Latest & greatest articles for sedation

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Top results for sedation

41. Chloral hydrate as a sedating agent for neurodiagnostic procedures in children. (PubMed)

Chloral hydrate as a sedating agent for neurodiagnostic procedures in children. Paediatric neurodiagnostic investigations, including brain neuroimaging and electroencephalography (EEG), play an important role in the assessment of neurodevelopmental disorders. The use of an appropriate sedative agent is important to ensure the successful completion of the neurodiagnostic procedures, particularly in children, who are usually unable to remain still throughout the procedure.To assess (...) children. The studies were all conducted in hospitals that provided neurodiagnostic services. Most studies assessed the proportion of sedation failure during the neurodiagnostic procedure, time for adequate sedation, and potential adverse effects associated with the sedative agent.The methodological quality of the included studies was mixed, as reflected by a wide variation in their 'Risk of bias' profiles. Blinding of the participants and personnel was not achieved in most of the included studies

2017 Cochrane

42. Forced air warming during sedation in the cardiac catheterisation laboratory: a randomised controlled trial (Full text)

Forced air warming during sedation in the cardiac catheterisation laboratory: a randomised controlled trial Forced air warming (FAW) during general anaesthesia is a safe and effective intervention used to reduce hypothermia. The objective of this study was to determine if FAW reduces hypothermia when used for procedures performed with sedation in the cardiac catheterisation laboratory.A parallel-group randomised controlled trial was conducted. Adults receiving sedation in a cardiac

2017 EvidenceUpdates PubMed

43. Risk Factors for Adverse Events in Emergency Department Procedural Sedation for Children (Full text)

Risk Factors for Adverse Events in Emergency Department Procedural Sedation for Children Procedural sedation for children undergoing painful procedures is standard practice in emergency departments worldwide. Previous studies of emergency department sedation are limited by their single-center design and are underpowered to identify risk factors for serious adverse events (SAEs), thereby limiting their influence on sedation practice and patient outcomes.To examine the incidence and risk factors (...) associated with sedation-related SAEs.This prospective, multicenter, observational cohort study was conducted in 6 pediatric emergency departments in Canada between July 10, 2010, and February 28, 2015. Children 18 years or younger who received sedation for a painful emergency department procedure were enrolled in the study. Of the 9657 patients eligible for inclusion, 6760 (70.0%) were enrolled and 6295 (65.1%) were included in the final analysis.The primary risk factor was receipt of sedation

2017 EvidenceUpdates PubMed

44. Oral Midazolam and Intranasal Midazolam are equally effective when used for conscious sedations in short procedures in pediatric dentistry.

Oral Midazolam and Intranasal Midazolam are equally effective when used for conscious sedations in short procedures in pediatric dentistry. UTCAT3283, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Oral Midazolam and Intranasal Midazolam are equally effective when used for conscious sedations in short procedures in pediatric dentistry. Clinical Question For a dental pediatric patient, will intranasal midazolam (...) as compared to oral midazolam be more effective for use in conscious sedation? Clinical Bottom Line For dental pediatric patient intranasal midazolam and oral midazolam are equally effective when used in conscious sedation in short procedures in pediatric dentistry. Intranasal midazolam has a shorter onset and shorter working time when compared to oral midazolam. It is important to take the onset time and duration time into consideration when deciding which medications to use for treatment of pediatric

2017 UTHSCSA Dental School CAT Library

45. Considerations for pediatric burn sedation and analgesia (Full text)

Considerations for pediatric burn sedation and analgesia Burn patients experience anxiety and pain in the course of their injury, treatment, and recovery. Hence, treatment of anxiety and pain is paramount after burn injury. Children, in particular, pose challenges in anxiety and pain management due to their unique physiologic, psychologic, and anatomic status. Burn injuries further complicate pain management and sedation as such injuries can have effects on medication response and elimination (...) . Burn injuries further complicate pain management and sedation as such injuries can have effects on medication response and elimination. The purpose of this review is to describe the challenges associated with management of anxiety, pain, and sedation in burned children and to describe the different options for treatment of anxiety and pain in burned children.

2017 Burns & trauma PubMed

46. Effect of Different Sedation Regimes on Cognitive Functions in Colonoscopy (Full text)

Effect of Different Sedation Regimes on Cognitive Functions in Colonoscopy To compare the effects of propofol/remifentanil and meperidine/midazolam on postprocedure cognitive function.A total of 100 American Society of Anesthesiologists (ASA) score I to III patients undergoing elective colonoscopy were taken into the study and divided into two groups. Exclusion criteria were patient refusal, mini mental test (MMT) <26, The Amsterdam Preoperative Anxiety and Information Scale (APAIS) >10 (...) was given when BIS was >80. Observer's Assessment of Alertness/Sedation scale (OAA/S) and Facial Pain Score (FPS) values were recorded. Cognitive function was measured by Trieger Dot Test (TDT) and Digit Symbol Substitution Test (DSST).The study was concluded with 100 patients. Heart rate was slower and BIS values were lower in group RP throughout the procedure. Blood pressure was lower in group RP without clinical significance. There was no difference concerning recovery time and visual analog scores

