Latest & greatest articles for acetaminophen

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Top results for acetaminophen

81. Pre-emptive Oral Non-Steroidal Anti-Inflammatory Drugs or Acetaminophen for Knee Arthroscopy: A Rapid Review

Pre-emptive Oral Non-Steroidal Anti-Inflammatory Drugs or Acetaminophen for Knee Arthroscopy: A Rapid Review Pre-emptive oral non-steroidal anti-inflammatory drugs or acetaminophen for knee arthroscopy: a rapid review Pre-emptive oral non-steroidal anti-inflammatory drugs or acetaminophen for knee arthroscopy: a rapid review Health Quality Ontario Citation Health Quality Ontario. Pre-emptive oral non-steroidal anti-inflammatory drugs or acetaminophen for knee arthroscopy: a rapid review (...) . Toronto: Health Quality Ontario (HQO). Rapid Review. 2014 Authors' conclusions Based on 2 RCTs, both with limitations due to risk of bias, there were inconsistent results regarding the effectiveness of pre-emptive oral celecoxib, a selective COX-2 inhibitor NSAID, for post-operative pain control in patients undergoing knee arthroscopy. No evidence was identified that evaluated the oral pre-emptive use of acetaminophen or conventional NSAIDs for post-operative pain control in patients undergoing knee

2014 Health Technology Assessment (HTA) Database.

82. Codeine, alone and with paracetamol (acetaminophen), for cancer pain. Full Text available with Trip Pro

Codeine, alone and with paracetamol (acetaminophen), for cancer pain. Pain is very common in patients with cancer. Opioid analgesics, including codeine, play a significant role in major guidelines on the management of cancer pain, particularly for mild to moderate pain. Codeine is widely available and inexpensive, which may make it a good choice, especially in low-resource settings. Its use is controversial, in part because codeine is not effective in a minority of patients who cannot convert (...) it to its active metabolite (morphine), and also because of concerns about potential abuse, and safety in children.To determine the efficacy and safety of codeine used alone or in combination with paracetamol for relieving cancer pain.We searched the Cochrane Central Register of Controlled Trials (CENTRAL; The Cochrane Library 2014, Issue 2), MEDLINE and EMBASE from inception to 5 March 2014, supplemented by searches of clinical trial registries and screening of the reference lists of the identified

2014 Cochrane

83. Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone

* Associated Topics Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone Ferne Kraglund DDS . Overview Systematic Review Conclusion Current evidence suggests that a combination of acetaminophen, also known as paracetamol, and a nonsteroidal anti-inflammatory drug (NSAID) may offer superior analgesia than does either drug alone. Critical Summary Assessment The authors of this high-quality review of 21 double-masked randomized controlled (...) Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all

2014 ADA Center for Evidence-Based Dentistry

84. Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone

* Associated Topics Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone Ferne Kraglund DDS . Overview Systematic Review Conclusion Current evidence suggests that a combination of acetaminophen, also known as paracetamol, and a nonsteroidal anti-inflammatory drug (NSAID) may offer superior analgesia than does either drug alone. Critical Summary Assessment The authors of this high-quality review of 21 double-masked randomized controlled (...) Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all

2014 ADA Center for Evidence-Based Dentistry

85. Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone

* Associated Topics Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone Ferne Kraglund DDS . Overview Systematic Review Conclusion Current evidence suggests that a combination of acetaminophen, also known as paracetamol, and a nonsteroidal anti-inflammatory drug (NSAID) may offer superior analgesia than does either drug alone. Critical Summary Assessment The authors of this high-quality review of 21 double-masked randomized controlled (...) Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all

2014 ADA Center for Evidence-Based Dentistry

86. For Post-Dental Extraction Pain, Co-therapy with Acetaminophen and Ibuprofen is More Effective in Pain Management than Acetaminophen or Ibuprofen Alone

