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Latest & greatest articles for acne
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on acne or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on acne and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
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Acne treatment and clinical papers
Acne is a common skin condition characterised by whiteheads (or blackheads), pimples and oily skin. It can lead to possible scarring. It is typically caused when hair follicles become inflamed and the sebaceous glands in the skin are overactive. The over production of sebum and a combination of dead skin cells and dirt can clog follicles and pores causing a break out. Acne can affect any age group but it’s more common in adolescents.
There are many ways to treat acne depending on the severity of the case. Treatments include a range of medications such as topical retinoids, antibiotics and in severe cases isotretinoin is prescribed. Research is ongoing to determine the side effects and harms caused by these drugs. Clinical trials and studies are vital to assess treatment.
The Trip Database has an extensive collection of articles on acne ranging from clinical trials, systematic reviews, clinical guidelines and case reports. These can be found via searching the site.
Clascoterone (Winlevi) - acne Drug Approval Package: WINLEVI U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: WINLEVI Company: Cassiopea SpA Application Number: 213433 Approval Date: 8/26/2020 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF) (PDF) FDA Application Review Files (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) Date created: September 29, 2020
Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary syndrome. Metformin has been proposed as possibly a safer and more effective long-term treatment than the oral contraceptive pill (OCP) in women with polycystic ovary syndrome (PCOS). It is important to directly compare the efficacy and safety of metformin versus OCP in the long-term treatment of women with PCOS. This is an update of a Cochrane Review comparing insulin
New advice from the MHRA regarding cyproterone acetate: how does this affect prescribing of Co-cyprindiol/Dianette® for acne/hirsutism? July 2020 1 FSRH CEU Statement : New advice from the MHRA regarding cyproterone acetate: how does this affect prescribing of Co-cyprindiol/Dianette ® for acne/hirsutism? 13 July 2020 Background New data from a French cohort study  indicate that use of high dose cyproterone acetate (high dose products contain 50-100mg per tablet) is associated (...) acetate with ethinylestradiol Co-cyprindiol/Dianette ® tablets containing cyproterone acetate with ethinylestradiol are used for treatment of acne and hirsutism in women of reproductive age. In contrast to the high dose products described above, they contain only 2mg of cyproterone acetate; annual cumulative exposure to cyproterone acetate is only about 0.8g. The Yellow Card scheme has received no reports of meningioma associated with use of these low-dose products. The MHRA advises that although
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. Acne is an inflammatory disorder with a high global burden. It is common in adolescents and primarily affects sebaceous gland-rich areas. The clinical benefit of the topical acne treatments azelaic acid, salicylic acid, nicotinamide, sulphur, zinc, and alpha-hydroxy acid is unclear.To assess the effects of topical treatments (azelaic acid, salicylic acid, nicotinamide, zinc, alpha (...) -hydroxy acid, and sulphur) for acne.We searched the following databases up to May 2019: the Cochrane Skin Group Specialised Register, CENTRAL, MEDLINE, Embase, and LILACS. We also searched five trials registers.Clinical randomised controlled trials of the six topical treatments compared with other topical treatments, placebo, or no treatment in people with acne.We used standard methodological procedures expected by Cochrane. Key outcomes included participants' global self-assessment of acne
Faculty Opinions recommendation of Systematic review of the epidemiology of acnevulgaris. Systematic review of the epidemiology of acne... | Faculty Opinions On April 12th, 2020, F1000Prime became Faculty Opinions. See our to learn more. Welcome Guest 1 Recommendations info_outline Systematic Review / Meta-analysis Confirmation close Classified As Confirmation 1 Article Type Systematic Review / Meta-analysis More more_vert close Download article Export article Sciwheel Download citation BibTeX (...) RIS Share Email Systematic review of the epidemiology of acnevulgaris. ARTICLE PUBLISHED: 2020 04 01 CITE AS: Sci Rep. 2020 04 01 ; 10 ( 1 ): 5754 Recommendations Abstract Comments You have reached your article limit. Register for 30-day free trial Registration is free and only takes a moment, or subscribe for unlimited access. Already registered with Faculty Opinions? Sign In Institutional access Recommend Faculty Opinions to your librarian or information manager to request an extended free
