Latest & greatest articles for pregnancy

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pregnancy or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on pregnancy and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for pregnancy

21. Tobacco and pregnancy

Tobacco and pregnancy 0 Tobacco and pregnancy A national guideline from the Danish Society of Obstetrics and Gynaecology Aims • To describe the risks of adverse fetal outcomes if a pregnant woman uses tobacco products. • To describe the risks of adverse outcomes among newborn children whose mothers use tobacco products during lactation. • To suggest a strategy for screening pregnant women for use of tobacco products. • To suggest a strategy for handling women who use tobacco products during (...) pregnancy and lactation. This guideline does not deal with social aspects related to the use of tobacco products by pregnant women or their partners, and it does not deal with tobacco products as markers of use of other drugs. Recommendations Evidence level Active and passive smoking, e-cigarettes and smokeless tobacco is discouraged during pregnancy. A/B All pregnant women should be asked about smoking status, exposure to passive smoking, use of e-cigarettes and smokeless tobacco at their first contact

2019 Nordic Federation of Societies of Obstetrics and Gynecology

22. Urological diseases and pregnancy

Urological diseases and pregnancy DSOG 2019 Urology and pregnancy Page 1 of 3 Urological diseases and pregnancy The guideline was approved by DSOG (Danish Society of Obstetric and Gynecology) in January 2019. Members of the working group: Al-Saudi Noor, Eskildsen Morten, Fuglsang Jens, Ravn Christine, Ryhammer Allan (Urologist), Smed Vibe, Storgaard Lone Correspondence: Lone Storgaard Lone.Storgaard.01@regionh.dk Summary of clinical recommendations: Hydronephrosis Recommendation Level (...) in case of failure of other treatments. Atosiban is optional during the procedure. 3-4 D Decompression of the kidney is indicated in case of septic patient, persistent severe pain or persistent obstruction. 2b B Hematuria Recommendation Level of evidence Recommendation There is no higher risk of hypertensive disorders, preterm delivery or small for gestational age in case of idiopathic hematuria 2A-3 B DSOG 2019 Urology and pregnancy Page 2 of 3 Persistent microscopic hematuria after delivery could

2019 Nordic Federation of Societies of Obstetrics and Gynecology

23. Effect of antenatal dietary interventions in maternal obesity on pregnancy weight-gain and birthweight: Healthy Mums and Babies (HUMBA) randomized trial

Effect of antenatal dietary interventions in maternal obesity on pregnancy weight-gain and birthweight: Healthy Mums and Babies (HUMBA) randomized trial Pregnancy interventions that improve maternal and infant outcomes are urgently needed in populations with high rates of obesity. We undertook the Healthy Mums and Babies (HUMBA) randomized controlled trial to assess the effect of dietary interventions and or probiotics in a multiethnic population of pregnant women with obesity, living (...) in an area of high deprivation.To determine whether a culturally tailored dietary intervention and or daily probiotic capsules in pregnant women with obesity reduces the co-primary outcomes of (1) excessive gestational weight gain (mean >0.27 kg/week) and (2) birthweight.We conducted a 2 × 2 factorial, randomized controlled trial in women without diabetes at pregnancy booking, body mass index ≥30 kg/m2, and a singleton pregnancy. At 12+0 to 17+6 weeks' gestation, eligible women were randomized

2019 EvidenceUpdates

24. Could the YEARS algorithm be used to exclude pulmonary embolism during pregnancy? Data from the CT-PE-pregnancy study

Could the YEARS algorithm be used to exclude pulmonary embolism during pregnancy? Data from the CT-PE-pregnancy study The recently proposed YEARS algorithm was shown to safely exclude pulmonary embolism (PE) and reduce the use of computed tomography pulmonary angiography (CTPA) among pregnant women with suspected PE. Our aim was to externally validate this finding.We performed a post hoc analysis of a prospective management outcome study for PE diagnosis in pregnant women. PE was diagnosed