For Post-Dental Extraction Pain, Co-therapy with Acetaminophen and Ibuprofen is More Effective in Pain Management than Acetaminophen or Ibuprofen Alone UTCAT2734, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title For Post-Dental Extraction Pain, Co-therapy with Acetaminophen and Ibuprofen is More Effective in Pain Management than Acetaminophen or Ibuprofen Alone Clinical Question In patients following a dental extraction (...) is the post-operative administration of combined acetaminophen and ibuprofen better than therapy with acetaminophen or ibuprofen alone for pain management? Clinical Bottom Line The post-operative use combined acetaminophen and ibuprofen provides superior pain relief compared to acetaminophen or ibuprofen alone. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Bailey/2013 Patient Group 2,241 patients ages 16-65

2014 UTHSCSA Dental School CAT Library

87. Tramadol/Acetaminophen Tablets Provide Rapid, Effective, and Dose-Dependent Analgesia Following Dental Surgery

Tramadol/Acetaminophen Tablets Provide Rapid, Effective, and Dose-Dependent Analgesia Following Dental Surgery UTCAT2725, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Tramadol/Acetaminophen Tablets Provide Rapid, Effective, and Dose-Dependent Analgesia Following Dental Surgery Clinical Question Following dental surgery, does Tramadol provide adequate analgesia when compared to hydrocodone/APAP or codeine/APAP (...) combination drug preparations? Clinical Bottom Line Tramadol/Acetaminophen 75/650mg tablets provide effective, rapid ( Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Jung/2004 128 healthy adults undergoing extraction of > or = 1 impacted 3rd molars Randomized Controlled Trial Key results Tr/APAP 75/650mg and Co/APAP/Ibuprofen 20/500/400mg mean total pain relief and the sum of pain intensity difference were

2014 UTHSCSA Dental School CAT Library

88. Effect of intravenous paracetamol on postoperative morphine requirements in neonates and infants undergoing major noncardiac surgery: a randomized controlled trial

Effect of intravenous paracetamol on postoperative morphine requirements in neonates and infants undergoing major noncardiac surgery: a randomized controlled trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2014 PedsCCM Evidence-Based Journal Club

89. Paracetamol overdose

Paracetamol overdose PARACETAMOL OVERDOSE IN PREGNANCY 0344 892 0909 PARACETAMOL OVERDOSE IN PREGNANCY (Date of issue: May 2018 , Version: 1.3 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . Summary There are limited published data on fetal outcomes following paracetamol overdose during human pregnancy, however (...) the information available does not suggest an increased risk of congenital malformation or fetal loss in the absence of severe maternal toxicity. There is evidence that the fetal liver begins to metabolise paracetamol from 18 weeks gestation onwards, therefore the fetus may also be at risk for hepatotoxicity following maternal paracetamol overdose at and beyond this stage. Maternal treatment of paracetamol overdose should be as for the non-pregnant patient. There is evidence linking a delay in treating

2014 UK Teratology Information Service

90. Paracetamol

Paracetamol ‘THERAPEUTIC’ USE OF PARACETAMOL IN PREGNANCY 0344 892 0909 ‘THERAPEUTIC’ USE OF PARACETAMOL IN PREGNANCY (Date of issue: March 2017 , Version: 1.8 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . A corresponding patient information leaflet on is available at . Summary Paracetamol is an antipyretic (...) analgesic indicated for the treatment of mild to moderate pain and pyrexia. For the purpose of this monograph ‘therapeutic’ use of oral paracetamol is regarded as 500-1000mg up to four times a day, with a maximum dose of 4g within a 24-hour period. Where this dose is exceeded or other factors such as prolonged use or low maternal weight are present, an assessment for paracetamol overdose may need to be considered. Please refer to our monograph ‘Paracetamol overdose in pregnancy’ for further information

