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Latest & greatest articles for pneumonia
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pneumonia or other clinical topics then use Trip today.
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Antibiotic preferences for childhood pneumonia vary by physician type and European region Survey of EAPRASnet and @PREPARE_EUROPE members reveals heterogeneity of antibiotic choice for childhood pneumonia http://ow.ly/4mIS2P.
The Intensive Care Society recommended bundle of interventions for the prevention of ventilator-associated pneumonia Ventilator-associated pneumonia is an important healthcare-associated infection. Interventions for the prevention of ventilator-associated pneumonia are often used within bundles of care. Recent evidence has challenged widespread practices mandating a review of subject. This article outlines guidance for ventilator-associated pneumonia prevention.
Responses to Bacteria, Virus, and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia Plasma-detectable biomarkers that rapidly and accurately diagnose bacterial infections in children with suspected pneumonia could reduce the morbidity of respiratory disease and decrease the unnecessary use of antibiotic therapy.Using 56 markers measured in a multiplexed immunoassay, we sought to identify proteins and protein combinations that could discriminate bacterial from viral or malarial (...) diagnoses.We selected 80 patients with clinically diagnosed pneumonia (as defined by the World Health Organization) who also met criteria for bacterial, viral, or malarial infection based on clinical, radiographic, and laboratory results. Ten healthy community control subjects were enrolled to assess marker reliability. Patients were subdivided into two sets: one for identifying potential markers and another for validating them.Three proteins (haptoglobin, tumor necrosis factor receptor 2 or IL-10
CURB-65 Performance among Admitted and Discharged Emergency Department Patients with Community Acquired PneumoniaPneumonia severity tools were primarily developed in cohorts of hospitalized patients, limiting their applicability to the emergency department (ED). We describe current community ED admission practices and examine the accuracy of the CURB-65 to predict 30-day mortality for patients, either discharged or admitted with community-acquired pneumonia (CAP).A retrospective, observational
Prevalence and Risk Factors associated with Extended Spectrum Beta Lactamase Producing Escherichia coli and Klebsiella pneumoniae Isolates in Hospitalized Patients in Kashan (Iran) Production of extended spectrum beta lactamase (ESBL) is an important mechanism of antimicrobial resistance in Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) isolates. This study was performed to determine the prevalence and risk factors associated with ESBL producing strains of E. coli and K (...) . pneumoniae.In this cross-sectional study, 250 strains (134 E. coli and 116 K. pneumoniae) were obtained, and ESBL producing isolates were detected by the combination disk test in Shahid Beheshti Hospital in Kashan, Iran, from February 2012 to June 2013. Antimicrobial resistance was screened by the disk diffusion method and was confirmed by E-test. Furthermore, risk factors of ESBL producing E. coli and K. pneumoniae microorganisms were determined. Data were analyzed by SPSS version 16, using descriptive
Intensive Care Unit Admission and Mortality Among Medicare Beneficiaries With Pneumonia--Reply 27002455 2016 03 24 2018 12 02 1538-3598 315 12 2016 Mar 22-29 JAMA JAMA Intensive Care Unit Admission and Mortality Among Medicare Beneficiaries With Pneumonia--Reply. 1285 10.1001/jama.2015.18032 Valley Thomas S TS Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor. Ryan Andrew M AM Center for Health Outcomes and Policy, University of Michigan, Ann Arbor. Cooke Colin (...) R CR Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor. eng K08 HS020672 HS AHRQ HHS United States Letter Comment United States JAMA 7501160 0098-7484 AIM IM JAMA. 2015 Sep 22-29;314(12):1272-9 26393850 JAMA. 2016 Mar 22-29;315(12):1284-5 27002453 Female Hospital Mortality Hospitalization statistics & numerical data Humans Intensive Care Units statistics & numerical data Male Pneumonia mortality 2016 3 23 6 0 2016 3 24 6 0 2016 3 25 6 0 ppublish 27002455 2504804
