Latest & greatest articles for pain

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Top results for pain

4141. A cost-utility study of the use of pregabalin in treatment-refractory neuropathic pain

A cost-utility study of the use of pregabalin in treatment-refractory neuropathic pain A cost-utility study of the use of pregabalin in treatment-refractory neuropathic pain A cost-utility study of the use of pregabalin in treatment-refractory neuropathic pain Gordon J, Lister S, Prettyjohns M, McEwan P, Tetlow A, Gabriel Z Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to assess the cost-effectiveness of pregabalin for patients with refractory neuropathic pain. The authors concluded that it was a cost-effective alternative to usual care. On the whole, the methods were well reported and the authors' conclusions seem valid for pregabalin in addition to usual care, rather than as an alternative. Type of economic

2012 NHS Economic Evaluation Database.

4142. H-FABP immunoturbimetric assay with troponin testing for the assessment of heart-related chest pain

H-FABP immunoturbimetric assay with troponin testing for the assessment of heart-related chest pain H-FABP immunoturbimetric assay with troponin testing for the assessment of heart-related chest pain H-FABP immunoturbimetric assay with troponin testing for the assessment of heart-related chest pain NIHR HSC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA (...) database. Citation NIHR HSC. H-FABP immunoturbimetric assay with troponin testing for the assessment of heart-related chest pain. Birmingham: NIHR Horizon Scanning Centre (NIHR HSC). Horizon Scanning Review. 2012 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Chest Pains; Fatty Acid-Binding Proteins; Hematologic Tests; Troponin Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence

2012 Health Technology Assessment (HTA) Database.

4143. Lubiprostone (Amitiza) for opioid-induced constipation in patients with chronic non-cancer pain

Lubiprostone (Amitiza) for opioid-induced constipation in patients with chronic non-cancer pain Lubiprostone (Amitiza) for opioid-induced constipation in patients with chronic non-cancer pain Lubiprostone (Amitiza) for opioid-induced constipation in patients with chronic non-cancer pain NIHR HSC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database (...) . Citation NIHR HSC. Lubiprostone (Amitiza) for opioid-induced constipation in patients with chronic non-cancer pain. Birmingham: NIHR Horizon Scanning Centre (NIHR HSC). Horizon Scanning Review. 2012 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Alprostadils; Chronic Pain; Constipation Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence The NIHR Horizon Scanning Centre, Department

2012 Health Technology Assessment (HTA) Database.

4144. Watchful dosing of morphine or morphine equivalent dosing in the treatment of chronic non-cancer pain: a review of the clinical evidence

Watchful dosing of morphine or morphine equivalent dosing in the treatment of chronic non-cancer pain: a review of the clinical evidence Watchful dosing of morphine or morphine equivalent dosing in the treatment of chronic non-cancer pain: a review of the clinical evidence Watchful dosing of morphine or morphine equivalent dosing in the treatment of chronic non-cancer pain: a review of the clinical evidence CADTH Record Status This is a bibliographic record of a published health technology (...) assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Watchful dosing of morphine or morphine equivalent dosing in the treatment of chronic non-cancer pain: a review of the clinical evidence. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2012 Authors' conclusions The evidence base around a watchful dose threshold for morphine or equivalent opioid dosing was limited in both quality and quantity

2012 Health Technology Assessment (HTA) Database.

4145. Opioid trial periods for management of chronic non-cancer pain: a review of clinical effectiveness, guidelines and recommendations

Opioid trial periods for management of chronic non-cancer pain: a review of clinical effectiveness, guidelines and recommendations Opioid trial periods for management of chronic non-cancer pain: a review of clinical effectiveness, guidelines and recommendations Opioid trial periods for management of chronic non-cancer pain: a review of clinical effectiveness, guidelines and recommendations CADTH Record Status This is a bibliographic record of a published health technology assessment from (...) a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Opioid trial periods for management of chronic non-cancer pain: a review of clinical effectiveness, guidelines and recommendations. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2012 Authors' conclusions One non-randomized study and two guidelines suggest that opioid trial periods may be effective in managing chronic non-cancer pain. When conducting a trial

2012 Health Technology Assessment (HTA) Database.

4146. Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety

Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety Codeine and acetaminophen for pain relief: a review of the clinical efficacy and safety CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation CADTH. Codeine (...) and acetaminophen for pain relief: a review of the clinical efficacy and safety. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2012 Authors' conclusions Based on this review, both codeine and acetaminophen/codeine provide better chronic pain relief than placebo. Chronic use of acetaminophen at doses higher than 2000 mg per day may be associated with increased risk of gastrointestinal events, liver toxicity, and renal dysfunction or failure. This review found evidence of increased risk

