Latest & greatest articles for sepsis

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Top results for sepsis

161. Prognostic Accuracy of Sepsis-3 Criteria for In-Hospital Mortality Among Patients With Suspected Infection Presenting to the Emergency Department. (Full text)

Prognostic Accuracy of Sepsis-3 Criteria for In-Hospital Mortality Among Patients With Suspected Infection Presenting to the Emergency Department. An international task force recently redefined the concept of sepsis. This task force recommended the use of the quick Sequential Organ Failure Assessment (qSOFA) score instead of systemic inflammatory response syndrome (SIRS) criteria to identify patients at high risk of mortality. However, these new criteria have not been prospectively validated (...) in some settings, and their added value in the emergency department remains unknown.To prospectively validate qSOFA as a mortality predictor and compare the performances of the new sepsis criteria to the previous ones.International prospective cohort study, conducted in France, Spain, Belgium, and Switzerland between May and June 2016. In the 30 participating emergency departments, for a 4-week period, consecutive patients who visited the emergency departments with suspected infection were included

2017 JAMA PubMed

162. Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines

Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines | CADTH.ca Find the information you need Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines Recognition and Diagnosis of Sepsis in Adults: A Review of Evidence-Based Guidelines Published on: January 13, 2017 Project Number: RC0841-000 Product Line: Research Type: Other Diagnostics Report Type (...) : Summary with Critical Appraisal Result type: Report Question What are the evidence-based guidelines regarding the use of tests or procedures for the recognition and diagnosis of sepsis in adults with suspected sepsis? Key Message Six evidence-based guidelines were identified for diagnostic tests or processes for the recognition and detection of sepsis in adult populations. Three of these guidelines explored the recognition and detection of sepsis in broader populations, while three others focused

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

163. Effectiveness of provider strategies for the early recognition of clinical deterioration due to sepsis in pediatric patients: a systematic review protocol. (PubMed)

Effectiveness of provider strategies for the early recognition of clinical deterioration due to sepsis in pediatric patients: a systematic review protocol. The objective of this review is to determine the effectiveness of provider strategies for the early recognition of clinical deterioration due to sepsis in pediatric patients. Specifically, the review question is: among pediatric, hospitalized patients, up to 18 years of age, what is the effectiveness of clinical assessment compared with use (...) of early recognition screening tools for the recognition of clinical deterioration due to sepsis?

2017 JBI database of systematic reviews and implementation reports

164. Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial

Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

165. Red blood cell transfusions are associated with lower mortality in patients with severe sepsis and septic shock: A propensity-matched analysis

Red blood cell transfusions are associated with lower mortality in patients with severe sepsis and septic shock: A propensity-matched analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

172. Statement on maternal sepsis

Statement on maternal sepsis Statement on maternal sepsis JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Statement on maternal sepsis View/ Open Rights View Statistics Altmetrics Share Citation World Health Organization . (‎2017)‎. Statement on maternal sepsis. World Health Organization. . License: CC BY-NC-SA 3.0 IGO Description 4 p. Gov't Doc # WHO/RHR/17.02 Collections

2017 WHO

173. Antibiotic utilisation in very low birth weight infants without sepsis or necrotising enterocolitis is associated with multiple adverse outcomes

Antibiotic utilisation in very low birth weight infants without sepsis or necrotising enterocolitis is associated with multiple adverse outcomes Antibiotic utilisation in very low birth weight infants without sepsis or necrotising enterocolitis is associated with multiple adverse outcomes | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how (...) we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antibiotic utilisation in very low birth weight infants without sepsis or necrotising

2017 Evidence-Based Medicine (Requires free registration)

174. High-dose Vitamin C for treatment of sepsis

High-dose Vitamin C for treatment of sepsis High-dose Vitamin C for treatment of sepsis High-dose Vitamin C for treatment of sepsis Mitchell MD, Umscheid CA Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell MD, Umscheid CA. High-dose Vitamin C for treatment of sepsis. Philadelphia: Center for Evidence-based Practice (CEP). 2017 (...) Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Ascorbic Acid; Humans; Sepsis; Vitamins Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania Health System, 3535 Market St. Suite 50, Philadelphia PA 19104 Email: Cep2@uphs.upenn.edu AccessionNumber 32018000170 Date abstract record published 16/04/2018 Health

