Latest & greatest articles for adverse events

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Top results for adverse events

121. Time elapsed after ischemic stroke and risk of adverse cardiovascular events and mortality following elective noncardiac surgery. Full Text available with Trip Pro

Time elapsed after ischemic stroke and risk of adverse cardiovascular events and mortality following elective noncardiac surgery. The timing of surgery in patients with recent ischemic stroke is an important and inadequately addressed issue.To assess the safety and importance of time elapsed between stroke and surgery in the risk of perioperative cardiovascular events and mortality.Danish nationwide cohort study (2005-2011) including all patients aged 20 years or older undergoing elective (...) noncardiac surgeries (n=481,183 surgeries).Time elapsed between stroke and surgery in categories and as a continuous measure.Risk of major adverse cardiovascular events (MACE; including ischemic stroke, acute myocardial infarction, and cardiovascular mortality) and all-cause mortality up to 30 days after surgery. Odds ratios (ORs) were calculated by multivariable logistic regression models.Crude incidence rates of MACE among patients with (n = 7137) and without (n = 474,046) prior stroke were 54.4 (95

2014 JAMA

122. An exploration of the implementation of open disclosure of adverse events in the UK: a scoping review and qualitative exploration

An exploration of the implementation of open disclosure of adverse events in the UK: a scoping review and qualitative exploration Anexplorationoftheimplementation ofopendisclosureofadverseevents intheUK:ascopingreviewand qualitativeexploration Yvonne Birks, 1* Reema Harrison, 2 Kate Bosanquet, 2 Jill Hall, 2 Melissa Harden, 3 Vikki Entwistle, 4 Ian Watt, 2 Peter Walsh, 5 Sarah Ronaldson, 2 David Roberts, 6 Joy Adamson, 2 John Wright 7 and Rick Iedema 8 1 Social Policy Research Unit, University (...) of adverse events, in terms of health care, refers to the practice of telling people if they have been harmed by a mistake when receiving care. In 2009, the National Patient Safety Agency relaunched its Being Open framework to support open disclosure in the UK. We explored how this guidance has been received, combining the literature on open disclosure with findings from interviews. We reviewed the international literature on open disclosure since 1980, identifying over 600 papers, predominantly from

2014 NIHR HTA programme

123. Adverse drug event-related emergency department visits associated with complex chronic conditions Full Text available with Trip Pro

Adverse drug event-related emergency department visits associated with complex chronic conditions Outpatient adverse drug events (ADEs) can result in serious outcomes requiring emergency department (ED) visits and hospitalizations. The incidence and severity of ADEs in children with complex chronic conditions (CCCs), who often take multiple medications, is unknown. We sought to describe the characteristics of ADE-related ED visits, including association with CCC status; determine the implicated

2014 EvidenceUpdates

124. Coding of adverse events of suicidality in clinical study reports of duloxetine for the treatment of major depressive disorder: descriptive study. Full Text available with Trip Pro

Coding of adverse events of suicidality in clinical study reports of duloxetine for the treatment of major depressive disorder: descriptive study. To assess the effects of coding and coding conventions on summaries and tabulations of adverse events data on suicidality within clinical study reports.Systematic electronic search for adverse events of suicidality in tables, narratives, and listings of adverse events in individual patients within clinical study reports. Where possible, for each (...) event we extracted the original term reported by the investigator, the term as coded by the medical coding dictionary, medical coding dictionary used, and the patient's trial identification number. Using the patient's trial identification number, we attempted to reconcile data on the same event between the different formats for presenting data on adverse events within the clinical study report.9 randomised placebo controlled trials of duloxetine for major depressive disorder submitted

2014 BMJ

125. Risk of Thiazide-Induced Metabolic Adverse Events in Older Adults Full Text available with Trip Pro

Risk of Thiazide-Induced Metabolic Adverse Events in Older Adults To evaluate the risk and predictors of thiazide-induced adverse events (AEs) in multimorbid older adults in real-world clinical settings.Observational cohort study.National Veterans Affairs data from 2007 to 2008.Veterans aged 65 and older newly prescribed a thiazide (N = 1,060) compared with propensity-matched nonusers of antihypertensive medications (N = 1,060).The primary outcome was a composite of metabolic AEs defined

2014 EvidenceUpdates

126. Developing a risk model for in-hospital adverse events following implantable cardioverter-defibrillator implantation: a report from the NCDR (National Cardiovascular Data Registry) Full Text available with Trip Pro