2012 Health Technology Assessment (HTA) Database.

4147. Noncyclic chronic pelvic pain therapies for women: comparative effectiveness

Noncyclic chronic pelvic pain therapies for women: comparative effectiveness Noncyclic chronic pelvic pain therapies for women: comparative effectiveness Noncyclic chronic pelvic pain therapies for women: comparative effectiveness Andrews J, Yunker A, Reynolds WS, Likis FE, Sathe NA, Jerome RN Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database (...) . Citation Andrews J, Yunker A, Reynolds WS, Likis FE, Sathe NA, Jerome RN. Noncyclic chronic pelvic pain therapies for women: comparative effectiveness. Rockville: Agency for Healthcare Research and Quality (AHRQ). Comparative Effectiveness Review No. 41. 2012 Authors' objectives The Vanderbilt Evidence-based Practice Center systematically reviewed evidence on therapies for women age 18 and over with noncyclic chronic pelvic pain (CPP). We focused on the prevalence of conditions thought to occur

2012 Health Technology Assessment (HTA) Database.

4148. Treatment of functional chest pain with antidepressants: a meta-analysis

Treatment of functional chest pain with antidepressants: a meta-analysis Treatment of functional chest pain with antidepressants: a meta-analysis Treatment of functional chest pain with antidepressants: a meta-analysis Wang W, Sun YH, Wang YY, Wang YT, Wang W, Li YQ, Wu SX CRD summary This review concluded that antidepressant medications were associated with improvements in pain and psychological symptoms in patients with functional chest pain, but there may be an increase in side-effects (...) . The review had some data limitations and there was evidence of statistical variation, which means that the evidence may not be reliable and the authors' conclusions should be interpreted cautiously. Authors' objectives To investigate the efficacy of antidepressant treatments for functional chest pain. Searching MEDLINE, PsycINFO, Scopus and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched to July 2011, with no language restrictions. Search terms were reported. Reference lists

2012 DARE.

4149. Acupuncture for chronic pain: individual patient data meta-analysis

Acupuncture for chronic pain: individual patient data meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

4150. Accuracy of single progesterone test to predict early pregnancy outcome in women with pain or bleeding: meta-analysis of cohort studies

Accuracy of single progesterone test to predict early pregnancy outcome in women with pain or bleeding: meta-analysis of cohort studies Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

4151. A systematic review of interventions for reducing pain and distress in children undergoing voiding cystourethrography

A systematic review of interventions for reducing pain and distress in children undergoing voiding cystourethrography Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

4152. Short-term effects of kinesio taping versus cervical thrust manipulation in patients with mechanical neck pain: a randomized clinical trial Full Text available with Trip Pro

Short-term effects of kinesio taping versus cervical thrust manipulation in patients with mechanical neck pain: a randomized clinical trial Randomized clinical trial.To compare the effectiveness of cervical spine thrust manipulation to that of Kinesio Taping applied to the neck in individuals with mechanical neck pain, using self-reported pain and disability and cervical range of motion as measures.The effectiveness of cervical manipulation has received considerable attention in the literature (...) . However, because some patients cannot tolerate cervical thrust manipulation, alternative therapeutic options should be investigated.Eighty patients (36 women) were randomly assigned to 1 of 2 groups: the manipulation group, which received 2 cervical thrust manipulations, and the tape group, which received Kinesio Taping applied to the neck. Neck pain (11-point numeric pain rating scale), disability (Neck Disability Index), and cervical-range-of-motion data were collected at baseline and 1 week after

2012 EvidenceUpdates Controlled trial quality: uncertain

4153. Topical capsaicin (low concentration) for chronic neuropathic pain in adults. Full Text available with Trip Pro

Topical capsaicin (low concentration) for chronic neuropathic pain in adults. Topical creams with capsaicin are used to treat pain from a wide range of chronic conditions including neuropathic pain. Following application to the skin capsaicin causes enhanced sensitivity to noxious stimuli, followed by a period with reduced sensitivity and, after repeated applications, persistent desensitisation. There is uncertainty about the efficacy and tolerability of capsaicin for treating painful chronic (...) neuropathies. This is an update of an earlier review of topical capsaicin for chronic neuropathic pain in adults that looked at all doses and formulations of capsaicin. The original review has now been split: here we consider only formulations using a low concentration of capsaicin (< 1%) applied several times daily over several weeks, while another review will consider a single application of capsaicin at a high concentration.To review the evidence from controlled trials on the efficacy and tolerability

2012 Cochrane

4154. Home-based cervical traction for treatment of neck pain

Home-based cervical traction for treatment of neck pain Home-based cervical traction for treatment of neck pain Home-based cervical traction for treatment of neck pain Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Home-based cervical traction for treatment of neck pain. Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2012 Authors' conclusions (...) Neck pain is a frequently reported musculoskeletal complaint, which can be disabling and costly to society. Approximately one-third of the general population will experience neck pain at some point; of those, 14% will have symptoms lasting longer than 6 months. Possible causes include compression of neural structures resulting in spasm and radiculopathy; inflammatory, neoplastic, infectious, or degenerative processes; or disruption of tissue secondary to trauma. Many treatment options for neck pain

