Latest & greatest articles for acetaminophen

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Top results for acetaminophen

141. Ibuprofen was more effective than codeine or acetaminophen for musculoskeletal pain in children

Ibuprofen was more effective than codeine or acetaminophen for musculoskeletal pain in children Ibuprofen was more effective than codeine or acetaminophen for musculoskeletal pain in children | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Ibuprofen was more effective than codeine or acetaminophen for musculoskeletal pain in children Article Text Therapeutics Ibuprofen was more effective than codeine or acetaminophen for musculoskeletal

2008 Evidence-Based Medicine

142. Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. (Abstract)

Association between paracetamol use in infancy and childhood, and risk of asthma, rhinoconjunctivitis, and eczema in children aged 6-7 years: analysis from Phase Three of the ISAAC programme. Exposure to paracetamol during intrauterine life, childhood, and adult life may increase the risk of developing asthma. We studied 6-7-year-old children from Phase Three of the International Study of Asthma and Allergies in Childhood (ISAAC) programme to investigate the association between paracetamol (...) consumption and asthma.As part of Phase Three of ISAAC, parents or guardians of children aged 6-7 years completed written questionnaires about symptoms of asthma, rhinoconjunctivitis, and eczema, and several risk factors, including the use of paracetamol for fever in the child's first year of life and the frequency of paracetamol use in the past 12 months. The primary outcome variable was the odds ratio (OR) of asthma symptoms in these children associated with the use of paracetamol for fever in the first

2008 Lancet

143. Acetaminophen use during pregnancy: effects on risk for congenital abnormalities (Abstract)

Acetaminophen use during pregnancy: effects on risk for congenital abnormalities We evaluated if acetaminophen, one of the most frequently used drugs among pregnant women is associated with an increased prevalence of congenital abnormalities.We selected 88,142 pregnant women and their liveborn singletons from the Danish National Birth Cohort who had information on acetaminophen use during the first trimester of pregnancy. We used the National Hospital Registry to identify 3784 (4.3%) children (...) from the cohort diagnosed with 5847 congenital abnormalities.Children exposed to acetaminophen during the first trimester of pregnancy (n = 26,424) did not have an increased prevalence of congenital abnormalities (hazard ratio = 1.01, 0.93-1.08) compared with nonexposed children (n = 61,718). No association was found between congenital abnormalities and duration of use during the first trimester. Increased prevalence was not observed for specific abnormalities, except for "medial cysts, fistula

2008 EvidenceUpdates

144. Should ondanestron be used as the first-line anti-emetic in paracetamol overdose

effective than other anti-emetics in this patient group and wonder whether this should be your first-line option. Search Strategy Medline 1950 to August week 5 2007 (OVID interface) The Cochrane Library Issue 3 2007 Medline: (ondansetron.mp or exp Ondansetron/) AND (paracetamol.mp or exp Acetaminophen/), 20 records. Cochrane: ondanstron (ti, ab.kw.) AND paracetamol (ti, ab.kw.)—nine records; ondansetron (ti, ab.kw.) AND acetaminophen (ti, ab.kw.)—11 records. Search Outcome None of the papers identified (...) Should ondanestron be used as the first-line anti-emetic in paracetamol overdose BestBets: Should ondanestron be used as the first-line anti-emetic in paracetamol overdose Should ondanestron be used as the first-line anti-emetic in paracetamol overdose Report By: Emma Jenkinson, - Foundation Year One Search checked by Nigel Langford, - Consultant Institution: City Hospital, Birmingham, UK Date Submitted: 25th January 2008 Date Completed: 25th January 2008 Last Modified: 25th January 2008 Status

2008 BestBETS

145. Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial. Full Text available with Trip Pro

Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): randomised controlled trial. To investigate whether paracetamol (acetaminophen) plus ibuprofen are superior to either drug alone for increasing time without fever and the relief of fever associated discomfort in febrile children managed at home.Individually randomised, blinded, three arm trial.Primary care and households in England.Children aged between 6 months and 6 years with axillary temperatures of at least 37.8 (...) degrees C and up to 41.0 degrees C.Advice on physical measures to reduce temperature and the provision of, and advice to give, paracetamol plus ibuprofen, paracetamol alone, or ibuprofen alone.Primary outcomes were the time without fever (<37.2 degrees C) in the first four hours after the first dose was given and the proportion of children reported as being normal on the discomfort scale at 48 hours. Secondary outcomes were time to first occurrence of normal temperature (fever clearance), time without