2017 Euroasian journal of hepato-gastroenterology PubMed

47. Postinjection delirium/sedation syndrome in patients with schizophrenia receiving olanzapine long-acting injection: results from a large observational study (Full text)

Postinjection delirium/sedation syndrome in patients with schizophrenia receiving olanzapine long-acting injection: results from a large observational study Postinjection delirium/sedation syndrome (PDSS) has been reported uncommonly during treatment with olanzapine long-acting injection (LAI), a sustained-release formulation of olanzapine.The primary aim of the study was to estimate the incidence per injection and per patient of PDSS events in adult patients with schizophrenia who were

2017 BJPsych open PubMed

48. Adverse Events With Ketamine Versus Ketofol for Procedural Sedation on Adults: A Double-blind, Randomized Controlled Trial (Full text)

Adverse Events With Ketamine Versus Ketofol for Procedural Sedation on Adults: A Double-blind, Randomized Controlled Trial The goal of our study was to compare the frequency and severity of recovery reactions between ketamine and ketamine-propofol 1:1 admixture ("ketofol").We performed a multicentric, randomized, double-blind trial in which adult patients received emergency procedural sedations with ketamine or ketofol. Our primary outcome was the proportion of unpleasant recovery reactions (...) or respiratory events as well as satisfaction scores were similar. Significantly fewer patients experienced emesis with ketofol, with a threefold reduction in incidence compared with ketamine.We found a significant reduction in recovery reactions and emesis frequencies among adult patients receiving emergency procedural sedations with ketofol, compared with ketamine.© 2017 by the Society for Academic Emergency Medicine.

2017 EvidenceUpdates PubMed

49. General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke) (Full text)

General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke) Retrospective studies have found that patients receiving general anesthesia for endovascular treatment in acute ischemic stroke have worse neurological outcome compared with patients receiving conscious sedation. In this prospective randomized single-center study, we investigated the impact of anesthesia technique on neurological outcome in acute (...) ischemic stroke patients.Ninety patients receiving endovascular treatment for acute ischemic stroke in 2013 to 2016 were included and randomized to general anesthesia or conscious sedation. Difference in neurological outcome at 3 months, measured as modified Rankin Scale score, was analyzed (primary outcome) and early neurological improvement of National Institutes of Health Stroke Scale and cerebral infarction volume. Age, sex, comorbidities, admission National Institutes of Health Stroke Scale score

2017 EvidenceUpdates PubMed

50. Opioid antagonists with minimal sedation for opioid withdrawal. (Full text)

Opioid antagonists with minimal sedation for opioid withdrawal. Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of long-term substitution treatment.To assess the effects of opioid antagonists plus minimal sedation for opioid withdrawal. Comparators were placebo as well as more established approaches to detoxification, such as tapered doses of methadone, adrenergic agonists, buprenorphine and symptomatic medications.We updated our searches of the following (...) databases to December 2016: CENTRAL, MEDLINE, Embase, PsycINFO and Web of Science. We also searched two trials registers and checked the reference lists of included studies for further references to relevant studies.We included randomised and quasi-randomised controlled clinical trials along with prospective controlled cohort studies comparing opioid antagonists plus minimal sedation versus other approaches or different opioid antagonist regimens for withdrawal in opioid-dependent participants.We used

2017 Cochrane PubMed

51. Clonidine for sedation and analgesia for neonates receiving mechanical ventilation. (Full text)

Clonidine for sedation and analgesia for neonates receiving mechanical ventilation. Although routine administration of pharmacologic sedation or analgesia during mechanical ventilation in preterm neonates is not recommended, its use in clinical practice remains common. Alpha-2 agonists, mainly clonidine and dexmedetomidine, are used as adjunctive (or alternative) sedative agents alongside opioids and benzodiazepines. Clonidine has not been systematically assessed for use in neonatal sedation (...) ; and pharmacologic sedation as a co-intervention.We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 12) in the Cochrane Library, MEDLINE via PubMed (1966 to January 10, 2017), Embase (1980 to January 10, 2017), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL; 1982 to January 10, 2017). We also searched clinical trials databases, conference proceedings, and the reference lists

2017 Cochrane PubMed

52. Short-Term Health-Related Quality of Life of Critically Ill Children Following Daily Sedation Interruption

Short-Term Health-Related Quality of Life of Critically Ill Children Following Daily Sedation Interruption PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

53. Clinical study of midazolam sequential with dexmedetomidine for agitated patients undergoing weaning to implement light sedation in intensive care unit. (PubMed)

Clinical study of midazolam sequential with dexmedetomidine for agitated patients undergoing weaning to implement light sedation in intensive care unit. To evaluate midazolam sequential with dexmedetomidine for agitated patients undergoing weaning to implement light sedation in ICU.This randomized, prospective study was conducted in Tianjin Third Central Hospital, China. Using a sealed-envelope method, the patients were randomly divided into 2 groups (40 patients per group). Each patient (...) of group A received an initial loading dose of midazolam at 0.3-3mg/kg·h 24 h before extubation, followed by an infusion of dexmedetomidine at a rate of 0.2-1 μg/kg·h until extubation. Each patient of group B received midazolam at a dose of 0.3-3 mg/kg·h until extubation. The dose of sedation was regulated according to RASS sedative scores maintaining in the range of -2-1. All patients were continuously monitored for 60 min after extubation. During the course, heart rate (HR), mean artery pressure (MAP