2014 UK Teratology Information Service

91. Pre-emptive Oral Non-Steroidal Anti-Inflammatory Drugs or Acetaminophen for Knee Arthroscopy

antiinflammatory agent/ use emez or exp salicylic acid derivative/ use emez or exp prostaglandin synthase inhibitor/ use emez 1692023 11 (NSAID* or ((non-steroidal or nonsteroidal) adj3 agent*) or antiinflammator* or anti inflammator* or ibuprofen or aspirin or tylenol or n-acetyl-p-aminophenol or parcetamol or anacin or acamol or acetaco or apap or acetaminophen or acetominophen or acephen or acetamidophenol or hydroxyacetanilide or panadol or algotropyl or datril or ip 82 or ip82 or ibumetin or motrin (...) Pre-emptive Oral Non-Steroidal Anti-Inflammatory Drugs or Acetaminophen for Knee Arthroscopy Pre-emptive Oral Non-Steroidal Anti-Inflammatory Drugs or Acetaminophen for Knee Arthroscopy: A Rapid Review. August 2014; pp. 1–18 Pre-emptive Oral Non-Steroidal Anti- Inflammatory Drugs or Acetaminophen for Knee Arthroscopy: A Rapid Review Health Quality Ontario August 2014 Evidence Development and Standards Branch at Health Quality Ontario Pre-emptive Oral Non-Steroidal Anti-Inflammatory Drugs

2014 Health Quality Ontario

92. Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial. (Abstract)

Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial. Regular paracetamol is the recommended first-line analgesic for acute low-back pain; however, no high-quality evidence supports this recommendation. We aimed to assess the efficacy of paracetamol taken regularly or as-needed to improve time to recovery from pain, compared with placebo, in patients with low-back pain.We did a multicentre, double-dummy, randomised, placebo controlled trial across 235 (...) primary care centres in Sydney, Australia, from Nov 11, 2009, to March 5, 2013. We randomly allocated patients with acute low-back pain in a 1:1:1 ratio to receive up to 4 weeks of regular doses of paracetamol (three times per day; equivalent to 3990 mg paracetamol per day), as-needed doses of paracetamol (taken when needed for pain relief; maximum 4000 mg paracetamol per day), or placebo. Randomisation was done according to a centralised randomisation schedule prepared by a researcher who

2014 Lancet Controlled trial quality: predicted high

93. Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial. Full Text available with Trip Pro

Reduction of adverse effects from intravenous acetylcysteine treatment for paracetamol poisoning: a randomised controlled trial. Paracetamol poisoning is common worldwide. It is treated with intravenous acetylcysteine, but the standard regimen is complex and associated with frequent adverse effects related to concentration, which can cause treatment interruption. We aimed to ascertain whether adverse effects could be reduced with either a shorter modified acetylcysteine schedule, antiemetic (...) pretreatment, or both.We undertook a double-blind, randomised factorial study at three UK hospitals, between Sept 6, 2010, and Dec 31, 2012. We randomly allocated patients with acute paracetamol overdose to either the standard intravenous acetylcysteine regimen (duration 20·25 h) or a shorter (12 h) modified protocol, with or without intravenous ondansetron pretreatment (4 mg). Masking was achieved by infusion of 5% dextrose (during acetylcysteine delivery) or saline (for antiemetic pretreatment

2014 Lancet Controlled trial quality: predicted high

94. Randomised controlled trial: Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care

Randomised controlled trial: Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser (...) with paracetamol in patients with acute respiratory tract infections in primary care Article Text Therapeutics Randomised controlled trial Neither ibuprofen nor steam improves symptom control compared with paracetamol in patients with acute respiratory tract infections in primary care Philipp Schuetz Statistics from Altmetric.com Commentary on: Little P , Moore M , Kelly J , et al . Ibuprofen, paracetamol, and steam for patients with respiratory tract infections in primary care: pragmatic randomised factorial

2014 Evidence-Based Medicine

95. Intravenous acetaminophen for acute postoperative pain in adults

Intravenous acetaminophen for acute postoperative pain in adults Intravenous acetaminophen for acute postoperative pain in adults Intravenous acetaminophen for acute postoperative pain in adults Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Intravenous acetaminophen for acute postoperative pain in adults. Lansdale: HAYES, Inc.. Healthcare Technology Brief (...) the medications acetaminophen, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), selective inhibitors of cyclo-oxygenase-2, ketamine, aspirin, and nonpharmacologic therapies. Opioids have side effects that can be dose limiting such as nausea, vomiting, constipation, decreased gastrointestinal motility, urinary retention, sedation, confusion, and respiratory depression. NSAIDs are contraindicated in patients with renal impairment and may cause bleeding, platelet dysfunction, renal toxicity