2008 BMJ Controlled trial quality: predicted high

146. Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): economic evaluation of a randomised controlled trial. Full Text available with Trip Pro

Paracetamol plus ibuprofen for the treatment of fever in children (PITCH): economic evaluation of a randomised controlled trial. To estimate the cost to the NHS and to parents and carers of treating febrile preschool children with paracetamol, ibuprofen, or both, and to compare these costs with the benefits of each treatment regimen.Cost consequences analysis and cost effectiveness analysis conducted as part of a three arm, randomised controlled trial.Children between the ages of 6 months and 6 (...) of the estimates of cost and some outcomes. At 48 hours, cost to the NHS was pound11.33 for paracetamol, pound8.49 for ibuprofen, and pound8.16 for both drugs. By day 5 these costs rose to pound19.63, pound18.36, and pound13.92 respectively. For parents and carers, the 48 hour costs were pound23.86 for paracetamol, pound20.60 for ibuprofen, and pound25.07 for both, and the day 5 costs were pound26.35, pound29.90, and pound24.02 respectively. Outcomes measured at 48 hours and 5 days were inconclusive because

2008 BMJ Controlled trial quality: uncertain

147. Guidelines for the management of paracetamol poisoning in Australia and New Zealand - explanation and elaboration Full Text available with Trip Pro

the development of the new guidelines poster only; they had no role in the preparation, review or approval of this manuscript. Competing interests: Frank Daly, John Fountain and Lindsay Murray each received a small honorarium from GSK for attending a half-day round-table meeting to discuss the content and scope of the poster (“Guidelines for the management of paracetamol overdose”) upon which this article is based. Buckley N, Eddleston M. Paracetamol (acetaminophen) poisoning. Clin Evid 2005; (14): 1738-1744 (...) in severe acute paracetamol poisoning. Hum Toxicol 1986; 5: 179-182. Reid D, Hazell W. Paracetamol poisoning: which nomogram should we use? Emerg Med (Fremantle) 2003; 15: 486-496. Prescott LF, Illingworth RN, Critchley JA, et al. Intravenous N -acetylcystine: the treatment of choice for paracetamol poisoning. Br Med J 1979; 2: 1097-1100. Smilkstein MJ, Knapp GL, Kulig KW, Rumack BH. Efficacy of oral N -acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study

2008 MJA Clinical Guidelines

148. A systematic review of paracetamol for non-specific low back pain

A systematic review of paracetamol for non-specific low back pain Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

149. A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery (Abstract)

A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery Narcotics are used extensively in outpatient general surgery but are often poorly tolerated with variable efficacy. Acetaminophen combined with NSAIDs is a possible alternative. The objective of this study was to compare the efficacy of acetaminophen, codeine, and caffeine (Tylenol No. 3) with acetaminophen and ibuprofen for management of pain (...) after outpatient general surgery procedures.A double-blind randomized controlled trial was performed in patients undergoing outpatient inguinal/umbilical/ventral hernia repair or laparoscopic cholecystectomy. Patients were randomized to receive acetaminophen plus codeine plus caffeine (Tylenol No. 3) or acetaminophen plus ibuprofen (AcIBU) 4 times daily for 7 days or until pain-free. Pain intensity, measured four times daily by visual analogue scale, was the primary outcome. Secondary end points

2008 EvidenceUpdates Controlled trial quality: predicted high

150. Tramadol hydrochloride /acetaminophen

Tramadol hydrochloride /acetaminophen Common Drug Review CEDAC Meeting – April 18, 2007 Page 1 of 2 Notice of CEDAC Final Recommendation – May 17, 2007 CEDAC FINAL RECOMMENDATION and REASONS for RECOMMENDATION TRAMADOL HYDROCHLORIDE/ACETAMINOPHEN (Tramacet ™ – Janssen-Ortho Inc.) Description: Tramacet ™ is a fixed dose combination of tramadol hydrochloride, a synthetic opioid analgesic, and acetaminophen. It is approved for the short term (five days or less) management of acute pain. Dosage (...) Forms: Tablets contain 37.5 mg of tramadol hydrochloride and 325 mg of acetaminophen. The recommended dose of Tramacet ™ is one to two tablets every four to six hours, as needed, for pain relief, to a maximum of eight tablets per day. Recommendation: The Canadian Expert Drug Advisory Committee (CEDAC) recommends that Tramacet ™ not be listed. Reasons for the Recommendation: 1. There is insufficient evidence that Tramacet ™ provides a therapeutic advantage over less expensive analgesics

