Latest & greatest articles for pregnancy

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Top results for pregnancy

1. Regimens of vitamin D supplementation for women during pregnancy. (PubMed)

Regimens of vitamin D supplementation for women during pregnancy. Vitamin D deficiency during pregnancy increases the risk of pre-eclampsia, gestational diabetes, preterm birth, and low birthweight. In a previous Cochrane Review we found that supplementing pregnant women with vitamin D alone compared to no vitamin D supplementation may reduce the risk of pre-eclampsia, gestational diabetes, and low birthweight and may increase the risk of preterm births if it is combined with calcium. However (...) the effects of different vitamin D regimens are not yet clear.To assess the effects and safety of different regimens of vitamin D supplementation alone or in combination with calcium or other vitamins, minerals or nutrients during pregnancy, specifically doses of 601 international units per day (IU/d) or more versus 600 IU/d or less; and 4000 IU/d or more versus 3999 IU/d or less.We searched the Cochrane Pregnancy and Childbirth's Trials Register, ClinicalTrials.gov, the WHO International Clinical Trials

2019 Cochrane

2. Buprenorphine for Opioid Use Disorders during Pregnancy: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines

Buprenorphine for Opioid Use Disorders during Pregnancy: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines Buprenorphine for Opioid Use Disorders during Pregnancy: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Buprenorphine for Opioid Use Disorders during Pregnancy: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines Buprenorphine (...) for Opioid Use Disorders during Pregnancy: A Review of Comparative Clinical Effectiveness, Safety, Cost-Effectiveness, and Guidelines Last updated: May 9, 2019 Project Number: RC1111-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the comparative clinical effectiveness of various buprenorphine or buprenorphine-naloxone formulations versus other buprenorphine formulations for the treatment of opioid use disorders during pregnancy

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

3. Withdrawal Management and Treatment of Crystal Methamphetamine Addiction in Pregnancy: A Review of Clinical Effectiveness and Guidelines

Withdrawal Management and Treatment of Crystal Methamphetamine Addiction in Pregnancy: A Review of Clinical Effectiveness and Guidelines Withdrawal Management and Treatment of Crystal Methamphetamine Addiction in Pregnancy: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Withdrawal Management and Treatment of Crystal Methamphetamine Addiction in Pregnancy: A Review of Clinical Effectiveness and Guidelines Withdrawal Management and Treatment of Crystal (...) Methamphetamine Addiction in Pregnancy: A Review of Clinical Effectiveness and Guidelines Last updated: June 17, 2019 Project Number: RC1130-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of interventions for the withdrawal management or treatment of persons who are pregnant and addicted to crystal methamphetamine? What are the evidence-based guidelines regarding withdrawal management

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

4. Pregnancy Testing for Patients Requiring Diagnostic Imaging or Surgery in the Emergency Department: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Pregnancy Testing for Patients Requiring Diagnostic Imaging or Surgery in the Emergency Department: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Pregnancy Testing for Patients Requiring Diagnostic Imaging or Surgery in the Emergency Department: Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Pregnancy Testing for Patients Requiring Diagnostic Imaging or Surgery in the Emergency Department: Clinical Effectiveness, Cost (...) -Effectiveness, and Guidelines Pregnancy Testing for Patients Requiring Diagnostic Imaging or Surgery in the Emergency Department: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Last updated: May 28, 2019 Project Number: RB1345-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of performing a pregnancy test prior to diagnostic imaging or surgery in the emergency department setting? What

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

5. Caesarean Delivery for Pregnancies in the First Stage of Labor: Clinical Effectiveness and Guidelines

Caesarean Delivery for Pregnancies in the First Stage of Labor: Clinical Effectiveness and Guidelines Caesarean Delivery for Pregnancies in the First Stage of Labor: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Caesarean Delivery for Pregnancies in the First Stage of Labor: Clinical Effectiveness and Guidelines Caesarean Delivery for Pregnancies in the First Stage of Labor: Clinical Effectiveness and Guidelines Last updated: September 9, 2019 Project Number (...) : RB1393-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What are the benefits and harms of caesarean delivery for Robson group 1 pregnancies with failure to progress in the latent phase of labor? What are the benefits and harms of caesarean delivery for Robson group 2A pregnancies with failure to progress in the latent phase of labor? What are the benefits and harms of caesarean delivery for Robson group 1 pregnancies with failure