Trifarotene (Aklief) - topical treatment of acnevulgaris Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Expand all Summary Basis of Decision (SBD) for Contact: Summary Basis of Decision (SBD) documents provide information related to the original authorization of a product. The for is located below. Recent Activity for SBDs written for approved after September 1
Evaluation of Spin in the Abstracts of Systematic Reviews Regarding the Treatment of AcneVulgaris: Cross-Sectional Analysis (Preprint) JMIR Dermatology - Evaluation of Spin in the Abstracts of Systematic Reviews and Meta-Analyses Focused on the Treatment of AcneVulgaris: Cross-Sectional Analysis Select options Resource Center Journal Information Browse Journal Year: Published on 20.3.2020 in Preprints (earlier versions) of this paper are available at , first published November 08, 2019 (...) . Evaluation of Spin in the Abstracts of Systematic Reviews and Meta-Analyses Focused on the Treatment of AcneVulgaris: Cross-Sectional Analysis Evaluation of Spin in the Abstracts of Systematic Reviews and Meta-Analyses Focused on the Treatment of AcneVulgaris: Cross-Sectional Analysis Authors of this article: ; ; ; ; ; ; ; ; Oklahoma State University Center for Health Sciences, Tulsa, OK, United States Corresponding Author: Ryan Ottwell, BS Oklahoma State University Center for Health Sciences 1111 W
Topical benzoyl peroxide for acne. Acne is a common, economically burdensome condition that can cause psychological harm and, potentially, scarring. Topical benzoyl peroxide (BPO) is a widely used acne treatment; however, its efficacy and safety have not been clearly evaluated.To assess the effects of BPO for acne.We searched the following databases up to February 2019: the Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase, and LILACS. We also searched five trials registers (...) and checked the reference lists of relevant randomised controlled trials (RCTs) and systematic reviews.We included RCTs that compared topical BPO used alone (including different formulations and concentrations of BPO) or as part of combination treatment against placebo, no treatment, or other active topical medications for clinically diagnosed acne (used alone or in combination with other topical drugs not containing BPO) on the face or trunk.We used standard methodological procedures as expected
Acnevulgaris: Benzoyl peroxide Benzoyl peroxide | Prescribing information | Acnevulgaris | CKS | NICE Search CKS… Menu Benzoyl peroxide Acnevulgaris: Benzoyl peroxide Last revised in December 2019 Benzoyl peroxide Benzoyl peroxide Indication and dose for acnevulgaris: For Child 12–17 years — apply to the skin 1–2 times a day, preferably after washing with soap and water and start treatment with lower-strength preparations. For Adult — apply to the skin 1–2 times a day, preferably after (...) peroxide is applied at night and the topical antibiotic in the morning. Avoid using two products that both have an alcoholic base as this may increase skin irritation. A combined proprietary product is available. Benzoyl peroxide combined with a topical retinoid is a useful choice, especially in the maintenance of acne. Apply the products once daily, 12 hours apart (for example the topical retinoid at night and benzoyl peroxide in the morning). Both these drugs can irritate the skin; consider using
Acnevulgaris: Azelaic acid Azelaic acid | Prescribing information | Acnevulgaris | CKS | NICE Search CKS… Menu Azelaic acid Acnevulgaris: Azelaic acid Last revised in December 2019 Azelaic acid How should I prescribe azelaic acid? Indication and dose for acnevulgaris For Child 12–17 years — apply twice daily. In people with sensitive skin, apply once daily for 1 week, then apply twice daily. For Adult — apply twice daily. In people with sensitive skin, apply once daily for 1 week
AcnevulgarisAcnevulgaris | Topics A to Z | CKS | NICE Search CKS… Menu AcnevulgarisAcnevulgaris Last revised in December 2019 Acnevulgaris is a chronic skin condition in which blockage or inflammation of the hair follicles and accompanying sebaceous glands Diagnosis Management Prescribing information Background information Acnevulgaris: Summary Acnevulgaris is a chronic inflammatory skin condition affecting mainly the face, back and chest - it is characterised by blockage (...) and inflammation of the pilosebaceous unit (the hair follicle, hair shaft and sebaceous gland). It presents with lesions which can be non-inflammatory (comedones), inflammatory (papules, pustules and nodules) or a mixture of both. Up to 95% of adolescents in Western industrialized countries are affected by acne to some extent — 20 to 35% develop moderate or severe acne. Complications of acne include skin changes such as scarring, post-inflammatory hyperpigmentation or depigmentation and psychosocial problems