2007 Canadian Agency for Drugs and Technologies in Health - Common Drug Review

151. Paracetamol, non-steroidal anti-inflammatory drugs, and combination treatment did not differ for pain relief after musculoskeletal injury

Paracetamol, non-steroidal anti-inflammatory drugs, and combination treatment did not differ for pain relief after musculoskeletal injury Paracetamol, non-steroidal anti-inflammatory drugs, and combination treatment did not differ for pain relief after musculoskeletal injury | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) , please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Paracetamol, non-steroidal anti-inflammatory drugs, and combination treatment did not differ for pain relief after

2007 Evidence-Based Nursing

152. Acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization Full Text available with Trip Pro

Acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization Acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization Acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunization Manley J, Taddio A CRD summary This review investigated use of acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunisation. The authors concluded (...) that acetaminophen and ibuprofen may prevent adverse events in young infants receiving diphtheria-tetanus toxoids-whole pertussis vaccine. No benefits were demonstrated for the diphtheria-tetanusoxides acellular pertussis vaccine. The conclusions may not be reliable due to methodological limitations. Authors' objectives To evaluate prophylactic use of acetaminophen and ibuprofen for prevention of adverse reactions associated with childhood immunisation. Searching MEDLINE (1966 to February 2007), PubMed (1966

2007 DARE.

153. Prednisolone plus paracetamol (acetaminophen) was as effective as indomethacin plus paracetamol but had fewer adverse effects in acute gout-like arthritis

Prednisolone plus paracetamol (acetaminophen) was as effective as indomethacin plus paracetamol but had fewer adverse effects in acute gout-like arthritis Prednisolone plus paracetamol (acetaminophen) was as effective as indomethacin plus paracetamol but had fewer adverse effects in acute gout-like arthritis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time (...) . To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Prednisolone plus paracetamol (acetaminophen) was as effective as indomethacin

2007 Evidence-Based Medicine

154. Drugs - Paracetamol Oral Solution Suspension

Drugs - Paracetamol Oral Solution Suspension Drugs October 2006 Page 1 of 1 Drugs Paracetamol Oral Solution/ Suspension PAR PRESENTATION A solution or suspension containing paracetamol 120 milligrams in 5ml or paracetamol 250 milligrams in 5 ml. ACTIONS Analgesic (pain relieving) and antipyretic (temperature reducing) drug. DOSAGE AND ADMINISTRATION Route: Oral (5ml syringe). Route: Oral (5ml syringe). ADDITIONAL INFORMATION A febrile child should not be left at home except where a full (...) assessment has been carried out, the child has no apparent serious underlying illness and the child is referred to the General Practitioner with the full consent of the parent (or carer). INDICATIONS Relief of mild to moderate pain and/or high temperature. Intended primarily for use in children but may also be applicable to adults. CONTRA-INDICATIONS Known allergy to paracetamol containing products. If a product containing paracetamol (e.g. Calpol, Disprol) has been given within the last four hours

2007 Joint Royal Colleges Ambulance Liaison Committee

155. Acetaminophen poisoning: an evidence-based consensus guideline for out-of-hospital management.

Acetaminophen poisoning: an evidence-based consensus guideline for out-of-hospital management. Guidelines and Measures | Agency for Healthcare Research & Quality HHS.gov Search ahrq.gov Search ahrq.gov Menu Topics A - Z Healthcare Delivery Latest available findings on quality of and access to health care Searchable database of AHRQ Grants, Working Papers & HHS Recovery Act Projects AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund You are here Guidelines and Measures

2006 American Association of Poison Control Centers

156. Review: paracetamol reduces pain in osteoarthritis but is less effective than NSAIDs Full Text available with Trip Pro