Antibiotic Therapy for Adults Hospitalized With Community-Acquired Pneumonia: A Systematic Review. Antibiotic therapy is the cornerstone of medical management for community-acquired pneumonia.To assess the associations between 3 key aspects of antibiotic therapy (optimal time to antibiotic initiation, initial antibiotic selection, and criteria for the transition from intravenous to oral therapy) and short-term mortality in adults hospitalized with community-acquired pneumonia.Bibliographic (...) databases of MEDLINE, EMBASE, and the Cochrane Collaboration were searched for studies of adults hospitalized with radiographically confirmed community-acquired pneumonia published from January 1, 1995, until November 5, 2015.Twenty studies (17 observational and 3 randomized trials) met eligibility criteria. Among 8 observational studies identified, the 4 largest (study populations of 2878 to 1,170,022) found that antibiotic initiation within 4 to 8 hours of hospital arrival was associated with relative
Association of Admission to Veterans Affairs Hospitals vs Non-Veterans Affairs Hospitals With Mortality and Readmission Rates Among Older Men Hospitalized With Acute Myocardial Infarction, Heart Failure, or Pneumonia. Little contemporary information is available about comparative performance between Veterans Affairs (VA) and non-VA hospitals, particularly related to mortality and readmission rates, 2 important outcomes of care.To assess and compare mortality and readmission rates among men (...) in VA and non-VA hospitals.Cross-sectional analysis involving male Medicare fee-for-service beneficiaries aged 65 years or older hospitalized between 2010 and 2013 in VA and non-VA acute care hospitals for acute myocardial infarction (AMI), heart failure (HF), or pneumonia using the Medicare Standard Analytic Files and Enrollment Database together with VA administrative claims data. To avoid confounding geographic effects with health care system effects, we studied VA and non-VA hospitals within
[Effectiveness of the outpatient treatment of the community-acquired pneumonia: systematic review and meta-analysis]. Community-acquired pneumonia is an important cause of mortality and morbidity worldwide. Therefore, our aim was to assess the efficacy and safety of outpatient treatment of community-acquired pneumonia.We systematically reviewed randomized clinical trials evaluating efficacy and safety of outpatient treatment (OPT) compared with inpatient treatment (IPT) of community-acquired (...) pneumonia in patients without added co-morbidity. Relative Risk (RR) and 95 % confidence interval (95 % CI) were calculated.From 4088 reviewed articles, two articles were included for meta-analysis, including 2324 patients. One study was conducted in adults, and the other was carried out in pediatric patients. Treatment setting was not significantly associated with treatment failure (RR 0.84 [95% CI 0.68, 1.02]). Death occurred in 6 of 2324 with no difference between the two groups (RR 0.56 [95 % CI
Semi-recumbent position versus supine position for the prevention of ventilator-associated pneumonia in adults requiring mechanical ventilation. Ventilator-associated pneumonia (VAP) is associated with increased mortality, prolonged length of hospital stay and increased healthcare costs in critically ill patients. Guidelines recommend a semi-recumbent position (30º to 45º) for preventing VAP among patients requiring mechanical ventilation. However, due to methodological limitations in existing (...) systematic reviews, uncertainty remains regarding the benefits and harms of the semi-recumbent position for preventing VAP.To assess the effectiveness and safety of semi-recumbent positioning versus supine positioning to prevent ventilator-associated pneumonia (VAP) in adults requiring mechanical ventilation.We searched CENTRAL (2015, Issue 10), which includes the Cochrane Acute Respiratory Infections Group's Specialised Register, MEDLINE (1946 to October 2015), EMBASE (2010 to October 2015), CINAHL
Do Corticosteroids Provide Benefit to Patients With Community-Acquired Pneumonia? TAKE-HOME MESSAGE For adult patients with community-acquired pneumonia requiring hospitalization, datasuggestthatcorticosteroid therapy mayreduce mortality, needformechanical ventilation, and hospital length of stay. Do Corticosteroids Provide Bene?t to Patients With Community-Acquired Pneumonia? EBEM Commentators Michael Gottlieb, MD John Bailitz, MD Department of Emergency Medicine Cook County Hospital Chicago (...) syndrome, and decreased hospital length of stay. There was no statistically signi?cant differ- ence in mortality or admission to the ICU. There was an increased incidence of hyperglycemia asso- ciated with steroid use but no Table. Comparison of corticosteroids to control for community-acquired pneumonia. Number of Studies (TotalParticipants) Relative Risk (95% CI) MeanDifference (95% CI) Heterogeneity I 2 ,% All-cause mortality 12 (1,974) 0.7 (0.4 to 1.0) 6 Need for mechanical ventilation 5 (1,060