2017 Chinese journal of traumatology = Zhonghua chuang shang za zhi

54. Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment

Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment | CADTH.ca CADTH Document Viewer Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment Table of Contents Search this document Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment March 2017 Summary Findings from a focused clinical review of the comparative effectiveness (...) ) in specific populations and settings, based on clinical studies selected from the clinical review in consultation with a Canadian clinical expert as most relevant to the Canadian clinical setting. The results of the analysis indicate that dexmedetomidine may be cost saving based on the underlying assumptions, which may differ between clinical settings. Background In 2014, CADTH undertook two rapid response projects, Dexmedetomidine for Sedation of Patients in the ICU or PICU: Review of Clinical

2017 CADTH - Plasma Products

55. Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment

Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment | CADTH.ca CADTH Document Viewer Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment Table of Contents Search this document Dexmedetomidine for Sedation in the Critical Care Setting: An Economic Assessment March 2017 Summary Findings from a focused clinical review of the comparative effectiveness (...) ) in specific populations and settings, based on clinical studies selected from the clinical review in consultation with a Canadian clinical expert as most relevant to the Canadian clinical setting. The results of the analysis indicate that dexmedetomidine may be cost saving based on the underlying assumptions, which may differ between clinical settings. Background In 2014, CADTH undertook two rapid response projects, Dexmedetomidine for Sedation of Patients in the ICU or PICU: Review of Clinical

2017 CADTH - Plasma Products

56. Capnography versus standard monitoring for emergency department procedural sedation and analgesia. (Full text)

Capnography versus standard monitoring for emergency department procedural sedation and analgesia. Procedural sedation and analgesia (PSA) is used frequently in the emergency department (ED) to facilitate painful procedures and interventions. Capnography, a monitoring modality widely used in operating room and endoscopy suite settings, is being used more frequently in the ED setting with the goal of reducing cardiopulmonary adverse events. As opposed to settings outside the ED

2017 Cochrane PubMed

57. Implication of general anaesthetic and sedation techniques in temporomandibular joint disorders - a systematic review. (PubMed)

Implication of general anaesthetic and sedation techniques in temporomandibular joint disorders - a systematic review. The purpose of this study was to conduct a systematic review of the literature on temporomandibular joint damage directly related to general anaesthesia and sedation. We searched MEDLINE, SCOPUS and the COCHRANE Library for titles and abstracts containing terms related to the subject. The search delimiters were analytical and descriptive studies with abstracts in Spanish (...) , German, English or French, with no time limit. The search was updated in January 2015. Of the 398 articles found, 89 were duplicates and only 28 were of interest. Of these, 23 (82.14%) were case and case series reports, 4 (14.28%) were longitudinal studies and 1 (3.57%) was a cross-sectional study. General anaesthesia and sedation are risk factors for temporomandibular joint damage because of the drop in muscle tone caused by the drugs employed and because of airway management manoeuvres involving

2017 Journal of stomatology, oral and maxillofacial surgery

58. Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit

Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

59. IM Ketamine for Prehospital Sedation of the Agitated Patient

IM Ketamine for Prehospital Sedation of the Agitated Patient Emergency Medicine > Journal Club > Archive > November 2016 Toggle navigation November 2016 IM Ketamine for Prehospital Sedation of the Agitated Patient Vignette You are working a night shift in EM-1 and have just started to catch up after signout, consisting of more than a few inebriated patients awaiting sobriety, when you hear commotion out in the hall. EMS and police are bringing in a large, screaming, Blailing, adult male patient (...) that might reduce the chances for injury of the patient and providers? How about something that is more rapid in onset than our old “5 and 2”? You remember hearing that ketamine is now being stocked on some ambulances for this purpose. When you wake up the next day after your shift you decide to look into the evidence behind prehospital ketamine for agitated patients. PICO Question Population: Adult patients with severe agitation requiring chemical sedation in the prehospital setting Intervention: IM

2017 Washington University Emergency Medicine Journal Club

60. Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit. (Full text)

Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit. Proper sedation for neonates undergoing uncomfortable procedures may reduce stress and avoid complications. Midazolam is a short-acting benzodiazepine that is used increasingly in neonatal intensive care units (NICUs). However, its effectiveness as a sedative in neonates has not been systematically evaluated.Primary objeciveTo assess the effectiveness of intravenous midazolam infusion for sedation (...) , as evaluated by behavioural and/or physiological measurements of sedation levels, in critically ill neonates in the NICU. Secondary objectivesTo assess effects of intravenous midazolam infusion for sedation on complications including the following.1. Incidence of intraventricular haemorrhage (IVH)/periventricular leukomalacia (PVL).2. Mortality.3. Occurrence of adverse effects associated with the use of midazolam (hypotension, neurological abnormalities).4. Days of ventilation.5. Days of supplemental

2017 Cochrane PubMed