Latest & greatest articles for side effects

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Top results for side effects

61. No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ

No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here No differences in efficacy of atypical and typical antipsychotics in early psychosis, but side effects differ Article Text Therapeutics No differences in efficacy

2011 Evidence-Based Mental Health

62. Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons

Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antidepressant non-adherence is common among veterans, with ineffectiveness and side effects as commonly reported reasons Article Text Prevalence

2011 Evidence-Based Mental Health

63. Patients with cancer believed that chemotherapy had to ?hurt? or ?cause side effects? to be effective

Patients with cancer believed that chemotherapy had to ?hurt? or ?cause side effects? to be effective Patients with cancer believed that chemotherapy had to “hurt” or “cause side effects” to be effectiveCommentary | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Patients with cancer believed that chemotherapy had to “hurt” or “cause side effects” to be effectiveCommentary Article Text Qualitative Patients with cancer believed

2010 Evidence-Based Nursing

64. A Systematic Review of Side Effects of Nucleoside and Nucleotide Drugs Used for Treatment of Chronic Hepatitis B. (PubMed)

A Systematic Review of Side Effects of Nucleoside and Nucleotide Drugs Used for Treatment of Chronic Hepatitis B. Although nucleosides and nucleotides have a good safety record for the treatment of hepatitis B, there have been no systematic reviews on this topic. We searched Medline to include studies of the oral antiviral agents for hepatitis B and adverse events, with at least 48 weeks of follow-up from the initiation of treatment with the drug. Important toxicities include nephrotoxicity (...) , myopathy, and resistance. It is often difficult to ascertain whether an adverse effect is from the study drug or the natural progression of the disease. Further safety data are needed for the newer agents and for all agents with regard to patients with decompensated liver disease, renal dysfunction, the elderly, children, and pregnant women.

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2010 Current hepatitis reports

65. Incisional continuous fascia iliaca block provides more effective pain relief and fewer side effects than opioids after pelvic osteotomy in children (PubMed)

Incisional continuous fascia iliaca block provides more effective pain relief and fewer side effects than opioids after pelvic osteotomy in children Intravenous opioid therapy is frequently used for postoperative pain management in children after orthopedic surgery but causes side effects such as respiratory depression, vomiting, sedation, and urinary retention. To investigate whether a continuous incisional fascia iliaca compartment (FIC) block provides more effective postoperative pain relief (...) with fewer side effects than IV morphine, we performed a prospective, double-blind, randomized study to compare both techniques.Thirty children (ASA physical status I-II) aged 3 mo to 6 yr undergoing a pelvic osteotomy were included in the study. The children were randomized for either morphine IV and placebo (saline) via a FIC catheter (Group M) or placebo (saline) IV and ropivacaine via a FIC catheter (Group R). All patients received general anesthesia using inhaled sevoflurane and IV fentanyl

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2010 EvidenceUpdates

66. Ocular side effects of Topiramate: Frequently asked questions

Ocular side effects of Topiramate: Frequently asked questions The Royal College of Ophthalmologists Ocular side effects of Topiramate- Frequently asked questions 1. What is Topiramate and when is it indicated clinically? Topiramate is a sulfamate-substituted monosaccharide derived from D-fructose. Its is used mainly as an antiepileptic drug both as mono-therapy and as an adjunct in the control of partial and primary generalised epilepsy in adults and children above the age of two 1-3 (...) collected from spontaneous reporting systems have identified one hundred and fifteen cases of ocular side effects which include acute-onset angle closure glaucoma, acute myopia, suprachoriodal effusions, peri-orbital oedema, scleritis, blepharospasm, oculogyric crisis, nystagmus and diplopia 16 . 4. Which patients develop Acute Angle Closure Glaucoma? (AACG) The mean age of occurrence of secondary AACG is 34 years with a range between 3 years and 70 years. The condition has predominantly been reported

