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Latest & greatest articles for traumatic brain injury
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on traumatic brain injury or other clinical topics then use Trip today.
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Rehabilitation of Persons With TraumaticBrainInjury NIH Consensus Statement Volume 16, Number 1 October 26–28, 1998 Rehabilitation of Persons with TraumaticBrainInjury NATIONAL INSTITUTES OF HEALTH Office of the Director About the NIH Consensus Development Program NIH Consensus Development Conferences are convened to evalu ate available scientific information and resolve safety and efficacy issues related to a biomedical technology. The resultant NIH Consensus Statements are intended (...) the remain der of the second day and morning of the third. This statement is an independent report of the consensus panel and is not a policy statement of the NIH or the Federal Government. Reference Information For making bibliographic reference to this consensus statement, it is recommended that the following format be used, with or without source abbreviations, but without authorship attribution: Rehabilitation of Persons with TraumaticBrainInjury. NIH Consens Statement 1998 Oct 26–28; 16(1): 1–41
Treatment of traumaticbraininjury with moderate hypothermia. Traumaticbraininjury initiates several metabolic processes that can exacerbate the injury. There is evidence that hypothermia may limit some of these deleterious metabolic responses.In a randomized, controlled trial, we compared the effects of moderate hypothermia and normothermia in 82 patients with severe closed head injuries (a score of 3 to 7 on the Glasgow Coma Scale). The patients assigned to hypothermia were cooled to 33 (...) interval, 0.1 to 0.9 at both intervals), although not at 12 months (risk ratio, 0.3; 95 percent confidence interval, 0.1 to 1.0).Treatment with moderate hypothermia for 24 hours in patients with severe traumaticbraininjury and coma scores of 5 to 7 on admission hastened neurologic recovery and may have improved the outcome.
Corticosteroids in acute traumaticbraininjury: systematic review of randomised controlled trials. To quantify the effectiveness and safety of corticosteroids in the treatment of acute traumaticbrain injury.Systematic review of randomised controlled trials of corticosteroids in acute traumaticbraininjury. Summary odds ratios were estimated as an inverse variance weighted average of the odds ratios for each study.Randomised trials available by March 1996.The included trials with outcome data (...) it was 1.05 (0.44 to 2.52). With only those trials with the best quality of concealment of allocation, the pooled odds ratio estimates for death and death or disability became closer to unity.This systematic review of randomised controlled trials of corticosteroids in acute traumaticbraininjury shows that there remains considerable uncertainty over their effects. Neither moderate benefits nor moderate harmful effects can be excluded. The widely practicable nature of the drugs and the importance