Latest & greatest articles for anaesthesia

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Anaesthesia

Clinical Anaesthesia is used to induce a temporary medical state of controlled unconsciousness, inducing a loss of sensation or awareness. There are three main types of Anaesthesia:

  • Local and Regional
  • General
  • Sedation

Anaesthesia is primarily used during surgical procedures to block pain. While unconscious, blood flow and heart rate is monitored.

Research and development in the use of Anaesthesia has helped anesthesiologists in the progression of patient safety before and after surgery and medical procedures. The developments and research of Anaesthesia through the years has massively influences medicine and surgery today.

Case studies and clinical trials help aid researchers in the development of aftercare during postoperative recovery. Research is a vital part in the field of Anaesthesia, it allows anesthesiologists to improve the delivery of patient safety while unconscious.

Learn more on the emerging technology in Anaesthesia and the advancements in Anaesthesia practise by searching Trip.

Top results for anaesthesia

241. Evaluation of a continuous monitoring and feedback initiative to improve quality of anaesthetic care: a mixed-methods quasi-experimental study Full Text available with Trip Pro

Evaluation of a continuous monitoring and feedback initiative to improve quality of anaesthetic care: a mixed-methods quasi-experimental study Evaluation of a continuous monitoring and feedback initiative to improve quality of anaesthetic care: a mixed-methods quasi-experimental study Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from (...) , London, UK 2 Department of Anaesthesia, Imperial College Healthcare NHS Trust, London, UK 3 IQ Scientific Institute for Quality of Healthcare, Radboud University Medical Centre, Nijmegen, the Netherlands 4 Department of Anaesthesia, Royal Lancaster Infirmary, Lancaster, UK 5 School of Public Health, Imperial College London, London, UK 6 Centre for Perioperative Medicine and Critical Care Research, Imperial College Healthcare NHS Trust, London, UK * Corresponding author Email: {{metadata.Journal

2015 NIHR HTA programme

242. Periprosthetic Anesthetic for Postoperative Pain After Laparoscopic Ventral Hernia Repair: A Randomized Clinical Trial Full Text available with Trip Pro

Periprosthetic Anesthetic for Postoperative Pain After Laparoscopic Ventral Hernia Repair: A Randomized Clinical Trial Laparoscopic ventral hernia repair (LVHR) using mesh is a well-established intervention for ventral hernia, but pain control can be challenging.To determine whether instillation of a long-acting local anesthetic between the mesh and the peritoneum after LVHR reduces pain or narcotic requirements.A prospective, double-blind, randomized clinical trial with data collection during (...) a brief hospital stay in a tertiary care, community teaching hospital over 3 years between December 15, 2011, and March 28, 2014. Of 120 screened patients undergoing LVHR in this intention-to-treat analysis, 99 eligible patients were randomized. Forty-two patients received the study drug, and 38 patients received placebo. Patients with a history of chronic narcotic use were excluded.After mesh placement, a long-acting local anesthetic (bupivacaine hydrochloride, 0.50%) or placebo (0.9% normal saline

2015 EvidenceUpdates Controlled trial quality: predicted high

243. Non-pharmacological interventions for assisting the induction of anaesthesia in children. Full Text available with Trip Pro

Non-pharmacological interventions for assisting the induction of anaesthesia in children. Induction of general anaesthesia can be distressing for children. Non-pharmacological methods for reducing anxiety and improving co-operation may avoid the adverse effects of preoperative sedation.To assess the effects of non-pharmacological interventions in assisting induction of anaesthesia in children by reducing their anxiety, distress or increasing their co-operation.In this updated review we searched (...) in trials.We included 28 trials (2681 children) investigating 17 interventions of interest; all trials were conducted in high-income countries. Overall we judged the trials to be at high risk of bias. Except for parental acupuncture (graded low), all other GRADE assessments of the primary outcomes of comparisons were very low, indicating a high degree of uncertainty about the overall findings. Parental presence: In five trials (557 children), parental presence at induction of anaesthesia did not reduce