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

6. Caesarean Delivery for Pregnancies in the Second Stage of Labor: Clinical Effectiveness and Guidelines

Caesarean Delivery for Pregnancies in the Second Stage of Labor: Clinical Effectiveness and Guidelines Caesarean Delivery for Pregnancies in the Second Stage of Labor: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Caesarean Delivery for Pregnancies in the Second Stage of Labor: Clinical Effectiveness and Guidelines Caesarean Delivery for Pregnancies in the Second Stage of Labor: Clinical Effectiveness and Guidelines Last updated: September 16, 2019 Project (...) Number: RB1394-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What are the benefits and harms of caesarean delivery for Robson group 1 pregnancies with failure to progress in the second stage of labour? What are the benefits and harms of caesarean delivery for Robson group 2A pregnancies with failure to progress in the second stage of labour? What are the evidence-based guidelines regarding the use of caesarean delivery for Robson

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

7. Updated Australian consensus statement on management of inherited bleeding disorders in pregnancy

Updated Australian consensus statement on management of inherited bleeding disorders in pregnancy Updated Australian consensus statement on management of inherited bleeding disorders in pregnancy | The Medical Journal of Australia mja-search search Use the for more specific terms. Title contains Body contains Date range from Date range to Article type Author's surname Volume First page doi: 10.5694/mja__.______ Search Reset  close Individual Login Purchase options Connect person_outline Login (...) keyboard_arrow_down Individual Login Purchase options menu search Advertisement close Updated Australian consensus statement on management of inherited bleeding disorders in pregnancy Scott Dunkley, Julie A Curtin, Anthony J Marren, Robert P Heavener, Simon McRae and Jennifer L Curnow Med J Aust 2019; 210 (7): . || doi: 10.5694/mja2.50123 Published online: 15 April 2019 Topics Abstract Introduction: There have been significant advances in the understanding of the management of inherited bleeding disorders

2019 MJA Clinical Guidelines

8. Non-invasive prenatal testing to determine the risk of autosomal trisomies 13, 18 and 21 in high-risk pregnancies

Non-invasive prenatal testing to determine the risk of autosomal trisomies 13, 18 and 21 in high-risk pregnancies 1 Translation of the key statement of the final report S16-06 Nicht invasive Pränataldiagnostik (NIPD) zur Bestimmung des Risikos autosomaler Trisomien 13, 18 und 21 bei Risikoschwangerschaften (Version 1.0; Status: 30 April 2018). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely (...) the German original text is absolutely authoritative and legally binding. Extract IQWiG Reports – Commission No. S16-06 Non-invasive prenatal testing (NIPT) to determine the risk of autosomal trisomies 13, 18 and 21 in high-risk pregnancies 1 Extract of final report S16-06 Version 1.0 Non-invasive prenatal testing (NIPT) 30 April 2018 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency in Health Care Topic: Non-invasive

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

9. Fingolimod (Gilenya): increased risk of congenital malformations; new contraindication during pregnancy and in women of childbearing potential not using effective contraception

Fingolimod (Gilenya): increased risk of congenital malformations; new contraindication during pregnancy and in women of childbearing potential not using effective contraception Fingolimod (Gilenya▼): increased risk of congenital malformations; new contraindication during pregnancy and in women of childbearing potential not using effective contraception - GOV.UK GOV.UK uses cookies which are essential for the site to work. We also use non-essential cookies to help us improve government digital (...) services. Any data collected is anonymised. By continuing to use this site, you agree to our use of cookies. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Fingolimod (Gilenya▼): increased risk of congenital malformations; new contraindication during pregnancy and in women of childbearing potential not using effective contraception Fingolimod is associated with an increased risk of major congenital malformations including cardiac, renal, and musculoskeletal defects, when

2019 MHRA Drug Safety Update

10. Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring: A 6-Year Follow-up of a Randomized Clinical Trial

Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring: A 6-Year Follow-up of a Randomized Clinical Trial Enamel defects of developmental origin affect up to 38% of schoolchildren and is recognized as a global public health challenge. The impaired enamel formation results in pain owing to hypersensitivity, posteruptive breakdowns, rapid caries progression, and extractions in some cases. The etiology is unknown; therefore, prevention (...) is currently not possible.To assess the association of a high-dose vitamin D supplementation in pregnant women with enamel defects and caries in their offspring.Post hoc analysis of a double-blind, single-center, randomized clinical trial, the Copenhagen Prospective Studies on Asthma in Childhood 2010 cohort (COPSAC2010). Enrollment began March 2009 and included 623 women recruited at 24 weeks of pregnancy and 588 of their children. A dental examination was completed at age 6 years in 496 of 588 children

