question How does a high protein diet affect ridge resorption in women? Clinical Bottom Line A high protein diet coupled with a low calcium (...) intake can increase urinary losses of calcium and is linked to osteoporosis and ridge resorption in older women. This is supported by narrative reviews outlining observations of populations who maintain a high protein diet and a narrative review of studies showing the relationship between increased protein intake and increased levels of calcium lost in urine. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence
Repeat Dual Energy X-Ray Absorptiometry Intervals in Osteoporosis Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses should be considered (...) in Osteoporosis: Clinical Effectiveness and Guidelines DATE: 04 March 2015 RESEARCH QUESTIONS 1. What are the clinical benefits and harms of repeat dual energy x-ray absorptiometry (DEXA) scans every two years in patients with osteoporosis or at risk for osteoporosis? 2. What are the evidence-based guidelines for DEXA in patients with osteoporosis or at risk for osteoporosis? KEY FINDINGS Two health technology assessments, one observational study, and eight evidence-based guidelines were identified regarding
Management of Osteoporosis Malaysian Osteoporosis Society Clinical Guidance on Management of Osteoporosis 2 0 12 Academy of Medicine Ministry of Health Malaysia MOH/P/PAK/345.17(GU) Second Edition (2015) 02 Published by: Malaysian Osteoporosis Society c/o No. 79, Jalan SS 23/15 Taman SEA, 47400 Petaling Jaya Selangor Darul Ehsan, Malaysia Endorsed by: Malaysia Health Technology Assessment Section (MaHTAS) Medical Development Division, Ministry of Health Malaysia Level 4, Block E1, Precinct 1 (...) Federal Government Administrative Centre 62590, Putrajaya, Malaysia Copyright The copyright owner of this publication is the Malaysia Osteoporosis Society (persatuan Osteoporosis Malaysia). Content may be reproduced in any number of copies and in any format or medium provided that a copyright acknowledgement to the Malaysia Osteoporosis Society is included and the content is not changed, not sold, nor used to promote or endorse any product or service, and not used in an inappropriate or misleading
Abaloparatide for postmenopausal osteoporosis ? first and second line Abaloparatide for postmenopausal osteoporosis – first and second line Abaloparatide for postmenopausal osteoporosis – first and second line NIHR HSC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSC. Abaloparatide for postmenopausal osteoporosis – first (...) and second line. Birmingham: NIHR Horizon Scanning Centre (NIHR HSC). Horizon Scanning Review. 2014 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Humans; Osteoporosis, Postmenopausal Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence NIHR Horizon Scanning Centre, School of Health&Population Sciences, University of Birmingham, Public Health building, Edgbaston, Birmingham, B15 2TT
Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm Comparative cost-effectiveness of bazedoxifene and raloxifene in the treatment of postmenopausal osteoporosis in Europe, using the FRAX algorithm Kim K, Svedbom A, Luo X, Sutradhar S, Kanis JA Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study evaluated the cost-effectiveness of raloxifene and bazedoxifene for postmenopausal women with osteoporosis, based on their fracture probability, in eight European countries. The authors concluded
Prevalence and clinical prediction of osteoporosis in a contemporary cohort of patients with rheumatoid arthritis Osteoporosis has previously been reported to be twice as common in patients with RA as in controls, but these studies predate the introduction of aggressive management of RA. The aim of this study was to evaluate the prevalence and clinical predictors of osteoporosis in RA in a contemporary cohort and to develop a clinical tool for the identification of patients at risk.The (...) prevalence of osteoporosis was related to clinical and demographic variables in 304 consecutive RA patients undergoing DXA at a single centre between 2009 and 2010 and compared with the frequency of osteoporosis in a population-based cohort of 903 subjects.The RA cohort was predominantly female (81.9%), with an average age of 63.5 years (s.d. 11.8) and a disease duration of 9.6 years (s.d. 10.2). Osteoporosis was present in 91 (29.9%) patients at either the spine or total hip compared with 157/903 (17.4
Denosumab for glucocorticoid-induced osteoporosis Denosumab for glucocorticoid-induced osteoporosis Denosumab for glucocorticoid-induced osteoporosis NIHR HSC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSC. Denosumab for glucocorticoid-induced osteoporosis. Birmingham: NIHR Horizon Scanning Centre (NIHR HSC). Horizon Scanning (...) Review. 2014 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Diphosphonatess; Osteoporosis Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health&Population Sciences, University of Birmingham, 90 Vincent
FRAX without Bone Mineral Density Versus Osteoporosis Self-Assessment Screening Tool as Predictors of Osteoporosis in Primary Screening of Individuals Aged 70 and Older To compare two well-validated tools--the FRAX without bone mineral density (BMD) and the Osteoporosis Self-Assessment Screening Tool (OST)--in predicting osteoporosis and to define thresholds above and below which it would be reasonable to recommend omitting BMD testing.Retrospective review.General practices in Western (...) Australia.Individuals aged 70 and older responding to a prospective audit of osteoporosis investigation and management for whom dual-energy X-ray absorptiometry scan results and clinical risk factor data were available (N = 626).Receiver operating characteristic (ROC) curves were compared, upper and lower thresholds for omission of screening BMD were proposed, and the statistical performance measures for the tests are reported.The areas under the ROC curves for the OST (0.76-0.82) were slightly better than for FRAX
Osteoporosis Has No Significant Impact On Dental Implant Osseointegration UTCAT2645, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Osteoporosis Has No Significant Impact On Dental Implant Osseointegration Clinical Question Does osteoporosis affect the success rates of osseointegration of dental implants in adult patients? Clinical Bottom Line Adult patient with osteoporosis show no significant increase in dental (...) implant osseointegration failures as compared to adults without osteoporosis. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Chen/2013 1142 human adults Meta-Analysis Key results The meta-analysis reports a lack of impact of osteoporosis on the failures of dental implant. There was a direct influence of a patients osteoporosis on the outcome of dental implants, but it was not significant (n = 4; RR
Bisphosphonates for osteoporosis in people with cystic fibrosis. Osteoporosis is a bone mineralisation disorder occurring in about one third of adults with cystic fibrosis. Bisphosphonates can increase bone mineral density and decrease the risk of new fractures in post-menopausal women and people receiving long-term oral corticosteroids.To assess the effects of bisphosphonates on the frequency of fractures, bone mineral density, quality of life, adverse events, trial withdrawals, and survival
Chinese herbal medicines for treating osteoporosis. Chinese herbal medicines have been used for a long time to treat osteoporosis. The evidence of their benefits and harms needs to be systematically reviewed.To assess the beneficial and harmful effects of Chinese herbal medicines as a general experimental intervention for treating primary osteoporosis by comparing herbal treatments with placebo, no intervention and conventional medicine.We searched the following electronic databases to January
Systematic review of the use of bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high-risk groups Systematic review of the use of bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high-risk groups Journals Library An error occurred retrieving content to display, please try again
Portable bone mineral density scanners for screening and diagnosis of osteoporosis: uses, limitations, and guidelines Portable bone mineral density scanners for screening and diagnosis of osteoporosis: uses, limitations, and guidelines Portable bone mineral density scanners for screening and diagnosis of osteoporosis: uses, limitations, and guidelines CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation (...) of the quality of this assessment has been made for the HTA database. Citation CADTH. Portable bone mineral density scanners for screening and diagnosis of osteoporosis: uses, limitations, and guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response - Summary of Abstracts. 2013 Authors' conclusions Three non-randomized studies were identified regarding the uses and limitations of portable bone mineral density (BMD) scanners for screening and diagnosis of osteoporosis