2019 EvidenceUpdates

25. Viral rash in pregnancy

Viral rash in pregnancy Viral rash in pregnancy - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Viral rash in pregnancy Information on the investigation, diagnosis and management of a pregnant woman who has, or is exposed to, viral rash illness. Published 1 January 2011 Last updated 22 July 2019 — From: Documents Ref: PHE publications gateway number GW-231 If you use assistive technology (...) covers rash illnesses caused by parvovirus B19 ( Telephone: 0300 123 1002 Copies of most printed publications can now be ordered online. Login to register and place your order. contains additional information. Published 1 January 2011 Last updated 22 July 2019 22 July 2019 Added new quick reference guide for health professionals. 21 March 2019 Updated 'Investigation, diagnosis and management of exposure to viral rash illness in pregnancy' document. 1 February 2016 Added link to information on Zika

2019 Public Health England

26. Chronic renal diseases and pregnancy

Chronic renal diseases and pregnancy 1 Chronic renal diseases and pregnancy These guidelines were approved by DSOG (Danish Society of Obstetrics and Gynecology) in January 2019. Members of the working group: Andersen Torvin Lise Lotte, Damholt Brimnes Mette (Nephrologist), Eskildsen Morten, Kammerlander Heidi, Ovesen Per, Pedersen Woetmann Berit, Ravn Christine, Scheller Madrid Nikolai, Smed Vibe, Storgaard Lone Correspondence: Lone Storgaard Lone.Storgaard.01@regionh.dk 1. Recommendations (...) in English (4 pages) 2. Entire guideline in Danish (35 pages) Summary of clinical recommendations: Chronic Kidney Disease and pregnancy: CKD Recommendations Level of evidence Recommendation Preconception Counselling in cooperation with a nephrologist and an obstetrician with special interest in nephrology A Level of renal impairment, presence of hypertension and proteinuria are the strongest prognostics for the outcome of the pregnancy as well as the risk of progression of renal disease /progression

2019 Nordic Federation of Societies of Obstetrics and Gynecology

27. Group B streptococci during pregnancy

Group B streptococci during pregnancy Group B streptococci during pregnancy Danish Society of Obstetrics and Gynecology Approved March 17 – 2019 • Recommendations in English (3 pages) • Entire Danish guideline (35 pages) Summary of clinical recommendations: GBS-bacteriuria or GBS in vaginal swabs during pregnancy Asymptomatic bacteriuria with Group B Streptococci (GBS) is defined as the occurrence of = 10 4 CFU/ml in 2 cultures taken 24 hours apart B Asymptomatic bacteriuria with GBS (...) is recommended to be treated at the time of diagnosis C UTI with GBS is defined as the occurrence of = 10 4 CFU/ml together with symptoms of UTI B The indication for Intrapartum Antibiotic Prophylaxis (IAP) will depend on the examination and treatment regime chosen (see below), when symptomatic or asymptomatic GBS bacteriuria has been found during the current pregnancy. D The recommended antibiotic regime in asymptomatic GBS bacteriuria as well as symptomatic GBS UTI 1. Tbl Phenoxymetylpenicillin 1 MIE x 3

2019 Nordic Federation of Societies of Obstetrics and Gynecology

28. Vitamin D supplementation for women during pregnancy. (PubMed)

Vitamin D supplementation for women during pregnancy. Vitamin D supplementation during pregnancy may be needed to protect against adverse pregnancy outcomes. This is an update of a review that was first published in 2012 and then in 2016.To examine whether vitamin D supplementation alone or in combination with calcium or other vitamins and minerals given to women during pregnancy can safely improve maternal and neonatal outcomes.For this update, we searched Cochrane Pregnancy and Childbirth's (...) Trials Register (12 July 2018), contacted relevant organisations (15 May 2018), reference lists of retrieved trials and registries at clinicaltrials.gov and WHO International Clinical Trials Registry Platform (12 July 2018). Abstracts were included if they had enough information to extract the data.Randomised and quasi-randomised trials evaluating the effect of supplementation with vitamin D alone or in combination with other micronutrients for women during pregnancy in comparison to placebo

2019 Cochrane

29. Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study. (PubMed)