2015 Cochrane

244. Peribulbar versus retrobulbar anaesthesia for cataract surgery. Full Text available with Trip Pro

Peribulbar versus retrobulbar anaesthesia for cataract surgery. Cataract is a major cause of blindness worldwide. Unless medically contraindicated, cataract surgery is usually performed under local (regional) anaesthesia. Local anaesthesia involves the blockage of a nerve subserving a given part of the body. It involves infiltration of the area around the nerve with local anaesthetic. The two main approaches in the eye are retrobulbar and peribulbar. There is debate over whether the peribulbar (...) a subgroup analysis for globe akinesia.We included six trials involving 1438 participants. Three of the six trials had adequate sequence generation while all the trials had unclear allocation concealment There was no evidence of any difference in pain perception during surgery with either retrobulbar or peribulbar anaesthesia. Both were largely effective. There was no evidence of any difference in complete akinesia or the need for further injections of local anaesthetic. Conjunctival chemosis was more

2015 Cochrane

245. Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial Full Text available with Trip Pro

Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial Patients undergoing emergency procedures under general anesthesia have impaired gastric emptying and are at high risk for aspiration of gastric contents. Erythromycin has strong gastric prokinetic properties.To evaluate the efficacy of erythromycin lactobionate in gastric emptying in patients undergoing emergency surgery.The Erythro-Emerge trial was a single-center (...) , randomized, double-blinded, placebo-controlled clinical trial in patients undergoing emergency surgery under general anesthesia at Geneva University Hospitals. We included 132 patients from March 25, 2009, through April 10, 2013, and all patients completed the study. Randomization was stratified for trauma and nontrauma procedures. The randomization code was opened on April 23, 2013, and analyses were performed through July 26, 2013. We performed an intention-to-treat analysis.Patients were randomized

2015 EvidenceUpdates Controlled trial quality: predicted high

246. Perioperative local infiltration anesthesia with ropivacaine has no effect on postoperative pain after total hip arthroplasty Full Text available with Trip Pro

Perioperative local infiltration anesthesia with ropivacaine has no effect on postoperative pain after total hip arthroplasty The local infiltration analgesia (LIA) technique has been widely used to reduce opioid requirements and to improve postoperative mobilization following total hip arthroplasty (THA). However, the evidence for the efficacy of LIA in THA is not yet clear. We determined whether single-shot LIA in addition to a multimodal analgesic regimen would reduce acute postoperative (...) pain and opioid requirements after THA.116 patients undergoing primary THA under spinal anesthesia were included in this randomized, double-blind, placebo-controlled trial. All patients received oral opioid-sparing multimodal analgesia: etoricoxib, acetaminophen, and glucocorticoid. The patients were randomized to receive either 150 mL ropivacaine (2 mg/mL) and 0.5 mL epinephrine (1 mg/mL) or 150 mL 0.9% saline. Rescue analgesic consisted of morphine and oxycodone as needed. The primary endpoint

2015 EvidenceUpdates Controlled trial quality: predicted high

247. In suspected corneal foreign body should local anaesthetic be applied before or after eye examination?

Strategy Medline using the NHS Evidence interface 1946 to present date of searching 14/04/15: exp EYE FOREIGN BODIES/ AND exp ANESTHESIA, LOCAL/ OR exp ANESTHETICS, LOCAL/ OR local adj2 anaesthe$.ti,ab. EMBASE using the NHS Evidence interface 1974 to present date of searching 14/04/15: exp INTRAOCULAR FOREIGN BODY/ OR exp LOCAL ANESTHETIC AGENT/ OR exp ANESTHESIA, LOCAL OR OR local adj2 anaesthe$.ti,ab. The Cochrane Library Issue 4 of 12 April 2015: ((MeSH descriptor: [Eye Foreign Bodies] explode all (...) trees OR MeSH descriptor: [Eye Injuries] explode all trees) AND MeSH descriptor: [Anesthesia, Local])) explode all trees. Search Outcome Eighty-three unique records were identified of which none addressed the clinical question. Comment(s) The use of local anaesthetic in the gritty eye with a suspected foreign body prior to examination is common to give patients quick symptomatic relief. However, there is no evidence whether this should be done before or after eye examination. Clinical Bottom Line