Developing a risk model for in-hospital adverse events following implantable cardioverter-defibrillator implantation: a report from the NCDR (National Cardiovascular Data Registry) To better inform patients and physicians of the expected risk of adverse events and to assist hospitals' efforts to improve the outcomes of patients undergoing implantable cardioverter-defibrillator (ICD) implantation, we developed and validated a risk model using data from the NCDR (National Cardiovascular Data (...) Registry) ICD Registry.ICD prolong life in selected patients, but ICD implantation carries the risk of periprocedural complications.We analyzed data from 240,632 ICD implantation procedures between April 1, 2010, and December 31, 2011 in the registry. The study group was divided into a derivation (70%) and a validation (30%) cohort. Multivariable logistic regression was used to identify factors associated with in-hospital adverse events (complications or mortality). A parsimonious risk score

2014 EvidenceUpdates

127. Safe Administration of Systemic Cancer Therapy Part 2: Administration of Chemotherapy and Management of Preventable Adverse Events

Safe Administration of Systemic Cancer Therapy Part 2: Administration of Chemotherapy and Management of Preventable Adverse Events Safe Administration of Systemic Cancer Therapy Part 2: Administration of Systemic Treatment and Management of Preventable Adverse Events | Cancer Care Ontario Google Tag Manager You are using an outdated browser. We suggest you update your browser for a better experience. for update. Browse Guidelines Browse Pathway Maps Sort by You are here Safe Administration (...) of Systemic Cancer Therapy Part 2: Administration of Systemic Treatment and Management of Preventable Adverse Events Guideline Objective To provide guidance on processes, technologies and devices for the prevention and control of adverse effects that can happen during or following the administration of systemic treatment to adult cancer patients. Patient Population Adult patients who are going to receive chemotherapy treatment or are already receiving chemotherapy treatment for cancer. Intended Guideline

2014 Cancer Care Ontario

128. Case control study: Higher levels of nurse staffing are not associated with reduced adverse events among postoperative children if surveillance levels are low

Case control study: Higher levels of nurse staffing are not associated with reduced adverse events among postoperative children if surveillance levels are low Higher levels of nurse staffing are not associated with reduced adverse events among postoperative children if surveillance levels are low | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about (...) how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Higher levels of nurse staffing are not associated with reduced adverse events among

2014 Evidence-Based Nursing

129. Is Ambulatory Laparoscopic Roux-En-Y Gastric Bypass Associated With Higher Adverse Events? (Abstract)

Is Ambulatory Laparoscopic Roux-En-Y Gastric Bypass Associated With Higher Adverse Events? To determine the impact of length of stay upon 30-day outcomes.It has been recommended the goal length of stay (LOS) after laparoscopic Roux-en-Y gastric bypass (LRYGB) should be 1 day to improve resource utilization. This study's aim was to assess LRYGB outcomes by LOS.Data were obtained from the BOLD (Bariatric Outcomes Longitudinal Database) for 51,788 laparoscopic gastric bypass (LRYGB) procedures

2014 EvidenceUpdates

130. Systematic review and meta-analysis: Need for standardising adverse event reporting in testosterone trials

Systematic review and meta-analysis: Need for standardising adverse event reporting in testosterone trials Need for standardising adverse event reporting in testosterone trials | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Need for standardising adverse event reporting in testosterone trials Article Text Aetiology Systematic review and meta-analysis Need for standardising adverse event reporting in testosterone trials Shehzad Basaria

2014 Evidence-Based Medicine

131. Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle. Full Text available with Trip Pro

Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle. Handoff miscommunications are a leading cause of medical errors. Studies comprehensively assessing handoff improvement programs are lacking.To determine whether introduction of a multifaceted handoff program was associated with reduced rates of medical errors and preventable adverse events, fewer omissions of key data in written handoffs, improved verbal (...) handoff tool linked to the electronic medical record was introduced.The primary outcomes were the rates of medical errors and preventable adverse events measured by daily systematic surveillance. The secondary outcomes were omissions in the printed handoff document and resident time-motion activity.Medical errors decreased from 33.8 per 100 admissions (95% CI, 27.3-40.3) to 18.3 per 100 admissions (95% CI, 14.7-21.9; P < .001), and preventable adverse events decreased from 3.3 per 100 admissions (95

2013 JAMA

132. Autoimmune, neurological, and venous thromboembolic adverse events after immunisation of adolescent girls with quadrivalent human papillomavirus vaccine in Denmark and Sweden: cohort study. Full Text available with Trip Pro

Autoimmune, neurological, and venous thromboembolic adverse events after immunisation of adolescent girls with quadrivalent human papillomavirus vaccine in Denmark and Sweden: cohort study. To assess the risk of serious adverse events after vaccination of adolescent girls with quadrivalent human papillomavirus (qHPV) vaccine.Register based cohort study.Denmark and Sweden, October 2006 to December 2010.997,585 girls aged 10-17, among whom 296,826 received a total of 696,420 qHPV vaccine (...) . The rate ratios for five neurological events were not significantly increased and there were inverse associations with epilepsy (rate ratio 0.66, 95% confidence interval 0.54 to 0.80) and paralysis (0.56, 0.35 to 0.90). There was no association between exposure to qHPV vaccine and venous thromboembolism (0.86, 0.55 to 1.36).This large cohort study found no evidence supporting associations between exposure to qHPV vaccine and autoimmune, neurological, and venous thromboembolic adverse events. Although

2013 BMJ

133. Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents. Full Text available with Trip Pro

Risk of major adverse cardiac events following noncardiac surgery in patients with coronary stents. Guidelines recommend delaying noncardiac surgery in patients after coronary stent procedures for 1 year after drug-eluting stents (DES) and for 6 weeks after bare metal stents (BMS). The evidence underlying these recommendations is limited and conflicting.To determine risk factors for adverse cardiac events in patients undergoing noncardiac surgery following coronary stent implantation.A national (...) , retrospective cohort study of 41,989 Veterans Affairs (VA) and non-VA operations occurring in the 24 months after a coronary stent implantation between 2000 and 2010. Nonlinear generalized additive models examined the association between timing of surgery and stent type with major adverse cardiac events (MACE) adjusting for patient, surgery, and cardiac risk factors. A nested case-control study assessed the association between perioperative antiplatelet cessation and MACE.A composite 30-day MACE rate of all

2013 JAMA

134. Surgical adverse events: a systematic review

Surgical adverse events: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

135. Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: a systematic review

Severe adverse events during antiviral therapy in hepatitis C virus cirrhotic patients: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

136. Aliskiren increased adverse events in patients with diabetes and kidney disease who were receiving ACE inhibitors or ARBs. (Abstract)

Aliskiren increased adverse events in patients with diabetes and kidney disease who were receiving ACE inhibitors or ARBs. 23552833 2013 05 13 2013 04 04 1539-3704 158 6 2013 Mar 19 Annals of internal medicine Ann. Intern. Med. ACP Journal Club. Aliskiren increased adverse events in patients with diabetes and kidney disease who were receiving ACE inhibitors or ARBs. JC7 10.7326/0003-4819-158-6-201303190-02007 de Leeuw Peter W PW Maastricht University Medical Centre and Cardiovascular Research

2013 Annals of Internal Medicine

137. Adverse events associated with EUS and EUS with FNA

Adverse events associated with EUS and EUS with FNA GUIDELINE Adverse events associated with EUS and EUS with FNA This is one of a series of statements discussing the use of GI endoscopy in common clinical situations. The Stan- dards of Practice Committee of the American Society for Gastrointestinal Endoscopy prepared this text. In prepar- ing this document, a search of the medical literature was performed by using PubMed. Additional references were obtained from the bibliographies (...) nodes, often in close proximity to large vascular structures. EUS uses dedicated echoendoscopes that have unique optical and mechanical properties be- yond the addition of a US transducer. The incidence and types of adverse events associated with EUS differ from those seen with other endoscopic procedures and are attributable to the use of FNA. This guideline focuses on the adverse events speci?cally associated with EUS and EUS-FNA. Adverse events associated with sedation and standard endoscopic

2013 American Society for Gastrointestinal Endoscopy

138. Cohort study: Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin

Cohort study: Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin Article Text Aetiology Cohort study Lack

2013 Evidence-Based Medicine

139. Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs

Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we (...) are associated with fewer adverse events than TCAs Article Text Therapeutics Review: SSRIs and TCAs equally effective at treating chronic depression and dysthemia; SSRIs are associated with fewer adverse events than TCAs Statistics from Altmetric.com Question Question: What is the efficacy and acceptability of selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs) in the treatment of chronic depression? Outcomes: Primary efficacy outcome: response to treatment, defined as ≥50

2013 Evidence-Based Mental Health

140. Adults with psychosis or psychotic experiences may report adverse life events prior to the onset of symptoms but direction of causality cannot be inferred

Adults with psychosis or psychotic experiences may report adverse life events prior to the onset of symptoms but direction of causality cannot be inferred Adults with psychosis or psychotic experiences may report adverse life events prior to the onset of symptoms but direction of causality cannot be inferred | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time (...) . To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Adults with psychosis or psychotic experiences may report adverse life events

2013 Evidence-Based Mental Health