Health outcomes of young children born to mothers who received 2009 pandemic H1N1 influenza vaccination during pregnancy: retrospective cohort study. To determine whether any association exists between exposure to 2009 pandemic H1N1 (pH1N1) influenza vaccination during pregnancy and negative health outcomes in early childhood.Retrospective cohort study.Population based birth registry linked with health administrative databases in the province of Ontario, Canada.All live births from November (...) hazard ratio 1.05, 95% confidence interval 1.02 to 1.09) and decreased rates of gastrointestinal infections (adjusted incidence rate ratio 0.94, 0.91 to 0.98). These results were unchanged in sensitivity analyses accounting for any potential differential healthcare seeking behavior or access between exposure groups.No associations were observed between exposure to pH1N1 influenza vaccine during pregnancy and most five year pediatric health outcomes. Residual confounding may explain the small

2019 BMJ

30. Total serum bile acids or serum bile acid profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy. (PubMed)

Total serum bile acids or serum bile acid profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy. Intrahepatic cholestasis of pregnancy is a pregnancy-specific liver disorder, possibly associated with an increased risk of severe fetal adverse events. Total serum bile acids (TSBA) concentration, alone or in combination with serum aminotransferases, have been the most often used biomarkers for the diagnosis of intrahepatic cholestasis of pregnancy in clinical practice. Serum (...) bile acid profile, composed of primary or secondary, conjugated or non-conjugated bile acids, may provide more specific disease information.To assess and compare, independently or in combination, the diagnostic accuracy of total serum bile acids or serum bile acids profile, or both, for the diagnosis of intrahepatic cholestasis of pregnancy in pregnant women, presenting with pruritus. To define the optimal cut-off values for components of serum bile acid profile; to investigate possible sources

2019 Cochrane

31. Hypertension in pregnancy: diagnosis and management

Hypertension in pregnancy: diagnosis and management Hypertension in pregnancy: diagnosis Hypertension in pregnancy: diagnosis and management and management NICE guideline Published: 25 June 2019 www.nice.org.uk/guidance/ng133 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guideline represent the view of NICE, arrived at after careful consideration (...) be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Hypertension in pregnancy: diagnosis and management (NG133) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 54Contents Contents Overview 5 Who

2019 National Institute for Health and Clinical Excellence - Clinical Guidelines

32. Oral retinoid medicines: revised and simplified pregnancy prevention educational materials for healthcare professionals and women

Oral retinoid medicines: revised and simplified pregnancy prevention educational materials for healthcare professionals and women Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare professionals and women - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare (...) professionals and women New prescriber checklists, patient reminder cards, and pharmacy checklists are available to support the Pregnancy Prevention Programme in women taking acitretin, alitretinoin, and isotretinoin. Advice about the risk of neuropsychiatric reactions has been made consistent for all oral retinoid medicines. Published 19 June 2019 From: Therapeutic area: , , , , , Contents Advice for healthcare professionals about teratogenicity: following a detailed review, educational materials

2019 MHRA Drug Safety Update

33. Caffeine Intake During Pregnancy and Weight of Offspring in Childhood: A Systematic Review

Caffeine Intake During Pregnancy and Weight of Offspring in Childhood: A Systematic Review "Caffeine Intake During Pregnancy and Weight of Offspring in Childhood:" by Gina M. McCoy and Evelyn L. Evans < > > > > > Title Author Date of Graduation Summer 8-10-2019 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies Rights . Abstract Background : Childhood obesity currently affects one third of the United States’ youth. Meeting criteria for overweight (...) is present in-utero . The current review explores the relationship between caffeine consumption during pregnancy and the weight of offspring in childhood. The purpose of this review is to organize and critically appraise the current data in order to realign our standard of care with the most recent information. Preventing childhood obesity is our best line of defense for our children and the health of our nation. Method : A comprehensive search of MEDLINE-PubMed, Web of Science, CINAHL-EBSCO, and MEDLINE

2019 Pacific University EBM Capstone Project

34. Pregnancy and early life: reducing stillbirth and infant death

Pregnancy and early life: reducing stillbirth and infant death Pregnancy and early life: reducing stillbirth and infant death - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance Pregnancy and early life: reducing stillbirth and infant death A planning tool to examine factors that influence stillbirth and infant death at the population level, rather than in individual clinical care. Published 12 March 2019