2015 BestBETS

248. Regional (spinal, epidural, caudal) versus general anaesthesia in preterm infants undergoing inguinal herniorrhaphy in early infancy. Full Text available with Trip Pro

having general anaesthesia for inguinal hernia surgery at a postmature age have at least one apnoeic episode within the postoperative period. Research studies have failed to adequately distinguish the effects of apnoeic episodes from other complications of extreme preterm gestation on the risk of brain injury, or to investigate the potential impact of postoperative apnoea upon longer term neurodevelopment. In addition to episodes of apnoea, there are concerns that anaesthetic and sedative agents may (...) have a direct toxic effect on the developing brain of preterm infants even after reaching postmature age. It is proposed that regional anaesthesia may reduce the risk of postoperative apnoea, avoid the risk of anaesthetic-related neurotoxicity and improve neurodevelopmental outcomes in preterm infants requiring surgery for inguinal hernia at a postmature age.To determine if regional anaesthesia reduces postoperative apnoea, bradycardia, the use of assisted ventilation, and neurological impairment

2015 Cochrane

249. Deep Sedation and General Anaesthesia in Young Children

than children who did not. 1 The second SR concluded that early anaesthesia exposure resulted in moderately increased odds of behavioral or developmental issues. 2 One SR 3 examined anaesthesia-related pediatric mortality and found an anaesthesia- related mortality rate of less than one death per 10,000 anesthetics in Brazil and developed countries. Five non-randomized studies 4-8 were identified. One study 4 examined the safety of deep sedation for pediatric patients with sickle cell disease (...) with and without developmental disabilities: sedation medication requirements and adverse events related to sedation. Pediatr Emerg Care. 2012 Oct;28(10):1036-40. PubMed: PM23023474 7. Stockton E, Hughes M, Broadhead M, Taylor A, McEwan A. A prospective audit of safety issues associated with general anesthesia for pediatric cardiac magnetic resonance imaging. Paediatr Anaesth. 2012 Nov;22(11):1087-93. PubMed: PM22458837 Deep Sedation and General Anaesthesia in Young Children 5 8. Ozer L, Oktem ZB, Kucukyavuz Z

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

250. Anaesthetic Agents in Pregnant Women Undergoing Non-Obstetric Surgical or Endoscopic Procedures

recommend deep sedation, when needed, be administered by an anesthesia provider” Page 23 Very low quality; any estimate of effect is very uncertain ASGE = American Society of Gastrointestinal Endoscopy; GRADE = Grading of Recommendations Assessment, Development and Evaluation. Anaesthetic Agents in Pregnant Women Undergoing Surgical or Endoscopic Procedures 18 APPENDIX 5: Additional References of Potential Interest Safety of Anaesthesia for Caesarean Section Afolayan JM, Nwachukwu CE, Esangbedo ES, Omu (...) : a prospective study. Acta Anaesthesiol Scand. 2010 Jan;54(1):46- 54. Anaesthetic Agents in Pregnant Women Undergoing Surgical or Endoscopic Procedures 19 Fyneface-Ogan S, Uzoigwe SA. Caesarean section outcome in eclamptic patients: a comparison of infiltration and general anaesthesia. West Afr J Med. 2008 Oct;27(4):250-4. Gori F, Pasqualucci A, Corradetti F, Milli M, Peduto VA. Maternal and neonatal outcome after cesarean section: the impact of anesthesia. J Matern Fetal Neonatal Med. 2007 Jan;20(1):53-7

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

251. Global surgical and anaesthetic task shifting: a systematic literature review and survey. (Abstract)

clinicians were commonly supervised (100% [four countries] for surgery and 90% [20 countries] for anaesthesia). In low-income countries, associate clinicians undertook surgical and anaesthetic procedures without supervision (100% for surgery [five countries] and 100% for anaesthesia [22 countries]).Task shifting is used to augment the global surgical workforce across all geographical regions and income groups. Associate clinicians are ubiquitous among the global surgical workforce and should (...) Global surgical and anaesthetic task shifting: a systematic literature review and survey. Billions of people worldwide lack access to surgical care; this is in part driven by severe shortages in the global surgical workforce. Task shifting, the movement of tasks to associate clinicians or non-specialist physicians, is a commonly implemented yet often contentious strategy to expand the surgical workforce. A more complete understanding of the global distribution and use of surgical