2019 EvidenceUpdates

11. UK guidelines on the management of iron deficiency in pregnancy

UK guidelines on the management of iron deficiency in pregnancy UK guidelines on the management of iron deficiency in pregnancy - Pavord - - British Journal of Haematology - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term Guideline Free Access UK guidelines on the management of iron deficiency in pregnancy Department of Haematology, Oxford University Hospitals, Oxford, UK Women's Health Research (...) . I have read and accept the Wiley Online Library Terms and Conditions of Use. Shareable Link Use the link below to share a full-text version of this article with your friends and colleagues. Copy URL Share a link Share on ). The prevalence of anaemia in pregnancy remains high. In order to minimise adverse outcomes, including use of blood transfusion, further research is required to define optimal management, as many current recommendations are not supported by high quality evidence. Methods

2019 British Committee for Standards in Haematology

12. Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial. (PubMed)

Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial. Hypertension is the most common medical disorder in pregnancy, complicating one in ten pregnancies. Treatment of severely increased blood pressure is widely recommended to reduce the risk for maternal complications. Regimens for the acute treatment of severe hypertension typically include intravenous medications. Although

2019 Lancet

13. Calcium supplementation commencing before or early in pregnancy, for preventing hypertensive disorders of pregnancy. (PubMed)

Calcium supplementation commencing before or early in pregnancy, for preventing hypertensive disorders of pregnancy. The hypertensive disorders of pregnancy include pre-eclampsia, gestational hypertension, chronic hypertension, and undefined hypertension. Pre-eclampsia is considerably more prevalent in low-income than in high-income countries. One possible explanation for this discrepancy is dietary differences, particularly calcium deficiency. Calcium supplementation in the second half (...) of pregnancy reduces the serious consequences of pre-eclampsia, but has limited effect on the overall risk of pre-eclampsia. It is important to establish whether calcium supplementation before, and in early pregnancy (before 20 weeks' gestation) has added benefit. Such evidence could count towards justification of population-level interventions to improve dietary calcium intake, including fortification of staple foods with calcium, especially in contexts where dietary calcium intake is known

2019 Cochrane

14. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. (PubMed)

Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Intrahepatic cholestasis of pregnancy, characterised by maternal pruritus and increased serum bile acid concentrations, is associated with increased rates of stillbirth, preterm birth, and neonatal unit admission. Ursodeoxycholic acid is widely used as a treatment without an adequate evidence base. We aimed to evaluate whether ursodeoxycholic acid reduces adverse (...) perinatal outcomes in women with intrahepatic cholestasis of pregnancy.We did a double-blind, multicentre, randomised placebo-controlled trial at 33 hospital maternity units in England and Wales. We recruited women with intrahepatic cholestasis of pregnancy, who were aged 18 years or older and with a gestational age between 20 weeks and 40 weeks and 6 days, with a singleton or twin pregnancy and no known lethal fetal anomaly. Participants were randomly assigned 1:1 to ursodeoxycholic acid or placebo

2019 Lancet

15. Twin and triplet pregnancy

Twin and triplet pregnancy T Twin and triplet pregnancy win and triplet pregnancy NICE guideline Published: 4 September 2019 www.nice.org.uk/guidance/ng137 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement (...) . Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Twin and triplet pregnancy (NG137) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 59Contents Contents Overview 5 Who is it for? 5 Recommendations 6 Box 1 Chorionicity and amnionicity 6 1.1

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

16. Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic

Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic: a report of a joint workshop of the Society for Maternal-Fetal Medicine, American College of Obstetricians and Gynecologists, and American Society of Addiction Medicine - American Journal of Obstetrics & Gynecology Email/Username: Password: Remember me Search Terms Search within Search (...) Share this page: Access provided by Volume 221, Issue 1, Pages B5–B28 Substance use disorders in pregnancy: clinical, ethical, and research imperatives of the opioid epidemic: a report of a joint workshop of the Society for Maternal-Fetal Medicine, American College of Obstetricians and Gynecologists, and American Society of Addiction Medicine The workshop was convened at the 38th Annual Pregnancy Meeting of the Society for Maternal-Fetal Medicine in Dallas, TX, January 29–February 2, 2018. x Jeffrey

