Latest & greatest articles for thyroid

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on thyroid or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on thyroid and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for thyroid

21. Treating subclinical thyroid dysfunction in pregnancy probably has no benefit

Treating subclinical thyroid dysfunction in pregnancy probably has no benefit Treating subclinical thyroid dysfunction in pregnancy probably has no benefit Discover Portal Discover Portal Treating subclinical thyroid dysfunction in pregnancy probably has no benefit Published on 8 August 2017 doi: Testing for and then treating pregnant women with mild or “subclinical” underactive thyroid did not improve pregnancy outcomes, newborn baby outcomes, or the child’s IQ at three to five years (...) . A clearly underactive thyroid (clinical hypothyroidism) in pregnancy has been linked with various adverse outcomes for the mother and baby, including pre-eclampsia, preterm birth, congenital defects and neurodevelopmental delay. This needs treatment. However, there has been debate around the harms and benefits from treating only mildly abnormal blood test results in women who do not show signs of thyroid problems, subclinical hypothyroidism. These two linked trials randomised 1,203 women with borderline

2019 NIHR Dissemination Centre

22. Thyroid hormone treatment does not help adults with mildly abnormal thyroid tests

Thyroid hormone treatment does not help adults with mildly abnormal thyroid tests Thyroid hormone treatment does not help adults with subclinical hypothyroidism Discover Portal Discover Portal Thyroid hormone treatment does not help adults with mildly abnormal thyroid tests Published on 8 January 2019 doi: There appears to be no benefit from treating adults with subclinical hypothyroidism. Treatment has no effect on quality of life or symptoms compared with placebo or no treatment. Thyroid (...) evidence that hormone treatment of subclinical hypothyroidism, gives no measurable benefit either. This may help inform practice, spare patients unnecessary treatment, and save NHS resources. Share your views on the research. Why was this study needed? Hypothyroidism is a condition where the thyroid gland doesn’t produce enough hormones, which can have various underlying causes. Hypothyroidism is characterised by low blood levels of free thyroxine (T4) and high levels of thyroid stimulating hormone

2019 NIHR Dissemination Centre

23. Repeat thyroid function tests for healthy older people are not needed

Repeat thyroid function tests for healthy older people are not needed Repeat thyroid function tests for healthy older people are not needed Discover Portal Discover Portal Repeat thyroid function tests for healthy older people are not needed Published on 2 January 2019 doi: Older adults with normal thyroid function or subclinical thyroid dysfunction show notable long-term stability of their thyroid hormone levels. This suggests that it is safe for GPs not to routinely retest older adults unless (...) they have risk factors or develop clinical symptoms of overt thyroid dysfunction. Over five years, about 0.2% older adults with normal thyroid function will develop overt hypothyroidism and about 3.5% will develop subclinical hypothyroidism. Amongst those with subclinical hypothyroidism, about 2% will develop overt hypothyroidism. The NIHR funded this study as there is a lack of consensus on the relevance of subclinical thyroid dysfunction and the need for repeat testing. This could both reduce

2019 NIHR Dissemination Centre

24. Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery. Full Text available with Trip Pro

Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury in adults undergoing thyroid surgery. Injuries to the recurrent inferior laryngeal nerve (RILN) remain one of the major post-operative complications after thyroid and parathyroid surgery. Damage to this nerve can result in a temporary or permanent palsy, which is associated with vocal cord paresis or paralysis. Visual identification of the RILN is a common procedure to prevent (...) nerve injury during thyroid and parathyroid surgery. Recently, intraoperative neuromonitoring (IONM) has been introduced in order to facilitate the localisation of the nerves and to prevent their injury during surgery. IONM permits nerve identification using an electrode, where, in order to measure the nerve response, the electric field is converted to an acoustic signal.To assess the effects of IONM versus visual nerve identification for the prevention of RILN injury in adults undergoing thyroid

2019 Cochrane

25. Assessment of thyroid mass

Assessment of thyroid mass Assessment of thyroid mass - Differential diagnosis of symptoms | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Assessment of thyroid mass Last reviewed: February 2019 Last updated: January 2019 Summary Thyroid parenchymal expansion can result from diffuse enlargement or infiltration of the thyroid gland or from the presence of one or more thyroid nodules. A thyroid nodule is a discrete lesion distinct from the surrounding (...) thyroid parenchyma. Enlargement of other nearby anatomical structures, such as the parathyroid glands or regional lymph nodes, as well as branchial cleft and thyroglossal duct cysts, may sometimes be confused with thyroid nodules. Thyroid nodules may be palpable at presentation or may be incidentally detected during an imaging procedure (40% are self-identified, 30% are physician-identified, and 30% are incidentally discovered on imaging Mevawalla N, McMullen T, Sidhu S, et al. Presentation

2019 BMJ Best Practice

26. Thyroid Disease

Thyroid Disease New 2018 ACR Appropriateness Criteria ® 1 Thyroid Disease American College of Radiology ACR Appropriateness Criteria ® Thyroid Disease Variant 1: Palpable thyroid nodule. Not goiter. Euthyroid. Initial imaging. Procedure Appropriateness Category Relative Radiation Level US thyroid Usually Appropriate O CT neck with IV contrast May Be Appropriate ??? CT neck without IV contrast May Be Appropriate ??? MRI neck without and with IV contrast Usually Not Appropriate O MRI neck without (...) IV contrast Usually Not Appropriate O I-123 radionuclide uptake and scan neck Usually Not Appropriate ??? I-131 radionuclide uptake and Tc-99m pertechnetate scan neck Usually Not Appropriate ???? CT neck without and with IV contrast Usually Not Appropriate ??? FDG-PET/CT neck Usually Not Appropriate ???? Variant 2: Suspected goiter. Initial imaging. Procedure Appropriateness Category Relative Radiation Level US thyroid Usually Appropriate O CT neck without IV contrast Usually Appropriate ??? CT