2015 Lancet

252. Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered

pain during caries excavation when the patient has not received anesthesia? Clinical Bottom Line For patients in need of caries excavation who will not allow or have contraindications to the use of local anesthetic, Er:YAG lasers are less likely than rotary burs to cause a patient discomfort. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Dommisch/2008 26 adults with 102 carious lesions Randomized (...) Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered UTCAT2881, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Er:YAG Lasers Are Less Likely Than Rotary Burs to Cause a Patient Discomfort During Caries Excavation When No Anesthesia Has Been Administered Clinical Question Are lasers less likely than rotary burs to cause a patient

2015 UTHSCSA Dental School CAT Library

253. Application of Oraqix (Lidocaine/Prilocaine Local Anesthetic Gel) Reduces Pain During Scaling and Root Planing

Application of Oraqix (Lidocaine/Prilocaine Local Anesthetic Gel) Reduces Pain During Scaling and Root Planing UTCAT2833, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Application of Oraqix (Lidocaine/Prilocaine Local Anesthetic Gel) Reduces Pain During Scaling and Root Planing Clinical Question For an adult patient with periodontitis, does applying Oraqix (lidocaine/prilocaine local anesthetic gel) effectively (...) reduce the patient’s pain during scaling and root planing compared to scaling and root planing with placebo? Clinical Bottom Line Scaling and root planing in conjunction with the application of Oraqix (lidocaine/prilocaine local anesthetic gel) is less painful for adult periodontitis patients than scaling and root planing with placebo. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Magnusson/2005 337

2015 UTHSCSA Dental School CAT Library

254. Anaesthetic and sedative agents used for electrical cardioversion. Full Text available with Trip Pro

Anaesthetic and sedative agents used for electrical cardioversion. Electrical cardioversion is an effective procedure for restoring normal sinus rhythm in the hearts of patients with irregular heart rhythms. It is important that the patient is not fully conscious during the procedure, as it can be painful and distressing. The drug used to make patients unaware of the procedure should rapidly achieve the desired level of sedation, should wear off quickly and should not cause cardiovascular (...) or respiratory side effects.We aimed to compare the safety, effectiveness and adverse events associated with various anaesthetic or sedative agents used in direct current cardioversion for cardiac arrhythmia in both elective and emergency settings.We sought answers to the following specific questions.• Which drugs deliver the best outcomes for patients undergoing electrical cardioversion?• Does using a particular agent confer advantages or disadvantages?• Is additional analgesic necessary to prevent pain?We

2015 Cochrane

255. Effect of Sedative Premedication on Patient Experience After General Anesthesia: A Randomized Clinical Trial. Full Text available with Trip Pro

Effect of Sedative Premedication on Patient Experience After General Anesthesia: A Randomized Clinical Trial. Sedative premedication is widely administered before surgery, but little clinical evidence supports its use.To assess the efficacy of sedative premedication on perioperative patient experience.A randomized clinical trial, the PremedX study, enrolled 1062 adult patients who were younger than 70 years and had been scheduled for various elective surgeries under general anesthesia at 5 (...) minutes) for the placebo group (P < .001) and the rate of early cognitive recovery was 51% (95% CI, 45%-56%), 71% (95% CI, 66%-76%), and 64% (95% CI, 59%-69%), respectively (P < .001).Among patients undergoing elective surgery under general anesthesia, sedative premedication with lorazepam compared with placebo or no premedication did not improve the self-reported patient experience the day after surgery, but was associated with modestly prolonged time to extubation and a lower rate of early cognitive

2015 JAMA Controlled trial quality: predicted high

256. Does Topical Anesthetic Reduce Pain During Intraosseous Pin Removal in Children? A Randomized Controlled Trial Full Text available with Trip Pro

Does Topical Anesthetic Reduce Pain During Intraosseous Pin Removal in Children? A Randomized Controlled Trial The purpose of this study was to determine the effectiveness of topical liposomal lidocaine in reducing the pain perceived by children undergoing percutaneous intraosseous pin (PP) removal in the outpatient orthopaedic clinic.A triple-blinded, randomized, placebo-controlled clinical trial comparing topical liposomal lidocaine to a placebo was conducted at the Stollery Children's

2015 EvidenceUpdates Controlled trial quality: predicted high

257. Anesthetic neurotoxicity--clinical implications of animal models. Full Text available with Trip Pro

Anesthetic neurotoxicity--clinical implications of animal models. Some anesthetics and sedatives have been shown to cause neurotoxic effects in laboratory animals. The FDA collaboration SmartTots recommends undertaking large-scale clinical studies and avoiding nonurgent surgical procedures requiring anesthesia in children younger than 3 years of age.