2012 Health Technology Assessment (HTA) Database.

4155. Outpatient cervical traction for treatment of neck pain

Outpatient cervical traction for treatment of neck pain Outpatient cervical traction for treatment of neck pain Outpatient cervical traction for treatment of neck pain Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Outpatient cervical traction for treatment of neck pain. Lansdale: HAYES, Inc.. Healthcare Technology Brief Publication. 2012 Authors' conclusions (...) Neck pain is a frequently reported musculoskeletal complaint, which can be disabling and costly to society. Approximately one-third of the general population will experience neck pain at some point; of those, 14% will have symptoms lasting longer than 6 months. Possible causes include compression of neural structures resulting in spasm and radiculopathy; inflammatory, neoplastic, infectious, or degenerative processes; or disruption of tissue secondary to trauma. Many treatment options for neck pain

2012 Health Technology Assessment (HTA) Database.

4156. Do educational interventions improve cancer patients` quality of life and reduce pain intensity? Quantitative systematic review (Abstract)

Do educational interventions improve cancer patients` quality of life and reduce pain intensity? Quantitative systematic review This paper reports a quantitative systematic review of the effects of educational interventions on quality of life, pain intensity and pain interference in cancer patients.Cancer pain has a marked negative impact on quality of life, and this has become an important issue in discussions of treatment options. Patient education seems to be effective in pain management (...) , but no review has been published with quality of life as an outcome measure.Relevant publications from 2000 to 2010 were identified in six databases (Medline, CIHAHL, PubMed, EMBASE, PsycINFO and DARE) and by means of hand-searches. All randomized controlled trial studies of pain-education programmes for cancer patients were considered, and a quantitative review of effectiveness carried out.Studies were critically appraised by three independent reviewers, and the Jadad score was used to assess the quality

2012 EvidenceUpdates

4157. Intravenous Ketorolac versus Intravenous Opiates for the Management of Acute Pain in the Emergency Department: Safety

Intravenous Ketorolac versus Intravenous Opiates for the Management of Acute Pain in the Emergency Department: Safety Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within (...) versus Intravenous Opiates for the Management of Acute Pain in the Emergency Department: Safety DATE: 17 July 2012 RESEARCH QUESTION What is the clinical evidence regarding the comparative safety of intravenous ketorolac versus intravenous opiate analgesics for the management of acute pain in adult patients in the emergency department? KEY MESSAGE One randomized controlled trial was identified regarding regarding the comparative safety of intravenous ketorolac versus intravenous opiate analgesics

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

4158. Urgent C-Reactive Protein or Erythrocyte Sedimentation Rate Testing for the Identification of Pediatric Pain: Clinical Evidence and Guidelines

Urgent C-Reactive Protein or Erythrocyte Sedimentation Rate Testing for the Identification of Pediatric Pain: Clinical Evidence and Guidelines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all (...) and conditions. TITLE: Urgent C-Reactive Protein or Erythrocyte Sedimentation Rate Testing for the Identification of Pediatric Pain: Clinical Evidence and Guidelines DATE: 17 July 2012 RESEARCH QUESTIONS 1. What is the evidence supporting the use of urgent c-reactive protein testing for the identification of pain and subsequent pain management in pediatric patients with suspected pain? 2. What is the evidence supporting the use of urgent erythrocyte sedimentation rate testing for the identification of pain

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

4159. Perioperative Intravenous Lidocaine Decreases the Incidence of Persistent Pain After Breast Surgery (Abstract)

Perioperative Intravenous Lidocaine Decreases the Incidence of Persistent Pain After Breast Surgery Breast cancer surgery is associated with a high incidence of persistent postsurgical pain (PPSP). The aim of this study was to evaluate the impact of intravenous (IV) lidocaine on acute and PPSP, analgesic requirements, and sensation abnormalities in patients undergoing surgery for breast cancer.Thirty-six patients participated in this randomized, double-blinded study. Before induction of general (...) anesthesia, patients received a bolus of intravenous lidocaine 1.5 mg/kg followed by a continuous infusion of lidocaine 1.5 mg/kgh (lidocaine group) or an equal volume of saline (control group). The infusion was stopped 1 hour after the skin closure. Pain scores and analgesic consumption were recorded at 2, 4, 24 hours, and then daily for 1 week postoperatively. Three months later, patients were assessed for PPSP and secondary hyperalgesia.Two (11.8%) patients in the lidocaine group and 9 (47.4

2012 EvidenceUpdates Controlled trial quality: uncertain

4160. Transcranial direct current stimulation for the reduction of clinical and experimentally induced pain: a systematic review and meta-analysis (Abstract)

Transcranial direct current stimulation for the reduction of clinical and experimentally induced pain: a systematic review and meta-analysis To evaluate the effectiveness of transcranial direct current stimulation on clinical and experimental pain, and to identify the most beneficial stimulation parameters.Predefined search using key terms of information sources including: MEDLINE, EMBASE, CAB Abstracts, and PsychINFO, Cochrane Register of Controlled Trials, CINAHL, and PeDRO databases (...) ; reference lists of retrieved articles, journal contents, and conference proceedings. Two reviewers independently searched and evaluated publications. English and non-English controlled trials that applied direct current stimulation to the brain published before September 30, 2010 were included. Studies using magnetic stimulation or pulsed currents were excluded.Trials investigating experimental pain in healthy participants (n=6) used a wide variety of stimulation and outcome parameters that did

2012 EvidenceUpdates