2017 Health Technology Assessment (HTA) Database.

175. Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies

Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can (...) goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies Article Text Commentary: Emergency care Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies Joel Meyer 1 , Manu Shankar-Hari 1 , 2 Statistics from Altmetric.com Commentary on : Rowan KM, Angus DC, Bailey M

2017 Evidence-Based Medicine (Requires free registration)

176. Management of term infants at increased risk for early onset bacterial sepsis

Management of term infants at increased risk for early onset bacterial sepsis Early-onset neonatal bacterial sepsis (EOS) is sepsis occurring within the first seven days of life. This statement provides updated recommendations for the care of term (≥37 weeks’ gestational age) newborns at risk of EOS, during the first 24 h of life. Maternal group B streptococcal (GBS) colonization in the current pregnancy, GBS bacteruria, a previous infant with invasive GBS disease, prolonged rupture (...) of membranes (≥18 h), and maternal fever (temperature ≥38 o C) are the factors most commonly associated with EOS. These risk factors are additive; the presence of more than one factor increases the likelihood of EOS. At present, there is no laboratory test, including white blood cell indices, that has sufficient sensitivity to allow clinicians to safely rule out EOS. All unwell infants with clinical signs suggesting sepsis must be treated empirically with antibiotics, once cultures have been taken

2017 Canadian Paediatric Society

177. Clostridium perfringens sepsis complicated by right ventricular cardiogenic shock (Full text)

Clostridium perfringens sepsis complicated by right ventricular cardiogenic shock Clostridium perfringens sepsis has been ascribed a dismal prognosis when associated with massive intravascular haemolysis. We present a 71-year-old woman's fatal case which was compounded by isolated right ventricular cardiogenic shock. In this context, combined use of transthoracic echocardiography and pulmonary artery catheter monitoring is able to yield an individualized hemodynamic resuscitation. We discuss

2016 Journal of the Intensive Care Society PubMed

178. One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates. (PubMed)

One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates. Animal studies and trials in older children and adults suggest that a 'one dose per day' regimen of gentamicin is superior to a 'multiple doses per day' regimen.To compare the efficacy and safety of one dose per day compared to multiple doses per day of gentamicin in suspected or proven sepsis in neonates.Eligible studies were identified by searching the Cochrane Central (...) Group.Eleven RCTs were included (N = 574) and 28 excluded. All except one study enrolled infants of more than 32 weeks' gestation. Limited information suggested that infants in both 'once a day' as well as 'multiple doses a day' regimens showed adequate clearance of sepsis (typical RR 1.00, 95% CI 0.84 to 1.19; typical RD 0.00, 95% CI -0.19 to 0.19; 3 trials; N = 37). 'Once a day' gentamicin regimen was associated with fewer failures to attain peak level of at least 5 µg/ml (typical RR 0.22, 95% CI 0.11

2016 Cochrane

179. The microcirculation and its measurement in sepsis (Full text)

The microcirculation and its measurement in sepsis The microcirculation describes the smallest elements of the cardiovascular conducting system and is pivotal in the maintenance of homeostasis. Microcirculatory dysfunction is present early in the pathophysiology of sepsis, with the extent of microcirculatory derangement relating to disease severity and prognosis in ICU patients. However, at present microcirculatory function is not routinely monitored at the bedside. This article describes (...) the pathophysiology of microcirculatory derangements in sepsis, methods of its measurement and evidence to support their clinical use.

2016 Journal of the Intensive Care Society PubMed

180. Continuous versus Intermittent ?-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials

Continuous versus Intermittent ?-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2016 PedsCCM Evidence-Based Journal Club