Latest & greatest articles for pressure ulcer

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Top results for pressure ulcer

201. Clinical utility and cost-effectiveness of an air suspension bed in the prevention of pressure ulcers. (PubMed)

Clinical utility and cost-effectiveness of an air suspension bed in the prevention of pressure ulcers. To determine, in critically ill patients at risk, both the clinical utility and cost-effectiveness of using an air suspension bed in the prevention of pressure ulcers.Randomized, parallel group, controlled clinical trial with accompanying cost-effectiveness analysis.30-bed multidisciplinary intensive care unit.100 consecutive patients at risk for the development of pressure ulcers randomly (...) assigned to receive treatment on either an air suspension bed or a standard intensive care unit bed. Patients considered at risk were those at least 17 years of age with an Acute Physiology and Chronic Health Evaluation II (APACHE II) score greater than 15 who had an expected intensive care unit stay of at least 3 days.The development of pressure ulcers by site and severity and the costs associated with each of the two programs.The air suspension bed was associated with fewer patients developing single

1993 JAMA

202. Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. (PubMed)

Platelet-derived growth factor BB for the treatment of chronic pressure ulcers. A randomised, phase I/II, double-blind, placebo-controlled study was designed to assess the effect of topically applied recombinant human BB homodimeric platelet-derived growth factor (rPDGF-BB) on healing of chronic pressure ulcers. Twenty patients were randomly allocated daily treatment for 28 days with 1, 10, or 100 micrograms/ml rPDGF-BB (0.01, 0.1, or 1.0 micrograms per cm2 ulcer area) or placebo. Patients (...) treated with 100 micrograms/ml rPDGF-BB showed a greater healing response than the placebo group, but the lower doses had little effect. After 28 days, ulcers treated with 100 micrograms/ml rPDGF-BB were smaller than those treated with placebo (mean [SE] volume 6.4 [4.0] vs 21.8 [5.6]% of day 0 volume). There were no toxic effects. These preliminary findings suggest that rPDGF-BB is a potent wound-healing agent in soft tissue.

1992 Lancet