2019 American College of Radiology

27. Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma Full Text available with Trip Pro

Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma | From the American Academy of Pediatrics | Pediatrics '); document.write(''); } function OAS_AD(pos) { if (OAS_version >= 11 && typeof(OAS_RICH)!='undefined') { OAS_RICH(pos); } else { OAS_NORMAL(pos); } } //--> Search for this keyword Source User menu Sections Sign up for highlighting editor-chosen (...) studies with the greatest impact on clinical care. Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma In May 2015, the American Academy of Pediatrics endorsed the following publication: Wells SA Jr, Asa SL, Dralle H, et al; The American Thyroid Association Guidelines Task Force on Medullary Thyroid Carcinoma. Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. Thyroid . 2015;25(6). doi: . All statements

2019 American Academy of Pediatrics

28. Management Guidelines for Children With Thyroid Nodules and Differentiated Thyroid Cancer

Management Guidelines for Children With Thyroid Nodules and Differentiated Thyroid Cancer Management Guidelines for Children With Thyroid Nodules and Differentiated Thyroid Cancer | From the American Academy of Pediatrics | Pediatrics '); document.write(''); } function OAS_AD(pos) { if (OAS_version >= 11 && typeof(OAS_RICH)!='undefined') { OAS_RICH(pos); } else { OAS_NORMAL(pos); } } //--> Search for this keyword Source User menu Sections Sign up for highlighting editor-chosen studies (...) with the greatest impact on clinical care. Management Guidelines for Children With Thyroid Nodules and Differentiated Thyroid Cancer In July 2015, the American Academy of Pediatrics endorsed the following publication: Francis GL, Waguespack SG, Bauer AJ, et al; The American Thyroid Association Guidelines Task Force on Pediatric Thyroid Cancer. Management guidelines for children with thyroid nodules and differentiated thyroid cancer. Thyroid . 2015;25(7):716–759. doi: 10.1089/thy.2014.0460. All statements

2019 American Academy of Pediatrics

29. Thyroid carcinomas in hyperfunctioning thyroid nodules: systematic review and a meta analysis

Thyroid carcinomas in hyperfunctioning thyroid nodules: systematic review and a meta analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address

2019 PROSPERO

30. A prognostic role for non-thyroidal illness syndrome in chronic renal failure: a systematic review and meta-analysis

A prognostic role for non-thyroidal illness syndrome in chronic renal failure: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence

2019 PROSPERO

31. The effect of thyroid autoimmunity on IVF/ICSI outcomes

The effect of thyroid autoimmunity on IVF/ICSI outcomes Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne") for correspondence: Organisation web address: Timing and effect measures Timing

2019 PROSPERO

32. Thyroid autoimmunity and miscarriage in pregnant women

Thyroid autoimmunity and miscarriage in pregnant women Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith

2019 PROSPERO

33. Do computer-aided diagnosis systems add any accuracy in diagnosing malignant thyroid nodules on ultrasonography? A systematic review and meta-analysis

Do computer-aided diagnosis systems add any accuracy in diagnosing malignant thyroid nodules on ultrasonography? A systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2019 PROSPERO

34. Effects and side effects of different degrees of postoperative thyroid hormone suppression therapy in differentiated thyroid cancer patients.

Effects and side effects of different degrees of postoperative thyroid hormone suppression therapy in differentiated thyroid cancer patients. Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2019 PROSPERO

35. The association of gestational thyroid function and thyroid autoimmunity with gestational hypertension and preeclampsia

The association of gestational thyroid function and thyroid autoimmunity with gestational hypertension and preeclampsia Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

36. Effect of levothyroxine on pregnancy outcomes in women with thyroid autoimmunity: a systematic review with meta-analysis and trial sequential analysis

Effect of levothyroxine on pregnancy outcomes in women with thyroid autoimmunity: a systematic review with meta-analysis and trial sequential analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2019 PROSPERO

37. Circulating irisin level in patients with abnormal thyroid function: a systematic review and meta-analysis

Circulating irisin level in patients with abnormal thyroid function: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2019 PROSPERO

38. Postnatal thyroid hormones for preterm infants with transient hypothyroxinemia: a systematic review and meta-analysis

Postnatal thyroid hormones for preterm infants with transient hypothyroxinemia: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated

2019 PROSPERO

39. Outcomes of repeat fine needle aspiration biopsy for Bethesda III thyroid nodules: a systematic review and meta-analysis

Outcomes of repeat fine needle aspiration biopsy for Bethesda III thyroid nodules: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

40. Impact of ultrasound-guided fine needle aspiration cytology (UGFNAC) for the diagnosis of thyroid nodules(TN): a systematic review protocol

Impact of ultrasound-guided fine needle aspiration cytology (UGFNAC) for the diagnosis of thyroid nodules(TN): a systematic review protocol Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO