Oliceridine (Olinvyk) - To manage acute pain in certain adults Drug Approval Package: OLINVYK U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: OLINVYK Company: Trevena, Inc. Application Number: 210730 Approval Date: 8/7/2020 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF) (PDF) FDA Application Review Files (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF

Identification of very low-risk acute chest pain patients without troponin testing Identification of very low-risk acute chest pain patients without troponin testing - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC: . Get (...) new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Emerg Med J Actions . 2020 Aug 4;emermed-2020-209698. doi: 10.1136/emermed-2020-209698. Online ahead of print. Identification of very low-risk acute chest pain patients without troponin testing

Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health (...) at most: Send even when there aren't any new results Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Review Am J Emerg Med Actions . 2020 Jun 1;38(9):1860-1866. doi: 10.1016/j.ajem.2020.05.094. Online ahead of print. Intranasal ketamine for acute pain management

Comparison of topical capsaicin and topical piroxicam in the treatment of acute trauma-induced pain: A randomized double-blind trial Comparison of topical capsaicin and topical piroxicam in the treatment of acute trauma-induced pain: A randomized double-blind trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 (...) ahead of print. Comparison of topical capsaicin and topical piroxicam in the treatment of acute trauma-induced pain: A randomized double-blind trial , , , , , , , , Affiliations Expand Affiliations 1 Department of Emergency Medicine, Faculty of Medicine, Ataturk University, Erzurum, Turkey. Electronic address: abdullahmrym86@gmail.com. 2 Department of Emergency Medicine, Manisa Merkez Efendi State Hospital, Manisa, Turkey. 3 Department of Emergency Medicine, Bingol State Hospital, Bingol, Turkey. 4

Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving (...) of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis , , , , , , , , , , Collaborators, Affiliations Expand Collaborators Canadian Perioperative Anesthesia Clinical Trials (PACT) Group : , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Affiliation 1 From the Population Health and Optimal Health Practices Research Unit, Trauma-Emergency-Critical Care Medicine, CHU de Québec - Université Laval Research Center

Virtual reality for acute pain in outpatient hysteroscopy: a randomised controlled trial Virtual reality for acute pain in outpatient hysteroscopy: a randomised controlled trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Get the latest public health information from CDC (...) Optional text in email: Save Cancel Create a file for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation BJOG Actions . 2020 Jun 23. doi: 10.1111/1471-0528.16377. Online ahead of print. Virtual reality for acute pain in outpatient hysteroscopy: a randomised controlled trial , , , , , , Affiliations Expand Affiliations 1 Imperial College London, London, UK. 2

An investigation of effective strategies to reduce the risk of transitioning from acute to chronic pain DSEN Abstract: A Rapid Review of Best Practice Guidance to Reduce the Risk of Transition from Acute to Chronic Post-surgical Pain - CIHR Language selection Search and menus Search Search website Search Topics menu You are here: DSEN Abstract A Rapid Review of Best Practice Guidance to Reduce the Risk of Transition from Acute to Chronic Post-surgical Pain *This research was funded by CIHR (...) - Drug Safety and Effectiveness Network What is the issue? In 2018, the WHO and an international working group developed a definition and classification system for chronic pain, thereby advancing the recognition of chronic pain as a health condition, in its own right. Acute pain typically begins due to an identifiable antecedent (e.g., injury, surgery) and occurs for a short duration. This pain serves as a protective factor and typically responds well to analgesics, anti-inflammatories, and non

A Rapid Review of Best Practice Guidance to Reduce the Risk of Transition from Acute to Chronic Post-surgical Pain This research was funded by CIHR – Drug Safety and Effectiveness Network and conducted by investigators affiliated with the following institutions: Summary ? High-quality best practice guidance is lacking for interventions that are generalizable to all surgery patients to reduce the risk of acute post-surgical pain transitioning to chronic. ? Many publications recognized (...) that control of acute post-operative pain was a primary risk factor for transition to chronic pain; however, long-term outcomes such as transition to chronic pain were not provided in supporting evidence for any acute pain management recommendations. ? Specific surgical techniques have been recommended to reduce the risk of transition from acute to chronic post- surgical pain; however, no generalizable interventions for all surgical patients have been strongly recommended within available CPGs or tested

Clinical Study of Spinal Cord Stimulation and Pulsed Radiofrequency for Management of Herpes Zoster-Related Pain Persisting Beyond Acute Phase in Elderly Patients Clinical Study of Spinal Cord Stimulation and Pulsed Radiofrequency for Management of Herpes Zoster-Related Pain Persisting Beyond Acute Phase in Elderly Patients - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other (...) citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Pain Physician Actions . 2020 Jun;23(3):263-270. Clinical Study of Spinal Cord Stimulation and Pulsed Radiofrequency for Management of Herpes Zoster-Related Pain Persisting Beyond Acute Phase in Elderly Patients , , , , , Affiliations Expand Affiliations 1 National Pain Management and Research Center, China-Japan

Analgesic efficacy of cannabinoids for acute pain management after surgery: a systematic review and meta-analysis Analgesic efficacy of cannabinoids for acute pain management after surgery: a systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library (...) displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Reg Anesth Pain Med Actions . 2020 Jul;45(7):509-519. doi: 10.1136/rapm-2020-101340. Epub 2020 May 28. Analgesic efficacy of cannabinoids for acute pain management after surgery: a systematic review and meta-analysis , , , Affiliations Expand Affiliations 1 Anesthesiology and Pain Medicine - North York General Hospital & The Ottawa Hospital, University of Toronto, University of Ottawa, Toronto, Ottawa, Ontario

Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National Library of Medicine National Center (...) Link Copy Actions Cite Share Permalink Copy Page navigation Clin J Pain Actions . 2020 Jun;36(6):458-462. doi: 10.1097/AJP.0000000000000821. Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain , , , , , , , , , , , Affiliations Expand Affiliations 1 Emergency Department, Fattouma Bourguiba University Hospital. 2 Research Laboratory LR12SP18, University of Monastir. 3 Emergency Department, Farhat Hached University Hospital. 4 Emergency Department

Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes (...) Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Clin J Pain Actions . 2020 May;36(5):352-358. doi: 10.1097/AJP.0000000000000805. Investigating the Effect of Perioperative Chlorzoxazone on Acute Postoperative Pain After Total Hip and Knee Replacement Surgery , , , , , , , Affiliations Expand Affiliations 1 Department of Health Science and Technology, Center for Sensory-Motor Interaction (SMI). 2 Orthopaedic Research Unit

Opioid-induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial Opioid-induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health (...) Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Acad Emerg Med Actions . 2020 Mar 27. doi: 10.1111/acem.13946. Online ahead of print. Opioid-induced Euphoria Among Emergency Department Patients With Acute Severe Pain: An Analysis of Data From a Randomized Trial , , , , Affiliations Expand Affiliations 1 From the, Department of Emergency Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY. 2

Acute Nonspecific Chest Pain-Low Probability of Coronary Artery Disease American College of Radiology End User License Agreement ACR Appropriateness Criteria is a registered trademark of the American College of Radiology. By accessing the ACR Appropriateness Criteria®, you expressly agree and consent to the terms and conditions as described at: http://www.acr.org/~/media/ACR/Documents/AppCriteria/TermsandConditions.pdf Personal use of material is permitted for research, scientific (...) and/or information purposes only. You may not modify or create derivative works based on American College of Radiology material. No part of any material posted on the American College of Radiology Web site may be copied, downloaded, stored in a retrieval system, or redistributed for any other purpose without the expressed written permission of American College of Radiology. Date of origin: 1998 Last review date: 2015 ACR Appropriateness Criteria ® 1 Acute Nonspecific Chest Pain–Low Probability of CAD American

Efficacy and safety of multiple doses of tapentadol oral solution in the treatment of moderate to severe acute pain in children aged 2 to <18 years - a randomized, double-blind, placebo-controlled trial Efficacy and Safety of Multiple Doses of Tapentadol Oral Solution in the Treatment of Moderate to Severe Acute Pain in Children Aged 2 to - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History (...) Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation J Pain Res Actions . 2019 Nov 13;12:3099-3112. doi: 10.2147/JPR.S207010. eCollection 2019. Efficacy and Safety of Multiple Doses of Tapentadol Oral Solution in the Treatment of Moderate to Severe Acute Pain in Children Aged 2 to , , , , Affiliations Expand Affiliations 1 Grünenthal GmbH, Aachen, Germany. 2 Division of Paediatric Pharmacology and Pharmacometrics, University

Randomized Clinical Trial of IV Acetaminophen as an Adjunct to IV Hydromorphone for Acute Severe Pain in Emergency Department Patients Randomized Clinical Trial of Intravenous (IV) Acetaminophen as an Adjunct to IV Hydromorphone for Acute Severe Pain in Emergency Department Patients - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several (...) Create a file for external citation management software Create file Cancel Actions Cite Share Permalink Copy Page navigation Acad Emerg Med Actions . 2020 Feb 20. doi: 10.1111/acem.13947. Online ahead of print. Randomized Clinical Trial of Intravenous (IV) Acetaminophen as an Adjunct to IV Hydromorphone for Acute Severe Pain in Emergency Department Patients , , , , , , , Affiliations Expand Affiliation 1 From the, Department of Emergency Medicine, Albert Einstein College of Medicine, Bronx, NY. PMID

Individualized Care Plans for Acute Sickle Cell Pain Crises Individualized Care Plans for Acute Sickle Cell Pain Crises | Emergency Medicine | Washington University in St. Louis Open Menu Back Close Menu Search for: Loading... Welcome Our Team Sections Education Alumni Research ECRC Journal Club Events Jermyn Lectures Open Search If you would like to view the videos from this event, please click the links below. Vignette Mr. J. is a 22 year old male presenting to your urban emergency department (...) for sickle cell pain crises. In the ED, his vital signs are BP 120/70, P 58, RR 18, T 37.0°C, and 100% oxygen saturation on room air. No objective evidence of acute intoxication or trauma are appreciated. He appears extremely uncomfortable and you note that he has been waiting in triage for 6-hours due to ED crowding. Yesterday, you received separate emails from the American College of Emergency Physician’s and the American Medical Association highlighting the role of physician prescribing in the ongoing

Comparison of Intraoperative Sedation With Dexmedetomidine Versus Propofol on Acute Postoperative Pain in Total Knee Arthroplasty Under Spinal Anesthesia: A Randomized Trial In patients undergoing total knee arthroplasty under spinal anesthesia, we compared the postoperative analgesic effect of intraoperative sedation with dexmedetomidine versus propofol. We hypothesized that sedation with dexmedetomidine would result in lower postoperative opioid analgesic consumption than with propofol.Forty (...) observer's assessment of alertness/sedation score of 3 or 4. The cumulative amounts of fentanyl administered via intravenous patient-controlled analgesia were recorded at 24 and 48 hours postoperatively (primary outcome). The postoperative numerical rating scale for pain was assessed at 6, 12, 24, and 48 hours (secondary outcome). The postoperative use of additional rescue analgesic (ketoprofen) and antiemetic drugs was also compared between the 2 groups at 24 and 48 hours.Dexmedetomidine significantly

Ibuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Low Back Pain: An Emergency Department-based Randomized Study Patients with low back pain (LBP) are often treated with nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs are modestly effective for LBP, but many patients with LBP continue to suffer despite treatment with these medications. We compared pain and functional outcomes 1 week after emergency department (ED) discharge among patients randomized to a 1-week course (...) of ibuprofen plus acetaminophen versus ibuprofen plus placebo.This was a randomized, double-blind study conducted in two urban EDs. Patients presenting with acute, nontraumatic, nonradicular LBP of no more than 2 weeks' duration were eligible for enrollment immediately prior to discharge from an ED if they had a score > 5 on the Roland Morris Disability Questionnaire (RMDQ), a 24-item validated instrument, indicating more than minimal functional impairment. All patients were given a standardized 10-minute

Effect of Ubrogepant vs Placebo on Pain and the Most Bothersome Associated Symptom in the Acute Treatment of Migraine: The ACHIEVE II Randomized Clinical Trial. Ubrogepant is an oral calcitonin gene-related peptide receptor antagonist under investigation for acute treatment of migraine.To evaluate the efficacy and tolerability of ubrogepant compared with placebo for acute treatment of a single migraine attack.Phase 3, multicenter, randomized, double-blind, placebo-controlled, single-attack (...) of any dose were nausea (50 mg, 10 of 488 [2.0%]; 25 mg, 12 of 478 [2.5%]; and placebo, 10 of 499 [2.0%]) and dizziness (50 mg, 7 of 488 [1.4%]; 25 mg, 10 of 478 [2.1%]; placebo, 8 of 499 [1.6%]).Among adults with migraine, acute treatment with ubrogepant compared with placebo led to significantly greater rates of pain freedom at 2 hours with 50-mg and 25-mg doses, and absence of the most bothersome migraine-associated symptom at 2 hours only with the 50-mg dose. Further research is needed to assess