2015 NEJM

258. Anesthesia Information Management Systems for Patients Undergoing Surgery

infusion were detected, and anesthesia providers were notified via "pop-up" computer screen messages. AIMS data were retrospectively analyzed to evaluate the effect of SAM notification messages on hypotensive and hypertensive episodes. RESULTS: For anesthetic cases 12 months before (N = 16913) and after (N = 17132) institution of SAM messages, the median duration of hypotensive episodes with concurrent high MAC decreased with notifications (Mann Whitney rank sum test, P = 0.031). However, the reduction (...) , received general anaesthesia. In this period, only 378 (23%) patients experienced PONV within 24 h after operation. This difference is statistically significant (P=0.01). CONCLUSION: Automated reminders can improve patient outcome by improving guideline adherence. Guidelines and Recommendations No literature identified. PREPARED BY: Canadian Agency for Drugs and Technologies in Health Tel: 1-866-898-8439 www.cadth.ca Anesthesia Information Management Systems for Patients Undergoing Surgery 5 APPENDIX

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

259. The use of local anaesthetic lubrication for the catheterisation of males

. Medline 1950—present ((exp ANESTHETICS, LOCAL/ OR exp LIDOCAINE/ OR exp ANESTHESIA, LOCAL) OR Lidocaine.ti,ab. OR Lignocaine.ti,ab. OR Optilube.ti,ab OR Instillagel.ti,ab OR (exp LUBRICATION or exp LUBRICANTS)) AND ((exp CATHETERS, INDWELLING/ OR exp URINARY, CATHETERS/) OR (Urinary AND Catheter.ti,ab. OR (Bladder AND Catheter.ti,ab.) OR (Indwelling AND Catheter.ti,ab.) OR (In-dwelling AND Catheter).ti,ab. OR (Urethral AND Catheter.ti,ab))) [Limit to: Humans and (age groups all adults 19 plus years (...) )] Embase ((exp BLADDER CATHETERIZATION/ OR exp URETHRAL CATHETERIZATION) OR (urinary AND catheter$).ti,ab. OR (urethral AND catheter$).ti,ab. OR (bladder AND catheter$).ti,ab. OR (indwelling AND catheter$).ti,ab. OR (in-dwelling AND catheter$).ti,ab.) AND ((exp LOCAL ANESTHETIC AGENT / OR exp LIDOCAINE / OR exp LOCAL ANESTHESIA) OR (Lidocaine).ti,ab. OR (Lignocaine).ti,ab OR (exp LUBRICATING AGENT) OR (Lubricating AND Gel).ti,ab. OR (lubrica$).ti,ab. OR (Instillagel).ti,ab. OR (Optilube).ti,ab.) [Limit

2015 BestBETS

260. Effect of Topical Anesthetics on Vaccine

and the product monograph of the vaccine to be administered identified that efficacy of the vaccine had not been researched with topical anesthetic. The Canadian Immunization Guide (CIG) states, “There is no evidence that the application of a topical local anaesthetic poses a risk of decreased immune response to vaccines if the topical anaesthetic is used as directed in the product leaflet and only for the ages 2 recommended by the manufacturer.” However, the evidence on which this statement is made (...) with the use of anesthetics. 8 Similarly, the CDC guideline concludes that anesthetic cream does not interfere with immune response to MMR vaccine. It does not refer to the evidence about the effect of topical anesthetics on other childhood immunizations such as Tetanus, acellular pertussis, polio virus, Hib, and Hep B vaccines. The Taddio clinical practice guideline recommends the use of topical anaesthetics during immunization of children, as the evidence demonstrated that topical anesthetics

2015 Peel Health Library