2019 Public Health England

35. Cervical pessary for preventing preterm birth in twin pregnancies with maternal short cervix after an episode of threatened preterm labor: randomised controlled trial

Cervical pessary for preventing preterm birth in twin pregnancies with maternal short cervix after an episode of threatened preterm labor: randomised controlled trial No intervention has proved effective to date in reducing the spontaneous preterm birth rate in twin pregnancies following an episode of threatened preterm labor and with a short cervix remaining. This study was designed to ascertain whether cervical pessaries are useful in preventing spontaneous preterm birth in women with twin (...) pregnancies and a short cervix remaining after a threatened preterm labor episode.This open, randomized, controlled trial was conducted in 132 pregnant women who had not delivered 48 hours after a threatened preterm labor episode and had a short cervix remaining (≤20 mm between 240 and 296 weeks and ≤10 mm between 300 and 336 weeks). Patients were randomly assigned to cervical pessary (n = 67) or routine management (n = 65). The primary outcome was the spontaneous preterm birth rate before 34 weeks

2019 EvidenceUpdates

36. Doxylamine/pyridoxine (Xonvea) for treating nausea and vomiting of pregnancy

Doxylamine/pyridoxine (Xonvea) for treating nausea and vomiting of pregnancy Do Doxylamine/p xylamine/pyrido yridoxine (X xine (Xon onv vea) for treating ea) for treating nausea and v nausea and vomiting of pregnancy omiting of pregnancy Evidence summary Published: 24 June 2019 www.nice.org.uk/guidance/es20 pathways K Ke ey messages y messages The content of this evidence review was up-to-date in April 2019. See summaries of product characteristics (SPCs), British national formulary (BNF (...) ) or the Medicines and Healthcare products Regulatory Agency (MHRA) or NICE websites for up-to-date information. Xonvea (Alliance Pharmaceuticals) is a delayed-release tablet containing doxylamine succinate 10 mg (an antihistamine) and pyridoxine hydrochloride 10 mg (vitamin B6). In July 2018, it was granted a marketing authorisation for treating nausea and vomiting of pregnancy in women (aged 18 years or older) who do not respond to conservative management. Doxylamine/pyridoxine is taken every day

2019 National Institute for Health and Clinical Excellence - Advice

37. Self-reported Physical Health of Women Who Did and Did Not Terminate Pregnancy After Seeking Abortion Services: A Cohort Study. (PubMed)

Self-reported Physical Health of Women Who Did and Did Not Terminate Pregnancy After Seeking Abortion Services: A Cohort Study. Research demonstrates worse short-term morbidity and mortality associated with childbirth than with abortion, but little research has examined long-term physical health in women with unwanted pregnancies after abortion versus childbirth.To examine the physical health of women who seek and receive or are denied abortion.Prospective cohort study.30 U.S. abortion

2019 Annals of Internal Medicine

38. Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients. (PubMed)

Association of Blood Donor Sex and Prior Pregnancy With Mortality Among Red Blood Cell Transfusion Recipients. Evidence regarding associations of blood donor sex with mortality among red blood cell transfusion recipients is conflicting.To study associations of donor sex and prior pregnancy with mortality of transfusion recipients.Data from 3 retrospective cohorts of transfusion recipients (the Kaiser Permanente Northern California [KPNC] and Recipient Epidemiology and Donor Evaluation Study-III

2019 JAMA

39. Critical Care in Pregnancy

Critical Care in Pregnancy Sign In (ACOG) Sign in to your ACOG account Email is required. Please enter valid Email. was not found in our system. Would you like to associated with your account? Forgot your email address? JSOG Member? © 2019 - American College of Obstetricians and Gynecologists

2019 American College of Obstetricians and Gynecologists

40. Pregnancy and Heart Disease

Pregnancy and Heart Disease Sign In (ACOG) Sign in to your ACOG account Email is required. Please enter valid Email. was not found in our system. Would you like to associated with your account? Forgot your email address? JSOG Member? © 2019 - American College of Obstetricians and Gynecologists

2019 American College of Obstetricians and Gynecologists