, ARNP Statistics from Altmetric.com Zhang W, Jones A, Doherty M. Does paracetamol (acetaminophen) reduce the pain of osteoarthritis? A meta-analysis of randomised controlled trials. Ann Rheum Dis 2004 ; 63 : 901 –7. Q Is paracetamol efficacious for treatment of osteoarthritis (OA)? METHODS Data sources: Medline, CINAHL, EMBASE/Excerpta Medica, Scientific Citation Index, and Cochrane Library (up to July 2003); reference lists; and conference abstracts from international societies of rheumatology (...) Review: paracetamol reduces pain in osteoarthritis but is less effective than NSAIDs Review: paracetamol reduces pain in osteoarthritis but is less effective than NSAIDs | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional

2006 Evidence-Based Mental Health

157. Review: no evidence exists that paracetamol and ibuprofen differ for short term pain relief or safety in children, but ibuprofen more effectively reduces fever Full Text available with Trip Pro

pain relief or safety in children, but ibuprofen more effectively reduces fever Article Text Treatment Review: no evidence exists that paracetamol and ibuprofen differ for short term pain relief or safety in children, but ibuprofen more effectively reduces fever Free Jeanette Robertson , RN, MSc, FRCNA Statistics from Altmetric.com Perrott DA, Piira T, Goodenough B, et al . Efficacy and safety of acetaminophen vs ibuprofen for treating children’s pain or fever: a meta-analysis. Arch Pediatr Adolesc (...) Med 2004 ; 158 : 521 –6. Q What is the relative effectiveness and safety of paracetamol (acetaminophen) and ibuprofen for short term treatment of pain and fever in children? METHODS Data sources: Medline, CINAHL, EMBASE/Excerpta Medica, Cochrane Library , Biological Abstracts, Biological Abstracts/RRM, Dissertation Abstracts International, Evidence-Based Medicine Reviews (EBMR) Best Evidence, EBMR Database of Abstracts of Reviews of Effectiveness, ERIC, Expanded Academic ASAP, General Science

2006 Evidence-Based Mental Health

158. Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. Full Text available with Trip Pro

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. During a clinical trial of a novel hydrocodone/acetaminophen combination, a high incidence of serum alanine aminotransferase (ALT) elevations was observed.To characterize the incidence and magnitude of ALT elevations in healthy participants receiving 4 g of acetaminophen daily, either alone or in combination with selected opioids, as compared with participants treated (...) with placebo.A randomized, single-blind, placebo-controlled, 5-treatment, parallel-group, inpatient, diet-controlled (meals provided), longitudinal study of 145 healthy adults in 2 US inpatient clinical pharmacology units.Each participant received either placebo (n = 39), 1 of 3 acetaminophen/opioid combinations (n = 80), or acetaminophen alone (n = 26). Each active treatment included 4 g of acetaminophen daily, the maximum recommended daily dosage. The intended treatment duration was 14 days. Main Outcomes

2006 JAMA Controlled trial quality: predicted high

159. Paracetamol solution or oral suspension (Calpol)

Paracetamol solution or oral suspension (Calpol) Drugs October 2006 Page 1 of 1 Drugs Paracetamol Oral Solution/ Suspension PAR PRESENTATION A solution or suspension containing paracetamol 120 milligrams in 5ml or paracetamol 250 milligrams in 5 ml. ACTIONS Analgesic (pain relieving) and antipyretic (temperature reducing) drug. DOSAGE AND ADMINISTRATION Route: Oral (5ml syringe). Route: Oral (5ml syringe). ADDITIONAL INFORMATION A febrile child should not be left at home except where a full (...) assessment has been carried out, the child has no apparent serious underlying illness and the child is referred to the General Practitioner with the full consent of the parent (or carer). INDICATIONS Relief of mild to moderate pain and/or high temperature. Intended primarily for use in children but may also be applicable to adults. CONTRA-INDICATIONS Known allergy to paracetamol containing products. If a product containing paracetamol (e.g. Calpol, Disprol) has been given within the last four hours

2006 Joint Royal Colleges Ambulance Liaison Committee

160. Upper gastrointestinal complications among users of paracetamol

Upper gastrointestinal complications among users of paracetamol Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2006 DARE.