2010 Royal College of Ophthalmologists

67. Review of the Ocular side effects of Topiramate

Review of the Ocular side effects of Topiramate RCOphth reference: 2010/PROF/122 Original document 2006 Reviewed October 2010 1 A Review of the Ocular side effects of Topiramate Author: Patrick Watts This manuscript was reviewed by Paediatric Ophthalmology Subcommittee, Royal College of Ophthalmologists Address for Correspondence: Mr Patrick Watts Department of Ophthalmology University Hospital of Wales Cardiff CF14 4XW Telephone: (+44) 2920748583 Fax: (+44) 2920748240 Keywords: Topiramate (...) , Glaucoma RCOphth reference: 2010/PROF/122 Original document 2006 Reviewed October 2010 2 Abstract Acute angle closure glaucoma and visual blurring due to induced myopia have been reported with the use of the antiepileptic drug topiramate. Various hypotheses have been put forward to explain the mechanism of the aforementioned ocular side effects. These presumed ocular side effects of topiramate have included patients treated with other drugs such as serotonin reuptake inhibitors which are also reported

2010 Royal College of Ophthalmologists

68. Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side (...) side-effects after major surgery: a systematic review. Health Technology Assessment 2010; 14(17): 1-94 Authors' conclusions Study found no strong case for routine addition of paracetamol, non-steroidal anti-inflammatory drugs or cyclo-oxygenase inhibitors to patient-controlled administered morphine to reduce morphine consumption and associated adverse effects in the 24 hours following major surgery Project page URL URL for DARE abstract INAHTA brief and checklist Indexing Status Subject indexing

2010 Health Technology Assessment (HTA) Database.

69. Side effects of phytoestrogens: a meta-analysis of randomized trials (PubMed)

Side effects of phytoestrogens: a meta-analysis of randomized trials Phytoestrogens are widely used by postmenopausal women for the treatment of the climacteric syndrome. The risk of adverse effects of this treatment, however, is unknown.Using a fixed-effects model, we performed a meta-analysis of side effects comparing phytoestrogen treatment with placebo or no treatment in randomized controlled trials.We identified 174 randomized controlled trials. Side effects were reported in 92/174 (...) randomized controlled trials with 9629 participants. The overall incidence of side effects in the phytoestrogen and control groups was 2019/5502 (36.7%) and 1824/4806 (38.0%), respectively (P=.2; incidence rate ratio [IRR] 1.01; 95% confidence interval [CI], 0.95-1.08). Comparing various side effect categories, we found significantly higher rates of gastrointestinal side effects among phytoestrogen users (P=.003; IRR 1.28; 95% CI, 1.08-1.50). Gynecological (IRR 0.94; 95% CI, 0.74-1.20), musculoskeletal

2010 EvidenceUpdates

70. Side effects of methylphenidate in childhood cancer survivors: a randomized placebo-controlled trial (PubMed)

Side effects of methylphenidate in childhood cancer survivors: a randomized placebo-controlled trial To investigate the frequency and severity of side effects of methylphenidate among childhood survivors of acute lymphoblastic leukemia and brain tumors and identify predictors of higher adverse effect levels.Childhood cancer survivors (N = 103) identified as having attention and learning problems completed a randomized, double-blind, 3-week, home-crossover trial of placebo, low-dose (...) methylphenidate (0.3 mg/kg; 10 mg twice daily maximum) and moderate-dose methylphenidate (0.6 mg/kg; 20 mg twice daily maximum). Caregivers completed the Barkley Side Effects Rating Scale (SERS) at baseline and each week during the medication trial. Siblings of cancer survivors (N = 49) were recruited as a healthy comparison group.There was a significantly higher number and severity of symptoms endorsed on the SERS when patients were taking moderate dose compared with placebo or low dose, but not low dose

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2009 EvidenceUpdates

71. Risks and side-effects of intrathecal morphine combined with spinal anaesthesia: a meta-analysis

Risks and side-effects of intrathecal morphine combined with spinal anaesthesia: a meta-analysis Risks and side-effects of intrathecal morphine combined with spinal anaesthesia: a meta-analysis Risks and side-effects of intrathecal morphine combined with spinal anaesthesia: a meta-analysis Gehling M, Tryba M CRD summary This review found the use of intrathecal morphine in combination with spinal anaesthesia for post-operative analgesia was associated with an increase in nausea, vomiting (...) and pruritus. The authors' conclusions reflected the evidence presented but some methodological weaknesses mean that the reliability of these conclusions is unclear. Authors' objectives To assess the frequency of side-effects in patients receiving intrathecal morphine in combination with spinal anaesthesia. Searching MEDLINE was searched from inception to 2007; search terms were reported. Reference lists of retrieved articles were also searched for additional studies. It was unclear if any language