2019 Society for Maternal-Fetal Medicine

17. Syphilis Screening in Pregnancy

Syphilis Screening in Pregnancy September 2019 INTERIM GUIDELINE ON SYPHILIS SCREENING IN PREGNANCY In April 2019, the first case of congenital syphilis in British Columbia since 2013 was reported. A second case of congenital syphilis was reported in May 2019 in a stillborn delivered in January 2019. Current and past practice in BC has included screening for syphilis as part of routine care in the first trimester; historically subsequent syphilis screening has not been routinely recommended (...) unless there was concern for syphilis risk during pregnancy. There have been ongoing discussions between the BC Centre for Disease Control’s Sexually Transmitted Infections (BCCDC STI) team and expert partners and stakeholders about the best way to approach syphilis screening in pregnancy. Recent epidemiologic syphilis trends seen in BC – including increased overall rates, increased rates in females of reproductive age, along with an increasing number of infectious syphilis cases among males who

2019 British Columbia Perinatal Health Program

18. Pregnancy duration and endometrial cancer risk: nationwide cohort study. (PubMed)

Pregnancy duration and endometrial cancer risk: nationwide cohort study. To explore the association between pregnancy duration and risk of endometrial cancer.Nationwide register based cohort study.Denmark.All Danish women born from 1935 to 2002.Relative risk (incidence rate ratio) of endometrial cancer by pregnancy number, type, and duration, estimated using log-linear Poisson regression.Among 2 311 332 Danish women with 3 947 650 pregnancies, 6743 women developed endometrial cancer during 57 (...)  347 622 person years of follow-up. After adjustment for age, period, and socioeconomic factors, a first pregnancy was associated with a noticeably reduced risk of endometrial cancer, whether it ended in induced abortion (adjusted relative risk 0.53 (95% confidence interval 0.45 to 0.64) or childbirth (0.66, 0.61 to 0.72). Each subsequent pregnancy was associated with an additional reduction in risk, whether it ended in induced abortion (0.81, 0.77 to 0.86) or childbirth (0.86, 0.84 to 0.89

2019 BMJ

19. Bacterial vaginosis in pregnancy and risk of spontaneous preterm delivery

Bacterial vaginosis in pregnancy and risk of spontaneous preterm delivery Bacterial vaginosis, proposal for the Danish guideline meeting 2015 (version 190214) Page 1 Bacterial vaginosis in pregnancy and risk of spontaneous preterm delivery Approved at the obstetrical guideline-meeting January 2015 Danish Society of Obstetrics and Gynecology (DSOG) Update February 2019 The Lancet has now published reference 31b, by Subtil et al. (2018). The 2015 version of the DSOG guideline included (...) The objective of this guideline is to evaluate bacterial vaginosis in pregnancy concerning • Different treatments for prevention of preterm delivery. • Screening of pregnant women with low as well as high risk of sPTD. • Stratification into gestational ages below and above 16 weeks. • Diagnostic methods. Key words Bacterial vaginosis, vaginal pH, pH-glove, vaginal discharge, Nugent score, Amsel score, Gardnerella vaginalis, Mobiluncus species, preterm delivery, preterm birth, GRADE, clindamycin

2019 Nordic Federation of Societies of Obstetrics and Gynecology

20. SMFM Special Statement, research to knowledge: promoting the training of physician-scientists in the biology of pregnancy

SMFM Special Statement, research to knowledge: promoting the training of physician-scientists in the biology of pregnancy Research to knowledge: promoting the training of physician-scientists in the biology of pregnancy - American Journal of Obstetrics & Gynecology Email/Username: Password: Remember me Search Terms Search within Search Share this page: Volume 218, Issue 1, Pages B9–B13 To read this article in full, please review your options for gaining access at the bottom of the page (...) . Research to knowledge: promoting the training of physician-scientists in the biology of pregnancy Society for Maternal-Fetal Medicine (SMFM) , x Yoel Sadovsky Affiliations Magee-Womens Research Institute, University of Pittsburgh Department of Obstetrics, Gynecology and Reproductive Sciences, Pittsburgh, Pennsylvania, USA , MD a , x Aaron B. Caughey Affiliations Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland, Oregon, USA , MD, PhD b , x Michelle DiVito

2019 Society for Maternal-Fetal Medicine