Acnevulgaris in Saudi Arabia: A systematic review Acnevulgaris in Saudi Arabia: A systematic review Alanazi AZ - J Dermatol Dermatol Surg Introduction: Acnevulgaris (AV) is one of the most common dermatological disorders. However, data of AV in Saudi Arabia are not well documented. Purpose: To determine the prevalence, potential risk factors, psychological impact, and treatment modality of AV in the Kingdom of Saudi Arabia and highlights the gaps of knowledge related to this disease. Methods (...) : The literature search was performed using the keywords “acnevulgaris,” “Saudi Arabia,” and “KSA” in four electronic databases: PubMed, Google Scholar, Web of Science, and Embase. The search was restricted by the locational filter of Saudi Arabia and a timeframe of 2010–2019. Results: 453 potentially relevant titles and abstracts being identified, of which 18 articles met the inclusion criteria. AV is becoming more prevalent among the Saudi population, particularly among Saudi women. The knowledge
Hidradenitis suppurativa and acnevulgaris and conglobata—systematic review and meta-analysis Hidradenitis suppurativa and acnevulgaris and conglobata—systematic review and meta-analysis | Biomedical Dermatology | Full Text Search Search all BMC articles Search Hidradenitis suppurativa and acnevulgaris and conglobata—systematic review and meta-analysis , , & , , volume 3 , Article number: 12 ( 2019 ) 1296 Accesses 2 Altmetric Abstract Background Hidradenitis suppurativa (HS) is a chronic (...) inflammatory skin disorder which involves painful nodules and draining abscesses in flexural areas. Acnevulgaris and its more severe variants including acne conglobata and acne fulminans are also disorders involving the follicular unit. Given that follicular obstruction, dilatation and inflammation feature in both HS and acnevulgaris/conglobata, it has been suggested that HS is associated with acnevulgaris/conglobata. Methods The present systematic review and meta-analysis was performed according
Trifarotene (Aklief) - acnevulgaris Drug Approval Package: AKLIEF U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: AKLIEF Company: Galderma Research and Development, LLC Application Number: 211527 Approval Date: 10/04/2019 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF) (PDF) FDA Application Review Files (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF
British Association of Dermatologists guidelines for the management of hidradenitis suppurativa (acne inversa) 4 Fitzroy Square, London W1T 5HQ Tel: 020 7383 0266 Fax: 020 7388 5263 e-mail: firstname.lastname@example.org Registered Charity No. 258474 HIDRADENITIS SUPPURATIVA What are the aims of this leaflet? This leaflet has been written to help you understand more about hidradenitis suppurativa (HS). It tells you what it is, what may cause it, what can be done about it, and where you can find out more (...) system is involved in producing inflammation and treatments that reduce the immune system activity may be helpful (see below). ? In a few people with HS there is a link to the bowel condition Crohn ’s disease. ? There may be a link with acne and pilonidal sinus (a chronic abscess at the base of the spine). ? Smoking and obesity are linked with HS, but the condition can also affect non-smokers of normal weight. ? Poor hygiene does not cause hidradenitis suppurativa. Is hidradenitis suppurativa
Acnevulgaris: What else might it be? Differential diagnosis | Diagnosis | Acnevulgaris | CKS | NICE Search CKS… Menu Differential diagnosis Acnevulgaris: What else might it be? Last revised in December 2019 What else might it be? The differential diagnosis for acne includes: Rosacea — for more information, see the CKS topic on . Perioral dermatitis . Folliculitis and boils — for more information, see the CKS topic on . Drug-induced acne — some drugs can cause or exacerbate acneiform (...) eruptions including dioxins (chloracne), corticosteroids, anti-epileptics (phenytoin and carbamazepine), lithium, isoniazid, vitamins B1, B6 and B12. Keratosis pilaris . Basis for recommendation The information on the differential diagnosis of acne is based on clinical guidelines Evidence-Based Recommendations for the Diagnosis and Treatment of Pediatric Acne [ ], European evidence-based (S3) guideline for the treatment of acne – update 2016 [ ], Guidelines of care for the management of acnevulgaris