2009 DARE.

72. Side effects of phytoestrogens: a meta-analysis of randomized trials

Side effects of phytoestrogens: a meta-analysis of randomized trials Side effects of phytoestrogens: a meta-analysis of randomized trials Side effects of phytoestrogens: a meta-analysis of randomized trials Tempfer CB, Froese G, Heinze G, Bentz EK, Hefler LA, Huber JC CRD summary This review concluded that phytoestrogen supplementation had a safe side-effect profile with moderately increased rates of gastrointestinal side-effects when compared with placebo or no treatment, in women (...) . Supplementation over a period of two years was recommended. This conclusion reflected the evidence presented, but weaknesses in the review methods might limit the reliability of the findings. Authors' objectives To ascertain the incidence of side-effects and adverse occurrences associated with phytoestrogen supplementation in women. Searching PubMed and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched for articles in English. Search terms were reported, but the dates were not. Study

2009 DARE.

73. Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review

Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review Effects and side-effects of surgery for snoring and obstructive sleep apnea: a systematic review Franklin KA, Anttila H, Axelsson S, Gislason T, Maasilta P, Myhre KI, Rehnqvist N CRD summary The review found no evidence of any effect from laser-assisted uvulopalatoplasty or radiofrequency ablation (...) on daytime sleepiness, apnoea, quality of life or snoring; uvula removal carried a high risk of persistent side effects. The authors’ conclusions may require some caution, as there were very few controlled studies (which were possibly underpowered) and findings for snoring were inconsistent. Authors' objectives To determine the benefits and side effects of surgery for snoring and obstructive sleep apnoea in adults. Searching PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) were

2009 DARE.

74. Efficacy, tolerability and side-effect profile of fluvoxamine for major depression: meta-analysis

Efficacy, tolerability and side-effect profile of fluvoxamine for major depression: meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

75. Systematic review and metaanalysis of statins for heterozygous familial hypercholesterolemia in children: evaluation of cholesterol changes and side effects

Systematic review and metaanalysis of statins for heterozygous familial hypercholesterolemia in children: evaluation of cholesterol changes and side effects Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

76. The side effects of morphine and hydromorphone patient-controlled analgesia (PubMed)

The side effects of morphine and hydromorphone patient-controlled analgesia Despite "clinical lore" among health care providers that treatment with hydromorphone results in improved pain control and fewer adverse side effects, morphine continues to be the first-line medication for postoperative patient-controlled analgesia (PCA). In this study, we compared the efficacy and side-effect profiles of morphine and hydromorphone at concentrations producing equivalent drug effect measured by pain (...) score and miosis.We conducted a prospective, randomized, double-blind trial of 50 general and gynecological surgery patients. Subjects were randomly assigned to receive either morphine (1 mg/mL) or hydromorphone (0.2 mg/mL) via PCA after surgery and were followed for a period of 8 h. The primary outcome was nausea. Secondary outcome variables were pruritus, vomiting, sedation, pain report, pupillary miosis, and patient satisfaction.The side effect profile was not different between drugs

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2008 EvidenceUpdates

77. Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects

Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) differing side effects Article Text Therapeutics Haloperidol, risperidone and olanzapine are similarly effective for first-episode non-affective psychosis but have differing side effects Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways. Copyright

2008 Evidence-Based Mental Health

78. Review of side-effect profile of combination ezetimibe and statin therapy in randomized clinical trials (PubMed)

Review of side-effect profile of combination ezetimibe and statin therapy in randomized clinical trials Effective treatment to achieve target lipid parameters in high-risk patients may require combination drug therapies. Concerns regarding risks associated with such combination therapies may limit their use. A systematic overview of randomized controlled trials to assess risks associated with combination statin and ezetimibe therapy was performed. Eighteen trials were identified, including

2008 EvidenceUpdates

79. Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection

Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our (...) . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: eradication therapy supplemented by probiotics increased eradication rates and reduced side effects in H pylori infection

2008 Evidence-Based Medicine (Requires free registration)

80. Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: a systematic review (PubMed)

Antipsychotic-induced extrapyramidal side effects in bipolar disorder and schizophrenia: a systematic review Newer atypical antipsychotics have been reported to cause a lower incidence of extrapyramidal side effects (EPS) than conventional agents. This review is to compare antipsychotic-induced EPS relative to placebo in bipolar disorder (BPD) and schizophrenia.English-language literature cited in Medline was searched with terms antipsychotics, placebo-controlled trial, and bipolar disorder

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2008 EvidenceUpdates