Use of Gentamicin as Empiric Coverage for Ventilator-Associated Pneumonia: The ?Con? Perspective Use of Gentamicin as Empiric Coverage for Ventilator-Associated Pneumonia: The “Con” Perspective | Surgical Infections Login to your account Username Password (...) If the address matches an existing account you will receive an email with instructions to retrieve your username Quick Search in Journals Enter words / phrases / DOI / ISBN / keywords / authors / etc Search Quick Search anywhere Enter words / phrases / DOI / ISBN / keywords / authors / etc Search Quick search in Citations Journal Year Volume Issue Page Search Point-Counterpoint: Aminoglycosides and Ventilator-Associate Pneumonia and Mercy Northwest Arkansas Hospital, Rogers, Arkansas. and St. Catherine's
An Argument for the Use of Aminoglycosides in the Empiric Treatment of Ventilator-Associated Pneumonia An Argument for the Use of Aminoglycosides in the Empiric Treatment of Ventilator-Associated Pneumonia | Surgical Infections Login to your account Username (...) Email If the address matches an existing account you will receive an email with instructions to retrieve your username Quick Search in Journals Enter words / phrases / DOI / ISBN / keywords / authors / etc Search Quick Search anywhere Enter words / phrases / DOI / ISBN / keywords / authors / etc Search Quick search in Citations Journal Year Volume Issue Page Search Point-Counterpoint: Aminoglycosides and Ventilator-Associate Pneumonia Published Online: 20 May 2016 Abstract Background: Appropriate
Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: Official ATS/IDSA Clinical Practice Guidelines Clinical Infectious Diseases IDSA GUIDELINE Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society AndreC.Kalil, 1,a MarkL.Metersky, 2,a MichaelKlompas, 3,4 JohnMuscedere, 5 DanielA.Sweeney, 6 LucyB.Palmer, 7 LenaM.Napolitano, 8 (...) for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient’s individual circumstances. These guidelines are intended for use by healthcare professionals who care for patients at risk for hospital-acquired pneumonia (HAP
Best practices for preventing aspiration pneumonia in hospital patients Best practices for preventing aspiration pneumonia in hospital patients Best practices for preventing aspiration pneumonia in hospital patients Mitchell, MD, Coniglio, MS, Posencheg, MA, Umscheid, CA Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell, MD (...) , Coniglio, MS, Posencheg, MA, Umscheid, CA. Best practices for preventing aspiration pneumonia in hospital patients. Philadelphia: Center for Evidence-based Practice (CEP). 2016 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Humans; Inpatients; Pneumonia, Aspiration Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania
Diagnosis and Management of Nursing Home Acquired Pneumonia (NHAP) DIAGNOSIS AND MANAGEMENT OF NURSING HOME ACQUIRED PNEUMONIA (NHAP) Clinical Practice Guideline | March 2015 These recommendations are systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances. They should be used as an adjunct to sound clinical decision making. OBJECTIVE In caring for residents in long term care facilities (LTCF) Alberta (...) clinicians will: ? Increase the accuracy of clinical diagnosis of NHAP ? Initiate timely treatment for NHAP ? Optimize use of laboratory and diagnostic imaging services in the diagnosis of NHAP ? Optimize use of antibiotics in the treatment of NHAP ? Ensure practices to prevent respiratory infections are in place in the LTCF ? Facilitate teamwork and communication in the evaluation and management of residents with NHAP TARGET POPULATION Patients with pneumonia acquired in a LTCF LTCF is any congregate
Nebulised colistin for ventilator-associated pneumonia prevention We evaluated whether prophylactic nebulised colistin could reduce ventilator-associated pneumonia (VAP) rates in an intensive care unit (ICU) setting with prevalent multidrug-resistant (MDR) bacteria.We used a single-centre, two-arm, randomised, open-label, controlled trial in a 12-bed ICU in the University Hospital of Larissa, Greece. Patient inclusion criteria included mechanical ventilation of >48 h. The two arms consisted
Community-Acquired Pneumonia Requiring Hospitalization. 26650159 2015 12 30 2018 12 02 1533-4406 373 24 2015 12 10 The New England journal of medicine N. Engl. J. Med. Community-Acquired Pneumonia Requiring Hospitalization. 2382 10.1056/NEJMc1511751 Jain Seema S Self Wesley H WH Wunderink Richard G RG CDC EPIC Study Team eng Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2015 Jul 30;373(5):415-27 26172429 N Engl J Med. 2015 Dec 10;373(24):2380 26650160 N Engl J (...) Med. 2015 Dec 10;373(24):2381 26650162 N Engl J Med. 2015 Dec 10;373(24):2381 26650163 N Engl J Med. 2015 Dec 10;373(24):2380-1 26650161 Female Hospitalization statistics & numerical data Humans Male Pneumonia epidemiology 2015 12 10 6 0 2015 12 10 6 0 2015 12 31 6 0 ppublish 26650159 10.1056/NEJMc1511751 10.1056/NEJMc1511751#SA5