2014 Health Technology Assessment (HTA) Database.

96. Acetaminophen (paracetamol) for the common cold in adults. (Abstract)

Acetaminophen (paracetamol) for the common cold in adults. Acetaminophen is frequently prescribed for treating patients with the common cold, but there is little evidence as to whether it is effective.To determine the efficacy and safety of acetaminophen in the treatment of the common cold in adults.We searched CENTRAL 2013, Issue 1, Ovid MEDLINE (1950 to January week 5, 2013), EMBASE (1980 to February 2013), CINAHL (1982 to February 2013) and LILACS (1985 to February 2013).We included (...) randomised controlled trials (RCTs) comparing acetaminophen to placebo or no treatment in adults with the common cold. Studies were included if the trials used acetaminophen as one ingredient of a combination therapy. We excluded studies in which the participants had complications. Primary outcomes included subjective symptom score and duration of common cold symptoms. Secondary outcomes were overall well being, adverse events and financial costs.Two review authors independently screened studies

2013 Cochrane

97. Intravenous or rectal acetaminophen for post-operative pain

Intravenous or rectal acetaminophen for post-operative pain Intravenous or rectal acetaminophen for post-operative pain Intravenous or rectal acetaminophen for post-operative pain Mitchell MD, Umscheid CA Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell MD, Umscheid CA. Intravenous or rectal acetaminophen for post-operative pain (...) . Philadelphia: Center for Evidence-based Practice (CEP). 2013 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Humans; Pain, Postoperative Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania Health System, 3535 Market St. Suite 50, Philadelphia PA 19104

2013 Health Technology Assessment (HTA) Database.

98. King`s College Hospital Criteria for non-acetaminophen induced acute liver failure in an international cohort of children Full Text available with Trip Pro

King`s College Hospital Criteria for non-acetaminophen induced acute liver failure in an international cohort of children To validate King's College Hospital criteria (KCHC) in children with non-acetaminophen induced pediatric acute liver failure (PALF) and to determine whether re-optimizing the KCHC would improve predictive accuracy.We used the PALF study group database. Primary outcomes were survival without liver transplantation vs death at 21 days following enrollment. Classification

2013 EvidenceUpdates

99. For Patients With Dental Pain, Combination Therapy With Ibuprofen And Acetaminophen Is More Effective In Producing Analgesia Than Monotherapy With Ibuprofen Alone

For Patients With Dental Pain, Combination Therapy With Ibuprofen And Acetaminophen Is More Effective In Producing Analgesia Than Monotherapy With Ibuprofen Alone UTCAT2379, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title For Patients With Dental Pain, Combination Therapy With Ibuprofen And Acetaminophen Is More Effective In Producing Analgesia Than Monotherapy With Ibuprofen Alone Clinical Question In patients (...) with inflammatory pain, does the combination of ibuprofen and acetaminophen compared to ibuprofen alone produce greater analgesia? Clinical Bottom Line Combination therapy with ibuprofen and acetaminophen produces greater analgesia than ibuprofen alone in patients with inflammatory pain. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Daniels/2011 678 patients at least 16 years old with at least 3 impacted 3rd

2013 UTHSCSA Dental School CAT Library

100. Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses. Full Text available with Trip Pro

Long term effect of reduced pack sizes of paracetamol on poisoning deaths and liver transplant activity in England and Wales: interrupted time series analyses. To assess the long term effect of United Kingdom legislation introduced in September 1998 to restrict pack sizes of paracetamol on deaths from paracetamol poisoning and liver unit activity.Interrupted time series analyses to assess mean quarterly changes from October 1998 to the end of 2009 relative to projected deaths without (...) the legislation based on pre-legislation trends.Mortality (1993-2009) and liver unit activity (1995-2009) in England and Wales, using information from the Office for National Statistics and NHS Blood and Transplant, respectively.Residents of England and Wales.Suicide, deaths of undetermined intent, and accidental poisoning deaths involving single drug ingestion of paracetamol and paracetamol compounds in people aged 10 years and over, and liver unit registrations and transplantations for paracetamol induced

2013 BMJ